{"id":"https://openalex.org/W4289948273","doi":"https://doi.org/10.1111/mmi.14969","title":"Roles of RodZ and class A PBP1b in the assembly and regulation of the peripheral peptidoglycan elongasome in ovoid\u2010shaped cells of Streptococcus pneumoniae D39","display_name":"Roles of RodZ and class A PBP1b in the assembly and regulation of the peripheral peptidoglycan elongasome in ovoid\u2010shaped cells of Streptococcus pneumoniae D39","publication_year":2022,"publication_date":"2022-08-05","ids":{"openalex":"https://openalex.org/W4289948273","doi":"https://doi.org/10.1111/mmi.14969","pmid":"https://pubmed.ncbi.nlm.nih.gov/36001060","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9804626"},"language":"en","primary_location":{"id":"doi:10.1111/mmi.14969","doi":"https://doi.org/10.1111/mmi.14969","is_oa":true,"landing_page_url":"https://doi.org/10.1111/mmi.14969","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mmi.14969","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mmi.14969","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010616100","display_name":"Melissa M. Lamanna","orcid":"https://orcid.org/0000-0002-6535-7903","observed_orcids":["https://orcid.org/0000-0002-6535-7903"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa M. Lamanna","raw_affiliation_strings":["Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA"],"raw_orcid":"https://orcid.org/0000-0002-6535-7903","affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001078286","display_name":"Irfan Manzoor","orcid":"https://orcid.org/0000-0003-3850-2690","observed_orcids":["https://orcid.org/0000-0003-3850-2690"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Irfan Manzoor","raw_affiliation_strings":["Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041052738","display_name":"Merrin Joseph","orcid":"https://orcid.org/0000-0002-0943-920X","observed_orcids":["https://orcid.org/0000-0002-0943-920X"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Merrin Joseph","raw_affiliation_strings":["Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061342141","display_name":"Ziyun A. Ye","orcid":"https://orcid.org/0009-0007-5819-6957","observed_orcids":["https://orcid.org/0009-0007-5819-6957"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ziyun A. Ye","raw_affiliation_strings":["Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054725527","display_name":"Mattia Benedet","orcid":"https://orcid.org/0000-0001-7086-796X","observed_orcids":["https://orcid.org/0000-0001-7086-796X","https://orcid.org/0009-0001-5860-4128"]},"institutions":[{"id":"https://openalex.org/I193223587","display_name":"University of Trento","ror":"https://ror.org/05trd4x28","country_code":"IT","type":"education","lineage":["https://openalex.org/I193223587"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mattia Benedet","raw_affiliation_strings":["Department Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Italy","Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Italy","institution_ids":["https://openalex.org/I193223587"]},{"raw_affiliation_string":"Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy","institution_ids":["https://openalex.org/I193223587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046525714","display_name":"Alessia Zanardi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193223587","display_name":"University of Trento","ror":"https://ror.org/05trd4x28","country_code":"IT","type":"education","lineage":["https://openalex.org/I193223587"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessia Zanardi","raw_affiliation_strings":["Department Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Italy","Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Italy","institution_ids":["https://openalex.org/I193223587"]},{"raw_affiliation_string":"Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy","institution_ids":["https://openalex.org/I193223587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035309262","display_name":"Zhongqing Ren","orcid":"https://orcid.org/0000-0003-1788-5362","observed_orcids":["https://orcid.org/0000-0003-1788-5362"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhongqing Ren","raw_affiliation_strings":["Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA"],"raw_orcid":"https://orcid.org/0000-0003-1788-5362","affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076890039","display_name":"Xindan Wang","orcid":"https://orcid.org/0000-0001-6458-180X","observed_orcids":["https://orcid.org/0000-0001-6458-180X"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xindan Wang","raw_affiliation_strings":["Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA"],"raw_orcid":"https://orcid.org/0000-0001-6458-180X","affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069138882","display_name":"Orietta Massidda","orcid":"https://orcid.org/0000-0001-8823-2372","observed_orcids":["https://orcid.org/0000-0001-8823-2372"]},"institutions":[{"id":"https://openalex.org/I193223587","display_name":"University of Trento","ror":"https://ror.org/05trd4x28","country_code":"IT","type":"education","lineage":["https://openalex.org/I193223587"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Orietta Massidda","raw_affiliation_strings":["Department Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Italy","Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy"],"raw_orcid":"https://orcid.org/0000-0001-8823-2372","affiliations":[{"raw_affiliation_string":"Department Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Italy","institution_ids":["https://openalex.org/I193223587"]},{"raw_affiliation_string":"Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy","institution_ids":["https://openalex.org/I193223587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003577027","display_name":"Ho\u2010Ching Tiffany Tsui","orcid":"https://orcid.org/0000-0003-0849-874X","observed_orcids":["https://orcid.org/0000-0003-0849-874X"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ho-Ching T. Tsui","raw_affiliation_strings":["Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA"],"raw_orcid":"https://orcid.org/0000-0003-0849-874X","affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006090738","display_name":"Malcolm E. Winkler","orcid":"https://orcid.org/0000-0002-1482-2588","observed_orcids":["https://orcid.org/0000-0002-1482-2588"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Malcolm E. Winkler","raw_affiliation_strings":["Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA"],"raw_orcid":"https://orcid.org/0000-0002-1482-2588","affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, IN 47405 USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5003577027","https://openalex.org/A5006090738"],"corresponding_institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":{"value":3900,"currency":"USD","value_usd":3900},"fwci":1.9607,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.86395746,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"118","issue":"4","first_page":"336","last_page":"368"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rodz","display_name":"RodZ","score":0.9909999966621399},{"id":"https://openalex.org/keywords/class-a-penicillin-binding-proteins","display_name":"class A penicillin-binding proteins","score":0.6679999828338623},{"id":"https://openalex.org/keywords/pbp1b","display_name":"PBP1b","score":0.9079999923706055},{"id":"https://openalex.org/keywords/streptococcus-pneumoniae","display_name":"Streptococcus pneumoniae","score":0.9570000171661377},{"id":"https://openalex.org/keywords/mrec","display_name":"MreC","score":0.9419999718666077},{"id":"https://openalex.org/keywords/mreb","display_name":"MreB","score":0.7440000176429749},{"id":"https://openalex.org/keywords/cell-shape-regulation","display_name":"cell shape regulation","score":0.5389999747276306},{"id":"https://openalex.org/keywords/scaffold-proteins","display_name":"scaffold proteins","score":0.7509999871253967},{"id":"https://openalex.org/keywords/tn-seq","display_name":"Tn-seq","score":0.6570000052452087},{"id":"https://openalex.org/keywords/cell-division","display_name":"cell division","score":0.41499999165534973},{"id":"https://openalex.org/keywords/cell-wall-synthesis","display_name":"cell wall biosynthesis","score":0.3089999854564667}],"concepts":[{"id":"https://openalex.org/C62551211","wikidata":"https://www.wikidata.org/wiki/Q24779699","display_name":"MreB","level":4,"score":0.8637081384658813},{"id":"https://openalex.org/C2776634448","wikidata":"https://www.wikidata.org/wiki/Q206920","display_name":"Peptidoglycan","level":3,"score":0.8542375564575195},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6862363815307617},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.5445771813392639},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5419251918792725},{"id":"https://openalex.org/C2781253189","wikidata":"https://www.wikidata.org/wiki/Q221179","display_name":"Streptococcus pneumoniae","level":3,"score":0.4662795066833496},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4588713049888611},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4477267563343048},{"id":"https://openalex.org/C125235067","wikidata":"https://www.wikidata.org/wiki/Q128700","display_name":"Cell wall","level":2,"score":0.4451184868812561},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.37488746643066406},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19264984130859375},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.1799817979335785},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16490444540977478},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.09129104018211365}],"mesh":[{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002473","descriptor_name":"Cell Wall","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010457","descriptor_name":"Peptidoglycan","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013296","descriptor_name":"Streptococcus pneumoniae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013296","descriptor_name":"Streptococcus pneumoniae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1111/mmi.14969","doi":"https://doi.org/10.1111/mmi.14969","is_oa":true,"landing_page_url":"https://doi.org/10.1111/mmi.14969","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mmi.14969","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},{"id":"doi:10.1101/2022.06.01.494439","doi":"https://doi.org/10.1101/2022.06.01.494439","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2022.06.01.494439","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2022/06/02/2022.06.01.494439.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:9804626","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9804626","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Microbiol","raw_type":"Text"},{"id":"pmid:36001060","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36001060","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unitn.it:11572/359801","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11572/359801","pdf_url":null,"source":{"id":"https://openalex.org/S4377196320","display_name":"Iris (University of Trento)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193223587","host_organization_name":"University of Trento","host_organization_lineage":["https://openalex.org/I193223587"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unitn.it:11572/486430","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11572/486430","pdf_url":null,"source":{"id":"https://openalex.org/S4377196320","display_name":"Iris (University of Trento)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193223587","host_organization_name":"University of Trento","host_organization_lineage":["https://openalex.org/I193223587"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1111/mmi.14969","doi":"https://doi.org/10.1111/mmi.14969","is_oa":true,"landing_page_url":"https://doi.org/10.1111/mmi.14969","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mmi.14969","source":{"id":"https://openalex.org/S102549058","display_name":"Molecular Microbiology","issn_l":"0950-382X","issn":["0950-382X","1365-2958"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4100860355","display_name":"Acquisition of a DeltaVision OMX-SR Imaging System","funder_award_id":"1s10od024988-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4633274091","display_name":null,"funder_award_id":"R01GM141242","funder_id":"https://openalex.org/F4320337349","funder_display_name":"NIH Office of the Director"},{"id":"https://openalex.org/G65590025","display_name":"Investigation of the essential, conserved RodZ protein in peptidoglycan synthesis in the ovococcal pathogen, Streptococcus pneumoniae","funder_award_id":"F31AI138430","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7366719298","display_name":null,"funder_award_id":"S10OD024988","funder_id":"https://openalex.org/F4320337349","funder_display_name":"NIH Office of the Director"},{"id":"https://openalex.org/G9000878258","display_name":"How bacterial SMC complexes organize chromosomes","funder_award_id":"R01GM141242","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000886445","display_name":"Dynamics and Regulation of Peptidoglycan Cell Wall Synthesis in the Superbug Streptococcus pneumoniae","funder_award_id":"R35GM131767","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320308357","display_name":"Boston College","ror":"https://ror.org/02n2fzt79"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332953","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56"},{"id":"https://openalex.org/F4320337349","display_name":"NIH Office of the Director","ror":"https://ror.org/00fj8a872"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4289948273.pdf","grobid_xml":"https://content.openalex.org/works/W4289948273.grobid-xml"},"referenced_works_count":119,"referenced_works":["https://openalex.org/W1138761191","https://openalex.org/W1493403505","https://openalex.org/W1570464651","https://openalex.org/W1608630924","https://openalex.org/W1923615078","https://openalex.org/W1934738351","https://openalex.org/W1966045566","https://openalex.org/W1966425369","https://openalex.org/W1970005524","https://openalex.org/W1973383826","https://openalex.org/W1974387686","https://openalex.org/W1978099519","https://openalex.org/W2001652739","https://openalex.org/W2002020281","https://openalex.org/W2004457291","https://openalex.org/W2008722826","https://openalex.org/W2012251902","https://openalex.org/W2014013498","https://openalex.org/W2015851444","https://openalex.org/W2031174158","https://openalex.org/W2032293502","https://openalex.org/W2038140390","https://openalex.org/W2040748781","https://openalex.org/W2044064599","https://openalex.org/W2055079545","https://openalex.org/W2057563851","https://openalex.org/W2058858340","https://openalex.org/W2062369911","https://openalex.org/W2072872900","https://openalex.org/W2090406897","https://openalex.org/W2093529725","https://openalex.org/W2105875485","https://openalex.org/W2113887801","https://openalex.org/W2116087032","https://openalex.org/W2116218627","https://openalex.org/W2116857869","https://openalex.org/W2122604859","https://openalex.org/W2122784613","https://openalex.org/W2131324249","https://openalex.org/W2131877044","https://openalex.org/W2133285842","https://openalex.org/W2136872913","https://openalex.org/W2137364135","https://openalex.org/W2137739481","https://openalex.org/W2144818300","https://openalex.org/W2146912013","https://openalex.org/W2147680302","https://openalex.org/W2148820099","https://openalex.org/W2150491437","https://openalex.org/W2151395519","https://openalex.org/W2152831222","https://openalex.org/W2153125716","https://openalex.org/W2154416798","https://openalex.org/W2171803733","https://openalex.org/W2275084756","https://openalex.org/W2296016243","https://openalex.org/W2346633051","https://openalex.org/W2463871935","https://openalex.org/W2467964007","https://openalex.org/W2517176893","https://openalex.org/W2521365029","https://openalex.org/W2529783938","https://openalex.org/W2538028411","https://openalex.org/W2555334316","https://openalex.org/W2563859344","https://openalex.org/W2564679034","https://openalex.org/W2589916349","https://openalex.org/W2613570472","https://openalex.org/W2734675315","https://openalex.org/W2759727025","https://openalex.org/W2785739339","https://openalex.org/W2788000426","https://openalex.org/W2789805902","https://openalex.org/W2794519236","https://openalex.org/W2794903445","https://openalex.org/W2795292973","https://openalex.org/W2822066044","https://openalex.org/W2892741125","https://openalex.org/W2895954140","https://openalex.org/W2903441342","https://openalex.org/W2911442910","https://openalex.org/W2911983544","https://openalex.org/W2943909183","https://openalex.org/W2950986463","https://openalex.org/W2953151969","https://openalex.org/W2966240922","https://openalex.org/W2987949480","https://openalex.org/W2997432935","https://openalex.org/W3008011595","https://openalex.org/W3008215279","https://openalex.org/W3011829967","https://openalex.org/W3012262711","https://openalex.org/W3013725920","https://openalex.org/W3024551994","https://openalex.org/W3035176777","https://openalex.org/W3049658440","https://openalex.org/W3082933488","https://openalex.org/W3091916107","https://openalex.org/W3109412353","https://openalex.org/W3128057403","https://openalex.org/W3128582586","https://openalex.org/W3129007696","https://openalex.org/W3133710833","https://openalex.org/W3134491518","https://openalex.org/W3149292653","https://openalex.org/W3157088446","https://openalex.org/W3160834851","https://openalex.org/W3177828909","https://openalex.org/W3188385885","https://openalex.org/W3198595154","https://openalex.org/W3202105508","https://openalex.org/W3206536423","https://openalex.org/W3211139963","https://openalex.org/W3213925490","https://openalex.org/W4200363183","https://openalex.org/W4200367884","https://openalex.org/W4220755026","https://openalex.org/W4242318543","https://openalex.org/W4289948273"],"related_works":["https://openalex.org/W7202193355","https://openalex.org/W7161545890","https://openalex.org/W4399667468","https://openalex.org/W3114674001","https://openalex.org/W3092227214","https://openalex.org/W2529783938","https://openalex.org/W7008812203","https://openalex.org/W2734675315","https://openalex.org/W2564679034","https://openalex.org/W4381053746"],"abstract_inverted_index":{"RodZ":[0,61,65],"of":[1,53,78,131,141],"rod-shaped":[2,67],"bacteria":[3],"functions":[4],"to":[5,9,20,64],"link":[6],"MreB":[7],"filaments":[8],"the":[10,21,51,73,116],"Rod":[11],"peptidoglycan":[12],"(PG)":[13],"synthase":[14],"complex":[15],"that":[16,37,48,72,96,151,170,184],"moves":[17],"circumferentially":[18],"perpendicular":[19],"long":[22],"cell":[23,117],"axis,":[24],"creating":[25],"hoop-like":[26],"sidewall":[27],"PG.":[28],"Ovoid-shaped":[29],"bacteria,":[30],"such":[31],"as":[32,173],"Streptococcus":[33],"pneumoniae":[34,58],"(pneumococcus;":[35],"Spn)":[36],"lack":[38],"MreB,":[39],"use":[40],"a":[41,60,104,157,174,189],"different":[42],"modality":[43],"for":[44,82,178],"peripheral":[45,196],"PG":[46,107,125,197],"elongation":[47],"emanates":[49],"from":[50],"midcell":[52],"dividing":[54],"cells.":[55],"Yet,":[56],"S.":[57],"encodes":[59],"homolog":[62],"similar":[63],"in":[66,106,134,191],"bacteria.":[68],"We":[69,168],"show":[70],"here":[71],"helix-turn-helix":[74],"and":[75,93,113,119,122,128,139,146,181,183,194],"transmembrane":[76],"domains":[77],"RodZ(Spn)":[79,109,132,171],"are":[80,88],"essential":[81],"growth":[83],"at":[84],"37\u00b0C.":[85],"\u0394rodZ":[86],"mutations":[87,95],"suppressed":[89],"by":[90],"\u0394pbp1a,":[91],"mpgA(Y488D),":[92],"\u0394khpA":[94],"suppress":[97],"\u0394mreC,":[98],"but":[99,153],"not":[100,154],"\u0394cozE.":[101],"Consistent":[102],"with":[103,111,124,162],"role":[105,190],"elongation,":[108],"co-localizes":[110],"MreC":[112],"aPBP1a":[114],"throughout":[115],"cycle":[118],"forms":[120],"complexes":[121],"interacts":[123],"elongasome":[126,142,179,192],"proteins":[127,143],"regulators.":[129],"Depletion":[130],"results":[133],"aberrantly":[135],"shaped,":[136],"non-growing":[137],"cells":[138],"mislocalization":[140],"MreC,":[144],"PBP2b,":[145],"RodA.":[147],"Moreover,":[148],"Tn-seq":[149],"reveals":[150],"RodZ(Spn),":[152],"MreCD(Spn),":[155],"displays":[156],"specific":[158],"synthetic-viable":[159],"genetic":[160],"relationship":[161],"aPBP1b,":[163,185],"whose":[164],"function":[165,182],"is":[166],"unknown.":[167],"conclude":[169],"acts":[172],"scaffolding":[175],"protein":[176],"required":[177],"assembly":[180],"like":[186],"aPBP1a,":[187],"plays":[188],"regulation":[193],"possibly":[195],"synthesis.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-08-06T00:00:00"}
