{"id":"https://openalex.org/W4290724595","doi":"https://doi.org/10.1038/s41416-022-01922-3","title":"Patient attrition in Molecular Tumour Boards: a systematic review","display_name":"Patient attrition in Molecular Tumour Boards: a systematic review","publication_year":2022,"publication_date":"2022-08-08","ids":{"openalex":"https://openalex.org/W4290724595","doi":"https://doi.org/10.1038/s41416-022-01922-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/35941175","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9553981"},"language":"en","primary_location":{"id":"doi:10.1038/s41416-022-01922-3","doi":"https://doi.org/10.1038/s41416-022-01922-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41416-022-01922-3","pdf_url":"https://www.nature.com/articles/s41416-022-01922-3.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.nature.com/articles/s41416-022-01922-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019524414","display_name":"Hannah Frost","orcid":"https://orcid.org/0000-0002-4398-0382","observed_orcids":["https://orcid.org/0000-0002-4398-0382"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210129527","display_name":"Cancer Research UK Manchester Institute","ror":"https://ror.org/037405c78","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801316944","https://openalex.org/I28407311","https://openalex.org/I4210129527"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Hannah Frost","raw_affiliation_strings":["Department of Computer Science, University of Manchester, Manchester, UK. Hannah.frost@digitalecmt.org","Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK. Hannah.frost@digitalecmt.org","Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK"],"raw_orcid":"https://orcid.org/0000-0002-4398-0382","affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Manchester, Manchester, UK. Hannah.frost@digitalecmt.org","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK. Hannah.frost@digitalecmt.org","institution_ids":["https://openalex.org/I4210129527"]},{"raw_affiliation_string":"Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK","institution_ids":["https://openalex.org/I4210129527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022848214","display_name":"Donna M. Graham","orcid":"https://orcid.org/0000-0001-6500-8140","observed_orcids":["https://orcid.org/0000-0001-6500-8140"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210129527","display_name":"Cancer Research UK Manchester Institute","ror":"https://ror.org/037405c78","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801316944","https://openalex.org/I28407311","https://openalex.org/I4210129527"]},{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Donna M. Graham","raw_affiliation_strings":["Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK","Division of Cancer Sciences, The University of Manchester, Manchester, UK","Experimental Cancer Medicine Team, The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK","institution_ids":["https://openalex.org/I4210129527"]},{"raw_affiliation_string":"Division of Cancer Sciences, The University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Experimental Cancer Medicine Team, The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033090749","display_name":"Louise Carter","orcid":"https://orcid.org/0000-0002-9854-2304","observed_orcids":["https://orcid.org/0000-0002-9854-2304"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210133995","display_name":"The Christie NHS Foundation Trust","ror":"https://ror.org/03v9efr22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210133995"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Louise Carter","raw_affiliation_strings":["Division of Cancer Sciences, The University of Manchester, Manchester, UK","Experimental Cancer Medicine Team, The Christie NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Sciences, The University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Experimental Cancer Medicine Team, The Christie NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210133995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015115681","display_name":"Paul O\u2019Regan","orcid":"https://orcid.org/0000-0002-0231-5028","observed_orcids":["https://orcid.org/0000-0002-0231-5028"]},"institutions":[{"id":"https://openalex.org/I4210129527","display_name":"Cancer Research UK Manchester Institute","ror":"https://ror.org/037405c78","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801316944","https://openalex.org/I28407311","https://openalex.org/I4210129527"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul O\u2019Regan","raw_affiliation_strings":["Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK","institution_ids":["https://openalex.org/I4210129527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071160473","display_name":"D\u00f3nal Landers","orcid":"https://orcid.org/0000-0001-8376-9779","observed_orcids":["https://orcid.org/0000-0001-8376-9779"]},"institutions":[{"id":"https://openalex.org/I4210129527","display_name":"Cancer Research UK Manchester Institute","ror":"https://ror.org/037405c78","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801316944","https://openalex.org/I28407311","https://openalex.org/I4210129527"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D\u00f3nal Landers","raw_affiliation_strings":["Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK","institution_ids":["https://openalex.org/I4210129527"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053978668","display_name":"Andr\u00e9 Freitas","orcid":"https://orcid.org/0000-0002-4430-4837","observed_orcids":["https://orcid.org/0000-0002-4430-4837","https://orcid.org/0000-0001-9907-3645"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210129527","display_name":"Cancer Research UK Manchester Institute","ror":"https://ror.org/037405c78","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801316944","https://openalex.org/I28407311","https://openalex.org/I4210129527"]},{"id":"https://openalex.org/I7495430","display_name":"Idiap Research Institute","ror":"https://ror.org/05932h694","country_code":"CH","type":"facility","lineage":["https://openalex.org/I7495430"]}],"countries":["CH","GB"],"is_corresponding":false,"raw_author_name":"Andr\u00e9 Freitas","raw_affiliation_strings":["Department of Computer Science, University of Manchester, Manchester, UK","Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK","Idiap Research Institute, Martigny, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Digital Experimental Cancer Medicine Team, Cancer Research UK Manchester Institute Cancer Biomarker Centre, Manchester, UK","institution_ids":["https://openalex.org/I4210129527"]},{"raw_affiliation_string":"Idiap Research Institute, Martigny, Switzerland","institution_ids":["https://openalex.org/I7495430"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5019524414"],"corresponding_institution_ids":["https://openalex.org/I28407311","https://openalex.org/I4210129527"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":{"value":4480,"currency":"USD","value_usd":4480},"fwci":0.2926,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.29535398,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"127","issue":"8","first_page":"1557","last_page":"1564"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.5098000168800354,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.5098000168800354,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.2240999937057495,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.1754000037908554,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-tumor-board","display_name":"molecular tumor board","score":0.9739999771118164},{"id":"https://openalex.org/keywords/patient-dropout","display_name":"patient dropout","score":0.9929999709129333},{"id":"https://openalex.org/keywords/precision-oncology","display_name":"precision oncology","score":0.8069999814033508},{"id":"https://openalex.org/keywords/actionable-mutations","display_name":"actionable mutations","score":0.7799999713897705},{"id":"https://openalex.org/keywords/barriers-to-treatment","display_name":"barriers to treatment","score":0.7940000295639038},{"id":"https://openalex.org/keywords/clinical-deterioration","display_name":"clinical deterioration","score":0.5709999799728394},{"id":"https://openalex.org/keywords/clinical-decision-making","display_name":"clinical decision-making","score":0.6499999761581421},{"id":"https://openalex.org/keywords/multi-omics-integration","display_name":"multi-omics integration","score":0.6190000176429749}],"concepts":[{"id":"https://openalex.org/C2780553607","wikidata":"https://www.wikidata.org/wiki/Q684868","display_name":"Attrition","level":2,"score":0.7572953701019287},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6707988977432251},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.5166395306587219},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.48441675305366516},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.42238226532936096},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.39038121700286865},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.30041736364364624},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.19273844361305237},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.07016730308532715},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000066491","descriptor_name":"Clinical Decision-Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000075902","descriptor_name":"Clinical Deterioration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1038/s41416-022-01922-3","doi":"https://doi.org/10.1038/s41416-022-01922-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41416-022-01922-3","pdf_url":"https://www.nature.com/articles/s41416-022-01922-3.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},{"id":"doi:10.1101/2021.10.07.21264241","doi":"https://doi.org/10.1101/2021.10.07.21264241","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.10.07.21264241","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2021/12/09/2021.10.07.21264241.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:35941175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35941175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9553981","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9553981/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Cancer","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire/ea683f8d-6cc9-4b2a-95d6-467af4a80746","doi":null,"is_oa":true,"landing_page_url":"https://www.mendeley.com/catalogue/067158b0-760d-3496-bb5b-ede406c4a299/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frost, H, Graham, D M, Carter, L, O\u2019Regan, P, Landers, D & Freitas, A 2022, 'Patient attrition in Molecular Tumour Boards: a systematic review', British Journal of Cancer, vol. 127, no. 8, pp. 1557-1564. https://doi.org/10.1038/s41416-022-01922-3","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/7cd73573-43f5-4fb8-b26e-3bf3acd94ce3","doi":null,"is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/7cd73573-43f5-4fb8-b26e-3bf3acd94ce3","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frost, H, Graham, D M, Carter, L, O\u2019Regan, P, Landers, D & Freitas, A 2021, 'Patient attrition in Molecular Tumour Boards : A Review', medRxiv. https://doi.org/10.1101/2021.10.07.21264241","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/s41416-022-01922-3","doi":"https://doi.org/10.1038/s41416-022-01922-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41416-022-01922-3","pdf_url":"https://www.nature.com/articles/s41416-022-01922-3.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[{"id":"https://openalex.org/G1243932596","display_name":null,"funder_award_id":"A29374","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G1876893744","display_name":null,"funder_award_id":"119106","funder_id":"https://openalex.org/F4320307770","funder_display_name":"AstraZeneca"},{"id":"https://openalex.org/G373937675","display_name":null,"funder_award_id":"29374","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G4291948961","display_name":null,"funder_award_id":"A25254","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G4869084219","display_name":null,"funder_award_id":"C147/A25254","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"}],"funders":[{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320323054","display_name":"Associazione Italiana per la Ricerca sul Cancro","ror":"https://ror.org/02g2x7380"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4290724595.pdf","grobid_xml":"https://content.openalex.org/works/W4290724595.grobid-xml"},"referenced_works_count":98,"referenced_works":["https://openalex.org/W1740929737","https://openalex.org/W1974159927","https://openalex.org/W2014275502","https://openalex.org/W2035563427","https://openalex.org/W2043990618","https://openalex.org/W2051380427","https://openalex.org/W2102922616","https://openalex.org/W2104287359","https://openalex.org/W2106410630","https://openalex.org/W2108696783","https://openalex.org/W2109218597","https://openalex.org/W2119133440","https://openalex.org/W2127250774","https://openalex.org/W2138809303","https://openalex.org/W2171237493","https://openalex.org/W2294395959","https://openalex.org/W2298079736","https://openalex.org/W2306999703","https://openalex.org/W2310698129","https://openalex.org/W2322775477","https://openalex.org/W2408112818","https://openalex.org/W2486004214","https://openalex.org/W2503515884","https://openalex.org/W2514723195","https://openalex.org/W2515944999","https://openalex.org/W2549976854","https://openalex.org/W2557397534","https://openalex.org/W2561791594","https://openalex.org/W2564365886","https://openalex.org/W2582016570","https://openalex.org/W2586358969","https://openalex.org/W2587368716","https://openalex.org/W2589237569","https://openalex.org/W2591662301","https://openalex.org/W2601520864","https://openalex.org/W2605856145","https://openalex.org/W2611036358","https://openalex.org/W2620581814","https://openalex.org/W2622985700","https://openalex.org/W2622995533","https://openalex.org/W2681535791","https://openalex.org/W2743800325","https://openalex.org/W2761073025","https://openalex.org/W2763133656","https://openalex.org/W2763785377","https://openalex.org/W2765921250","https://openalex.org/W2770203518","https://openalex.org/W2775546364","https://openalex.org/W2778576237","https://openalex.org/W2792413408","https://openalex.org/W2792425071","https://openalex.org/W2795373371","https://openalex.org/W2795628031","https://openalex.org/W2800576115","https://openalex.org/W2801264239","https://openalex.org/W2801634390","https://openalex.org/W2808798054","https://openalex.org/W2884077015","https://openalex.org/W2888297491","https://openalex.org/W2890394888","https://openalex.org/W2897726960","https://openalex.org/W2899401372","https://openalex.org/W2902132411","https://openalex.org/W2902296338","https://openalex.org/W2922463680","https://openalex.org/W2924972479","https://openalex.org/W2938206352","https://openalex.org/W2938634307","https://openalex.org/W2938864889","https://openalex.org/W2939762749","https://openalex.org/W2941224329","https://openalex.org/W2943951816","https://openalex.org/W2950306568","https://openalex.org/W2956010369","https://openalex.org/W2962862689","https://openalex.org/W2963260826","https://openalex.org/W2963575612","https://openalex.org/W2972626680","https://openalex.org/W2973864382","https://openalex.org/W2974820548","https://openalex.org/W2977181930","https://openalex.org/W2987220110","https://openalex.org/W2998575133","https://openalex.org/W2999102768","https://openalex.org/W3000668520","https://openalex.org/W3001646965","https://openalex.org/W3009926768","https://openalex.org/W3013242029","https://openalex.org/W3021833419","https://openalex.org/W3032567649","https://openalex.org/W3035877426","https://openalex.org/W3087732728","https://openalex.org/W3089562193","https://openalex.org/W3091487387","https://openalex.org/W3111725249","https://openalex.org/W3128369052","https://openalex.org/W3140760072","https://openalex.org/W3182939006"],"related_works":["https://openalex.org/W7170180537","https://openalex.org/W4362612934","https://openalex.org/W3135065167","https://openalex.org/W4411200114","https://openalex.org/W2956010369","https://openalex.org/W7164057381","https://openalex.org/W4284969826","https://openalex.org/W4397006959","https://openalex.org/W4408220161","https://openalex.org/W4402451869"],"abstract_inverted_index":{"BACKGROUND:":[0],"Molecular":[1],"Tumour":[2],"Boards":[3],"(MTBs)":[4],"were":[5,77,109,124],"created":[6],"with":[7,133,150],"the":[8,28,96,106,145],"purpose":[9],"of":[10,31,74,91,131,147,189],"supporting":[11],"clinical":[12,119,158],"decision-making":[13],"within":[14,64],"precision":[15],"medicine.":[16],"Though":[17],"in":[18,164,175],"use":[19],"globally,":[20],"reporting":[21,130,136,143,156,179],"on":[22,27,137,144,157],"these":[23],"meetings":[24],"often":[25,125],"focuses":[26],"small":[29],"percentages":[30],"patients":[32,48,69,92,138],"that":[33,101],"receive":[34,52,104],"treatment":[35,94,152,186,199],"via":[36],"this":[37],"process":[38,195],"and":[39,46,66,118,154,187,198],"are":[40],"less":[41],"likely":[42],"to":[43,60,68,128,174,182,185,194],"report":[44],"on,":[45],"assess,":[47],"who":[49],"do":[50],"not":[51,103],"treatment.":[53,71],"METHODS:":[54],"A":[55,72],"literature":[56],"review":[57],"was":[58],"performed":[59],"understand":[61,183],"patient":[62,162],"attrition":[63,163],"MTBs":[65,132,165],"barriers":[67,184],"receiving":[70],"total":[73],"51":[75],"papers":[76],"reviewed":[78],"spanning":[79],"a":[80],"6-year":[81],"period":[82],"from":[83],"11":[84],"different":[85],"countries.":[86],"RESULTS:":[87],"In":[88],"total,":[89],"20%":[90],"received":[93],"through":[95],"MTB":[97],"process.":[98],"Of":[99],"those":[100],"did":[102],"treatment,":[105],"main":[107],"reasons":[108],"no":[110,114,140,151],"mutations":[111,116,149],"identified":[112],"(27%),":[113],"actionable":[115,148],"(22%)":[117],"deterioration":[120],"(15%).":[121],"However,":[122],"data":[123],"incomplete":[126],"due":[127],"inconsistent":[129],"only":[134],"55%":[135,142],"having":[139],"mutations,":[141],"presence":[146],"options":[153],"59%":[155],"deterioration.":[159],"DISCUSSION:":[160],"As":[161],"is":[166,170,180,192],"an":[167],"issue":[168],"which":[169],"very":[171],"rarely":[172],"alluded":[173],"reporting,":[176],"more":[177],"transparent":[178],"needed":[181],"integration":[188],"new":[190],"technologies":[191],"required":[193],"increasing":[196],"omic":[197],"data.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-08-09T00:00:00"}
