{"id":"https://openalex.org/W4291001262","doi":"https://doi.org/10.1097/00005176-198905000-00004","title":"Crohn\u02bcs Disease Lesions in the Upper Gastrointestinal Tract","display_name":"Crohn\u02bcs Disease Lesions in the Upper Gastrointestinal Tract","publication_year":1989,"publication_date":"1989-05-01","ids":{"openalex":"https://openalex.org/W4291001262","doi":"https://doi.org/10.1097/00005176-198905000-00004","mag":"2066032418","pmid":"https://pubmed.ncbi.nlm.nih.gov/2723935"},"language":"en","primary_location":{"id":"doi:10.1097/00005176-198905000-00004","doi":"https://doi.org/10.1097/00005176-198905000-00004","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00005176-198905000-00004","pdf_url":null,"source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047174577","display_name":"Mamba Nyenya L\u00e9onard Mashako","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126712","display_name":"H\u00f4pital Robert-Debr\u00e9","ror":"https://ror.org/02dcqy320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210126712"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Mamba Nyenya L\u00e9onard Mashako","raw_affiliation_strings":["Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France","institution_ids":["https://openalex.org/I4210126712"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111952222","display_name":"Jean Pierre Cezard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126712","display_name":"H\u00f4pital Robert-Debr\u00e9","ror":"https://ror.org/02dcqy320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210126712"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Jean Pierre Cezard","raw_affiliation_strings":["Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France","institution_ids":["https://openalex.org/I4210126712"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012710657","display_name":"J Navarro","orcid":"https://orcid.org/0009-0006-7333-9023","observed_orcids":["https://orcid.org/0009-0006-7333-9023"]},"institutions":[{"id":"https://openalex.org/I4210126712","display_name":"H\u00f4pital Robert-Debr\u00e9","ror":"https://ror.org/02dcqy320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210126712"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Jean Navarro","raw_affiliation_strings":["Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France","institution_ids":["https://openalex.org/I4210126712"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113088180","display_name":"J. F. Mougenot","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126712","display_name":"H\u00f4pital Robert-Debr\u00e9","ror":"https://ror.org/02dcqy320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210126712"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Jean Francois Mougenot","raw_affiliation_strings":["Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France","institution_ids":["https://openalex.org/I4210126712"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087489111","display_name":"Elise Sonsino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126712","display_name":"H\u00f4pital Robert-Debr\u00e9","ror":"https://ror.org/02dcqy320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210126712"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Elise Sonsino","raw_affiliation_strings":["Service d'Anatomic Pathologic, H\u00f4pital Robert Debre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service d'Anatomic Pathologic, H\u00f4pital Robert Debre, Paris, France","institution_ids":["https://openalex.org/I4210126712"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103872554","display_name":"Abdellatif Gargouri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126712","display_name":"H\u00f4pital Robert-Debr\u00e9","ror":"https://ror.org/02dcqy320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210126712"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Abdellatif Gargouri","raw_affiliation_strings":["Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France","institution_ids":["https://openalex.org/I4210126712"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073030546","display_name":"Ahmed Maherzi","orcid":"https://orcid.org/0000-0003-0959-1903","observed_orcids":["https://orcid.org/0000-0003-0959-1903"]},"institutions":[{"id":"https://openalex.org/I4210126712","display_name":"H\u00f4pital Robert-Debr\u00e9","ror":"https://ror.org/02dcqy320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210126712"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Ahmed Maherzi","raw_affiliation_strings":["Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Gastro-enterologie et Nutrition, H\u00f4pital Robert Debre, Paris, France","institution_ids":["https://openalex.org/I4210126712"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5012710657","https://openalex.org/A5047174577","https://openalex.org/A5073030546","https://openalex.org/A5103872554","https://openalex.org/A5111952222","https://openalex.org/A5113088180"],"corresponding_institution_ids":["https://openalex.org/I4210126712"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":2.2812,"has_fulltext":false,"cited_by_count":127,"citation_normalized_percentile":{"value":0.86395439,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"8","issue":"4","first_page":"442","last_page":"446"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11855","display_name":"Gastrointestinal disorders and treatments","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12578","display_name":"Diagnosis and treatment of tuberculosis","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":1.0},{"id":"https://openalex.org/keywords/upper-gastrointestinal-tract-involvement","display_name":"upper gastrointestinal tract involvement","score":0.8820000290870667},{"id":"https://openalex.org/keywords/pediatric-crohn-s-disease","display_name":"pediatric Crohn's disease","score":0.9100000262260437},{"id":"https://openalex.org/keywords/granuloma","display_name":"granuloma","score":0.7889999747276306},{"id":"https://openalex.org/keywords/multiple-biopsies","display_name":"multiple biopsies","score":0.8389999866485596},{"id":"https://openalex.org/keywords/endoscopic-diagnosis","display_name":"endoscopic diagnosis","score":0.6669999957084656},{"id":"https://openalex.org/keywords/histopathological-diagnosis","display_name":"histopathological diagnosis","score":0.6150000095367432},{"id":"https://openalex.org/keywords/underdiagnosis","display_name":"underdiagnosis","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9579406976699829},{"id":"https://openalex.org/C2778451229","wikidata":"https://www.wikidata.org/wiki/Q212809","display_name":"Endoscopy","level":2,"score":0.7051725387573242},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5978862643241882},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5762138962745667},{"id":"https://openalex.org/C2780512811","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Gastrointestinal tract","level":2,"score":0.5515093207359314},{"id":"https://openalex.org/C2779280984","wikidata":"https://www.wikidata.org/wiki/Q1472","display_name":"Crohn's disease","level":3,"score":0.5183787941932678},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5113193988800049},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.48414167761802673},{"id":"https://openalex.org/C190892606","wikidata":"https://www.wikidata.org/wiki/Q3512464","display_name":"Radiological weapon","level":2,"score":0.47118595242500305},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44710618257522583},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3533138036727905},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3038390874862671},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003424","descriptor_name":"Crohn Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003424","descriptor_name":"Crohn Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004386","descriptor_name":"Duodenum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004724","descriptor_name":"Endoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004947","descriptor_name":"Esophagus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1097/00005176-198905000-00004","doi":"https://doi.org/10.1097/00005176-198905000-00004","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00005176-198905000-00004","pdf_url":null,"source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},{"id":"pmid:2723935","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2723935","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric gastroenterology and nutrition","raw_type":"Journal Article"},{"id":"mag:2066032418","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2723935","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4390566590","https://openalex.org/W2066032418","https://openalex.org/W1964626998","https://openalex.org/W1725062471","https://openalex.org/W2011488850","https://openalex.org/W2003967398","https://openalex.org/W2000141137","https://openalex.org/W2077922141","https://openalex.org/W2047967434","https://openalex.org/W2781555507"],"abstract_inverted_index":{"The":[0],"incidence":[1],"of":[2,13,27,31,57,90,102,107,119,149,154,159,165,167,178,197,208],"Crohn's":[3,33],"disease":[4,34],"(CD)":[5],"lesions":[6,76],"in":[7,64,70,77,84,147,157,194,202],"the":[8,94,103,108,122,127,134,155,168,195,206,209],"upper":[9,40,58,169],"gastrointestinal":[10],"(GI)":[11],"tract":[12,42,60,171,186],"both":[14],"adults":[15],"and":[16,81,115,126,137,151,162,200],"children":[17,29,66,79,86,110],"is":[18,172],"frequently":[19],"underestimated.":[20],"In":[21,88],"this":[22,198],"prospective":[23],"study,":[24],"a":[25,144,152],"total":[26],"31":[28,109],"suspected":[30],"having":[32],"were":[35,62,96],"systematically":[36],"examined":[37],"to":[38],"identify":[39],"digestive":[41],"lesions.":[43],"They":[44],"all":[45],"underwent":[46],"barium":[47],"transit":[48],"endoscopy":[49,187],"with":[50,188],"multiple-level":[51],"biopsies.":[52],"Typical":[53],"clinical":[54,179],"symptoms":[55,180],"suggestive":[56,118],"GI":[59,170,185],"involvement":[61],"found":[63],"5":[65],"(16%),":[67],"radiological":[68,114,182],"signs":[69],"only":[71],"one":[72],"child":[73],"(3%),":[74],"endoscopic":[75,116],"13":[78],"(42%),":[80],"specific":[82],"granulomas":[83],"12":[85,92],"(39%).":[87],"eight":[89],"these":[91],"children,":[93],"biopsies":[95,190],"taken":[97],"from":[98],"macroscopically":[99],"normal":[100],"areas":[101],"esophagogastroduodenal":[104],"mucosa.":[105],"One":[106],"had":[111],"no":[112,131],"abnormal":[113],"features":[117],"CD":[120,166],"on":[121],"distal":[123],"small":[124],"bowel":[125],"colon.":[128],"There":[129],"was":[130],"correlation":[132],"between":[133],"clinical,":[135],"radiological,":[136],"histological":[138,163],"data.":[139],"Endoscopy":[140],"plus":[141],"biopsy":[142],"provided":[143],"positive":[145],"diagnosis":[146,156],"39%":[148],"cases":[150,204],"confirmation":[153],"87%":[158],"cases.":[160],"Endoscopic":[161],"evidence":[164],"often":[173],"present":[174],"despite":[175],"an":[176],"absence":[177],"or":[181],"changes.":[183],"Upper":[184],"multiple":[189],"may":[191],"be":[192],"important":[193],"evaluation":[196],"condition":[199],"even":[201],"some":[203],"for":[205],"establishment":[207],"diagnosis.":[210]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-08-13T00:00:00"}