{"id":"https://openalex.org/W4292373070","doi":"https://doi.org/10.3389/fendo.2022.909317","title":"Vibration therapy as an effective approach to improve bone healing in diabetic rats","display_name":"Vibration therapy as an effective approach to improve bone healing in diabetic rats","publication_year":2022,"publication_date":"2022-08-19","ids":{"openalex":"https://openalex.org/W4292373070","doi":"https://doi.org/10.3389/fendo.2022.909317","pmid":"https://pubmed.ncbi.nlm.nih.gov/36060973","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9437439"},"language":"en","primary_location":{"id":"doi:10.3389/fendo.2022.909317","doi":"https://doi.org/10.3389/fendo.2022.909317","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2022.909317","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2022.909317/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fendo.2022.909317/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015095424","display_name":"Maysa S. Campos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Maysa S. Campos","raw_affiliation_strings":["Department of Orthopaedics and Anaesthesiology, Ribeir\u00e3o Preto Medical School, University of Sao Paulo, Ribeir\u00e3o Preto, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Anaesthesiology, Ribeir\u00e3o Preto Medical School, University of Sao Paulo, Ribeir\u00e3o Preto, SP, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102774262","display_name":"Jos\u00e9 Batista Volpon","orcid":"https://orcid.org/0000-0002-1999-7352","observed_orcids":["https://orcid.org/0000-0002-1999-7352"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 B. Volpon","raw_affiliation_strings":["Department of Orthopaedics and Anaesthesiology, Ribeir\u00e3o Preto Medical School, University of Sao Paulo, Ribeir\u00e3o Preto, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Anaesthesiology, Ribeir\u00e3o Preto Medical School, University of Sao Paulo, Ribeir\u00e3o Preto, SP, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011428149","display_name":"Jo\u00e3o Paulo Bianchi Ximenez","orcid":"https://orcid.org/0000-0002-6414-5220","observed_orcids":["https://orcid.org/0000-0002-6414-5220"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210156537","display_name":"Clinics Hospital of Ribeir\u00e3o Preto","ror":"https://ror.org/04n6fhj26","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I17974374","https://openalex.org/I4210156537"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jo\u00e3o Paulo B. Ximenez","raw_affiliation_strings":["Laboratory of Molecular Biology, Blood Center of Ribeir\u00e3o Preto, Ribeir\u00e3o Preto Medical School, Ribeir\u00e3o Preto, SP, Brazil","School of Pharmaceutical Sciences of Ribeir\u00e3o Preto - University of S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Biology, Blood Center of Ribeir\u00e3o Preto, Ribeir\u00e3o Preto Medical School, Ribeir\u00e3o Preto, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210156537"]},{"raw_affiliation_string":"School of Pharmaceutical Sciences of Ribeir\u00e3o Preto - University of S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035856470","display_name":"Ana Paula Franttini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ana Paula Franttini","raw_affiliation_strings":["Department of Orthopaedics and Anaesthesiology, Ribeir\u00e3o Preto Medical School, University of Sao Paulo, Ribeir\u00e3o Preto, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Anaesthesiology, Ribeir\u00e3o Preto Medical School, University of Sao Paulo, Ribeir\u00e3o Preto, SP, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010429242","display_name":"Christopher E. Dalloul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher E. Dalloul","raw_affiliation_strings":["Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035854272","display_name":"Manoel Dami\u00e3o Sousa\u2010Neto","orcid":"https://orcid.org/0000-0002-7696-7600","observed_orcids":["https://orcid.org/0000-0002-7696-7600"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Manoel D. Sousa-Neto","raw_affiliation_strings":["School of Dentistry of Ribeir\u00e3o Preto - University of S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Dentistry of Ribeir\u00e3o Preto - University of S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Raquel A. Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Raquel A. Silva","raw_affiliation_strings":["School of Dentistry of Ribeir\u00e3o Preto - University of S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Dentistry of Ribeir\u00e3o Preto - University of S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034416233","display_name":"Melissa A. Kacena","orcid":"https://orcid.org/0000-0001-7293-0088","observed_orcids":["https://orcid.org/0000-0001-7293-0088"]},"institutions":[{"id":"https://openalex.org/I4210110049","display_name":"Richard L. Roudebush VA Medical Center","ror":"https://ror.org/01zpmbk67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210110049","https://openalex.org/I4210127612","https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa A. Kacena","raw_affiliation_strings":["Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States","Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States","institution_ids":["https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN, United States","institution_ids":["https://openalex.org/I4210110049"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016940971","display_name":"Ariane Zamarioli","orcid":"https://orcid.org/0000-0002-7939-0528","observed_orcids":["https://orcid.org/0000-0002-7939-0528"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Ariane Zamarioli","raw_affiliation_strings":["Department of Orthopaedics and Anaesthesiology, Ribeir\u00e3o Preto Medical School, University of Sao Paulo, Ribeir\u00e3o Preto, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Anaesthesiology, Ribeir\u00e3o Preto Medical School, University of Sao Paulo, Ribeir\u00e3o Preto, SP, Brazil","institution_ids":["https://openalex.org/I17974374"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5016940971"],"corresponding_institution_ids":["https://openalex.org/I17974374"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":1.859,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.82196583,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"13","issue":null,"first_page":"909317","last_page":"909317"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12269","display_name":"Effects of Vibration on Health","score":0.7515000104904175,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12269","display_name":"Effects of Vibration on Health","score":0.7515000104904175,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10658","display_name":"Bone fractures and treatments","score":0.19699999690055847,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.037300001829862595,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vibration-therapy","display_name":"vibration therapy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/fracture-healing","display_name":"fracture healing","score":0.8690000176429749},{"id":"https://openalex.org/keywords/diabetic-bone-healing","display_name":"diabetic bone healing","score":0.6740000247955322},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.7350000143051147},{"id":"https://openalex.org/keywords/osteogenic-differentiation","display_name":"osteogenic differentiation","score":0.6150000095367432},{"id":"https://openalex.org/keywords/chondrogenic-differentiation","display_name":"chondrogenic differentiation","score":0.9319999814033508},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.9120000004768372},{"id":"https://openalex.org/keywords/rankl","display_name":"RANKL","score":0.8939999938011169},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.7160000205039978},{"id":"https://openalex.org/keywords/bone-callus","display_name":"bone callus","score":0.6480000019073486},{"id":"https://openalex.org/keywords/osteoclastogenesis","display_name":"osteoclastogenesis","score":0.47099998593330383},{"id":"https://openalex.org/keywords/mechanical-stimulation","display_name":"mechanical stimulation","score":0.6269999742507935},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.8429999947547913},{"id":"https://openalex.org/keywords/osteoblast-gene-expression","display_name":"osteoblast gene expression","score":0.6779999732971191},{"id":"https://openalex.org/keywords/trabecular-bone-microarchitecture","display_name":"trabecular bone microarchitecture","score":0.7009999752044678},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.375}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7317429780960083},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.7020602822303772},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.666923999786377},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6401210427284241},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5748376846313477},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.5675700902938843},{"id":"https://openalex.org/C673006","wikidata":"https://www.wikidata.org/wiki/Q4941581","display_name":"Bone resorption","level":2,"score":0.5200602412223816},{"id":"https://openalex.org/C2778260815","wikidata":"https://www.wikidata.org/wiki/Q917177","display_name":"Osteoblast","level":3,"score":0.49263817071914673},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.47729504108428955},{"id":"https://openalex.org/C125870589","wikidata":"https://www.wikidata.org/wiki/Q16959485","display_name":"N-terminal telopeptide","level":5,"score":0.43459394574165344},{"id":"https://openalex.org/C2779329777","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone density","level":3,"score":0.41665852069854736},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.31009384989738464},{"id":"https://openalex.org/C131075544","wikidata":"https://www.wikidata.org/wiki/Q415863","display_name":"Osteocalcin","level":4,"score":0.2439587414264679},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.20378920435905457},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15136581659317017},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.09161192178726196},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002146","descriptor_name":"Bony Callus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002146","descriptor_name":"Bony Callus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D007334","descriptor_name":"Insulin-Like Growth Factor I","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014732","descriptor_name":"Vibration","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017102","descriptor_name":"Fracture Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3389/fendo.2022.909317","doi":"https://doi.org/10.3389/fendo.2022.909317","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2022.909317","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2022.909317/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},{"id":"pmid:36060973","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36060973","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9437439","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9437439/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Endocrinol (Lausanne)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:0b7d9155cd3546a297b2930af17d4900","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/0b7d9155cd3546a297b2930af17d4900","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Endocrinology, Vol 13 (2022)","raw_type":"article"},{"id":"pmh:oai:scholarworks.indianapolis.iu.edu:1805/35341","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1805/35341","pdf_url":null,"source":{"id":"https://openalex.org/S4306400987","display_name":"IUScholarWorks (Indiana University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I592451","host_organization_name":"Indiana University","host_organization_lineage":["https://openalex.org/I592451"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PMC","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.3389/fendo.2022.909317","doi":"https://doi.org/10.3389/fendo.2022.909317","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2022.909317","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2022.909317/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4357132100","display_name":null,"funder_award_id":"I01 BX003751","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G4602881204","display_name":null,"funder_award_id":"IK6 RX004809","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G5520316217","display_name":null,"funder_award_id":"NIH-R01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8332614402","display_name":"Angiogenic Therapy: Novel Approaches to Enhance Bone Regeneration in Aging","funder_award_id":"R01AG060621","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4292373070.pdf","grobid_xml":"https://content.openalex.org/works/W4292373070.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1544054914","https://openalex.org/W1570680667","https://openalex.org/W1972206562","https://openalex.org/W1975421186","https://openalex.org/W1984498521","https://openalex.org/W1995605428","https://openalex.org/W2009497906","https://openalex.org/W2013785685","https://openalex.org/W2013987973","https://openalex.org/W2016394110","https://openalex.org/W2022798444","https://openalex.org/W2036263733","https://openalex.org/W2049324965","https://openalex.org/W2058261270","https://openalex.org/W2075647457","https://openalex.org/W2084103054","https://openalex.org/W2087619473","https://openalex.org/W2097059082","https://openalex.org/W2097283220","https://openalex.org/W2115242381","https://openalex.org/W2120906476","https://openalex.org/W2126052469","https://openalex.org/W2130143727","https://openalex.org/W2131026912","https://openalex.org/W2133438668","https://openalex.org/W2133584055","https://openalex.org/W2133882030","https://openalex.org/W2143584579","https://openalex.org/W2153151468","https://openalex.org/W2170574458","https://openalex.org/W2280269944","https://openalex.org/W2345822173","https://openalex.org/W2398549144","https://openalex.org/W2411490512","https://openalex.org/W2560399367","https://openalex.org/W2752206022","https://openalex.org/W2973958770","https://openalex.org/W3014961299","https://openalex.org/W3112726207","https://openalex.org/W3195297576"],"related_works":["https://openalex.org/W2596082853","https://openalex.org/W2381854334","https://openalex.org/W1966166128","https://openalex.org/W2367439915","https://openalex.org/W2384469631","https://openalex.org/W2116663468","https://openalex.org/W2316023665","https://openalex.org/W4311478171","https://openalex.org/W2763189076","https://openalex.org/W2337199987"],"abstract_inverted_index":{"Objective":[0],"To":[1],"investigate":[2],"the":[3,174,197,212,243,301,335],"effects":[4,291],"of":[5,119,176,230,280,338],"vibration":[6,39],"therapy":[7,40,296],"on":[8,81,110,292],"fracture":[9,20,244,314,352],"healing":[10,78,121,315],"in":[11,128,134,145,151,157,162,173,188,204,211,218,225,246,276,304,316,354],"diabetic":[12,44,49,205,247,355],"and":[13,22,46,84,92,102,132,160,221,238,264,269,329,340,345],"non-diabetic":[14,31,35,140,317],"rats.":[15,319,356],"Methods":[16],"148":[17],"rats":[18,36,50,74,142],"underwent":[19,62],"surgery":[21],"were":[23,167,202],"assigned":[24],"to":[25,115,139],"four":[26],"groups:":[27],"(1)":[28],"SHAM:":[29],"weight-matched":[30],"rats,":[32,45,206],"(2)":[33],"SHAM+VT:":[34],"treated":[37,51],"with":[38,52,59,272],"(VT),":[41],"(3)":[42],"DM:":[43],"(4)":[47],"DM+VT:":[48],"VT.":[53,76],"Thirty":[54],"days":[55,70,82],"after":[56,71],"diabetes":[57],"induction":[58],"streptozotocin,":[60],"animals":[61],"bone":[63,72,89,120,129,146,153,259,293,305,326,343],"fracture,":[64,73],"followed":[65],"by":[66,87,124,169,252,256,262,267,308],"surgical":[67],"stabilization.":[68],"Three":[69],"began":[75],"Bone":[77],"was":[79,270,297],"assessed":[80],"14":[83],"28":[85],"post-fracture":[86],"serum":[88,189,226,336],"marker":[90],"analysis,":[91],"femurs":[93],"collected":[94],"for":[95,350],"dual-energy":[96],"X-ray":[97],"absorptiometry,":[98],"micro-computed":[99],"tomography,":[100],"histology,":[101],"gene":[103],"expression.":[104],"Results":[105],"Our":[106],"results":[107],"are":[108],"based":[109],"88":[111],"animals.":[112],"Diabetes":[113,288],"led":[114],"a":[116,125,170,185,208,215,222,273],"dramatic":[117],"impairment":[118],"as":[122,182,184],"demonstrated":[123],"17%":[126],"reduction":[127,144,150,156,187,275],"mineral":[130,260],"density":[131],"decreases":[133],"formation-related":[135],"microstructural":[136],"parameters":[137,201],"compared":[138],"control":[141,318],"(81%":[143],"callus":[147,213,245,254,258,265,327],"volume,":[148],"69%":[149],"woven":[152],"fraction,":[154],"39%":[155],"trabecular":[158,163,219],"thickness,":[159],"45%":[161],"number).":[164],"These":[165],"changes":[166],"accompanied":[168],"significant":[171,302],"decrease":[172],"expression":[175],"osteoblast-related":[177],"genes":[178],"(Runx2,":[179],"Col1a1,":[180],"Osx),":[181],"well":[183],"92%":[186],"insulin-like":[190],"growth":[191],"factor":[192,282],"I":[193],"(IGF-1)":[194],"levels.":[195,234],"On":[196],"other":[198],"hand,":[199],"resorption-related":[200],"increased":[203,249],"including":[207],"20%":[209],"increase":[210,217,224],"porosity,":[214],"33%":[216],"separation,":[220],"318%":[223],"C":[227],"terminal":[228],"telopeptide":[229],"type":[231],"1":[232],"collagen":[233],"VT":[235],"augmented":[236],"osteogenic":[237],"chondrogenic":[239],"cell":[240],"proliferation":[241],"at":[242,299],"rats;":[248],"circulating":[250,277],"IGF-1":[251,339],"668%,":[253],"volume":[255],"52%,":[257],"content":[261],"90%,":[263],"area":[266],"72%;":[268],"associated":[271],"19%":[274],"receptor":[278],"activator":[279],"nuclear":[281],"kappa":[283],"beta":[284],"ligand":[285],"(RANK-L).":[286],"Conclusions":[287],"had":[289],"detrimental":[290],"healing.":[294],"Vibration":[295],"effective":[298],"counteracting":[300],"disruption":[303],"repair":[306,353],"induced":[307],"diabetes,":[309],"but":[310,331],"did":[311],"not":[312,323],"improve":[313],"The":[320],"mechanical":[321],"stimulus":[322],"only":[324],"improved":[325],"quality":[328],"quantity,":[330],"also":[332],"partially":[333],"restored":[334],"levels":[337],"RANK-L,":[341],"inducing":[342],"formation":[344],"mineralization,":[346],"thus":[347],"creating":[348],"conditions":[349],"adequate":[351]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-08-20T00:00:00"}