{"id":"https://openalex.org/W4292791499","doi":"https://doi.org/10.1016/j.amjoto.2022.103555","title":"Smoking and other patient factors in HPV-mediated oropharynx cancer: A retrospective cohort study","display_name":"Smoking and other patient factors in HPV-mediated oropharynx cancer: A retrospective cohort study","publication_year":2022,"publication_date":"2022-08-06","ids":{"openalex":"https://openalex.org/W4292791499","doi":"https://doi.org/10.1016/j.amjoto.2022.103555","pmid":"https://pubmed.ncbi.nlm.nih.gov/36037765"},"language":"en","primary_location":{"id":"doi:10.1016/j.amjoto.2022.103555","doi":"https://doi.org/10.1016/j.amjoto.2022.103555","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.amjoto.2022.103555","pdf_url":null,"source":{"id":"https://openalex.org/S204216521","display_name":"American Journal of Otolaryngology","issn_l":"0196-0709","issn":["0196-0709","1532-818X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Journal of Otolaryngology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.amjoto.2022.103555","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045463689","display_name":"Kelly Schostag","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelly Schostag","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066326745","display_name":"Patrick T. Lynch","orcid":"https://orcid.org/0000-0001-8127-5812","observed_orcids":["https://orcid.org/0000-0001-8127-5812"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick T. Lynch","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034786494","display_name":"Taylor Leavitt","orcid":"https://orcid.org/0000-0001-8076-4542","observed_orcids":["https://orcid.org/0000-0001-8076-4542"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taylor Leavitt","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000204424","display_name":"Baran D. Sumer","orcid":"https://orcid.org/0000-0002-8371-4388","observed_orcids":["https://orcid.org/0000-0002-8371-4388"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Baran D. Sumer","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087625451","display_name":"Alex M. Yang","orcid":"https://orcid.org/0000-0002-5109-6968","observed_orcids":["https://orcid.org/0000-0002-5109-6968"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alex Yang","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Avni Shah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Avni Shah","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078193847","display_name":"Thomas R. Emmet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas R. Emmet","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011724315","display_name":"David Jonathan Sher","orcid":"https://orcid.org/0000-0003-3943-7480","observed_orcids":["https://orcid.org/0000-0003-3943-7480"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J. Sher","raw_affiliation_strings":["Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":null,"display_name":"Andrew T. Day","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew T. Day","raw_affiliation_strings":["Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America. Electronic address: andrew.day@utsouthwestern.edu","Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America. Electronic address: andrew.day@utsouthwestern.edu","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"Department of Otolaryngology-Head and Neck Surgery, UT Southwestern Medical Center, Dallas, TX, United States of America","institution_ids":["https://openalex.org/I867280407"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I867280407"],"apc_list":{"value":2970,"currency":"USD","value_usd":2970},"apc_paid":null,"fwci":1.9838,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.86501617,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"43","issue":"5","first_page":"103555","last_page":"103555"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hpv-positive-oropharyngeal-cancer","display_name":"HPV-positive oropharyngeal cancer","score":0.9369999766349792},{"id":"https://openalex.org/keywords/smoking-history","display_name":"smoking history","score":0.8159999847412109},{"id":"https://openalex.org/keywords/pack-years","display_name":"pack-years","score":0.8690000176429749},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.8679999709129333},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.734000027179718},{"id":"https://openalex.org/keywords/disease-specific-survival","display_name":"disease-specific survival","score":0.9480000138282776},{"id":"https://openalex.org/keywords/tobacco-use","display_name":"tobacco use","score":0.7059999704360962},{"id":"https://openalex.org/keywords/patient-age","display_name":"patient age","score":0.5809999704360962},{"id":"https://openalex.org/keywords/ajcc-stage","display_name":"AJCC stage","score":0.652999997138977},{"id":"https://openalex.org/keywords/treatment-paradigm","display_name":"treatment paradigm","score":0.45399999618530273},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7200000286102295},{"id":"https://openalex.org/keywords/oncologic-outcomes","display_name":"oncological outcomes","score":0.6620000004768372},{"id":"https://openalex.org/keywords/curative-treatment","display_name":"curative treatment","score":0.5609999895095825},{"id":"https://openalex.org/keywords/head-and-neck-cancer","display_name":"head and neck cancer","score":0.5979999899864197},{"id":"https://openalex.org/keywords/hpv-16-18","display_name":"HPV 16/18","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9626550674438477},{"id":"https://openalex.org/C119060515","wikidata":"https://www.wikidata.org/wiki/Q1916617","display_name":"Interquartile range","level":2,"score":0.7929002642631531},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.7527722120285034},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6855649352073669},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6683177351951599},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5247949361801147},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.49929022789001465},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.4596514105796814},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43241140246391296},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4152371287345886},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3735932409763336},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.3581399619579315},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.22862356901168823}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009959","descriptor_name":"Oropharyngeal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D052685","descriptor_name":"Alphapapillomavirus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.amjoto.2022.103555","doi":"https://doi.org/10.1016/j.amjoto.2022.103555","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.amjoto.2022.103555","pdf_url":null,"source":{"id":"https://openalex.org/S204216521","display_name":"American Journal of Otolaryngology","issn_l":"0196-0709","issn":["0196-0709","1532-818X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Journal of Otolaryngology","raw_type":"journal-article"},{"id":"pmid:36037765","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36037765","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of otolaryngology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.amjoto.2022.103555","doi":"https://doi.org/10.1016/j.amjoto.2022.103555","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.amjoto.2022.103555","pdf_url":null,"source":{"id":"https://openalex.org/S204216521","display_name":"American Journal of Otolaryngology","issn_l":"0196-0709","issn":["0196-0709","1532-818X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Journal of Otolaryngology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":65,"referenced_works":["https://openalex.org/W1502426806","https://openalex.org/W1557569948","https://openalex.org/W1913875977","https://openalex.org/W1966571450","https://openalex.org/W1981663682","https://openalex.org/W1986471490","https://openalex.org/W1989789581","https://openalex.org/W1999533140","https://openalex.org/W2000445173","https://openalex.org/W2025578423","https://openalex.org/W2054121888","https://openalex.org/W2059796825","https://openalex.org/W2066259480","https://openalex.org/W2068329398","https://openalex.org/W2107709622","https://openalex.org/W2110664940","https://openalex.org/W2124891284","https://openalex.org/W2135924160","https://openalex.org/W2139124456","https://openalex.org/W2139766596","https://openalex.org/W2146488048","https://openalex.org/W2155891858","https://openalex.org/W2163971880","https://openalex.org/W2167489015","https://openalex.org/W2280894559","https://openalex.org/W2296585338","https://openalex.org/W2328544537","https://openalex.org/W2411556531","https://openalex.org/W2502134830","https://openalex.org/W2521061481","https://openalex.org/W2523498413","https://openalex.org/W2568195227","https://openalex.org/W2574207883","https://openalex.org/W2579941249","https://openalex.org/W2592783575","https://openalex.org/W2593603277","https://openalex.org/W2619358949","https://openalex.org/W2742417192","https://openalex.org/W2763263441","https://openalex.org/W2766671181","https://openalex.org/W2770799031","https://openalex.org/W2774655557","https://openalex.org/W2780390594","https://openalex.org/W2792929591","https://openalex.org/W2804861361","https://openalex.org/W2900751234","https://openalex.org/W2901263658","https://openalex.org/W2901385432","https://openalex.org/W2917986559","https://openalex.org/W2924642225","https://openalex.org/W2927581815","https://openalex.org/W2937959913","https://openalex.org/W2967453129","https://openalex.org/W2969616333","https://openalex.org/W2999011949","https://openalex.org/W2999099062","https://openalex.org/W3002867078","https://openalex.org/W3005362969","https://openalex.org/W3087980712","https://openalex.org/W3094628705","https://openalex.org/W3120374595","https://openalex.org/W3122345229","https://openalex.org/W3196999924","https://openalex.org/W3197914863","https://openalex.org/W3210105851"],"related_works":["https://openalex.org/W7160091745","https://openalex.org/W4414574467","https://openalex.org/W2804861361","https://openalex.org/W3162523603","https://openalex.org/W3015436533","https://openalex.org/W2134722714","https://openalex.org/W3152542717","https://openalex.org/W3118644046","https://openalex.org/W3087980712","https://openalex.org/W2903456675"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-08-23T00:00:00"}