{"id":"https://openalex.org/W4289942232","doi":"https://doi.org/10.3389/fonc.2022.942943","title":"Correlation of dynamic contrast-enhanced MRI and diffusion-weighted MR imaging with prognostic factors and subtypes of breast cancers","display_name":"Correlation of dynamic contrast-enhanced MRI and diffusion-weighted MR imaging with prognostic factors and subtypes of breast cancers","publication_year":2022,"publication_date":"2022-08-05","ids":{"openalex":"https://openalex.org/W4289942232","doi":"https://doi.org/10.3389/fonc.2022.942943","pmid":"https://pubmed.ncbi.nlm.nih.gov/35992872","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9389013"},"language":"en","primary_location":{"id":"doi:10.3389/fonc.2022.942943","doi":"https://doi.org/10.3389/fonc.2022.942943","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2022.942943","pdf_url":"https://www.frontiersin.org/articles/10.3389/fonc.2022.942943/pdf","source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fonc.2022.942943/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107936571","display_name":"Hui Chen","orcid":"https://orcid.org/0009-0009-5028-9424","observed_orcids":["https://orcid.org/0009-0009-5028-9424"]},"institutions":[{"id":"https://openalex.org/I4210139608","display_name":"The First People's Hospital of Tianmen","ror":"https://ror.org/0305gdg87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Chen","raw_affiliation_strings":["Department of Oncology, Tianmen First People's Hospital, Tianmen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Tianmen First People's Hospital, Tianmen, China","institution_ids":["https://openalex.org/I4210139608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100318325","display_name":"W\u011bi Li","orcid":"https://orcid.org/0000-0002-9522-4474","observed_orcids":["https://orcid.org/0000-0002-9522-4474","https://orcid.org/0000-0003-4136-3409","https://orcid.org/0009-0009-9141-6389"]},"institutions":[{"id":"https://openalex.org/I4210139608","display_name":"The First People's Hospital of Tianmen","ror":"https://ror.org/0305gdg87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Li","raw_affiliation_strings":["Department of Oncology, Tianmen First People's Hospital, Tianmen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Tianmen First People's Hospital, Tianmen, China","institution_ids":["https://openalex.org/I4210139608"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chao Wan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139608","display_name":"The First People's Hospital of Tianmen","ror":"https://ror.org/0305gdg87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Wan","raw_affiliation_strings":["Department of Oncology, Tianmen First People's Hospital, Tianmen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Tianmen First People's Hospital, Tianmen, China","institution_ids":["https://openalex.org/I4210139608"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100752550","display_name":"Jue Zhang","orcid":"https://orcid.org/0000-0003-0440-1357","observed_orcids":["https://orcid.org/0000-0003-0440-1357"]},"institutions":[{"id":"https://openalex.org/I4210139608","display_name":"The First People's Hospital of Tianmen","ror":"https://ror.org/0305gdg87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139608"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jue Zhang","raw_affiliation_strings":["Department of CT/MRI, Tianmen First People's Hospital, Tianmen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of CT/MRI, Tianmen First People's Hospital, Tianmen, China","institution_ids":["https://openalex.org/I4210139608"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100752550"],"corresponding_institution_ids":["https://openalex.org/I4210139608"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":2.3707,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.8893462,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"12","issue":null,"first_page":"942943","last_page":"942943"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9940000176429749},{"id":"https://openalex.org/keywords/molecular-subtypes","display_name":"molecular subtypes","score":0.8399999737739563},{"id":"https://openalex.org/keywords/dynamic-contrast-enhanced-mri","display_name":"dynamic contrast-enhanced MRI","score":0.8859999775886536},{"id":"https://openalex.org/keywords/diffusion-weighted-imaging","display_name":"diffusion-weighted imaging","score":0.9470000267028809},{"id":"https://openalex.org/keywords/apparent-diffusion-coefficient","display_name":"apparent diffusion coefficient","score":1.0},{"id":"https://openalex.org/keywords/triple-negative-breast-cancer","display_name":"triple-negative breast cancer","score":0.9440000057220459},{"id":"https://openalex.org/keywords/luminal-a-subtype","display_name":"luminal A","score":0.7990000247955322},{"id":"https://openalex.org/keywords/luminal-b","display_name":"luminal B","score":0.996999979019165},{"id":"https://openalex.org/keywords/her2-positive-breast-cancer","display_name":"HER2-positive breast cancer","score":0.9879999756813049},{"id":"https://openalex.org/keywords/axillary-lymph-node-metastasis","display_name":"axillary lymph node metastasis","score":0.9549999833106995},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.925000011920929},{"id":"https://openalex.org/keywords/ki-67-proliferation-index","display_name":"Ki-67 proliferation index","score":0.8320000171661377},{"id":"https://openalex.org/keywords/rim-enhancement","display_name":"rim enhancement","score":0.6489999890327454}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8473514914512634},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.7783846855163574},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7025159001350403},{"id":"https://openalex.org/C70816921","wikidata":"https://www.wikidata.org/wiki/Q258852","display_name":"Effective diffusion coefficient","level":3,"score":0.6432538032531738},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5797101855278015},{"id":"https://openalex.org/C2777111374","wikidata":"https://www.wikidata.org/wiki/Q4959770","display_name":"Breast MRI","level":5,"score":0.5547583103179932},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.5072152614593506},{"id":"https://openalex.org/C2994142346","wikidata":"https://www.wikidata.org/wiki/Q353268","display_name":"Dynamic contrast","level":3,"score":0.4795403480529785},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.44274425506591797},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.4316861927509308},{"id":"https://openalex.org/C12868164","wikidata":"https://www.wikidata.org/wiki/Q1424533","display_name":"Mann\u2013Whitney U test","level":2,"score":0.43090540170669556},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.42652150988578796},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.42218542098999023},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42208072543144226},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.317391574382782},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.21054953336715698},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1897091269493103}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fonc.2022.942943","doi":"https://doi.org/10.3389/fonc.2022.942943","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2022.942943","pdf_url":"https://www.frontiersin.org/articles/10.3389/fonc.2022.942943/pdf","source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9389013","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9389013","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Oncol","raw_type":"Text"},{"id":"pmid:35992872","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35992872","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in oncology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:24b7d424bd4b4c7bbb8d69ab141e959e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/24b7d424bd4b4c7bbb8d69ab141e959e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Oncology, Vol 12 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fonc.2022.942943","doi":"https://doi.org/10.3389/fonc.2022.942943","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2022.942943","pdf_url":"https://www.frontiersin.org/articles/10.3389/fonc.2022.942943/pdf","source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4289942232.pdf","grobid_xml":"https://content.openalex.org/works/W4289942232.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1485355690","https://openalex.org/W1525925743","https://openalex.org/W1973196295","https://openalex.org/W1984048017","https://openalex.org/W1999494609","https://openalex.org/W2004656609","https://openalex.org/W2013797830","https://openalex.org/W2068184624","https://openalex.org/W2085659687","https://openalex.org/W2087588003","https://openalex.org/W2090595175","https://openalex.org/W2096785769","https://openalex.org/W2101979288","https://openalex.org/W2115128134","https://openalex.org/W2117775530","https://openalex.org/W2124943574","https://openalex.org/W2137028359","https://openalex.org/W2137873181","https://openalex.org/W2143204308","https://openalex.org/W2163522009","https://openalex.org/W2167067235","https://openalex.org/W2439344486","https://openalex.org/W2519820252","https://openalex.org/W2569840364","https://openalex.org/W2584754645","https://openalex.org/W2766185987","https://openalex.org/W2888818397","https://openalex.org/W2892858699","https://openalex.org/W2899882436","https://openalex.org/W2919850878","https://openalex.org/W2951683193","https://openalex.org/W2960202561","https://openalex.org/W2989809764","https://openalex.org/W3012095830","https://openalex.org/W3190971174","https://openalex.org/W3195097709","https://openalex.org/W4210371560"],"related_works":["https://openalex.org/W3032657973","https://openalex.org/W4400102766","https://openalex.org/W4409475929","https://openalex.org/W7212267214","https://openalex.org/W4404278794","https://openalex.org/W2767429470","https://openalex.org/W2988621642","https://openalex.org/W3190971174","https://openalex.org/W4415356247","https://openalex.org/W4317568099"],"abstract_inverted_index":{"Objective":[0],"To":[1],"determine":[2],"the":[3,55,99,105,112,135,162,221,232,258,299],"preoperative":[4,45],"magnetic":[5,16,22],"resonance":[6,17,23],"imaging":[7,18,24,295],"(MRI)":[8],"findings":[9,92],"of":[10,74,81,138,225,257,289,302,309],"breast":[11,40,127,139,155,303],"cancer":[12,41,128,156],"on":[13,38,60,65,312],"dynamic":[14],"contrast-enhanced":[15],"(DCE-MRI)":[19],"and":[20,31,47,57,62,78,90,101,116,122,153,187,214,246,264,274],"diffusion-weighted":[21],"(DWI)":[25],"in":[26,168],"different":[27,261],"molecular":[28,94,300,320],"subtypes.":[29,321],"Materials":[30],"methods":[32],"A":[33,142,237],"retrospective":[34],"study":[35],"was":[36,96,108,231],"conducted":[37],"116":[39],"subjects":[42],"who":[43],"underwent":[44],"MRI":[46,79,91,290],"surgery":[48,131],"or":[49,132],"biopsy.":[50],"Three":[51],"radiologists":[52],"retrospectively":[53],"assessed":[54],"morphological":[56],"kinetic":[58],"characteristics":[59],"DCE-MRI":[61],"tumor":[63,174],"detectability":[64],"DWI,":[66,220],"by":[67,130],"using":[68,98],"apparent":[69],"diffusion":[70],"coefficient":[71],"(ADC)":[72],"values":[73,311],"lesions.":[75],"The":[76,86,286],"clinicopathologic":[77],"features":[80,288],"four":[82],"subtypes":[83,95,137,301],"were":[84,166],"compared.":[85],"correlation":[87,259],"between":[88,114,260],"clinical":[89],"with":[93,126],"evaluated":[97],"chi-square":[100],"ANOVA":[102],"tests,":[103],"while":[104],"Mann\u2013Whitney":[106],"test":[107],"used":[109,293],"to":[110,235,297],"analyze":[111],"relationship":[113],"ADC":[115,223,265,275,310],"prognostic":[117,262],"factors.":[118],"Results":[119],"One":[120],"hundred":[121],"sixteen":[123],"women":[124],"diagnosed":[125],"confirmed":[129],"biopsy":[133],"had":[134,277],"following":[136],"cancer:":[140],"luminal":[141,145,236,240],"(27,":[143],"23.3%),":[144],"B":[146,241],"(56,":[147],"48.2%),":[148],"HER2":[149,247],"positive":[150,248],"(14,":[151],"12.1%),":[152],"triple-negative":[154],"(TNBC)":[157],"(19,":[158],"16.4%),":[159],"respectively.":[160],"Among":[161],"subtypes,":[163],"significant":[164,280],"differences":[165],"found":[167],"axillary":[169,270],"node":[170,272],"metastasis,":[171],"histological":[172],"grade,":[173],"shape,":[175],"rim":[176],"enhancement,":[177],"margin,":[178],"lesion":[179],"type,":[180],"intratumoral":[181],"T2":[182],"signal":[183],"intensity,":[184],"Ki-67":[185],"index,":[186],"paratumoral":[188],"enhancement":[189],"(p":[190,253,282],"<":[191,194,197,200,203,206,209,212,254],"0.001,":[192,195,198,201,204,207,210,213],"p":[193,196,199,202,205,208,211,215],"=":[216,283],"0.02,":[217],"respectively).":[218],"On":[219],"mean":[222],"value":[224,266,276],"TNBC":[226],"(0.910":[227],"\u00d7":[228,243,250],"10\u22123":[229,244,251],"mm2/s)":[230,252],"lowest":[233],"compared":[234],"(1.477\u00d710\u22123":[238],"mm2/s),":[239,245],"(0.955":[242],"(0.996":[249],"0.001).":[255],"Analysis":[256],"factors":[263],"showed":[267],"that":[268],"only":[269],"lymph":[271],"status":[273],"a":[278],"statistically":[279],"difference":[281],"0.009).":[284],"Conclusion":[285],"morphologic":[287],"can":[291],"be":[292],"as":[294],"biomarkers":[296],"identify":[298],"cancer.":[304],"In":[305],"addition,":[306],"quantitative":[307],"assessments":[308],"DWI":[313],"may":[314],"also":[315],"provide":[316],"biological":[317],"clues":[318],"about":[319]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":9}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-08-06T00:00:00"}