{"id":"https://openalex.org/W4290706288","doi":"https://doi.org/10.1016/j.jpba.2022.114987","title":"Recent challenges and trends in forensic analysis: \u03949-THC isomers pharmacology, toxicology and analysis","display_name":"Recent challenges and trends in forensic analysis: \u03949-THC isomers pharmacology, toxicology and analysis","publication_year":2022,"publication_date":"2022-08-08","ids":{"openalex":"https://openalex.org/W4290706288","doi":"https://doi.org/10.1016/j.jpba.2022.114987","pmid":"https://pubmed.ncbi.nlm.nih.gov/35985136"},"language":"en","primary_location":{"id":"doi:10.1016/j.jpba.2022.114987","doi":"https://doi.org/10.1016/j.jpba.2022.114987","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jpba.2022.114987","pdf_url":null,"source":{"id":"https://openalex.org/S174893293","display_name":"Journal of Pharmaceutical and Biomedical Analysis","issn_l":"0731-7085","issn":["0731-7085","1873-264X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical and Biomedical Analysis","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007031667","display_name":"Nunzia La Maida","orcid":"https://orcid.org/0000-0003-0127-4225","observed_orcids":["https://orcid.org/0000-0003-0127-4225"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Nunzia La Maida","raw_affiliation_strings":["Unit of Forensic Toxicology, Department of Anatomical, Histological, Forensic, and Orthopedic Sciences, Universit\u00e0 la Sapienza, V. Le Regina Elena 366, 00161 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Forensic Toxicology, Department of Anatomical, Histological, Forensic, and Orthopedic Sciences, Universit\u00e0 la Sapienza, V. Le Regina Elena 366, 00161 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003140018","display_name":"Alessandro Di Giorgi","orcid":"https://orcid.org/0000-0003-2997-221X","observed_orcids":["https://orcid.org/0000-0003-2997-221X"]},"institutions":[{"id":"https://openalex.org/I122534668","display_name":"Marche Polytechnic University","ror":"https://ror.org/00x69rs40","country_code":"IT","type":"education","lineage":["https://openalex.org/I122534668"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Di Giorgi","raw_affiliation_strings":["Department of Excellence of Biomedical Science and Public Health, University \"Politecnica delle Marche\" of Ancona, Via Tronto 10/a, 60124, Ancona, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Excellence of Biomedical Science and Public Health, University \"Politecnica delle Marche\" of Ancona, Via Tronto 10/a, 60124, Ancona, Italy","institution_ids":["https://openalex.org/I122534668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053212432","display_name":"Simona Pichini","orcid":"https://orcid.org/0000-0002-6347-0750","observed_orcids":["https://orcid.org/0000-0002-6347-0750"]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Simona Pichini","raw_affiliation_strings":["National Centre on Addiction and Doping, Istituto Superiore di Sanit\u00e0, V. Le Regina Elena 299, 00161 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Centre on Addiction and Doping, Istituto Superiore di Sanit\u00e0, V. Le Regina Elena 299, 00161 Rome, Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002872494","display_name":"Francesco Paolo Busard\u00f2","orcid":"https://orcid.org/0000-0002-3082-4532","observed_orcids":["https://orcid.org/0000-0002-3082-4532"]},"institutions":[{"id":"https://openalex.org/I122534668","display_name":"Marche Polytechnic University","ror":"https://ror.org/00x69rs40","country_code":"IT","type":"education","lineage":["https://openalex.org/I122534668"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Francesco Paolo Busard\u00f2","raw_affiliation_strings":["Department of Excellence of Biomedical Science and Public Health, University \"Politecnica delle Marche\" of Ancona, Via Tronto 10/a, 60124, Ancona, Italy. Electronic address: fra.busardo@libero.it"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Excellence of Biomedical Science and Public Health, University \"Politecnica delle Marche\" of Ancona, Via Tronto 10/a, 60124, Ancona, Italy. Electronic address: fra.busardo@libero.it","institution_ids":["https://openalex.org/I122534668"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000016116","display_name":"Marilyn Ann Huestis","orcid":"https://orcid.org/0000-0003-2137-4645","observed_orcids":["https://orcid.org/0000-0003-2137-4645"]},"institutions":[{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marilyn A. Huestis","raw_affiliation_strings":["Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I149251103"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5002872494"],"corresponding_institution_ids":["https://openalex.org/I122534668"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":0.8675,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.63592233,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"220","issue":null,"first_page":"114987","last_page":"114987"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.024399999529123306,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/delta9-tetrahydrocannabinol","display_name":"delta-9-tetrahydrocannabinol","score":0.9190000295639038},{"id":"https://openalex.org/keywords/delta-8-tetrahydrocannabinol","display_name":"delta-8-tetrahydrocannabinol","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hemp","display_name":"hemp","score":0.5580000281333923},{"id":"https://openalex.org/keywords/e-cigarette-liquid","display_name":"e-cigarette liquid","score":0.6890000104904175},{"id":"https://openalex.org/keywords/cannabis-products","display_name":"cannabis products","score":0.6190000176429749},{"id":"https://openalex.org/keywords/toxicology","display_name":"toxicology","score":0.4259999990463257},{"id":"https://openalex.org/keywords/pharmacology","display_name":"pharmacology","score":0.843999981880188},{"id":"https://openalex.org/keywords/potency","display_name":"potency","score":0.4350000023841858},{"id":"https://openalex.org/keywords/forensic-analysis","display_name":"forensic analysis","score":0.5440000295639038},{"id":"https://openalex.org/keywords/analytical-methods","display_name":"analytical methods","score":0.6000000238418579},{"id":"https://openalex.org/keywords/lc-ms","display_name":"LC-MS","score":0.5429999828338623},{"id":"https://openalex.org/keywords/gas-chromatography-mass-spectrometry","display_name":"gas chromatography-mass spectrometry","score":0.8080000281333923}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8599886894226074},{"id":"https://openalex.org/C158342456","wikidata":"https://www.wikidata.org/wiki/Q587862","display_name":"Forensic toxicology","level":2,"score":0.6416414380073547},{"id":"https://openalex.org/C38829236","wikidata":"https://www.wikidata.org/wiki/Q203994","display_name":"Euphoriant","level":2,"score":0.6382433772087097},{"id":"https://openalex.org/C2777056318","wikidata":"https://www.wikidata.org/wiki/Q79817","display_name":"Cannabis","level":2,"score":0.6106473207473755},{"id":"https://openalex.org/C2778563155","wikidata":"https://www.wikidata.org/wiki/Q190067","display_name":"Tetrahydrocannabinol","level":4,"score":0.5170905590057373},{"id":"https://openalex.org/C2778961205","wikidata":"https://www.wikidata.org/wiki/Q1200715","display_name":"Designer drug","level":3,"score":0.49932289123535156},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4927380383014679},{"id":"https://openalex.org/C2781090866","wikidata":"https://www.wikidata.org/wiki/Q265831","display_name":"Cannabinol","level":4,"score":0.4904296100139618},{"id":"https://openalex.org/C2908858883","wikidata":"https://www.wikidata.org/wiki/Q2705066","display_name":"Dronabinol","level":4,"score":0.4883517920970917},{"id":"https://openalex.org/C2777846614","wikidata":"https://www.wikidata.org/wiki/Q19904200","display_name":"Synthetic cannabinoids","level":4,"score":0.48596107959747314},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.4646555781364441},{"id":"https://openalex.org/C2780871563","wikidata":"https://www.wikidata.org/wiki/Q422936","display_name":"Cannabinoid","level":3,"score":0.43510931730270386},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3889561593532562},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.36743098497390747},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.1688215136528015},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0969487726688385},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08638402819633484},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000700","descriptor_name":"Analgesics","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002188","descriptor_name":"Cannabis","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006213","descriptor_name":"Hallucinogens","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D008401","descriptor_name":"Gas Chromatography-Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013759","descriptor_name":"Dronabinol","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D013759","descriptor_name":"Dronabinol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066300","descriptor_name":"Electronic Nicotine Delivery Systems","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jpba.2022.114987","doi":"https://doi.org/10.1016/j.jpba.2022.114987","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jpba.2022.114987","pdf_url":null,"source":{"id":"https://openalex.org/S174893293","display_name":"Journal of Pharmaceutical and Biomedical Analysis","issn_l":"0731-7085","issn":["0731-7085","1873-264X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical and Biomedical Analysis","raw_type":"journal-article"},{"id":"pmid:35985136","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35985136","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pharmaceutical and biomedical analysis","raw_type":"Journal Article"},{"id":"pmh:oai:iris.univpm.it:11566/322015","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11566/322015","pdf_url":null,"source":{"id":"https://openalex.org/S4306402571","display_name":"Universit\u00e0 Politecnica delle Marche (Universit\u00e0 Politecnica delle Marche)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122534668","host_organization_name":"Marche Polytechnic University","host_organization_lineage":["https://openalex.org/I122534668"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":94,"referenced_works":["https://openalex.org/W165663473","https://openalex.org/W192454658","https://openalex.org/W1971939417","https://openalex.org/W1973423612","https://openalex.org/W1974279849","https://openalex.org/W1983397045","https://openalex.org/W1990534478","https://openalex.org/W1993185434","https://openalex.org/W1994460020","https://openalex.org/W1995552285","https://openalex.org/W1996546122","https://openalex.org/W2000901107","https://openalex.org/W2003461183","https://openalex.org/W2004053486","https://openalex.org/W2004508431","https://openalex.org/W2012385894","https://openalex.org/W2013713755","https://openalex.org/W2014873841","https://openalex.org/W2017245119","https://openalex.org/W2017374188","https://openalex.org/W2018810438","https://openalex.org/W2023366312","https://openalex.org/W2030021261","https://openalex.org/W2034440394","https://openalex.org/W2038222838","https://openalex.org/W2039874846","https://openalex.org/W2048991222","https://openalex.org/W2051194261","https://openalex.org/W2052486523","https://openalex.org/W2052590486","https://openalex.org/W2066985048","https://openalex.org/W2071014521","https://openalex.org/W2072945404","https://openalex.org/W2075056398","https://openalex.org/W2075850387","https://openalex.org/W2075881972","https://openalex.org/W2077394774","https://openalex.org/W2078044784","https://openalex.org/W2079166576","https://openalex.org/W2093313206","https://openalex.org/W2116019975","https://openalex.org/W2118744052","https://openalex.org/W2126657900","https://openalex.org/W2165789750","https://openalex.org/W2170857974","https://openalex.org/W2201370322","https://openalex.org/W2235818701","https://openalex.org/W2258585991","https://openalex.org/W2324311973","https://openalex.org/W2414085421","https://openalex.org/W2430574888","https://openalex.org/W2469061880","https://openalex.org/W2530668387","https://openalex.org/W2583134819","https://openalex.org/W2587433492","https://openalex.org/W2595660268","https://openalex.org/W2743122121","https://openalex.org/W2767091853","https://openalex.org/W2780551931","https://openalex.org/W2786945379","https://openalex.org/W2810906630","https://openalex.org/W2884846919","https://openalex.org/W2912537816","https://openalex.org/W2919331707","https://openalex.org/W2965854611","https://openalex.org/W2975277924","https://openalex.org/W2978902730","https://openalex.org/W3007507737","https://openalex.org/W3033126749","https://openalex.org/W3094735181","https://openalex.org/W3109429553","https://openalex.org/W3139498866","https://openalex.org/W3164160477","https://openalex.org/W3167190606","https://openalex.org/W3183583060","https://openalex.org/W3197285055","https://openalex.org/W3198625691","https://openalex.org/W3199188264","https://openalex.org/W3207791946","https://openalex.org/W3210739779","https://openalex.org/W3214406729","https://openalex.org/W3214828851","https://openalex.org/W4200319280","https://openalex.org/W4200571375","https://openalex.org/W4212813950","https://openalex.org/W4220907918","https://openalex.org/W4224305342","https://openalex.org/W4229004415","https://openalex.org/W4242912487","https://openalex.org/W4284885388","https://openalex.org/W6648739136","https://openalex.org/W6654391003","https://openalex.org/W6654933872","https://openalex.org/W6678320521"],"related_works":["https://openalex.org/W1984940392","https://openalex.org/W4212813950","https://openalex.org/W4407344668","https://openalex.org/W4408588516","https://openalex.org/W4389763523","https://openalex.org/W4416777195","https://openalex.org/W4385563788","https://openalex.org/W4408284194","https://openalex.org/W7163172264","https://openalex.org/W4408085458"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-08-09T00:00:00"}