{"id":"https://openalex.org/W4290861330","doi":"https://doi.org/10.1099/mgen.0.000858","title":"Shooting hoops: globetrotting plasmids spreading more than just antimicrobial resistance genes across One Health","display_name":"Shooting hoops: globetrotting plasmids spreading more than just antimicrobial resistance genes across One Health","publication_year":2022,"publication_date":"2022-08-12","ids":{"openalex":"https://openalex.org/W4290861330","doi":"https://doi.org/10.1099/mgen.0.000858","pmid":"https://pubmed.ncbi.nlm.nih.gov/35960657","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9484753"},"language":"en","primary_location":{"id":"doi:10.1099/mgen.0.000858","doi":"https://doi.org/10.1099/mgen.0.000858","is_oa":true,"landing_page_url":"https://doi.org/10.1099/mgen.0.000858","pdf_url":null,"source":{"id":"https://openalex.org/S4210186362","display_name":"Microbial Genomics","issn_l":"2057-5858","issn":["2057-5858"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320497","host_organization_name":"Microbiology Society","host_organization_lineage":["https://openalex.org/P4310320497"],"host_organization_lineage_names":["Microbiology Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbial Genomics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1099/mgen.0.000858","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067999103","display_name":"Cian Smyth","orcid":"https://orcid.org/0000-0003-4597-8611","observed_orcids":["https://orcid.org/0000-0003-4597-8611"]},"institutions":[{"id":"https://openalex.org/I157286207","display_name":"National University of Ireland, Maynooth","ror":"https://ror.org/048nfjm95","country_code":"IE","type":"education","lineage":["https://openalex.org/I157286207"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Cian Smyth","raw_affiliation_strings":["Antimicrobial Resistance & Microbiome Research Group, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Antimicrobial Resistance & Microbiome Research Group, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland","institution_ids":["https://openalex.org/I157286207"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077322919","display_name":"Robert J. Leigh","orcid":"https://orcid.org/0000-0002-7237-2394","observed_orcids":["https://orcid.org/0000-0002-7237-2394"]},"institutions":[{"id":"https://openalex.org/I157286207","display_name":"National University of Ireland, Maynooth","ror":"https://ror.org/048nfjm95","country_code":"IE","type":"education","lineage":["https://openalex.org/I157286207"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Robert J. Leigh","raw_affiliation_strings":["Antimicrobial Resistance & Microbiome Research Group, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Antimicrobial Resistance & Microbiome Research Group, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland","institution_ids":["https://openalex.org/I157286207"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103264269","display_name":"Sarah R. Delaney","orcid":"https://orcid.org/0000-0002-0301-4905","observed_orcids":["https://orcid.org/0000-0002-0301-4905"]},"institutions":[{"id":"https://openalex.org/I157286207","display_name":"National University of Ireland, Maynooth","ror":"https://ror.org/048nfjm95","country_code":"IE","type":"education","lineage":["https://openalex.org/I157286207"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Sarah Delaney","raw_affiliation_strings":["Antimicrobial Resistance & Microbiome Research Group, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Antimicrobial Resistance & Microbiome Research Group, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland","institution_ids":["https://openalex.org/I157286207"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003903867","display_name":"Richard A. Murphy","orcid":"https://orcid.org/0000-0002-4143-7431","observed_orcids":["https://orcid.org/0000-0002-4143-7431"]},"institutions":[{"id":"https://openalex.org/I4210128269","display_name":"Alltech (Ireland)","ror":"https://ror.org/03jnm8t41","country_code":"IE","type":"company","lineage":["https://openalex.org/I4210128269"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Richard A. Murphy","raw_affiliation_strings":["Alltech European Bioscience Centre, Dunboyne, Co. Meath, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alltech European Bioscience Centre, Dunboyne, Co. Meath, Ireland","institution_ids":["https://openalex.org/I4210128269"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022318756","display_name":"Fiona Walsh","orcid":"https://orcid.org/0000-0003-0789-1689","observed_orcids":["https://orcid.org/0000-0003-0789-1689"]},"institutions":[{"id":"https://openalex.org/I157286207","display_name":"National University of Ireland, Maynooth","ror":"https://ror.org/048nfjm95","country_code":"IE","type":"education","lineage":["https://openalex.org/I157286207"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Fiona Walsh","raw_affiliation_strings":["Antimicrobial Resistance & Microbiome Research Group, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland"],"raw_orcid":"https://orcid.org/0000-0003-0789-1689","affiliations":[{"raw_affiliation_string":"Antimicrobial Resistance & Microbiome Research Group, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland","institution_ids":["https://openalex.org/I157286207"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5022318756"],"corresponding_institution_ids":["https://openalex.org/I157286207"],"apc_list":{"value":1500,"currency":"GBP","value_usd":1839},"apc_paid":{"value":1500,"currency":"GBP","value_usd":1839},"fwci":0.5731,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.53396968,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"8","issue":"8","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10419","display_name":"Pharmaceutical and Antibiotic Environmental Impacts","score":0.0215000007301569,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.00839999970048666,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antimicrobial-resistance-plasmids","display_name":"antibiotic resistance plasmids","score":0.9929999709129333},{"id":"https://openalex.org/keywords/plasmid-mobility","display_name":"plasmid mobility","score":0.621999979019165},{"id":"https://openalex.org/keywords/one-health","display_name":"One Health","score":0.8309999704360962},{"id":"https://openalex.org/keywords/food-chain","display_name":"food chain","score":0.746999979019165},{"id":"https://openalex.org/keywords/antimicrobial-resistance-genes","display_name":"antimicrobial resistance genes","score":0.878000020980835},{"id":"https://openalex.org/keywords/metal-resistance-genes","display_name":"metal resistance genes","score":0.9890000224113464},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.9620000123977661},{"id":"https://openalex.org/keywords/phage-types","display_name":"phage types","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.9561744928359985},{"id":"https://openalex.org/C18103114","wikidata":"https://www.wikidata.org/wiki/Q1720369","display_name":"Replicon","level":4,"score":0.8886122107505798},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6685415506362915},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.647467851638794},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5852622985839844},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.5179042220115662},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.48730361461639404},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.34043896198272705},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.33845606446266174},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.2424508035182953}],"mesh":[{"descriptor_ui":"D000074823","descriptor_name":"One Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024881","descriptor_name":"Drug Resistance, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1099/mgen.0.000858","doi":"https://doi.org/10.1099/mgen.0.000858","is_oa":true,"landing_page_url":"https://doi.org/10.1099/mgen.0.000858","pdf_url":null,"source":{"id":"https://openalex.org/S4210186362","display_name":"Microbial Genomics","issn_l":"2057-5858","issn":["2057-5858"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320497","host_organization_name":"Microbiology Society","host_organization_lineage":["https://openalex.org/P4310320497"],"host_organization_lineage_names":["Microbiology Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbial Genomics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9484753","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9484753","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microb Genom","raw_type":"Text"},{"id":"pmid:35960657","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35960657","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbial genomics","raw_type":"Journal Article"},{"id":"pmh:oai:mural.maynoothuniversity.ie:18644","doi":null,"is_oa":false,"landing_page_url":"https://mural.maynoothuniversity.ie/id/eprint/18644/1/RL_shooting.pdf","pdf_url":"https://mural.maynoothuniversity.ie/id/eprint/18644/1/RL_shooting.pdf","source":{"id":"https://openalex.org/S4306401432","display_name":"Maynooth University ePrints and eTheses Archive (Maynooth University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I157286207","host_organization_name":"National University of Ireland, Maynooth","host_organization_lineage":["https://openalex.org/I157286207"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1099/mgen.0.000858","doi":"https://doi.org/10.1099/mgen.0.000858","is_oa":true,"landing_page_url":"https://doi.org/10.1099/mgen.0.000858","pdf_url":null,"source":{"id":"https://openalex.org/S4210186362","display_name":"Microbial Genomics","issn_l":"2057-5858","issn":["2057-5858"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320497","host_organization_name":"Microbiology Society","host_organization_lineage":["https://openalex.org/P4310320497"],"host_organization_lineage_names":["Microbiology Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbial Genomics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/2","score":0.40450000762939453,"display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8418990161","display_name":null,"funder_award_id":"ALMU_1","funder_id":"https://openalex.org/F4320310100","funder_display_name":"Alltech"}],"funders":[{"id":"https://openalex.org/F4320310100","display_name":"Alltech","ror":"https://ror.org/01gh6ja41"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1969307731","https://openalex.org/W2014816620","https://openalex.org/W2027184506","https://openalex.org/W2096093282","https://openalex.org/W2125474282","https://openalex.org/W2134375163","https://openalex.org/W2153325555","https://openalex.org/W2173913502","https://openalex.org/W2189116376","https://openalex.org/W2225557190","https://openalex.org/W2339423458","https://openalex.org/W2518643713","https://openalex.org/W2739323458","https://openalex.org/W2781831878","https://openalex.org/W2884929212","https://openalex.org/W2909601828","https://openalex.org/W2922563085","https://openalex.org/W2950150251","https://openalex.org/W2952167528","https://openalex.org/W2982531601","https://openalex.org/W3017386511","https://openalex.org/W3133381154","https://openalex.org/W3201580298","https://openalex.org/W3209528471","https://openalex.org/W3214956918","https://openalex.org/W3216382657","https://openalex.org/W4205455209","https://openalex.org/W4210359611","https://openalex.org/W4307407408","https://openalex.org/W6686723365"],"related_works":["https://openalex.org/W7167335290","https://openalex.org/W7169508851","https://openalex.org/W2891740273","https://openalex.org/W4383816978","https://openalex.org/W4399722271","https://openalex.org/W4224000275","https://openalex.org/W7134963254","https://openalex.org/W4410304563","https://openalex.org/W7063778114","https://openalex.org/W7222386722"],"abstract_inverted_index":{"Our":[0],"study":[1],"provides":[2],"novel":[3,73],"insights":[4],"into":[5],"the":[6,15,23,30,64],"global":[7],"nature":[8,25],"of":[9,22,26,40,70],"antimicrobial":[10],"resistance":[11,77],"(AMR)":[12],"plasmids":[13,28,36,50],"across":[14],"food":[16],"chain.":[17],"We":[18],"provide":[19],"compelling":[20],"evidence":[21],"globetrotting":[24],"AMR":[27,49,74],"and":[29,57,63,72,82],"need":[31],"for":[32,42],"surveillance":[33],"to":[34,44],"sequence":[35],"with":[37],"a":[38,68],"template":[39],"analyses":[41],"others":[43],"expand":[45],"these":[46],"data.":[47],"The":[48],"analysed":[51],"were":[52],"detected":[53],"in":[54,58],"63":[55],"countries":[56],"samples":[59],"from":[60],"humans,":[61],"animals":[62],"environment.":[65],"They":[66],"contained":[67],"combination":[69],"known":[71],"genes,":[75,78],"metal":[76],"virulence":[79],"factors,":[80],"phage":[81],"replicon":[83],"types.":[84]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-08-12T00:00:00"}