{"id":"https://openalex.org/W4292837014","doi":"https://doi.org/10.1016/j.foodchem.2022.133897","title":"Peptides inhibiting angiotensin-I-converting enzyme: Isolation from flavourzyme hydrolysate of Protaetia brevitarsis larva protein and identification","display_name":"Peptides inhibiting angiotensin-I-converting enzyme: Isolation from flavourzyme hydrolysate of Protaetia brevitarsis larva protein and identification","publication_year":2022,"publication_date":"2022-08-23","ids":{"openalex":"https://openalex.org/W4292837014","doi":"https://doi.org/10.1016/j.foodchem.2022.133897","pmid":"https://pubmed.ncbi.nlm.nih.gov/36037683"},"language":"en","primary_location":{"id":"doi:10.1016/j.foodchem.2022.133897","doi":"https://doi.org/10.1016/j.foodchem.2022.133897","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.foodchem.2022.133897","pdf_url":null,"source":{"id":"https://openalex.org/S98026630","display_name":"Food Chemistry","issn_l":"0308-8146","issn":["0308-8146","1873-7072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100387467","display_name":"Jae Hoon Lee","orcid":"https://orcid.org/0000-0002-7440-6842","observed_orcids":["https://orcid.org/0000-0002-7440-6842"]},"institutions":[{"id":"https://openalex.org/I4210114577","display_name":"Korea Food Research Institute","ror":"https://ror.org/028jp5z02","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210114577","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae Hoon Lee","raw_affiliation_strings":["Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea","institution_ids":["https://openalex.org/I4210114577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100657829","display_name":"Tae\u2010Kyung Kim","orcid":"https://orcid.org/0000-0002-6349-4314","observed_orcids":["https://orcid.org/0000-0002-6349-4314"]},"institutions":[{"id":"https://openalex.org/I4210114577","display_name":"Korea Food Research Institute","ror":"https://ror.org/028jp5z02","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210114577","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Tae-Kyung Kim","raw_affiliation_strings":["Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-6349-4314","affiliations":[{"raw_affiliation_string":"Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea","institution_ids":["https://openalex.org/I4210114577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054567472","display_name":"Hae In Yong","orcid":"https://orcid.org/0000-0003-0970-4496","observed_orcids":["https://orcid.org/0000-0003-0970-4496"]},"institutions":[{"id":"https://openalex.org/I4210114577","display_name":"Korea Food Research Institute","ror":"https://ror.org/028jp5z02","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210114577","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hae In Yong","raw_affiliation_strings":["Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea","institution_ids":["https://openalex.org/I4210114577"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ji Yoon Cha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114577","display_name":"Korea Food Research Institute","ror":"https://ror.org/028jp5z02","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210114577","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji Yoon Cha","raw_affiliation_strings":["Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea","institution_ids":["https://openalex.org/I4210114577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088247112","display_name":"Kyung\u2010Mo Song","orcid":"https://orcid.org/0000-0001-8691-8573","observed_orcids":["https://orcid.org/0000-0001-8691-8573"]},"institutions":[{"id":"https://openalex.org/I4210114577","display_name":"Korea Food Research Institute","ror":"https://ror.org/028jp5z02","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210114577","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyung-Mo Song","raw_affiliation_strings":["Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea","institution_ids":["https://openalex.org/I4210114577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101689653","display_name":"Hyo-Geun Lee","orcid":"https://orcid.org/0000-0002-7594-4984","observed_orcids":["https://orcid.org/0000-0002-7594-4984"]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyo Geun Lee","raw_affiliation_strings":["Department of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089219710","display_name":"Jun-Geon Je","orcid":"https://orcid.org/0000-0002-5598-097X","observed_orcids":["https://orcid.org/0000-0002-5598-097X"]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jun-Geon Je","raw_affiliation_strings":["Department of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101882979","display_name":"Min\u2010Cheol Kang","orcid":"https://orcid.org/0000-0002-9658-9045","observed_orcids":["https://orcid.org/0000-0002-9658-9045"]},"institutions":[{"id":"https://openalex.org/I4210114577","display_name":"Korea Food Research Institute","ror":"https://ror.org/028jp5z02","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210114577","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Min-Cheol Kang","raw_affiliation_strings":["Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea","institution_ids":["https://openalex.org/I4210114577"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059995518","display_name":"Yun\u2010Sang Choi","orcid":"https://orcid.org/0000-0001-8060-6237","observed_orcids":["https://orcid.org/0000-0001-8060-6237"]},"institutions":[{"id":"https://openalex.org/I4210114577","display_name":"Korea Food Research Institute","ror":"https://ror.org/028jp5z02","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210114577","https://openalex.org/I4210144908","https://openalex.org/I4387152098"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Yun-Sang Choi","raw_affiliation_strings":["Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea. Electronic address: kcys0517@kfri.re.kr","Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0001-8060-6237","affiliations":[{"raw_affiliation_string":"Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea. Electronic address: kcys0517@kfri.re.kr","institution_ids":["https://openalex.org/I4210114577"]},{"raw_affiliation_string":"Research Group of Food Processing, Korea Food Research Institute, Wanju 55365, Republic of Korea","institution_ids":["https://openalex.org/I4210114577"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5059995518","https://openalex.org/A5101882979"],"corresponding_institution_ids":["https://openalex.org/I4210114577"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":3.8572,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.94293212,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"399","issue":null,"first_page":"133897","last_page":"133897"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/angiotensin-converting-enzyme-inhibitory-peptides","display_name":"angiotensin I-converting enzyme inhibitory peptides","score":0.9190000295639038},{"id":"https://openalex.org/keywords/protaetia-brevitarsis","display_name":"Protaetia brevitarsis","score":0.9179999828338623},{"id":"https://openalex.org/keywords/enzymatic-hydrolysis","display_name":"enzymatic hydrolysis","score":0.7860000133514404},{"id":"https://openalex.org/keywords/flavourzyme","display_name":"Flavourzyme","score":0.9210000038146973},{"id":"https://openalex.org/keywords/antihypertensive-peptides","display_name":"antihypertensive peptides","score":0.8420000076293945},{"id":"https://openalex.org/keywords/nitric-oxide-production","display_name":"nitric oxide production","score":0.8870000243186951},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.9089999794960022},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.8339999914169312},{"id":"https://openalex.org/keywords/functional-food-ingredients","display_name":"functional food ingredients","score":0.7319999933242798},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C28800991","wikidata":"https://www.wikidata.org/wiki/Q15634405","display_name":"Hydrolysate","level":3,"score":0.8158774375915527},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8092042803764343},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4916298985481262},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.47680971026420593},{"id":"https://openalex.org/C63179538","wikidata":"https://www.wikidata.org/wiki/Q854422","display_name":"Gel permeation chromatography","level":3,"score":0.4641125798225403},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.4464718699455261},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4376303255558014},{"id":"https://openalex.org/C27016395","wikidata":"https://www.wikidata.org/wiki/Q128861","display_name":"Angiotensin-converting enzyme","level":3,"score":0.4229898750782013},{"id":"https://openalex.org/C97428945","wikidata":"https://www.wikidata.org/wiki/Q15305109","display_name":"Fractionation","level":2,"score":0.41257452964782715},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.3642716705799103},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09723353385925293},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.06567203998565674},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000809","descriptor_name":"Angiotensins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007703","descriptor_name":"Peptidyl-Dipeptidase A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010450","descriptor_name":"Endopeptidases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011492","descriptor_name":"Protein Hydrolysates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.foodchem.2022.133897","doi":"https://doi.org/10.1016/j.foodchem.2022.133897","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.foodchem.2022.133897","pdf_url":null,"source":{"id":"https://openalex.org/S98026630","display_name":"Food Chemistry","issn_l":"0308-8146","issn":["0308-8146","1873-7072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Chemistry","raw_type":"journal-article"},{"id":"pmid:36037683","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36037683","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W35611082","https://openalex.org/W1884462977","https://openalex.org/W1970944124","https://openalex.org/W1972504016","https://openalex.org/W1979401649","https://openalex.org/W2001408043","https://openalex.org/W2002976335","https://openalex.org/W2008980822","https://openalex.org/W2008999753","https://openalex.org/W2014470979","https://openalex.org/W2022308709","https://openalex.org/W2031777004","https://openalex.org/W2051949556","https://openalex.org/W2072698279","https://openalex.org/W2074665772","https://openalex.org/W2075679088","https://openalex.org/W2075994784","https://openalex.org/W2113248767","https://openalex.org/W2116717490","https://openalex.org/W2509014222","https://openalex.org/W2534187687","https://openalex.org/W2589631716","https://openalex.org/W2604229814","https://openalex.org/W2699544910","https://openalex.org/W2805978477","https://openalex.org/W2905592421","https://openalex.org/W2972467173","https://openalex.org/W3046819369","https://openalex.org/W3082747055","https://openalex.org/W3085967257","https://openalex.org/W3093303674","https://openalex.org/W3107528220","https://openalex.org/W3109132531","https://openalex.org/W3111824730","https://openalex.org/W3112454644","https://openalex.org/W3120305119","https://openalex.org/W3135530243","https://openalex.org/W3180420897","https://openalex.org/W3190780298","https://openalex.org/W3201415925"],"related_works":["https://openalex.org/W2200030569","https://openalex.org/W2004805031","https://openalex.org/W2905592421","https://openalex.org/W1219228310","https://openalex.org/W2034795014","https://openalex.org/W2123660903","https://openalex.org/W2607095515","https://openalex.org/W2267158317","https://openalex.org/W4412693394","https://openalex.org/W2006874229"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-08-24T00:00:00"}