{"id":"https://openalex.org/W4290465613","doi":"https://doi.org/10.1007/978-3-030-95975-3_8","title":"The Effects of Hemoglobin-Based Oxygen Carriers (HBOC) on the Microcirculation","display_name":"The Effects of Hemoglobin-Based Oxygen Carriers (HBOC) on the Microcirculation","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4290465613","doi":"https://doi.org/10.1007/978-3-030-95975-3_8"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-030-95975-3_8","doi":"https://doi.org/10.1007/978-3-030-95975-3_8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-030-95975-3_8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Substitutes and Oxygen Biotherapeutics","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4290465643","display_name":"Blood Substitutes and Oxygen Biotherapeutics"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108610073","display_name":"Anthony Cheung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony T. W. Cheung","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, University of California, Davis School of Medicine, Sacramento, CA, USA","Institute for Biomedical Sciences, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, University of California, Davis School of Medicine, Sacramento, CA, USA","institution_ids":["https://openalex.org/I4210160527","https://openalex.org/I84218800"]},{"raw_affiliation_string":"Institute for Biomedical Sciences, San Diego, CA, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017988774","display_name":"Peter C. Y. Chen","orcid":"https://orcid.org/0000-0003-4851-9875","observed_orcids":["https://orcid.org/0000-0003-4851-9875"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter C. Y. Chen","raw_affiliation_strings":["Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA","Institute for Biomedical Sciences, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute for Biomedical Sciences, San Diego, CA, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.29508197,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"81","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.7958999872207642,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.7958999872207642,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.11490000039339066,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.05950000137090683,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemoglobin-based-oxygen-carriers","display_name":"hemoglobin-based oxygen carriers","score":1.0},{"id":"https://openalex.org/keywords/microcirculation","display_name":"microcirculation","score":0.8619999885559082},{"id":"https://openalex.org/keywords/hemorrhagic-shock","display_name":"hemorrhagic shock","score":0.9950000047683716},{"id":"https://openalex.org/keywords/blood-substitutes","display_name":"blood substitutes","score":0.8119999766349792},{"id":"https://openalex.org/keywords/conjunctival-microvasculature","display_name":"conjunctival microvasculature","score":0.8529999852180481},{"id":"https://openalex.org/keywords/exchange-transfusion","display_name":"exchange transfusion","score":0.7089999914169312},{"id":"https://openalex.org/keywords/golden-hour","display_name":"golden hour","score":0.5529999732971191}],"concepts":[{"id":"https://openalex.org/C12722491","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microcirculation","level":2,"score":0.811833381652832},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7165185213088989},{"id":"https://openalex.org/C2781300812","wikidata":"https://www.wikidata.org/wiki/Q178061","display_name":"Shock (circulatory)","level":2,"score":0.6160153746604919},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.5544214844703674},{"id":"https://openalex.org/C2778165595","wikidata":"https://www.wikidata.org/wiki/Q5491454","display_name":"Resuscitation","level":2,"score":0.5085684061050415},{"id":"https://openalex.org/C2779042277","wikidata":"https://www.wikidata.org/wiki/Q886468","display_name":"Exchange transfusion","level":2,"score":0.4603772759437561},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.4565720856189728},{"id":"https://openalex.org/C2778337571","wikidata":"https://www.wikidata.org/wiki/Q831050","display_name":"Blood substitute","level":3,"score":0.44748884439468384},{"id":"https://openalex.org/C2993864201","wikidata":"https://www.wikidata.org/wiki/Q7873","display_name":"Oxygen transport","level":3,"score":0.4197947382926941},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.4186282157897949},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.35324910283088684},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3377193212509155},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.33638086915016174},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3029639720916748},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.15520384907722473},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08754029870033264},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-030-95975-3_8","doi":"https://doi.org/10.1007/978-3-030-95975-3_8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-030-95975-3_8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Substitutes and Oxygen Biotherapeutics","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation","score":0.5199999809265137}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W743009","https://openalex.org/W79602083","https://openalex.org/W158373390","https://openalex.org/W315747309","https://openalex.org/W1680436208","https://openalex.org/W1705726808","https://openalex.org/W1843823988","https://openalex.org/W1911659939","https://openalex.org/W1974141222","https://openalex.org/W1975499875","https://openalex.org/W1979767166","https://openalex.org/W1994746923","https://openalex.org/W2002633669","https://openalex.org/W2003555632","https://openalex.org/W2008452465","https://openalex.org/W2030662193","https://openalex.org/W2040854851","https://openalex.org/W2046025881","https://openalex.org/W2047025675","https://openalex.org/W2048961900","https://openalex.org/W2052374392","https://openalex.org/W2058080945","https://openalex.org/W2095001699","https://openalex.org/W2098500744","https://openalex.org/W2112839328","https://openalex.org/W2129162517","https://openalex.org/W2168715128","https://openalex.org/W2201312145","https://openalex.org/W2313871166","https://openalex.org/W2319483832","https://openalex.org/W2585644329","https://openalex.org/W2903636545","https://openalex.org/W3016542639","https://openalex.org/W3021135153","https://openalex.org/W3095923992","https://openalex.org/W4242107281","https://openalex.org/W4249877159"],"related_works":["https://openalex.org/W4398165117","https://openalex.org/W1508313776","https://openalex.org/W2461848154","https://openalex.org/W2040675720","https://openalex.org/W7167832937","https://openalex.org/W3095923992","https://openalex.org/W1973370166","https://openalex.org/W2519532907","https://openalex.org/W1975907370","https://openalex.org/W2118390662"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2022-08-08T00:00:00"}