{"id":"https://openalex.org/W4292065397","doi":"https://doi.org/10.1073/pnas.2204167119","title":"Identification of basal complex protein that is essential for maturation of transmission-stage malaria parasites","display_name":"Identification of basal complex protein that is essential for maturation of transmission-stage malaria parasites","publication_year":2022,"publication_date":"2022-08-16","ids":{"openalex":"https://openalex.org/W4292065397","doi":"https://doi.org/10.1073/pnas.2204167119","pmid":"https://pubmed.ncbi.nlm.nih.gov/35972967","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9407223"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.2204167119","doi":"https://doi.org/10.1073/pnas.2204167119","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.2204167119","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1073/pnas.2204167119","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061451265","display_name":"Rebecca L. Clements","orcid":"https://orcid.org/0000-0001-9726-1554","observed_orcids":["https://orcid.org/0000-0001-9726-1554"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca L. Clements","raw_affiliation_strings":["Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115","Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115"],"raw_orcid":"https://orcid.org/0000-0001-9726-1554","affiliations":[{"raw_affiliation_string":"Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039730097","display_name":"Alexander A. Morano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander A. Morano","raw_affiliation_strings":["Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115","Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078441393","display_name":"Francesca M. Navarro","orcid":"https://orcid.org/0000-0001-6654-2775","observed_orcids":["https://orcid.org/0000-0001-6654-2775"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francesca M. Navarro","raw_affiliation_strings":["Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115","Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044981543","display_name":"James P. McGee","orcid":"https://orcid.org/0000-0003-0225-1172","observed_orcids":["https://orcid.org/0000-0003-0225-1172"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James P. McGee","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, the Huck Center for Malaria Research, Pennsylvania State University, University Park, PA 16802","Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115"],"raw_orcid":"https://orcid.org/0000-0003-0225-1172","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, the Huck Center for Malaria Research, Pennsylvania State University, University Park, PA 16802","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102840090","display_name":"Esrah W. Du","orcid":"https://orcid.org/0000-0002-4553-5442","observed_orcids":["https://orcid.org/0000-0002-4553-5442"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Esrah W. Du","raw_affiliation_strings":["Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037074592","display_name":"Vincent A. Streva","orcid":"https://orcid.org/0009-0004-6306-7517","observed_orcids":["https://orcid.org/0009-0004-6306-7517"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vincent A. Streva","raw_affiliation_strings":["Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009057593","display_name":"Scott E. Lindner","orcid":"https://orcid.org/0000-0003-1799-3726","observed_orcids":["https://orcid.org/0000-0003-1799-3726"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott E. Lindner","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, the Huck Center for Malaria Research, Pennsylvania State University, University Park, PA 16802"],"raw_orcid":"https://orcid.org/0000-0003-1799-3726","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, the Huck Center for Malaria Research, Pennsylvania State University, University Park, PA 16802","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015004890","display_name":"Jeffrey D. Dvorin","orcid":"https://orcid.org/0000-0002-5883-7271","observed_orcids":["https://orcid.org/0000-0002-5883-7271"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jeffrey D. Dvorin","raw_affiliation_strings":["Department of Pediatrics, Harvard Medical School, Boston, MA 02115","Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115"],"raw_orcid":"https://orcid.org/0000-0002-5883-7271","affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Harvard Medical School, Boston, MA 02115","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, MA 02115","institution_ids":["https://openalex.org/I1288882113"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015004890"],"corresponding_institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984"],"apc_list":null,"apc_paid":null,"fwci":2.2046,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.86103441,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"119","issue":"34","first_page":"e2204167119","last_page":"e2204167119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11155","display_name":"Toxoplasma gondii Research Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/basal-complex","display_name":"basal complex","score":0.9629999995231628},{"id":"https://openalex.org/keywords/inner-membrane-complex","display_name":"inner membrane complex","score":0.9620000123977661},{"id":"https://openalex.org/keywords/gametocytogenesis","display_name":"gametocytogenesis","score":0.9390000104904175},{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.9670000076293945},{"id":"https://openalex.org/keywords/gametocyte-maturation","display_name":"gametocyte maturation","score":0.8579999804496765},{"id":"https://openalex.org/keywords/asexual-replication","display_name":"asexual replication","score":0.6290000081062317},{"id":"https://openalex.org/keywords/antimalarial-drug-targets","display_name":"antimalarial drug targets","score":0.6269999742507935},{"id":"https://openalex.org/keywords/malaria-transmission","display_name":"malaria transmission","score":0.777999997138977}],"concepts":[{"id":"https://openalex.org/C99389464","wikidata":"https://www.wikidata.org/wiki/Q3319949","display_name":"Gametocyte","level":4,"score":0.9236422777175903},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8404067754745483},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.7407655715942383},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.696677029132843},{"id":"https://openalex.org/C2778675580","wikidata":"https://www.wikidata.org/wiki/Q614956","display_name":"Plasmodium (life cycle)","level":3,"score":0.6246511340141296},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5490449666976929},{"id":"https://openalex.org/C71928629","wikidata":"https://www.wikidata.org/wiki/Q804206","display_name":"Parasite hosting","level":2,"score":0.5489544868469238},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.49070560932159424},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.4735906720161438},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.4615144729614258},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.4266495704650879},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.37132275104522705},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.36130911111831665},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.35705965757369995},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.24207159876823425},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.1824532449245453},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1779392957687378},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000962","descriptor_name":"Antimalarials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005718","descriptor_name":"Gametogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1073/pnas.2204167119","doi":"https://doi.org/10.1073/pnas.2204167119","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.2204167119","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9407223","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9407223/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9407223/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:35972967","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35972967","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1073/pnas.2204167119","doi":"https://doi.org/10.1073/pnas.2204167119","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.2204167119","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4043000042438507}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2793857255","display_name":"Pediatric Infectious Diseases Research Training","funder_award_id":"T32HD055148","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G681720072","display_name":"Molecular mechanisms of schizogony in malaria parasites","funder_award_id":"R01AI145941","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000892059","display_name":"Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasites","funder_award_id":"R01AI169648","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4292065397.pdf","grobid_xml":"https://content.openalex.org/works/W4292065397.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W59987781","https://openalex.org/W1576714964","https://openalex.org/W1771852563","https://openalex.org/W1925767399","https://openalex.org/W1965646962","https://openalex.org/W1974078141","https://openalex.org/W1976112747","https://openalex.org/W1977027195","https://openalex.org/W1977332101","https://openalex.org/W1997960416","https://openalex.org/W2002279886","https://openalex.org/W2005020318","https://openalex.org/W2048671997","https://openalex.org/W2053558413","https://openalex.org/W2070893008","https://openalex.org/W2082460216","https://openalex.org/W2083280521","https://openalex.org/W2101144468","https://openalex.org/W2120482401","https://openalex.org/W2122914905","https://openalex.org/W2145657197","https://openalex.org/W2148507499","https://openalex.org/W2154248614","https://openalex.org/W2163672006","https://openalex.org/W2164862526","https://openalex.org/W2166854800","https://openalex.org/W2171323885","https://openalex.org/W2272441115","https://openalex.org/W2309402941","https://openalex.org/W2320132985","https://openalex.org/W2343077786","https://openalex.org/W2429903483","https://openalex.org/W2464796725","https://openalex.org/W2538382920","https://openalex.org/W2550548876","https://openalex.org/W2596280611","https://openalex.org/W2761314025","https://openalex.org/W2768045943","https://openalex.org/W2800834635","https://openalex.org/W2888567975","https://openalex.org/W2888618670","https://openalex.org/W2914349013","https://openalex.org/W2939922294","https://openalex.org/W2946313817","https://openalex.org/W3033382082","https://openalex.org/W3108206865","https://openalex.org/W3141243964","https://openalex.org/W4200122798"],"related_works":["https://openalex.org/W7130321147","https://openalex.org/W4404638252","https://openalex.org/W2761314025","https://openalex.org/W2309402941","https://openalex.org/W4407207381","https://openalex.org/W2343077786","https://openalex.org/W6908869339","https://openalex.org/W4306944143","https://openalex.org/W2166854800","https://openalex.org/W1553217956"],"abstract_inverted_index":{",":[0],"the":[1,5,16,22,44,47,68,121],"parasite":[2,23],"responsible":[3],"for":[4,82,104,120],"deadliest":[6],"cases":[7],"of":[8,29,37,46,70,110,123],"malaria.":[9],"A":[10],"membranous":[11],"and":[12,35,51,92],"proteinaceous":[13],"scaffold":[14],"called":[15],"inner":[17],"membrane":[18],"complex":[19,42,73,107],"(IMC)":[20],"supports":[21],"during":[24,32,49,64],"morphological":[25],"changes,":[26],"including":[27],"segmentation":[28,50],"daughter":[30],"cells":[31],"asexual":[33,111],"replication":[34],"formation":[36],"transmission-stage":[38],"gametocytes.":[39,98],"The":[40],"basal":[41,72,106],"lines":[43],"edge":[45],"IMC":[48,54,62,90],"likely":[52],"facilitates":[53],"expansion.":[55],"It":[56],"is":[57],"unknown,":[58],"however,":[59],"what":[60],"drives":[61],"expansion":[63,91],"gametocytogenesis.":[65,83],"We":[66],"describe":[67],"discovery":[69],"a":[71,102,105,116],"protein,":[74],"PfBLEB,":[75],"which":[76],"we":[77],"find":[78],"to":[79,95],"be":[80],"essential":[81],"Parasites":[84],"lacking":[85],"PfBLEB":[86],"harbor":[87],"defects":[88],"in":[89],"are":[93],"unable":[94],"form":[96],"mature":[97],"This":[99],"article":[100],"demonstrates":[101],"role":[103],"protein":[108],"outside":[109],"division,":[112],"and,":[113],"importantly,":[114],"highlights":[115],"potential":[117],"molecular":[118],"target":[119],"ablation":[122],"malaria":[124],"transmission.":[125]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2022-08-17T00:00:00"}