{"id":"https://openalex.org/W4290341902","doi":null,"title":"Gadolinium-Based Nanoparticles and Radiation Therapy for Multiple Brain Melanoma Metastases and brain tumors: from bench to beside.","display_name":"Gadolinium-Based Nanoparticles and Radiation Therapy for Multiple Brain Melanoma Metastases and brain tumors: from bench to beside.","publication_year":2016,"publication_date":"2016-03-08","ids":{"openalex":"https://openalex.org/W4290341902"},"language":"en","primary_location":{"id":"pmh:oai:HAL:hal-01275100v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-01275100","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"11th annual meeting of the European Society for Molecular Imaging (ESMI) - European Molecular Imaging Meeting (EMIM), Mar 2016, Utrecht, Netherlands","raw_type":"info:eu-repo/semantics/conferenceObject"},"volume":null,"type":"conference-paper","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041930080","display_name":"Lucie Sancey","orcid":"https://orcid.org/0000-0002-0084-3775","observed_orcids":["https://orcid.org/0000-0002-0084-3775"]},"institutions":[{"id":"https://openalex.org/I4210133140","display_name":"Institut Lumi\u00e8re Mati\u00e8re","ror":"https://ror.org/0323bey33","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I112936343","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210098836","https://openalex.org/I4210133140","https://openalex.org/I4405259976","https://openalex.org/I4405263940","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sancey, Lucie","raw_affiliation_strings":["Institut Lumi\u00e8re Mati\u00e8re [Villeurbanne]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Lumi\u00e8re Mati\u00e8re [Villeurbanne]","institution_ids":["https://openalex.org/I4210133140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061448446","display_name":"Shady Kotb","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133140","display_name":"Institut Lumi\u00e8re Mati\u00e8re","ror":"https://ror.org/0323bey33","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I112936343","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210098836","https://openalex.org/I4210133140","https://openalex.org/I4405259976","https://openalex.org/I4405263940","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Kotb, Shady","raw_affiliation_strings":["Institut Lumi\u00e8re Mati\u00e8re [Villeurbanne]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Lumi\u00e8re Mati\u00e8re [Villeurbanne]","institution_ids":["https://openalex.org/I4210133140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052444841","display_name":"Sandrine Dufort","orcid":"https://orcid.org/0000-0003-1624-247X","observed_orcids":["https://orcid.org/0000-0003-1624-247X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dufort, Sandrine","raw_affiliation_strings":["NH TherAguix SA [Meylan]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NH TherAguix SA [Meylan]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043706856","display_name":"Fran\u00e7ois Lux","orcid":"https://orcid.org/0000-0003-1568-0240","observed_orcids":["https://orcid.org/0000-0003-1568-0240"]},"institutions":[{"id":"https://openalex.org/I4210133140","display_name":"Institut Lumi\u00e8re Mati\u00e8re","ror":"https://ror.org/0323bey33","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I112936343","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210098836","https://openalex.org/I4210133140","https://openalex.org/I4405259976","https://openalex.org/I4405263940","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Lux, Fran\u00e7ois","raw_affiliation_strings":["Institut Lumi\u00e8re Mati\u00e8re [Villeurbanne]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Lumi\u00e8re Mati\u00e8re [Villeurbanne]","institution_ids":["https://openalex.org/I4210133140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071314071","display_name":"Camille Verry","orcid":"https://orcid.org/0000-0002-9362-7624","observed_orcids":["https://orcid.org/0000-0002-9362-7624"]},"institutions":[{"id":"https://openalex.org/I899635006","display_name":"Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/02rx3b187","country_code":"FR","type":"education","lineage":["https://openalex.org/I899635006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Verry, Camille","raw_affiliation_strings":["Universit\u00e9 Grenoble Alpes - UFR M\u00e9decine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Grenoble Alpes - UFR M\u00e9decine","institution_ids":["https://openalex.org/I899635006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008751102","display_name":"G\u00e9raldine Le Duc","orcid":"https://orcid.org/0000-0003-2724-6847","observed_orcids":["https://orcid.org/0000-0003-2724-6847"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Le Duc, G\u00e9raldine","raw_affiliation_strings":["NH TherAguix SA [Meylan]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NH TherAguix SA [Meylan]","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105990096","display_name":"Olivier Tillement","orcid":"https://orcid.org/0000-0001-7166-6537","observed_orcids":["https://orcid.org/0000-0001-7166-6537"]},"institutions":[{"id":"https://openalex.org/I4210133140","display_name":"Institut Lumi\u00e8re Mati\u00e8re","ror":"https://ror.org/0323bey33","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I112936343","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210098836","https://openalex.org/I4210133140","https://openalex.org/I4405259976","https://openalex.org/I4405263940","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Tillement, Olivier","raw_affiliation_strings":["Institut Lumi\u00e8re Mati\u00e8re [Villeurbanne]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Lumi\u00e8re Mati\u00e8re [Villeurbanne]","institution_ids":["https://openalex.org/I4210133140"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.45340357,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.8140000104904175,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.8140000104904175,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.057500001043081284,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.0340999998152256,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gadolinium-based-nanoparticles","display_name":"gadolinium-based nanoparticles","score":0.8970000147819519},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.8270000219345093},{"id":"https://openalex.org/keywords/brain-metastases","display_name":"brain metastases","score":0.8880000114440918},{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.7480000257492065},{"id":"https://openalex.org/keywords/brain-tumors","display_name":"brain tumors","score":0.9750000238418579},{"id":"https://openalex.org/keywords/magnetic-nanoparticles","display_name":"magnetic nanoparticles","score":0.4449999928474426},{"id":"https://openalex.org/keywords/hyperthermia","display_name":"hyperthermia","score":0.5759999752044678},{"id":"https://openalex.org/keywords/translational-research","display_name":"translational research","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.666079044342041},{"id":"https://openalex.org/C3020000666","wikidata":"https://www.wikidata.org/wiki/Q17112037","display_name":"Bench to bedside","level":2,"score":0.6428555846214294},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.5474562644958496},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5084373354911804},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.32253849506378174},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3023611307144165},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.21401625871658325}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:HAL:hal-01275100v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-01275100","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"11th annual meeting of the European Society for Molecular Imaging (ESMI) - European Molecular Imaging Meeting (EMIM), Mar 2016, Utrecht, Netherlands","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4293509840","https://openalex.org/W2279343446","https://openalex.org/W2138229891","https://openalex.org/W4414557897","https://openalex.org/W2526718839","https://openalex.org/W1966768237","https://openalex.org/W3042444813","https://openalex.org/W2289937994","https://openalex.org/W1982913214","https://openalex.org/W3134065093"],"abstract_inverted_index":{"More":[0],"than":[1],"half":[2],"of":[3,24,59],"all":[4],"clinical":[5],"cancer":[6],"patients":[7],"undergo":[8],"radiation":[9,26],"therapy.":[10],"Besides":[11],"the":[12,22,35,54],"poor":[13],"prognosis":[14],"for":[15,53],"multiple":[16],"brain":[17,20,60],"metastases":[18],"and":[19,50,57],"tumors,":[21],"delivery":[23],"curative":[25],"dose":[27],"to":[28],"induce":[29],"tumor-kill":[30],"is":[31],"strongly":[32],"restricted":[33],"by":[34],"healthy":[36],"proximal":[37],"brain.":[38],"We":[39],"describe":[40],"a":[41],"nanoparticle":[42],"which":[43],"can":[44],"act":[45],"as":[46],"MR":[47],"contrast":[48],"agent":[49],"radiosensitizer":[51],"concomitantly,":[52],"detection,":[55],"monitoring":[56],"treatment":[58],"cancers.":[61]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-08-07T00:00:00"}