{"id":"https://openalex.org/W4292474151","doi":"https://doi.org/10.1016/j.jpsychires.2022.08.018","title":"Solriamfetol treatment of excessive daytime sleepiness in participants with narcolepsy or obstructive sleep apnea with a history of depression","display_name":"Solriamfetol treatment of excessive daytime sleepiness in participants with narcolepsy or obstructive sleep apnea with a history of depression","publication_year":2022,"publication_date":"2022-08-20","ids":{"openalex":"https://openalex.org/W4292474151","doi":"https://doi.org/10.1016/j.jpsychires.2022.08.018","pmid":"https://pubmed.ncbi.nlm.nih.gov/36070638","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9718635"},"language":"en","primary_location":{"id":"doi:10.1016/j.jpsychires.2022.08.018","doi":"https://doi.org/10.1016/j.jpsychires.2022.08.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpsychires.2022.08.018","pdf_url":"https://www.sciencedirect.com/science/article/pii/S002239562200471X/pdf","source":{"id":"https://openalex.org/S160879026","display_name":"Journal of Psychiatric Research","issn_l":"0022-3956","issn":["0022-3956","1879-1379"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Psychiatric Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S002239562200471X/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042168269","display_name":"Andrew D. Krystal","orcid":"https://orcid.org/0000-0002-6702-781X","observed_orcids":["https://orcid.org/0000-0002-6702-781X"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew D. Krystal","raw_affiliation_strings":["Psychiatry and Behavioral Science, University of California San Francisco, San Francisco, CA, USA. Electronic address: andrew.krystal@ucsf.edu","Psychiatry and Behavioral Science, University of California San Francisco, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry and Behavioral Science, University of California San Francisco, San Francisco, CA, USA. Electronic address: andrew.krystal@ucsf.edu","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Psychiatry and Behavioral Science, University of California San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049632383","display_name":"Ruth M. Benca","orcid":"https://orcid.org/0000-0002-5895-817X","observed_orcids":["https://orcid.org/0000-0002-5895-817X"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruth M. Benca","raw_affiliation_strings":["Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, USA","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082868877","display_name":"Russell P. Rosenberg","orcid":"https://orcid.org/0000-0002-6463-0082","observed_orcids":["https://orcid.org/0000-0002-6463-0082"]},"institutions":[{"id":"https://openalex.org/I4210149960","display_name":"NeuroTrials Research (United States)","ror":"https://ror.org/044jq0109","country_code":"US","type":"company","lineage":["https://openalex.org/I4210149960"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell Rosenberg","raw_affiliation_strings":["NeuroTrials Research Inc., Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NeuroTrials Research Inc., Atlanta, GA, USA","institution_ids":["https://openalex.org/I4210149960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066193017","display_name":"Paula Klingenberg Schweitzer","orcid":"https://orcid.org/0000-0001-6081-1620","observed_orcids":["https://orcid.org/0000-0001-6081-1620"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paula K. Schweitzer","raw_affiliation_strings":["Sleep Medicine and Research Center, St. Luke's Hospital, Chesterfield, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sleep Medicine and Research Center, St. Luke's Hospital, Chesterfield, MO, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047479450","display_name":"Atul Malhotra","orcid":"https://orcid.org/0000-0002-9509-1827","observed_orcids":["https://orcid.org/0000-0002-9509-1827"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Atul Malhotra","raw_affiliation_strings":["Division of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, La Jolla, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078683712","display_name":"Kimberly A. Babson","orcid":"https://orcid.org/0000-0002-9233-8230","observed_orcids":["https://orcid.org/0000-0002-9233-8230"]},"institutions":[{"id":"https://openalex.org/I4210101297","display_name":"Jazz Pharmaceuticals (United States)","ror":"https://ror.org/019rsbe67","country_code":"US","type":"company","lineage":["https://openalex.org/I4210101297","https://openalex.org/I4210152300"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly Babson","raw_affiliation_strings":["Jazz Pharmaceuticals, Palo Alto, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jazz Pharmaceuticals, Palo Alto, CA, USA","institution_ids":["https://openalex.org/I4210101297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100662312","display_name":"Lawrence Lee","orcid":"https://orcid.org/0000-0003-3990-2469","observed_orcids":["https://orcid.org/0000-0003-3990-2469"]},"institutions":[{"id":"https://openalex.org/I4210101297","display_name":"Jazz Pharmaceuticals (United States)","ror":"https://ror.org/019rsbe67","country_code":"US","type":"company","lineage":["https://openalex.org/I4210101297","https://openalex.org/I4210152300"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lawrence Lee","raw_affiliation_strings":["Jazz Pharmaceuticals, Palo Alto, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jazz Pharmaceuticals, Palo Alto, CA, USA","institution_ids":["https://openalex.org/I4210101297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048443892","display_name":"Shay Bujanover","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210101297","display_name":"Jazz Pharmaceuticals (United States)","ror":"https://ror.org/019rsbe67","country_code":"US","type":"company","lineage":["https://openalex.org/I4210101297","https://openalex.org/I4210152300"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shay Bujanover","raw_affiliation_strings":["Jazz Pharmaceuticals, Palo Alto, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jazz Pharmaceuticals, Palo Alto, CA, USA","institution_ids":["https://openalex.org/I4210101297"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037314029","display_name":"Kingman Perkins Strohl","orcid":"https://orcid.org/0000-0001-7740-9013","observed_orcids":["https://orcid.org/0000-0001-7740-9013"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kingman P. Strohl","raw_affiliation_strings":["Case Western Reserve University, Cleveland, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University, Cleveland, OH, USA","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5042168269"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":{"value":3170,"currency":"USD","value_usd":3170},"apc_paid":{"value":3170,"currency":"USD","value_usd":3170},"fwci":2.5783,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.90050843,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"155","issue":null,"first_page":"202","last_page":"210"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.5756999850273132,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.5756999850273132,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.16660000383853912,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.15489999949932098,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/solriamfetol","display_name":"solriamfetol","score":1.0},{"id":"https://openalex.org/keywords/excessive-daytime-sleepiness","display_name":"excessive daytime sleepiness","score":0.9919999837875366},{"id":"https://openalex.org/keywords/narcolepsy","display_name":"narcolepsy","score":0.996999979019165},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":1.0},{"id":"https://openalex.org/keywords/history-of-depression","display_name":"history of depression","score":0.7730000019073486},{"id":"https://openalex.org/keywords/wakefulness-promoting-agents","display_name":"wakefulness-promoting agents","score":0.7929999828338623},{"id":"https://openalex.org/keywords/sleep-disorders-comorbidity","display_name":"sleep disorders comorbidity","score":0.6940000057220459},{"id":"https://openalex.org/keywords/treatment-emergent-adverse-events","display_name":"treatment-emergent adverse events","score":0.8109999895095825},{"id":"https://openalex.org/keywords/sleep-onset-latency","display_name":"sleep latency","score":0.4959999918937683}],"concepts":[{"id":"https://openalex.org/C2779494582","wikidata":"https://www.wikidata.org/wiki/Q189561","display_name":"Narcolepsy","level":3,"score":0.860114574432373},{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.593300461769104},{"id":"https://openalex.org/C2778664715","wikidata":"https://www.wikidata.org/wiki/Q1347756","display_name":"Epworth Sleepiness Scale","level":4,"score":0.5897378325462341},{"id":"https://openalex.org/C2781433485","wikidata":"https://www.wikidata.org/wiki/Q3144201","display_name":"Excessive daytime sleepiness","level":4,"score":0.5664092302322388},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.5127121210098267},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5055272579193115},{"id":"https://openalex.org/C2779320081","wikidata":"https://www.wikidata.org/wiki/Q246710","display_name":"Wakefulness","level":3,"score":0.4970689117908478},{"id":"https://openalex.org/C2777446050","wikidata":"https://www.wikidata.org/wiki/Q1664214","display_name":"Multiple Sleep Latency Test","level":5,"score":0.4779415428638458},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.4667508900165558},{"id":"https://openalex.org/C2776571617","wikidata":"https://www.wikidata.org/wiki/Q2657784","display_name":"Atypical depression","level":3,"score":0.43868422508239746},{"id":"https://openalex.org/C2779034229","wikidata":"https://www.wikidata.org/wiki/Q1077823","display_name":"Somnolence","level":3,"score":0.4354827404022217},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4336455762386322},{"id":"https://openalex.org/C2780163352","wikidata":"https://www.wikidata.org/wiki/Q944473","display_name":"Cataplexy","level":4,"score":0.41301673650741577},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39825332164764404},{"id":"https://openalex.org/C1513209611","wikidata":"https://www.wikidata.org/wiki/Q177190","display_name":"Sleep disorder","level":3,"score":0.3859162926673889},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.3546930253505707},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.34353119134902954},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.3189893960952759},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.31483566761016846},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3063182830810547},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.300386518239975},{"id":"https://openalex.org/C2781210498","wikidata":"https://www.wikidata.org/wiki/Q1869874","display_name":"Insomnia","level":2,"score":0.2659931182861328},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.2598249316215515},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.24223417043685913},{"id":"https://openalex.org/C2780714222","wikidata":"https://www.wikidata.org/wiki/Q410441","display_name":"Modafinil","level":2,"score":0.23906975984573364},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002219","descriptor_name":"Carbamates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006970","descriptor_name":"Disorders of Excessive Somnolence","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006970","descriptor_name":"Disorders of Excessive Somnolence","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009290","descriptor_name":"Narcolepsy","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009290","descriptor_name":"Narcolepsy","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010649","descriptor_name":"Phenylalanine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jpsychires.2022.08.018","doi":"https://doi.org/10.1016/j.jpsychires.2022.08.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpsychires.2022.08.018","pdf_url":"https://www.sciencedirect.com/science/article/pii/S002239562200471X/pdf","source":{"id":"https://openalex.org/S160879026","display_name":"Journal of Psychiatric Research","issn_l":"0022-3956","issn":["0022-3956","1879-1379"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Psychiatric Research","raw_type":"journal-article"},{"id":"pmid:36070638","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36070638","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of psychiatric research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9718635","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9718635","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Psychiatr Res","raw_type":"Text"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt1zz2f4pj","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/1zz2f4pj","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Psychiatric Research, vol 155","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.jpsychires.2022.08.018","doi":"https://doi.org/10.1016/j.jpsychires.2022.08.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpsychires.2022.08.018","pdf_url":"https://www.sciencedirect.com/science/article/pii/S002239562200471X/pdf","source":{"id":"https://openalex.org/S160879026","display_name":"Journal of Psychiatric Research","issn_l":"0022-3956","issn":["0022-3956","1879-1379"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Psychiatric Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8199999928474426}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1911480146","display_name":"Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease","funder_award_id":"R01AG063925","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G272066749","display_name":"Underlying mechanisms of obesity-induced obstructive sleep apnea","funder_award_id":"R01HL148436","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2735123909","display_name":"Training in the Next Generation in Respiratory Science","funder_award_id":"T32HL134632","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G864476395","display_name":"Assessment of Upper Airway Mechanics Using Newer Electromyographic Techniques","funder_award_id":"K24HL132105","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000897733","display_name":"VentNet: A Real-Time Multimodal Data Integration Model for Prediction of Respiratory Failure in Patients with COVID-19","funder_award_id":"R01HL157985","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000911421","display_name":"Sleep Apnea Endophenotypes: One Size Does Not Fit All","funder_award_id":"R01HL154926","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320312570","display_name":"Jazz Pharmaceuticals","ror":"https://ror.org/055mhsv54"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4292474151.pdf","grobid_xml":"https://content.openalex.org/works/W4292474151.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W183461293","https://openalex.org/W197066864","https://openalex.org/W2011435303","https://openalex.org/W2065513803","https://openalex.org/W2115476973","https://openalex.org/W2148083007","https://openalex.org/W2471693769","https://openalex.org/W2528663061","https://openalex.org/W2610697518","https://openalex.org/W2742814779","https://openalex.org/W2905201451","https://openalex.org/W2912654414","https://openalex.org/W2914272431","https://openalex.org/W2914973997","https://openalex.org/W2924270878","https://openalex.org/W2998747560","https://openalex.org/W3043667968","https://openalex.org/W3090293687"],"related_works":["https://openalex.org/W2317343751","https://openalex.org/W4394976691","https://openalex.org/W3107028429","https://openalex.org/W3087983415","https://openalex.org/W3156322512","https://openalex.org/W2990506443","https://openalex.org/W4394978763","https://openalex.org/W3118629486","https://openalex.org/W4402724872","https://openalex.org/W2968238396"],"abstract_inverted_index":{"Given":[0],"the":[1,202,205],"high":[2,206],"rate":[3],"of":[4,18,21,31,89,113,120,153,186,208,220],"depression":[5,32,199,209],"associated":[6],"with":[7,73,78,212],"narcolepsy":[8,74,83,192],"or":[9,53,60],"obstructive":[10],"sleep":[11,94,138,213],"apnea":[12],"(OSA),":[13],"this":[14,221],"analysis":[15,36],"compared":[16],"effects":[17],"solriamfetol":[19,54,65,187],"treatment":[20],"excessive":[22],"daytime":[23],"sleepiness":[24],"(EDS)":[25],"in":[26,44,177,191,210],"participants":[27,46,114,154],"with/without":[28],"a":[29],"history":[30],"(DHx+/DHx-).":[33],"This":[34,179],"secondary":[35],"included":[37],"data":[38],"from":[39],"two":[40],"randomized,":[41],"controlled":[42],"trials":[43],"which":[45],"were":[47,80,175],"randomized":[48],"to":[49,129,164],"12":[50],"weeks":[51],"placebo":[52],"37.5":[55],"(OSA":[56],"only),":[57],"75,":[58],"150,":[59],"300":[61],"mg/day.":[62],"Efficacy/safety":[63],"(combined":[64],"doses)":[66],"was":[67,123,158],"summarized":[68],"for":[69,188],"DHx+/DHx-subgroups.":[70],"27.5%":[71],"(65/236)":[72],"and":[75,85,98,108,111,126,134,142,148,151,161,184,193,215],"23.4%":[76],"(111/474)":[77],"OSA":[79,132,194],"DHx+.":[81],"In":[82,131],"(DHx+":[84,133],"DHx-),":[86,135],"40-min":[87],"Maintenance":[88],"Wakefulness":[90],"Test":[91],"(MWT40)":[92],"mean":[93,137],"latency":[95,139],"increased":[96,140,218],"(5.4":[97],"7.0":[99],"min),":[100,144],"Epworth":[101],"Sleepiness":[102],"Scale":[103],"(ESS)":[104],"score":[105],"decreased":[106,146,171],"(3.8":[107],"3.5":[109],"points),":[110,150],"percentage":[112,152],"improved":[115,155],"on":[116,156],"Patient":[117],"Global":[118],"Impression":[119],"Change":[121],"(PGI-C)":[122],"higher":[124,159],"(31.7%":[125],"39.4%)":[127],"relative":[128,163],"placebo.":[130,165],"MWT40":[136],"(7.7":[141],"10.7":[143],"ESS":[145],"(3.5":[147],"3.7":[149],"PGI-C":[157],"(41.1%":[160],"29.4%)":[162],"Common":[166],"treatment-emergent":[167],"adverse":[168],"events":[169],"(headache,":[170],"appetite,":[172],"nausea,":[173],"anxiety)":[174],"similar":[176],"DHx+/DHx-.":[178],"study":[180],"suggests":[181],"that":[182,217],"safety":[183],"efficacy":[185],"treating":[189],"EDS":[190],"are":[195],"not":[196],"affected":[197],"by":[198],"history.":[200],"Moreover,":[201],"findings":[203],"emphasize":[204],"prevalence":[207],"people":[211],"disorders":[214],"suggest":[216],"awareness":[219],"association":[222],"may":[223],"have":[224],"clinical":[225],"significance.":[226]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-08-21T00:00:00"}