{"id":"https://openalex.org/W4290565880","doi":"https://doi.org/10.3389/fphys.2022.923555","title":"Analysis of 16 studies in nine rodent models does not support the hypothesis that diabetic polyuria is a main reason of urinary bladder enlargement","display_name":"Analysis of 16 studies in nine rodent models does not support the hypothesis that diabetic polyuria is a main reason of urinary bladder enlargement","publication_year":2022,"publication_date":"2022-08-08","ids":{"openalex":"https://openalex.org/W4290565880","doi":"https://doi.org/10.3389/fphys.2022.923555","pmid":"https://pubmed.ncbi.nlm.nih.gov/36003651","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9393211"},"language":"en","primary_location":{"id":"doi:10.3389/fphys.2022.923555","doi":"https://doi.org/10.3389/fphys.2022.923555","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2022.923555","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2022.923555/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fphys.2022.923555/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070100683","display_name":"Zeynep Elif Ye\u015filyurt","orcid":"https://orcid.org/0000-0001-5659-8839","observed_orcids":["https://orcid.org/0000-0001-5659-8839"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Zeynep E. Yesilyurt","raw_affiliation_strings":["Dept. of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey","Department of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]},{"raw_affiliation_string":"Department of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007578013","display_name":"Jan Matthes","orcid":"https://orcid.org/0000-0003-2754-1555","observed_orcids":["https://orcid.org/0000-0003-2754-1555"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jan Matthes","raw_affiliation_strings":["Dept. of Pharmacology, University of Cologne, Cologne, Germany","Department of Pharmacology, University of Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pharmacology, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]},{"raw_affiliation_string":"Department of Pharmacology, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085217351","display_name":"Edith Hintermann","orcid":"https://orcid.org/0000-0002-0943-8098","observed_orcids":["https://orcid.org/0000-0002-0943-8098"]},"institutions":[{"id":"https://openalex.org/I114090438","display_name":"Goethe University Frankfurt","ror":"https://ror.org/04cvxnb49","country_code":"DE","type":"education","lineage":["https://openalex.org/I114090438"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Edith Hintermann","raw_affiliation_strings":["Pharmazentrum, Goethe University, Frankfurt, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0943-8098","affiliations":[{"raw_affiliation_string":"Pharmazentrum, Goethe University, Frankfurt, Germany","institution_ids":["https://openalex.org/I114090438"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005772090","display_name":"Tamara R. Casta\u00f1eda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210138838","display_name":"Sanofi (Germany)","ror":"https://ror.org/03ytdtb31","country_code":"DE","type":"company","lineage":["https://openalex.org/I3018075036","https://openalex.org/I4210138838"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tamara R. Casta\u00f1eda","raw_affiliation_strings":["Sanofi Research and Development, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Research and Development, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210138838"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025554378","display_name":"Ralf Elvert","orcid":"https://orcid.org/0000-0003-1216-307X","observed_orcids":["https://orcid.org/0000-0003-1216-307X"]},"institutions":[{"id":"https://openalex.org/I4210138838","display_name":"Sanofi (Germany)","ror":"https://ror.org/03ytdtb31","country_code":"DE","type":"company","lineage":["https://openalex.org/I3018075036","https://openalex.org/I4210138838"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ralf Elvert","raw_affiliation_strings":["Sanofi Research and Development, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Research and Development, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210138838"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009052329","display_name":"Jesus Hernan Beltran\u2010Ornelas","orcid":"https://orcid.org/0000-0003-2075-8313","observed_orcids":["https://orcid.org/0000-0003-2075-8313"]},"institutions":[{"id":"https://openalex.org/I68368234","display_name":"Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/009eqmr18","country_code":"MX","type":"facility","lineage":["https://openalex.org/I59361560","https://openalex.org/I68368234"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Jesus H. Beltran-Ornelas","raw_affiliation_strings":["Dept. of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico"],"raw_orcid":"https://orcid.org/0000-0003-2075-8313","affiliations":[{"raw_affiliation_string":"Dept. of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","institution_ids":["https://openalex.org/I68368234"]},{"raw_affiliation_string":"Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","institution_ids":["https://openalex.org/I68368234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036829463","display_name":"Diana Laura Silva\u2010Velasco","orcid":"https://orcid.org/0000-0003-1064-4371","observed_orcids":["https://orcid.org/0000-0003-1064-4371"]},"institutions":[{"id":"https://openalex.org/I68368234","display_name":"Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/009eqmr18","country_code":"MX","type":"facility","lineage":["https://openalex.org/I59361560","https://openalex.org/I68368234"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Diana L. Silva-Velasco","raw_affiliation_strings":["Dept. of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico"],"raw_orcid":"https://orcid.org/0000-0003-1064-4371","affiliations":[{"raw_affiliation_string":"Dept. of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","institution_ids":["https://openalex.org/I68368234"]},{"raw_affiliation_string":"Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","institution_ids":["https://openalex.org/I68368234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101413005","display_name":"Ning Xia","orcid":"https://orcid.org/0000-0002-5553-1752","observed_orcids":["https://orcid.org/0000-0002-5553-1752"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ning Xia","raw_affiliation_strings":["Dept. of Pharmacology, Johannes Gutenberg University, Mainz, Germany","Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany"],"raw_orcid":"https://orcid.org/0000-0002-5553-1752","affiliations":[{"raw_affiliation_string":"Dept. of Pharmacology, Johannes Gutenberg University, Mainz, Germany","institution_ids":["https://openalex.org/I197323543"]},{"raw_affiliation_string":"Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany","institution_ids":["https://openalex.org/I197323543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047123077","display_name":"Aimo Kannt","orcid":"https://orcid.org/0000-0002-5197-2286","observed_orcids":["https://orcid.org/0000-0002-5197-2286"]},"institutions":[{"id":"https://openalex.org/I4210107844","display_name":"Fraunhofer Institute for Translational Medicine and Pharmacology","ror":"https://ror.org/01s1h3j07","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210107844","https://openalex.org/I4923324"]},{"id":"https://openalex.org/I4210138838","display_name":"Sanofi (Germany)","ror":"https://ror.org/03ytdtb31","country_code":"DE","type":"company","lineage":["https://openalex.org/I3018075036","https://openalex.org/I4210138838"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Aimo Kannt","raw_affiliation_strings":["Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt, Germany","Sanofi Research and Development, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210107844"]},{"raw_affiliation_string":"Sanofi Research and Development, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210138838"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021683292","display_name":"Urs Christen","orcid":"https://orcid.org/0000-0003-4165-7976","observed_orcids":["https://orcid.org/0000-0003-4165-7976"]},"institutions":[{"id":"https://openalex.org/I114090438","display_name":"Goethe University Frankfurt","ror":"https://ror.org/04cvxnb49","country_code":"DE","type":"education","lineage":["https://openalex.org/I114090438"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Urs Christen","raw_affiliation_strings":["Pharmazentrum, Goethe University, Frankfurt, Germany"],"raw_orcid":"https://orcid.org/0000-0003-4165-7976","affiliations":[{"raw_affiliation_string":"Pharmazentrum, Goethe University, Frankfurt, Germany","institution_ids":["https://openalex.org/I114090438"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009177573","display_name":"David Centuri\u00f3n","orcid":"https://orcid.org/0000-0003-4030-8491","observed_orcids":["https://orcid.org/0000-0003-4030-8491"]},"institutions":[{"id":"https://openalex.org/I68368234","display_name":"Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/009eqmr18","country_code":"MX","type":"facility","lineage":["https://openalex.org/I59361560","https://openalex.org/I68368234"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"David Centurion","raw_affiliation_strings":["Dept. of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico"],"raw_orcid":"https://orcid.org/0000-0003-4030-8491","affiliations":[{"raw_affiliation_string":"Dept. of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","institution_ids":["https://openalex.org/I68368234"]},{"raw_affiliation_string":"Department of Pharmacobiology, Cinvestav IPN, Mexico City, Mexico","institution_ids":["https://openalex.org/I68368234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064206049","display_name":"Huige Li","orcid":"https://orcid.org/0000-0003-3458-7391","observed_orcids":["https://orcid.org/0000-0003-3458-7391"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Huige Li","raw_affiliation_strings":["Dept. of Pharmacology, Johannes Gutenberg University, Mainz, Germany","Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany"],"raw_orcid":"https://orcid.org/0000-0003-3458-7391","affiliations":[{"raw_affiliation_string":"Dept. of Pharmacology, Johannes Gutenberg University, Mainz, Germany","institution_ids":["https://openalex.org/I197323543"]},{"raw_affiliation_string":"Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany","institution_ids":["https://openalex.org/I197323543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080433113","display_name":"Andrea Pautz","orcid":"https://orcid.org/0000-0003-3969-0056","observed_orcids":["https://orcid.org/0000-0003-3969-0056"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andrea Pautz","raw_affiliation_strings":["Dept. of Pharmacology, Johannes Gutenberg University, Mainz, Germany","Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pharmacology, Johannes Gutenberg University, Mainz, Germany","institution_ids":["https://openalex.org/I197323543"]},{"raw_affiliation_string":"Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany","institution_ids":["https://openalex.org/I197323543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014931781","display_name":"Ebru Arioglu\u2010Inan","orcid":"https://orcid.org/0000-0002-0860-0815","observed_orcids":["https://orcid.org/0000-0002-0860-0815"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ebru Arioglu-Inan","raw_affiliation_strings":["Dept. of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey","Department of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey"],"raw_orcid":"https://orcid.org/0000-0002-0860-0815","affiliations":[{"raw_affiliation_string":"Dept. of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]},{"raw_affiliation_string":"Department of Pharmacology, School of Pharmacy, Ankara University, Ankara, Turkey","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040869371","display_name":"Martin Christian Michel","orcid":"https://orcid.org/0000-0003-4161-8467","observed_orcids":["https://orcid.org/0000-0003-4161-8467"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Martin C. Michel","raw_affiliation_strings":["Dept. of Pharmacology, Johannes Gutenberg University, Mainz, Germany","Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany"],"raw_orcid":"https://orcid.org/0000-0003-4161-8467","affiliations":[{"raw_affiliation_string":"Dept. of Pharmacology, Johannes Gutenberg University, Mainz, Germany","institution_ids":["https://openalex.org/I197323543"]},{"raw_affiliation_string":"Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany","institution_ids":["https://openalex.org/I197323543"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5040869371"],"corresponding_institution_ids":["https://openalex.org/I197323543"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":3116,"currency":"EUR","value_usd":3360},"fwci":2.0386,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.85183542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"13","issue":null,"first_page":"923555","last_page":"923555"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.8999999761581421},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9850000143051147},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.9430000185966492},{"id":"https://openalex.org/keywords/fructose-feeding","display_name":"fructose feeding","score":0.6660000085830688},{"id":"https://openalex.org/keywords/db-db-mice","display_name":"db/db mice","score":0.9789999723434448},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9520000219345093},{"id":"https://openalex.org/keywords/blood-glucose","display_name":"blood glucose","score":0.7940000295639038},{"id":"https://openalex.org/keywords/glycosuria","display_name":"glycosuria","score":0.8489999771118164},{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.871999979019165},{"id":"https://openalex.org/keywords/elafibranor","display_name":"elafibranor","score":0.8970000147819519},{"id":"https://openalex.org/keywords/empagliflozin","display_name":"empagliflozin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/linagliptin","display_name":"linagliptin","score":0.9950000047683716},{"id":"https://openalex.org/keywords/semaglutide","display_name":"semaglutide","score":0.9819999933242798}],"concepts":[{"id":"https://openalex.org/C2780180277","wikidata":"https://www.wikidata.org/wiki/Q1124286","display_name":"Polyuria","level":3,"score":0.9329478740692139},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6998252868652344},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6460241675376892},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.617236852645874},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5953783988952637},{"id":"https://openalex.org/C2781214132","wikidata":"https://www.wikidata.org/wiki/Q1136213","display_name":"Glycosuria","level":3,"score":0.5915094017982483},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.5712525844573975},{"id":"https://openalex.org/C2779762690","wikidata":"https://www.wikidata.org/wiki/Q9382","display_name":"Urinary bladder","level":2,"score":0.5105932354927063},{"id":"https://openalex.org/C2779624480","wikidata":"https://www.wikidata.org/wiki/Q635195","display_name":"Polydipsia","level":3,"score":0.45305150747299194},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.424099862575531},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.42338261008262634}],"mesh":[],"locations_count":10,"locations":[{"id":"doi:10.3389/fphys.2022.923555","doi":"https://doi.org/10.3389/fphys.2022.923555","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2022.923555","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2022.923555/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},{"id":"doi:10.1101/2021.10.25.465601","doi":"https://doi.org/10.1101/2021.10.25.465601","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.10.25.465601","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2021/10/26/2021.10.25.465601.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:36003651","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36003651","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in physiology","raw_type":"Journal Article"},{"id":"pmh:oai:USBKOELN.ub.uni-koeln.de:68710","doi":null,"is_oa":false,"landing_page_url":"https://kups.ub.uni-koeln.de/68710/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400371","display_name":"K\u00f6lner Universit\u00e4ts PublikationsServer (Universit\u00e4t zu K\u00f6ln)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115942","host_organization_name":"Rhenish Institute for Environmental Research","host_organization_lineage":["https://openalex.org/I4210115942"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"doc-type:article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9393211","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9393211/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Physiol","raw_type":"Text"},{"id":"pmh:oai:openscience.ub.uni-mainz.de:20.500.12030/8621","doi":null,"is_oa":true,"landing_page_url":"https://openscience.ub.uni-mainz.de/handle/20.500.12030/8621","pdf_url":"http://openscience.ub.uni-mainz.de/bitstreams/4b40e457-de67-415f-ba6c-7d016d518bb8/download","source":{"id":"https://openalex.org/S7407055239","display_name":"Gutenberg Open Science","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in physiology. 13. -. 2022. -. -. 923555","raw_type":"publishedVersion"},{"id":"pmh:oai:doaj.org/article:f59087392e074b2ea5f40362b866547a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f59087392e074b2ea5f40362b866547a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Physiology, Vol 13 (2022)","raw_type":"article"},{"id":"pmh:oai:publica.fraunhofer.de:publica/442403","doi":null,"is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/442403","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:publikationen.ub.uni-frankfurt.de:90639","doi":null,"is_oa":true,"landing_page_url":"https://nbn-resolving.org/urn:nbn:de:hebis:30:3-906399","pdf_url":null,"source":{"id":"https://openalex.org/S4306400432","display_name":"Publication Server of Goethe University Frankfurt am Main (Goethe University Frankfurt)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114090438","host_organization_name":"Goethe University Frankfurt","host_organization_lineage":["https://openalex.org/I114090438"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"doi:10.25358/openscience-8605","doi":"https://doi.org/10.25358/openscience-8605","is_oa":true,"landing_page_url":"https://doi.org/10.25358/openscience-8605","pdf_url":null,"source":{"id":"https://openalex.org/S7407055239","display_name":"Gutenberg Open Science","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.3389/fphys.2022.923555","doi":"https://doi.org/10.3389/fphys.2022.923555","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2022.923555","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2022.923555/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[{"id":"https://openalex.org/G2482229364","display_name":null,"funder_award_id":"LI-1042/5-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G2615822639","display_name":null,"funder_award_id":"XI 139/2-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G6189093479","display_name":null,"funder_award_id":"294/10","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G625756131","display_name":null,"funder_award_id":"Mi 294-10/1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320307781","display_name":"Sanofi","ror":"https://ror.org/027vj4x92"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320331259","display_name":"LOEWE-Zentrum f\u00fcr Translationale Medizin und Pharmakologie","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4290565880.pdf","grobid_xml":"https://content.openalex.org/works/W4290565880.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W20782350","https://openalex.org/W1593555249","https://openalex.org/W1697523131","https://openalex.org/W1894104094","https://openalex.org/W1968823108","https://openalex.org/W1969093324","https://openalex.org/W1983498402","https://openalex.org/W1993480354","https://openalex.org/W2014718725","https://openalex.org/W2020355934","https://openalex.org/W2029439026","https://openalex.org/W2034265241","https://openalex.org/W2038775868","https://openalex.org/W2042430887","https://openalex.org/W2063071175","https://openalex.org/W2084618648","https://openalex.org/W2098138696","https://openalex.org/W2107701127","https://openalex.org/W2110240525","https://openalex.org/W2115739289","https://openalex.org/W2135520747","https://openalex.org/W2136705287","https://openalex.org/W2142032747","https://openalex.org/W2162140339","https://openalex.org/W2165527160","https://openalex.org/W2398149172","https://openalex.org/W2531325010","https://openalex.org/W2576869859","https://openalex.org/W2605041933","https://openalex.org/W2736085824","https://openalex.org/W2793351641","https://openalex.org/W2889056978","https://openalex.org/W2906967419","https://openalex.org/W2964162527","https://openalex.org/W2997946065","https://openalex.org/W3016460579","https://openalex.org/W3034291877","https://openalex.org/W3047879827","https://openalex.org/W3081422974","https://openalex.org/W3150345548","https://openalex.org/W3177380319","https://openalex.org/W3192747788","https://openalex.org/W4233435953","https://openalex.org/W4237098437"],"related_works":["https://openalex.org/W3209823399","https://openalex.org/W4225389572","https://openalex.org/W3018921096","https://openalex.org/W2889056978","https://openalex.org/W2242999045","https://openalex.org/W2793351641","https://openalex.org/W2964162527","https://openalex.org/W4321375786","https://openalex.org/W6910212156","https://openalex.org/W4396849820"],"abstract_inverted_index":{"The":[0],"urinary":[1],"bladder":[2,44,70,96,102,118,209,229,249],"is":[3,251],"markedly":[4,232],"enlarged":[5],"in":[6,120,128,142],"the":[7,20,40,105,111,224,246],"type":[8,31,63,237],"1":[9],"diabetes":[10,58,234,239],"mellitus":[11],"model":[12],"of":[13,30,57,62,144,180,228],"streptozotocin-injected":[14],"rats,":[15,130],"which":[16],"may":[17],"contribute":[18],"to":[19,173,191,193],"frequent":[21],"diabetic":[22,161],"uropathy.":[23],"Much":[24],"less":[25],"data":[26,68,115,182,242],"exists":[27],"for":[28,95,99,160,176],"models":[29,56,61],"2":[32,64,238],"diabetes.":[33],"Diabetic":[34],"polyuria":[35,162],"has":[36],"been":[37],"proposed":[38],"as":[39,157],"pathophysiological":[41],"mechanism":[42],"behind":[43],"enlargement.":[45],"Therefore,":[46],"we":[47],"explored":[48],"such":[49],"a":[50,136,158,194],"relationship":[51],"across":[52,233],"nine":[53],"distinct":[54],"rodent":[55],"including":[59],"seven":[60],"diabetes/obesity":[65],"by":[66,254],"collecting":[67],"on":[69,104,110,135,208,218],"weight":[71,103,151,210],"and":[72,98,107,123,133,199,226],"blood":[73,155],"glucose":[74,108,156,219,255],"from":[75,183],"16":[76],"studies":[77,83,185],"with":[78,86,154],"2\u20138":[79],"arms":[80,85],"each;":[81],"some":[82,143,164],"included":[84],"various":[87],"diets":[88,198],"and/or":[89],"pharmacological":[90],"treatments.":[91],"Data":[92],"were":[93,171],"analysed":[94],"enlargement":[97,119,127,139,230,250],"correlations":[100,170],"between":[101],"one":[106],"levels":[109,188],"other":[112,167],"hand.":[113],"Our":[114],"confirm":[116],"major":[117],"streptozotocin":[121],"rats":[122],"minor":[124],"if":[125],"any":[126],"fructose-fed":[129],"db/db":[131],"mice":[132,134,178],"high-fat":[137],"diet;":[138],"was":[140,152],"present":[141],"five":[145],"not":[146,166,214,244],"reported":[147],"previously":[148],"models.":[149],"Bladder":[150],"correlated":[153],"proxy":[159],"within":[163],"but":[165,169],"models,":[168,235],"moderate":[172],"weak":[174],"except":[175],"RIP-LCMV":[177],"(r2":[179],"pooled":[181],"all":[184],"0.0621).":[186],"Insulin":[187],"also":[189],"failed":[190],"correlate":[192],"meaningful":[195],"extent.":[196],"Various":[197],"medications":[200],"(elafibranor,":[201],"empagliflozin,":[202],"linagliptin,":[203],"semaglutide)":[204],"had":[205],"heterogeneous":[206],"effects":[207,217],"that":[211,223,248],"often":[212],"did":[213],"match":[215],"their":[216],"levels.":[220],"We":[221],"conclude":[222],"presence":[225],"extent":[227],"vary":[231],"particularly":[236],"models;":[240],"our":[241],"do":[243],"support":[245],"idea":[247],"primarily":[252],"driven":[253],"levels/glucosuria.":[256]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2022-08-08T00:00:00"}