{"id":"https://openalex.org/W4290744543","doi":"https://doi.org/10.3389/frph.2022.963752","title":"The female reproductive tract microbiotas, inflammation, and gynecological conditions","display_name":"The female reproductive tract microbiotas, inflammation, and gynecological conditions","publication_year":2022,"publication_date":"2022-08-09","ids":{"openalex":"https://openalex.org/W4290744543","doi":"https://doi.org/10.3389/frph.2022.963752","pmid":"https://pubmed.ncbi.nlm.nih.gov/36303679","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9580710"},"language":"en","primary_location":{"id":"doi:10.3389/frph.2022.963752","doi":"https://doi.org/10.3389/frph.2022.963752","is_oa":true,"landing_page_url":"https://doi.org/10.3389/frph.2022.963752","pdf_url":"https://www.frontiersin.org/articles/10.3389/frph.2022.963752/pdf","source":{"id":"https://openalex.org/S4210207188","display_name":"Frontiers in Reproductive Health","issn_l":"2673-3153","issn":["2673-3153"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Reproductive Health","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/frph.2022.963752/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043963456","display_name":"Mahsa Gholiof","orcid":"https://orcid.org/0009-0003-6732-857X","observed_orcids":["https://orcid.org/0009-0003-6732-857X"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mahsa Gholiof","raw_affiliation_strings":["Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049132322","display_name":"Emma Adamson-De Luca","orcid":"https://orcid.org/0000-0002-1989-1806","observed_orcids":["https://orcid.org/0000-0002-1989-1806"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Emma Adamson-De Luca","raw_affiliation_strings":["AIMA Laboratories Inc., Hamilton, ON, Canada","Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIMA Laboratories Inc., Hamilton, ON, Canada","institution_ids":[]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086483789","display_name":"Jocelyn M. Wessels","orcid":"https://orcid.org/0000-0002-2065-690X","observed_orcids":["https://orcid.org/0000-0002-2065-690X"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Jocelyn M. Wessels","raw_affiliation_strings":["AIMA Laboratories Inc., Hamilton, ON, Canada","Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIMA Laboratories Inc., Hamilton, ON, Canada","institution_ids":[]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086483789"],"corresponding_institution_ids":["https://openalex.org/I98251732"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":3.2493,"has_fulltext":true,"cited_by_count":137,"citation_normalized_percentile":{"value":0.94719472,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"4","issue":null,"first_page":"963752","last_page":"963752"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/female-reproductive-tract-microbiota","display_name":"female reproductive tract microbiota","score":0.996999979019165},{"id":"https://openalex.org/keywords/dysbiosis","display_name":"dysbiosis","score":0.9020000100135803},{"id":"https://openalex.org/keywords/vaginal-microbiota","display_name":"vaginal microbiota","score":0.8240000009536743},{"id":"https://openalex.org/keywords/endometriosis","display_name":"endometriosis","score":0.7099999785423279},{"id":"https://openalex.org/keywords/infertility","display_name":"infertility","score":0.906000018119812},{"id":"https://openalex.org/keywords/endometrial-cancer","display_name":"endometrial cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":1.0},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6200000047683716},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9760000109672546},{"id":"https://openalex.org/keywords/local-immunity","display_name":"local immunity","score":0.8489999771118164},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.7429999709129333},{"id":"https://openalex.org/keywords/antibiotics","display_name":"antibiotics","score":0.8330000042915344},{"id":"https://openalex.org/keywords/gynecologic-conditions","display_name":"gynecologic conditions","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C2777165150","wikidata":"https://www.wikidata.org/wiki/Q269334","display_name":"Dysbiosis","level":3,"score":0.852530837059021},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7087333798408508},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6148832440376282},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5931867957115173},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5289376378059387},{"id":"https://openalex.org/C2777744392","wikidata":"https://www.wikidata.org/wiki/Q5880","display_name":"Vagina","level":2,"score":0.4930829703807831},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.48556992411613464},{"id":"https://openalex.org/C2779522080","wikidata":"https://www.wikidata.org/wiki/Q205764","display_name":"Endometriosis","level":2,"score":0.4790419340133667},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.4475840926170349},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.4292588233947754},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.41530871391296387},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3705178499221802},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.3235389292240143},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.275067538022995},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14310184121131897},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.13037541508674622},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.10929533839225769},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08963513374328613}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/frph.2022.963752","doi":"https://doi.org/10.3389/frph.2022.963752","is_oa":true,"landing_page_url":"https://doi.org/10.3389/frph.2022.963752","pdf_url":"https://www.frontiersin.org/articles/10.3389/frph.2022.963752/pdf","source":{"id":"https://openalex.org/S4210207188","display_name":"Frontiers in Reproductive Health","issn_l":"2673-3153","issn":["2673-3153"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Reproductive Health","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9580710","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9580710","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Reprod Health","raw_type":"Text"},{"id":"pmid:36303679","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36303679","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in reproductive health","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:16722171fa4046c9a4884d7e85caa5f1","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/16722171fa4046c9a4884d7e85caa5f1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Reproductive Health, Vol 4 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/frph.2022.963752","doi":"https://doi.org/10.3389/frph.2022.963752","is_oa":true,"landing_page_url":"https://doi.org/10.3389/frph.2022.963752","pdf_url":"https://www.frontiersin.org/articles/10.3389/frph.2022.963752/pdf","source":{"id":"https://openalex.org/S4210207188","display_name":"Frontiers in Reproductive Health","issn_l":"2673-3153","issn":["2673-3153"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Reproductive Health","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4290744543.pdf","grobid_xml":"https://content.openalex.org/works/W4290744543.grobid-xml"},"referenced_works_count":278,"referenced_works":["https://openalex.org/W170313005","https://openalex.org/W411732000","https://openalex.org/W627744320","https://openalex.org/W1474461326","https://openalex.org/W1497888109","https://openalex.org/W1511490662","https://openalex.org/W1517638146","https://openalex.org/W1534923950","https://openalex.org/W1547082834","https://openalex.org/W1548772785","https://openalex.org/W1593357338","https://openalex.org/W1611284225","https://openalex.org/W1655950349","https://openalex.org/W1761022945","https://openalex.org/W1820393462","https://openalex.org/W1839258374","https://openalex.org/W1868667984","https://openalex.org/W1902222982","https://openalex.org/W1906460723","https://openalex.org/W1919603305","https://openalex.org/W1930591173","https://openalex.org/W1939915698","https://openalex.org/W1964745652","https://openalex.org/W1968040003","https://openalex.org/W1970067305","https://openalex.org/W1975755498","https://openalex.org/W1976678129","https://openalex.org/W1976879190","https://openalex.org/W1977179183","https://openalex.org/W1978197327","https://openalex.org/W1979612247","https://openalex.org/W1981068366","https://openalex.org/W1981889797","https://openalex.org/W1985233850","https://openalex.org/W1986940747","https://openalex.org/W1991081822","https://openalex.org/W1991933056","https://openalex.org/W1995594306","https://openalex.org/W1997103485","https://openalex.org/W1997719514","https://openalex.org/W1998379649","https://openalex.org/W1998644615","https://openalex.org/W1999906527","https://openalex.org/W2003342633","https://openalex.org/W2006262878","https://openalex.org/W2007576427","https://openalex.org/W2008539591","https://openalex.org/W2010233561","https://openalex.org/W2010571114","https://openalex.org/W2010572285","https://openalex.org/W2011609277","https://openalex.org/W2013371150","https://openalex.org/W2013553461","https://openalex.org/W2019874049","https://openalex.org/W2025813544","https://openalex.org/W2027297424","https://openalex.org/W2028835702","https://openalex.org/W2031240692","https://openalex.org/W2032329981","https://openalex.org/W2036951019","https://openalex.org/W2037259928","https://openalex.org/W2037740265","https://openalex.org/W2042587841","https://openalex.org/W2044450804","https://openalex.org/W2046487574","https://openalex.org/W2046778696","https://openalex.org/W2046833861","https://openalex.org/W2048254575","https://openalex.org/W2049294941","https://openalex.org/W2049518790","https://openalex.org/W2049916860","https://openalex.org/W2051373931","https://openalex.org/W2052998574","https://openalex.org/W2054600286","https://openalex.org/W2055974926","https://openalex.org/W2057626594","https://openalex.org/W2058561523","https://openalex.org/W2058566083","https://openalex.org/W2059681003","https://openalex.org/W2064633474","https://openalex.org/W2066261417","https://openalex.org/W2066951766","https://openalex.org/W2069086657","https://openalex.org/W2073146544","https://openalex.org/W2083829960","https://openalex.org/W2084312540","https://openalex.org/W2088968901","https://openalex.org/W2093131922","https://openalex.org/W2094136374","https://openalex.org/W2095775470","https://openalex.org/W2100318919","https://openalex.org/W2101147372","https://openalex.org/W2101516199","https://openalex.org/W2102009960","https://openalex.org/W2103561589","https://openalex.org/W2106258306","https://openalex.org/W2107414352","https://openalex.org/W2107631420","https://openalex.org/W2108487398","https://openalex.org/W2110389012","https://openalex.org/W2110957620","https://openalex.org/W2112059343","https://openalex.org/W2112972569","https://openalex.org/W2113583367","https://openalex.org/W2114144364","https://openalex.org/W2116695192","https://openalex.org/W2117683486","https://openalex.org/W2119016404","https://openalex.org/W2121454015","https://openalex.org/W2122219094","https://openalex.org/W2126717573","https://openalex.org/W2132252324","https://openalex.org/W2132637540","https://openalex.org/W2132829999","https://openalex.org/W2142241097","https://openalex.org/W2144836936","https://openalex.org/W2145185252","https://openalex.org/W2145398766","https://openalex.org/W2147161211","https://openalex.org/W2147637673","https://openalex.org/W2154988722","https://openalex.org/W2156518020","https://openalex.org/W2158902491","https://openalex.org/W2159203244","https://openalex.org/W2160838901","https://openalex.org/W2163381424","https://openalex.org/W2164386968","https://openalex.org/W2165067288","https://openalex.org/W2165122496","https://openalex.org/W2166223274","https://openalex.org/W2167562610","https://openalex.org/W2168071294","https://openalex.org/W2170665356","https://openalex.org/W2204417727","https://openalex.org/W2252898612","https://openalex.org/W2293771134","https://openalex.org/W2302261222","https://openalex.org/W2323223570","https://openalex.org/W2325051054","https://openalex.org/W2327550909","https://openalex.org/W2336923645","https://openalex.org/W2342602136","https://openalex.org/W2405701971","https://openalex.org/W2411639498","https://openalex.org/W2435715880","https://openalex.org/W2479024870","https://openalex.org/W2491627885","https://openalex.org/W2518536270","https://openalex.org/W2528495505","https://openalex.org/W2529888004","https://openalex.org/W2549584821","https://openalex.org/W2553171810","https://openalex.org/W2555461010","https://openalex.org/W2557682897","https://openalex.org/W2559683962","https://openalex.org/W2569333997","https://openalex.org/W2569771289","https://openalex.org/W2588188994","https://openalex.org/W2593687742","https://openalex.org/W2594650517","https://openalex.org/W2598250701","https://openalex.org/W2601255746","https://openalex.org/W2605651569","https://openalex.org/W2622923993","https://openalex.org/W2734990933","https://openalex.org/W2753183473","https://openalex.org/W2761875562","https://openalex.org/W2765997255","https://openalex.org/W2766399118","https://openalex.org/W2766612280","https://openalex.org/W2777367044","https://openalex.org/W2786546763","https://openalex.org/W2789536221","https://openalex.org/W2795389370","https://openalex.org/W2795787346","https://openalex.org/W2796210912","https://openalex.org/W2800425585","https://openalex.org/W2802313285","https://openalex.org/W2802968642","https://openalex.org/W2806141241","https://openalex.org/W2807270740","https://openalex.org/W2884221096","https://openalex.org/W2887706592","https://openalex.org/W2889141154","https://openalex.org/W2891144094","https://openalex.org/W2896834919","https://openalex.org/W2898331057","https://openalex.org/W2899208785","https://openalex.org/W2901091086","https://openalex.org/W2901945219","https://openalex.org/W2903509631","https://openalex.org/W2904076340","https://openalex.org/W2909229435","https://openalex.org/W2910752853","https://openalex.org/W2911589499","https://openalex.org/W2912182143","https://openalex.org/W2920476467","https://openalex.org/W2920896335","https://openalex.org/W2922168348","https://openalex.org/W2925165927","https://openalex.org/W2938760353","https://openalex.org/W2942871689","https://openalex.org/W2943813693","https://openalex.org/W2944495648","https://openalex.org/W2945348578","https://openalex.org/W2947640277","https://openalex.org/W2950495320","https://openalex.org/W2952564192","https://openalex.org/W2956288366","https://openalex.org/W2958532943","https://openalex.org/W2960842261","https://openalex.org/W2965819385","https://openalex.org/W2968872535","https://openalex.org/W2968966670","https://openalex.org/W2970081482","https://openalex.org/W2973263350","https://openalex.org/W2975742314","https://openalex.org/W2977871370","https://openalex.org/W2983535424","https://openalex.org/W2998976548","https://openalex.org/W2999312903","https://openalex.org/W2999629551","https://openalex.org/W3000678207","https://openalex.org/W3005492068","https://openalex.org/W3007185356","https://openalex.org/W3007674389","https://openalex.org/W3010324698","https://openalex.org/W3011039914","https://openalex.org/W3012093490","https://openalex.org/W3012699620","https://openalex.org/W3014300728","https://openalex.org/W3015251032","https://openalex.org/W3015933390","https://openalex.org/W3030110112","https://openalex.org/W3034483708","https://openalex.org/W3035499280","https://openalex.org/W3043207992","https://openalex.org/W3045577170","https://openalex.org/W3045847394","https://openalex.org/W3045851146","https://openalex.org/W3048826881","https://openalex.org/W3084314451","https://openalex.org/W3085942695","https://openalex.org/W3094904088","https://openalex.org/W3097159994","https://openalex.org/W3099232652","https://openalex.org/W3103093168","https://openalex.org/W3108137971","https://openalex.org/W3111298271","https://openalex.org/W3115330566","https://openalex.org/W3120303381","https://openalex.org/W3126677987","https://openalex.org/W3128452648","https://openalex.org/W3134885188","https://openalex.org/W3135673673","https://openalex.org/W3137373834","https://openalex.org/W3140316273","https://openalex.org/W3150435962","https://openalex.org/W3160893537","https://openalex.org/W3165391538","https://openalex.org/W3172074343","https://openalex.org/W3178425719","https://openalex.org/W3182384550","https://openalex.org/W3185444663","https://openalex.org/W3197967892","https://openalex.org/W3200244616","https://openalex.org/W3201618473","https://openalex.org/W3210478802","https://openalex.org/W3212534846","https://openalex.org/W3216461242","https://openalex.org/W3216740638","https://openalex.org/W4200036959","https://openalex.org/W4220805857","https://openalex.org/W4221009865","https://openalex.org/W4231239830","https://openalex.org/W4234160457","https://openalex.org/W4290127738","https://openalex.org/W6713775946"],"related_works":["https://openalex.org/W7164930069","https://openalex.org/W4403988408","https://openalex.org/W4311705897","https://openalex.org/W4383820483","https://openalex.org/W7222997631","https://openalex.org/W4407291821","https://openalex.org/W4399941080","https://openalex.org/W7129651424","https://openalex.org/W7134054982","https://openalex.org/W3130906733"],"abstract_inverted_index":{"dominance.":[0],"This":[1,165],"concept":[2],"has":[3],"recently":[4],"been":[5],"challenged":[6],"as":[7,89,185],"women":[8],"can":[9,119,133,158,271],"have":[10,35,159],"a":[11,56,95,127],"diverse":[12],"vaginal":[13,112,117,135],"microbial":[14],"composition":[15],"in":[16,72,82,109,143,150,181,202,211,247,276],"the":[17,25,41,44,60,64,73,85,148,169,173,176,194,214,223,237,243],"absence":[18],"of":[19,24,46,94,106,175,216,236,261,280],"symptomatic":[20],"disease.":[21],"The":[22,91],"structures":[23],"upper":[26],"FRT":[27,61,86,99,156,177,224,244],"(the":[28],"endocervix,":[29],"uterus,":[30],"Fallopian":[31],"tubes,":[32],"and":[33,63,111,137,179,188,190,218,229,242,251,264,278],"ovaries)":[34],"distinct,":[36],"lower":[37],"biomass":[38],"microbiotas":[39,48,178],"than":[40],"vagina;":[42],"however,":[43,193],"existence":[45],"permanent":[47],"at":[49,207],"these":[50,203],"sites":[51],"is":[52,101,141,226,230,246,254],"disputed.":[53],"During":[54],"homeostasis,":[55],"balance":[57],"exists":[58],"between":[59,240],"bacteria":[62,199],"immune":[65,69,75],"system":[66],"that":[67,116],"maintains":[68],"quiescence.":[70],"Alterations":[71],"bacteria,":[74],"system,":[76],"or":[77,97],"local":[78,139],"environment":[79],"may":[80],"result":[81],"perturbances":[83],"to":[84,152,220,256,265,274],"microbiota,":[87],"defined":[88],"dysbiosis.":[90],"inflammatory":[92],"signature":[93],"perturbed":[96],"\"dysbiotic\"":[98],"microbiota":[100,149,225,245],"characterized":[102],"by":[103,122,197],"elevated":[104],"concentrations":[105],"pro-inflammatory":[107],"cytokines":[108],"cervical":[110],"fluid.":[113],"It":[114],"appears":[115],"homeostasis":[118],"be":[120,272],"disrupted":[121],"two":[123],"different":[124],"mechanisms:":[125],"first,":[126],"shift":[128],"toward":[129],"increased":[130],"bacterial":[131],"diversity":[132],"trigger":[134],"inflammation,":[136],"second,":[138],"immunity":[140,241],"altered":[142],"some":[144],"manner,":[145],"which":[146,198],"disrupts":[147],"response":[151],"an":[153],"environmental":[154],"change.":[155],"dysbiosis":[157],"negative":[160],"effects":[161],"on":[162],"reproductive":[163],"health.":[164],"review":[166],"will":[167],"examine":[168],"increasing":[170],"evidence":[171],"for":[172],"involvement":[174],"inflammation":[180],"gynecologic":[182,281],"conditions":[183,204],"such":[184],"endometriosis,":[186],"infertility,":[187],"endometrial":[189],"ovarian":[191],"cancer;":[192],"precise":[195],"mechanisms":[196],"are":[200],"involved":[201],"remains":[205],"speculative":[206],"present.":[208],"While":[209],"only":[210],"their":[212],"infancy,":[213],"use":[215],"antibiotics":[217],"probiotics":[219],"therapeutically":[221],"alter":[222],"being":[227],"studied":[228],"discussed":[231],"herein.":[232],"Our":[233],"current":[234],"understanding":[235,260],"intimate":[238],"relationship":[239,263],"its":[248],"early":[249],"days,":[250],"more":[252],"research":[253],"needed":[255],"deepen":[257],"our":[258,268],"mechanistic":[259],"this":[262],"assess":[266],"how":[267],"present":[269],"knowledge":[270],"harnessed":[273],"assist":[275],"diagnosis":[277],"treatment":[279],"conditions.":[282]},"counts_by_year":[{"year":2026,"cited_by_count":36},{"year":2025,"cited_by_count":49},{"year":2024,"cited_by_count":38},{"year":2023,"cited_by_count":14}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-08-09T00:00:00"}