{"id":"https://openalex.org/W4292499239","doi":"https://doi.org/10.33448/rsd-v11i11.33594","title":"Doen\u00e7a de alzheimer: atividade anticolinester\u00e1sica das plantas aliment\u00edcias n\u00e3o convencionais (PANC) uma revis\u00e3o integrativa narrativa","display_name":"Doen\u00e7a de alzheimer: atividade anticolinester\u00e1sica das plantas aliment\u00edcias n\u00e3o convencionais (PANC) uma revis\u00e3o integrativa narrativa","publication_year":2022,"publication_date":"2022-08-20","ids":{"openalex":"https://openalex.org/W4292499239","doi":"https://doi.org/10.33448/rsd-v11i11.33594"},"language":"pt","primary_location":{"id":"doi:10.33448/rsd-v11i11.33594","doi":"https://doi.org/10.33448/rsd-v11i11.33594","is_oa":true,"landing_page_url":"https://doi.org/10.33448/rsd-v11i11.33594","pdf_url":"https://rsdjournal.org/index.php/rsd/article/download/33594/30212","source":{"id":"https://openalex.org/S2739064124","display_name":"Research Society and Development","issn_l":"2525-3409","issn":["2525-3409"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310312449","host_organization_name":"Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ci\u00eancias","host_organization_lineage":["https://openalex.org/P4310312449"],"host_organization_lineage_names":["Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ci\u00eancias"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research, Society and Development","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://rsdjournal.org/index.php/rsd/article/download/33594/30212","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086866635","display_name":"Idonilton da Concei\u00e7\u00e3o Fernandes","orcid":"https://orcid.org/0000-0003-4728-4488","observed_orcids":["https://orcid.org/0000-0003-4728-4488","https://orcid.org/0000-0002-2984-9070"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Idonilton da Concei\u00e7\u00e3o Fernandes","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0003-4728-4488","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053856697","display_name":"Daniela Regina Buch Leite","orcid":"https://orcid.org/0000-0003-0675-2003","observed_orcids":["https://orcid.org/0000-0003-0675-2003"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daniela Regina Buch Leite","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0003-0675-2003","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004708398","display_name":"Cleiber Marcio Flores","orcid":"https://orcid.org/0000-0002-2123-6800","observed_orcids":["https://orcid.org/0000-0002-2123-6800"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cleiber Marcio Flores","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0002-2123-6800","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006202488","display_name":"Karen Mary Mantovani","orcid":"https://orcid.org/0000-0003-1684-4008","observed_orcids":["https://orcid.org/0000-0003-1684-4008"]},"institutions":[{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Karen Mary Mantovani","raw_affiliation_strings":["Universit\u00e9 de Poitiers"],"raw_orcid":"https://orcid.org/0000-0003-1684-4008","affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Poitiers","institution_ids":["https://openalex.org/I32881790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061216186","display_name":"Vin\u00edcius Bednarczuk de Oliveira","orcid":"https://orcid.org/0000-0001-7821-7742","observed_orcids":["https://orcid.org/0000-0001-7821-7742"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Vin\u00edcius Bednarczuk de Oliveira","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0001-7821-7742","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086116192","display_name":"Luciane Dalarmi","orcid":"https://orcid.org/0000-0001-8217-2487","observed_orcids":["https://orcid.org/0000-0001-8217-2487"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luciane Dalarmi","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0001-8217-2487","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025756918","display_name":"Deise Prehs Montrucchio","orcid":"https://orcid.org/0000-0003-1440-7007","observed_orcids":["https://orcid.org/0000-0003-1440-7007"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Deise Prehs Montrucchio","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0003-1440-7007","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079201832","display_name":"Josiane de F\u00e1tima Gaspari Dias","orcid":"https://orcid.org/0000-0002-8548-8505","observed_orcids":["https://orcid.org/0000-0002-8548-8505"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Josiane de Fatima Gaspari Dias","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0002-8548-8505","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011506092","display_name":"Mar\u00edlis Dallarmi Miguel","orcid":"https://orcid.org/0000-0002-1126-9211","observed_orcids":["https://orcid.org/0000-0002-1126-9211"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marilis Dallarmi Miguel","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0002-1126-9211","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037832424","display_name":"Obd\u00falio Gomes Miguel","orcid":"https://orcid.org/0000-0002-2231-9130","observed_orcids":["https://orcid.org/0000-0002-2231-9130"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Obdulio Gomes Miguel","raw_affiliation_strings":["Universidade Federal do Paran\u00e1"],"raw_orcid":"https://orcid.org/0000-0002-2231-9130","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1","institution_ids":["https://openalex.org/I52418104"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1293,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.35881456,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"11","issue":"11","first_page":"e199111133594","last_page":"e199111133594"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.5175999999046326,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.5175999999046326,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection","score":0.3955000042915344,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.07090000063180923,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/acetylcholinesterase-inhibition","display_name":"acetylcholinesterase inhibition","score":0.8420000076293945},{"id":"https://openalex.org/keywords/unconventional-food-plants","display_name":"non-conventional food plants","score":0.7979999780654907},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.7580000162124634},{"id":"https://openalex.org/keywords/plant-metabolites","display_name":"plant metabolites","score":0.7229999899864197},{"id":"https://openalex.org/keywords/natural-products","display_name":"natural products","score":0.45399999618530273},{"id":"https://openalex.org/keywords/alzheimer-s-disease-treatment","display_name":"Alzheimer's disease treatment","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.6251824498176575},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3304136395454407},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3213385343551636},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.21610182523727417}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.33448/rsd-v11i11.33594","doi":"https://doi.org/10.33448/rsd-v11i11.33594","is_oa":true,"landing_page_url":"https://doi.org/10.33448/rsd-v11i11.33594","pdf_url":"https://rsdjournal.org/index.php/rsd/article/download/33594/30212","source":{"id":"https://openalex.org/S2739064124","display_name":"Research Society and Development","issn_l":"2525-3409","issn":["2525-3409"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310312449","host_organization_name":"Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ci\u00eancias","host_organization_lineage":["https://openalex.org/P4310312449"],"host_organization_lineage_names":["Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ci\u00eancias"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research, Society and Development","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.33448/rsd-v11i11.33594","doi":"https://doi.org/10.33448/rsd-v11i11.33594","is_oa":true,"landing_page_url":"https://doi.org/10.33448/rsd-v11i11.33594","pdf_url":"https://rsdjournal.org/index.php/rsd/article/download/33594/30212","source":{"id":"https://openalex.org/S2739064124","display_name":"Research Society and Development","issn_l":"2525-3409","issn":["2525-3409"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310312449","host_organization_name":"Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ci\u00eancias","host_organization_lineage":["https://openalex.org/P4310312449"],"host_organization_lineage_names":["Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ci\u00eancias"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research, Society and Development","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.40450000762939453,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4292499239.pdf","grobid_xml":"https://content.openalex.org/works/W4292499239.grobid-xml"},"referenced_works_count":84,"referenced_works":["https://openalex.org/W1469267021","https://openalex.org/W1522233097","https://openalex.org/W1828391690","https://openalex.org/W1939290175","https://openalex.org/W1952455177","https://openalex.org/W1963482508","https://openalex.org/W1986696049","https://openalex.org/W1990482856","https://openalex.org/W2011490130","https://openalex.org/W2014741665","https://openalex.org/W2016021175","https://openalex.org/W2018194053","https://openalex.org/W2039697813","https://openalex.org/W2053379937","https://openalex.org/W2053967340","https://openalex.org/W2054004741","https://openalex.org/W2066596424","https://openalex.org/W2070981957","https://openalex.org/W2076893290","https://openalex.org/W2078249472","https://openalex.org/W2083787857","https://openalex.org/W2084172837","https://openalex.org/W2093594935","https://openalex.org/W2094119272","https://openalex.org/W2104397087","https://openalex.org/W2112054387","https://openalex.org/W2118217274","https://openalex.org/W2145120002","https://openalex.org/W2180913335","https://openalex.org/W2266920672","https://openalex.org/W2335875095","https://openalex.org/W2338259230","https://openalex.org/W2340987784","https://openalex.org/W2510391362","https://openalex.org/W2530109242","https://openalex.org/W2562610851","https://openalex.org/W2578078648","https://openalex.org/W2602208369","https://openalex.org/W2618930976","https://openalex.org/W2624478957","https://openalex.org/W2624931236","https://openalex.org/W2736125240","https://openalex.org/W2740887733","https://openalex.org/W2740983178","https://openalex.org/W2761894533","https://openalex.org/W2772942437","https://openalex.org/W2789634221","https://openalex.org/W2790027629","https://openalex.org/W2795738620","https://openalex.org/W2805257646","https://openalex.org/W2810309666","https://openalex.org/W2890128687","https://openalex.org/W2892194280","https://openalex.org/W2911082113","https://openalex.org/W2914224421","https://openalex.org/W2916082310","https://openalex.org/W2927435434","https://openalex.org/W2946239546","https://openalex.org/W2962276396","https://openalex.org/W2995951489","https://openalex.org/W2997888154","https://openalex.org/W3001830331","https://openalex.org/W3002490460","https://openalex.org/W3010052916","https://openalex.org/W3012290946","https://openalex.org/W3030852002","https://openalex.org/W3042157101","https://openalex.org/W3056264410","https://openalex.org/W3118615836","https://openalex.org/W3126281386","https://openalex.org/W3128700804","https://openalex.org/W3133683891","https://openalex.org/W3138745614","https://openalex.org/W3159698272","https://openalex.org/W3165316373","https://openalex.org/W3165826780","https://openalex.org/W3185184038","https://openalex.org/W3193679168","https://openalex.org/W3195040746","https://openalex.org/W3198378842","https://openalex.org/W3204125099","https://openalex.org/W3212160121","https://openalex.org/W4229496361","https://openalex.org/W4297888959"],"related_works":["https://openalex.org/W2996485314","https://openalex.org/W4206227022","https://openalex.org/W2919153814","https://openalex.org/W3048605251","https://openalex.org/W1516270637","https://openalex.org/W4412636112","https://openalex.org/W2028171795","https://openalex.org/W7120404367","https://openalex.org/W1592189619","https://openalex.org/W4387311683"],"abstract_inverted_index":{"Objetivo:":[0],"Realizar":[1],"uma":[2],"revis\u00e3o":[3],"integrativa":[4],"narrativa":[5],"sobre":[6],"plantas":[7,50,156],"aliment\u00edcias":[8,36],"n\u00e3o":[9,37,107],"convencionais":[10,38],"(PANC),":[11],"que":[12,46,110],"apresentam":[13],"a\u00e7\u00e3o":[14],"inibit\u00f3ria":[15],"da":[16,82,133,153],"enzima":[17],"acetilcolinesterase,":[18],"utilizando":[19,74],"para":[20,94,116,143,151],"isso":[21],"as":[22],"bases":[23,52],"de":[24,44,49,53,65,70,135,148],"dados":[25,54],"mais":[26],"consultadas":[27],"na":[28,146],"atualidade;":[29],"elencar":[30],"os":[31,75],"metabolitos":[32],"identificados":[33,86],"nas":[34,51],"esp\u00e9cies":[35],"com":[39,128],"aplica\u00e7\u00e3o":[40],"anticolinesterasica.":[41],"M\u00e9todos:":[42],"Levantamento":[43],"artigos":[45],"abordaram":[47],"estudos":[48],"PubMed,":[55],"Scielo,":[56],"Tandfoline,":[57],"Springer":[58],"link,":[59],"Scopus,":[60],"ScienceDirect,":[61],"e":[62,72,77,137,155],"demais":[63],"sites":[64],"busca":[66,147],"acad\u00eamica":[67],"sem":[68],"restri\u00e7\u00e3o":[69],"idioma":[71],"ano,":[73],"descritores":[76],"DeCS":[78],"(Descritores":[79],"em":[80,109],"Ci\u00eancias":[81],"Sa\u00fade).":[83],"Resultados:":[84],"Foram":[85],"128":[87],"estudos,":[88],"dos":[89],"quais":[90],"22":[91],"foram":[92],"selecionados":[93],"esta":[95],"revis\u00e3o.":[96],"Conclus\u00e3o:":[97],"O":[98],"caminho":[99],"a":[100],"ser":[101],"percorrido":[102],"\u00e9":[103],"longo,":[104],"at\u00e9":[105],"agora":[106],"sabemos":[108],"momento":[111],"um":[112],"novo":[113],"f\u00e1rmaco":[114],"chegara":[115],"auxiliar":[117],"no":[118,130],"tratamento":[119,152],"dessa":[120],"doen\u00e7a,":[121],"nesse":[122],"meio":[123],"tempo":[124],"v\u00e1rias":[125],"pesquisas":[126],"surgem":[127],"proposito":[129],"tratamento,":[131],"acess\u00edvel":[132],"Doen\u00e7a":[134],"Alzheimer":[136,154],"essa":[138],"pesquisa":[139],"servira":[140],"como":[141],"base":[142],"futuros":[144],"autores":[145],"marcadores":[149],"qu\u00edmicos":[150],"alimenticias.":[157]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-08-21T00:00:00"}