{"id":"https://openalex.org/W4293100766","doi":"https://doi.org/10.21203/rs.3.rs-1397146/v1","title":"Biogenesis and Characterization of Proficient Silver Nanoparticles Employing Marine Procured Fungi Hamigera Pallida and Assessment of their Antioxidative, Antimicrobial and Anticancer Potency on Human Breast Cancer (MCF-7) Cell Line","display_name":"Biogenesis and Characterization of Proficient Silver Nanoparticles Employing Marine Procured Fungi Hamigera Pallida and Assessment of their Antioxidative, Antimicrobial and Anticancer Potency on Human Breast Cancer (MCF-7) Cell Line","publication_year":2022,"publication_date":"2022-03-21","ids":{"openalex":"https://openalex.org/W4293100766","doi":"https://doi.org/10.21203/rs.3.rs-1397146/v1"},"language":"en","primary_location":{"id":"doi:10.21203/rs.3.rs-1397146/v1","doi":"https://doi.org/10.21203/rs.3.rs-1397146/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-1397146/v1","pdf_url":"https://www.researchsquare.com/article/rs-1397146/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.researchsquare.com/article/rs-1397146/latest.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004463496","display_name":"Harsh Mistry","orcid":"https://orcid.org/0000-0001-8650-0548","observed_orcids":["https://orcid.org/0000-0001-8650-0548"]},"institutions":[{"id":"https://openalex.org/I335036346","display_name":"Hemchandracharya North Gujarat University","ror":"https://ror.org/049sxg896","country_code":"IN","type":"education","lineage":["https://openalex.org/I335036346"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Harsh Mistry","raw_affiliation_strings":["Hemchandracharya North Gujarat University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hemchandracharya North Gujarat University","institution_ids":["https://openalex.org/I335036346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016474719","display_name":"Rashmi Thakor","orcid":"https://orcid.org/0000-0003-2272-1362","observed_orcids":["https://orcid.org/0000-0003-2272-1362"]},"institutions":[{"id":"https://openalex.org/I335036346","display_name":"Hemchandracharya North Gujarat University","ror":"https://ror.org/049sxg896","country_code":"IN","type":"education","lineage":["https://openalex.org/I335036346"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rashmi Thakor","raw_affiliation_strings":["Hemchandracharya North Gujarat University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hemchandracharya North Gujarat University","institution_ids":["https://openalex.org/I335036346"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020317264","display_name":"Himanshu Bariya","orcid":"https://orcid.org/0000-0003-3059-6338","observed_orcids":["https://orcid.org/0000-0003-3059-6338","https://orcid.org/0000-0001-5796-8918"]},"institutions":[{"id":"https://openalex.org/I335036346","display_name":"Hemchandracharya North Gujarat University","ror":"https://ror.org/049sxg896","country_code":"IN","type":"education","lineage":["https://openalex.org/I335036346"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Himanshu S Bariya","raw_affiliation_strings":["Hemchandracharya North Gujarat University"],"raw_orcid":"https://orcid.org/0000-0003-3059-6338","affiliations":[{"raw_affiliation_string":"Hemchandracharya North Gujarat University","institution_ids":["https://openalex.org/I335036346"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5020317264"],"corresponding_institution_ids":["https://openalex.org/I335036346"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13232","display_name":"Laser-Ablation Synthesis of Nanoparticles","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/silver-nanoparticles","display_name":"silver nanoparticles","score":0.9950000047683716},{"id":"https://openalex.org/keywords/biosynthesis","display_name":"biosynthesis","score":0.8069999814033508},{"id":"https://openalex.org/keywords/marine-fungi","display_name":"marine fungi","score":0.9819999933242798},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.6200000047683716},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9879999756813049},{"id":"https://openalex.org/keywords/free-radical-scavenging-activity","display_name":"free radical scavenging","score":0.8410000205039978},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.8980000019073486},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8759999871253967},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.9039999842643738},{"id":"https://openalex.org/keywords/cell-free-filtrate","display_name":"cell-free filtrate","score":0.7599999904632568},{"id":"https://openalex.org/keywords/dpph-radical","display_name":"DPPH radical","score":0.5609999895095825},{"id":"https://openalex.org/keywords/band-gap","display_name":"band gap","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C109541995","wikidata":"https://www.wikidata.org/wiki/Q1881253","display_name":"MCF-7","level":5,"score":0.8683953285217285},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.7190737128257751},{"id":"https://openalex.org/C2994372470","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell lines","level":4,"score":0.6234670877456665},{"id":"https://openalex.org/C57992300","wikidata":"https://www.wikidata.org/wiki/Q2066956","display_name":"Potency","level":3,"score":0.6059361100196838},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.5719389319419861},{"id":"https://openalex.org/C2994423619","wikidata":"https://www.wikidata.org/wiki/Q9103","display_name":"Human breast","level":4,"score":0.5691977739334106},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5105427503585815},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37538352608680725},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.35253000259399414},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35183611512184143},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3305708169937134},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3221397399902344},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.25751519203186035},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.16109159588813782},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.10630309581756592},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10579812526702881},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07610899209976196},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.059239476919174194}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21203/rs.3.rs-1397146/v1","doi":"https://doi.org/10.21203/rs.3.rs-1397146/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-1397146/v1","pdf_url":"https://www.researchsquare.com/article/rs-1397146/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.21203/rs.3.rs-1397146/v1","doi":"https://doi.org/10.21203/rs.3.rs-1397146/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-1397146/v1","pdf_url":"https://www.researchsquare.com/article/rs-1397146/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4293100766.pdf","grobid_xml":"https://content.openalex.org/works/W4293100766.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1448086140","https://openalex.org/W1964968948","https://openalex.org/W1993847869","https://openalex.org/W2032979719","https://openalex.org/W2082925126","https://openalex.org/W2339843614","https://openalex.org/W2562717314","https://openalex.org/W2567978278","https://openalex.org/W2607293408","https://openalex.org/W2781525129","https://openalex.org/W2791638785","https://openalex.org/W2794353941","https://openalex.org/W2810784676","https://openalex.org/W2886203573","https://openalex.org/W2940279580","https://openalex.org/W2945792041","https://openalex.org/W2962453303","https://openalex.org/W2972586133","https://openalex.org/W2981929794","https://openalex.org/W2991798787","https://openalex.org/W3033955601","https://openalex.org/W3043510467","https://openalex.org/W3086758234","https://openalex.org/W3092593061","https://openalex.org/W3096776276","https://openalex.org/W3100312059","https://openalex.org/W3198740146","https://openalex.org/W4242584716"],"related_works":["https://openalex.org/W4289653964","https://openalex.org/W4384305755","https://openalex.org/W3086758234","https://openalex.org/W4225428160","https://openalex.org/W3163165617","https://openalex.org/W2999851571","https://openalex.org/W7028760777","https://openalex.org/W3106528561","https://openalex.org/W2593720231","https://openalex.org/W2983332939"],"abstract_inverted_index":{"Abstract":[0],"Objectives":[1],"To":[2],"assess":[3],"the":[4,33,54,69,72,129,187,199],"anticancer":[5,171,219],"potential":[6,157],"of":[7,26,94,114,119,132,190,204,211],"biosynthesized":[8,136],"silver":[9,27,133],"nanoparticles":[10,28],"using":[11],"marine":[12],"derived":[13],"fungi":[14],"Hamigera":[15,212],"pallida":[16,213],"with":[17,89,186],"their":[18],"antibacterial":[19],"and":[20,80,105,148,218],"antioxidant":[21],"activities.":[22],"Results":[23],"The":[24,124,135],"biosynthesis":[25],"(AgNPs)":[29],"was":[30],"assessed":[31],"by":[32,158,206],"change":[34],"in":[35,71],"color":[36],"from":[37,100],"bright":[38],"yellow":[39],"to":[40,76,102,140],"dark":[41],"brown.":[42],"UV-Visible":[43],"spectroscopy":[44,52],"revealed":[45,53,63,85,109,128,198],"its":[46,59,64,86],"stability":[47],"at":[48,183],"429":[49],"nm;":[50],"ATR-FTIR":[51],"functional":[55],"group":[56],"responsible":[57],"for":[58,201],"production;":[60],"X-Ray":[61],"Diffraction":[62],"crystalline":[65],"FCC":[66],"structure":[67],"resembling":[68],"peaks":[70],"XRD":[73],"pattern,":[74],"corresponding":[75],"(110),":[77],"(111),":[78],"(200),":[79],"(311)":[81],"planes;":[82],"TEM":[83],"imaging":[84],"spherical":[87],"morphology":[88],"an":[90,215],"average":[91],"particle":[92],"size":[93],"5.85":[95],"\u00b1":[96,174,192],"0.84":[97],"nm":[98,104],"ranging":[99],"3.69":[101],"16.11":[103],"Tauc's":[106],"plot":[107],"analysis":[108],"a":[110,122],"band":[111],"gap":[112],"energy":[113],"2.22":[115],"eV,":[116],"revealing":[117],"aptitude":[118],"AgNPs":[120,137,168,205],"as":[121,214],"semiconductors.":[123],"subsequent":[125],"characterization":[126],"results":[127],"effective":[130],"synthesis":[131],"nanoparticles.":[134],"were":[138],"found":[139],"have":[141],"significant":[142],"antimicrobial":[143],"effect":[144],"against":[145,164,176],"three":[146,149],"Gram-positive":[147],"Gram-negative":[150],"bacteria.":[151],"They":[152],"also":[153],"demonstrated":[154],"higher":[155],"antioxidative":[156,217],"demonstrating":[159],"strong":[160],"radical":[161],"scavenging":[162],"activity":[163,172],"DPPH":[165],"(2,":[166],"2-diphenyl-1-picrylhydrazyl).":[167],"showed":[169],"highest":[170],"(62.69":[173],"1.73%)":[175],"human":[177],"breast":[178],"cancer":[179],"(MCF-7)":[180],"cell":[181],"line":[182],"100":[184],"\u00b5g/mL":[185],"IC50":[188],"value":[189],"66.07":[191],"2.17":[193],"\u00b5g/mL.":[194],"Conclusions":[195],"This":[196],"study":[197],"prospect":[200],"further":[202],"utilization":[203],"Cell":[207],"free":[208],"filtrate":[209],"(CFF)":[210],"antibacterial,":[216],"agents.":[220]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2022-08-26T00:00:00"}
