{"id":"https://openalex.org/W4289536038","doi":"https://doi.org/10.1590/0074-02760220031","title":"Detection of non-tuberculosus mycobacteria (NTMs) in lung samples using 16S rRNA","display_name":"Detection of non-tuberculosus mycobacteria (NTMs) in lung samples using 16S rRNA","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4289536038","doi":"https://doi.org/10.1590/0074-02760220031","pmid":"https://pubmed.ncbi.nlm.nih.gov/35920498","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9337835"},"language":"en","primary_location":{"id":"doi:10.1590/0074-02760220031","doi":"https://doi.org/10.1590/0074-02760220031","is_oa":true,"landing_page_url":"https://doi.org/10.1590/0074-02760220031","pdf_url":null,"source":{"id":"https://openalex.org/S165991124","display_name":"Mem\u00f3rias do Instituto Oswaldo Cruz","issn_l":"0074-0276","issn":["0074-0276","1678-8060"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","medline","norway-1","poland-70","russia-white-list-1","scielo"],"host_organization":"https://openalex.org/P4310312016","host_organization_name":"Instituto Oswaldo Cruz, Minist\u00e9rio da Sa\u00fade","host_organization_lineage":["https://openalex.org/P4310312016"],"host_organization_lineage_names":["Instituto Oswaldo Cruz, Minist\u00e9rio da Sa\u00fade"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mem\u00f3rias do Instituto Oswaldo Cruz","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1590/0074-02760220031","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078402424","display_name":"Franciele Costa Leite Morais","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51882195","display_name":"Universidade Luterana do Brasil","ror":"https://ror.org/00kde4z41","country_code":"BR","type":"education","lineage":["https://openalex.org/I51882195"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Franciele Costa Leite Morais","raw_affiliation_strings":["Universidade Luterana do Brasil,  Brazil","Universidade Luterana do Brasil, Programa de Pos-Graduacao em Biologia Celular e Molecular Aplicada a Saude, Canoas, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Luterana do Brasil,  Brazil","institution_ids":["https://openalex.org/I51882195"]},{"raw_affiliation_string":"Universidade Luterana do Brasil, Programa de Pos-Graduacao em Biologia Celular e Molecular Aplicada a Saude, Canoas, RS, Brasil","institution_ids":["https://openalex.org/I51882195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066478036","display_name":"Graziele Lima Bello","orcid":"https://orcid.org/0000-0001-8537-8413","observed_orcids":["https://orcid.org/0000-0001-8537-8413"]},"institutions":[{"id":"https://openalex.org/I4210127675","display_name":"Institutos Nacionais de Ci\u00eancia e Tecnologia","ror":"https://ror.org/045ydbe97","country_code":"BR","type":"government","lineage":["https://openalex.org/I11385950","https://openalex.org/I4210127675","https://openalex.org/I4210151455"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Graziele Lima Bello","raw_affiliation_strings":["Instituto Nacional de Ci\u00eancia e Tecnologia em Tuberculose,  Brasil","Instituto Nacional de Ciencia e Tecnologia em Tuberculose, Programa Institutos Nacionais de Ciencia e Tecnologia, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto Nacional de Ci\u00eancia e Tecnologia em Tuberculose,  Brasil","institution_ids":[]},{"raw_affiliation_string":"Instituto Nacional de Ciencia e Tecnologia em Tuberculose, Programa Institutos Nacionais de Ciencia e Tecnologia, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I4210127675"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074008345","display_name":"C\u00edntia Costi","orcid":"https://orcid.org/0000-0003-1531-0012","observed_orcids":["https://orcid.org/0000-0003-1531-0012"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"C\u00edntia Costi","raw_affiliation_strings":["Secretaria da Sa\u00fade do Rio Grande do Sul,  Brasil; Universidade Federal do Rio Grande do Sul,  Brazil","Secretaria da Saude do Rio Grande do Sul, Centro de Desenvolvimento Cientifico e Tecnologico, Porto Alegre, RS, BrasilUniversidade Federal do Rio Grande do Sul, Programa de Pos-Graduacao em Biologia Celular e Molecular, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Secretaria da Sa\u00fade do Rio Grande do Sul,  Brasil; Universidade Federal do Rio Grande do Sul,  Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Secretaria da Saude do Rio Grande do Sul, Centro de Desenvolvimento Cientifico e Tecnologico, Porto Alegre, RS, BrasilUniversidade Federal do Rio Grande do Sul, Programa de Pos-Graduacao em Biologia Celular e Molecular, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087239509","display_name":"Karen Barros Schmid","orcid":"https://orcid.org/0000-0002-6883-9537","observed_orcids":["https://orcid.org/0000-0002-6883-9537"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Karen Barros Schmid","raw_affiliation_strings":["Secretaria da Sa\u00fade do Rio Grande do Sul,  Brasil; Universidade Federal do Rio Grande do Sul,  Brazil","Secretaria da Saude do Rio Grande do Sul, Centro de Desenvolvimento Cientifico e Tecnologico, Porto Alegre, RS, BrasilUniversidade Federal do Rio Grande do Sul, Programa de Pos-Graduacao em Biologia Celular e Molecular, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Secretaria da Sa\u00fade do Rio Grande do Sul,  Brasil; Universidade Federal do Rio Grande do Sul,  Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Secretaria da Saude do Rio Grande do Sul, Centro de Desenvolvimento Cientifico e Tecnologico, Porto Alegre, RS, BrasilUniversidade Federal do Rio Grande do Sul, Programa de Pos-Graduacao em Biologia Celular e Molecular, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046004181","display_name":"Tain\u00e1 dos Santos Soares","orcid":"https://orcid.org/0000-0001-6492-7815","observed_orcids":["https://orcid.org/0000-0001-6492-7815"]},"institutions":[{"id":"https://openalex.org/I51882195","display_name":"Universidade Luterana do Brasil","ror":"https://ror.org/00kde4z41","country_code":"BR","type":"education","lineage":["https://openalex.org/I51882195"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Tain\u00e1 dos Santos Soares","raw_affiliation_strings":["Universidade Luterana do Brasil,  Brazil; Secretaria da Sa\u00fade do Rio Grande do Sul,  Brasil","Universidade Luterana do Brasil, Programa de Pos-Graduacao em Biologia Celular e Molecular Aplicada a Saude, Canoas, RS, BrasilSecretaria da Saude do Rio Grande do Sul, Centro de Desenvolvimento Cientifico e Tecnologico, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Luterana do Brasil,  Brazil; Secretaria da Sa\u00fade do Rio Grande do Sul,  Brasil","institution_ids":["https://openalex.org/I51882195"]},{"raw_affiliation_string":"Universidade Luterana do Brasil, Programa de Pos-Graduacao em Biologia Celular e Molecular Aplicada a Saude, Canoas, RS, BrasilSecretaria da Saude do Rio Grande do Sul, Centro de Desenvolvimento Cientifico e Tecnologico, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I51882195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075633850","display_name":"Regina Bones Barcellos","orcid":"https://orcid.org/0000-0003-0901-2422","observed_orcids":["https://orcid.org/0000-0003-0901-2422"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Regina Bones Barcellos","raw_affiliation_strings":["Secretaria da Sa\u00fade do Rio Grande do Sul,  Brasil; Universidade Federal do Rio de Janeiro,  Brazil","Secretaria da Saude do Rio Grande do Sul, Centro de Desenvolvimento Cientifico e Tecnologico, Porto Alegre, RS, BrasilUniversidade Federal do Rio de Janeiro, Programa de Pos-Graduacao em Clinica Medica, Rio de Janeiro, RJ, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Secretaria da Sa\u00fade do Rio Grande do Sul,  Brasil; Universidade Federal do Rio de Janeiro,  Brazil","institution_ids":["https://openalex.org/I122140584"]},{"raw_affiliation_string":"Secretaria da Saude do Rio Grande do Sul, Centro de Desenvolvimento Cientifico e Tecnologico, Porto Alegre, RS, BrasilUniversidade Federal do Rio de Janeiro, Programa de Pos-Graduacao em Clinica Medica, Rio de Janeiro, RJ, Brasil","institution_ids":["https://openalex.org/I122140584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013071656","display_name":"Gisela Unis","orcid":"https://orcid.org/0000-0001-8440-8561","observed_orcids":["https://orcid.org/0000-0001-8440-8561"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gisela Unis","raw_affiliation_strings":["Secretaria da Sa\u00fade do Rio Grande do Sul,  Brazil","Secretaria da Saude do Rio Grande do Sul, Hospital Sanatorio Partenon, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Secretaria da Sa\u00fade do Rio Grande do Sul,  Brazil","institution_ids":[]},{"raw_affiliation_string":"Secretaria da Saude do Rio Grande do Sul, Hospital Sanatorio Partenon, Porto Alegre, RS, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035451444","display_name":"Cl\u00e1udia Fontoura Dias","orcid":"https://orcid.org/0000-0003-1552-5275","observed_orcids":["https://orcid.org/0000-0003-1552-5275"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claudia Fontoura Dias","raw_affiliation_strings":["Secretaria da Sa\u00fade do Rio Grande do Sul,  Brazil","Secretaria da Saude do Rio Grande do Sul, Hospital Sanatorio Partenon, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Secretaria da Sa\u00fade do Rio Grande do Sul,  Brazil","institution_ids":[]},{"raw_affiliation_string":"Secretaria da Saude do Rio Grande do Sul, Hospital Sanatorio Partenon, Porto Alegre, RS, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010862962","display_name":"Pedro Eduardo Almeida da Silva","orcid":"https://orcid.org/0000-0003-1666-1295","observed_orcids":["https://orcid.org/0000-0003-1666-1295"]},"institutions":[{"id":"https://openalex.org/I126460647","display_name":"Universidade Federal do Rio Grande","ror":"https://ror.org/05hpfkn88","country_code":"BR","type":"education","lineage":["https://openalex.org/I126460647"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Pedro Eduardo Almeida da Silva","raw_affiliation_strings":["Universidade Federal do Rio Grande,  Brazil","Universidade Federal do Rio Grande, Faculdade de Medicina, Centro de Pesquisas em Microbiologia Medica, Rio Grande, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio Grande,  Brazil","institution_ids":["https://openalex.org/I126460647"]},{"raw_affiliation_string":"Universidade Federal do Rio Grande, Faculdade de Medicina, Centro de Pesquisas em Microbiologia Medica, Rio Grande, RS, Brasil","institution_ids":["https://openalex.org/I126460647"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040234186","display_name":"Maria L\u00facia Rosa Rossetti","orcid":"https://orcid.org/0000-0002-9672-9394","observed_orcids":["https://orcid.org/0000-0002-9672-9394"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I51882195","display_name":"Universidade Luterana do Brasil","ror":"https://ror.org/00kde4z41","country_code":"BR","type":"education","lineage":["https://openalex.org/I51882195"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Maria Lucia Rossetti","raw_affiliation_strings":["Universidade Luterana do Brasil,  Brazil; Instituto Nacional de Ci\u00eancia e Tecnologia em Tuberculose,  Brasil; Universidade Federal do Rio Grande do Sul,  Brazil","Universidade Luterana do Brasil, Programa de Pos-Graduacao em Biologia Celular e Molecular Aplicada a Saude, Canoas, RS, BrasilInstituto Nacional de Ciencia e Tecnologia em Tuberculose, Programa Institutos Nacionais de Ciencia e Tecnologia, Porto Alegre, RS, BrasilUniversidade Federal do Rio Grande do Sul, Programa de Pos-Graduacao em Biologia Celular e Molecular, Porto Alegre, RS, Brasil"],"raw_orcid":"https://orcid.org/0000-0002-9672-9394","affiliations":[{"raw_affiliation_string":"Universidade Luterana do Brasil,  Brazil; Instituto Nacional de Ci\u00eancia e Tecnologia em Tuberculose,  Brasil; Universidade Federal do Rio Grande do Sul,  Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I51882195"]},{"raw_affiliation_string":"Universidade Luterana do Brasil, Programa de Pos-Graduacao em Biologia Celular e Molecular Aplicada a Saude, Canoas, RS, BrasilInstituto Nacional de Ciencia e Tecnologia em Tuberculose, Programa Institutos Nacionais de Ciencia e Tecnologia, Porto Alegre, RS, BrasilUniversidade Federal do Rio Grande do Sul, Programa de Pos-Graduacao em Biologia Celular e Molecular, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I51882195"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5040234186"],"corresponding_institution_ids":["https://openalex.org/I130442723","https://openalex.org/I51882195"],"apc_list":null,"apc_paid":null,"fwci":1.718,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.82184241,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"117","issue":null,"first_page":"e220031","last_page":"e220031"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12317","display_name":"Actinomycetales infections and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nontuberculous-mycobacteria","display_name":"nontuberculous mycobacteria","score":0.996999979019165},{"id":"https://openalex.org/keywords/pulmonary-ntm-disease","display_name":"pulmonary NTM infection","score":0.7260000109672546},{"id":"https://openalex.org/keywords/sputum","display_name":"sputum","score":0.6729999780654907},{"id":"https://openalex.org/keywords/tuberculosis-differential-diagnosis","display_name":"differential diagnosis from tuberculosis","score":0.7820000052452087},{"id":"https://openalex.org/keywords/mycobacterium-gordonae","display_name":"Mycobacterium gordonae","score":0.921999990940094},{"id":"https://openalex.org/keywords/mycobacterium-abscessus","display_name":"Mycobacterium abscessus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/mycobacterium-fortuitum","display_name":"Mycobacterium fortuitum","score":0.9369999766349792},{"id":"https://openalex.org/keywords/mycobacterium-avium","display_name":"Mycobacterium avium","score":0.9670000076293945},{"id":"https://openalex.org/keywords/species-identification","display_name":"species identification","score":0.7310000061988831},{"id":"https://openalex.org/keywords/hsp65","display_name":"hsp65","score":0.824999988079071},{"id":"https://openalex.org/keywords/rpob-gene","display_name":"rpoB","score":0.902999997138977}],"concepts":[{"id":"https://openalex.org/C42062724","wikidata":"https://www.wikidata.org/wiki/Q1209205","display_name":"16S ribosomal RNA","level":3,"score":0.6814096570014954},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.508915901184082},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4427543878555298},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.42196395993232727},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3590478301048279},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24836379289627075},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.20420441031455994},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1422673761844635},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.05167165398597717}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009165","descriptor_name":"Mycobacterium Infections, Nontuberculous","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009165","descriptor_name":"Mycobacterium Infections, Nontuberculous","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009170","descriptor_name":"Nontuberculous Mycobacteria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014376","descriptor_name":"Tuberculosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060888","descriptor_name":"Real-Time Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1590/0074-02760220031","doi":"https://doi.org/10.1590/0074-02760220031","is_oa":true,"landing_page_url":"https://doi.org/10.1590/0074-02760220031","pdf_url":null,"source":{"id":"https://openalex.org/S165991124","display_name":"Mem\u00f3rias do Instituto Oswaldo Cruz","issn_l":"0074-0276","issn":["0074-0276","1678-8060"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","medline","norway-1","poland-70","russia-white-list-1","scielo"],"host_organization":"https://openalex.org/P4310312016","host_organization_name":"Instituto Oswaldo Cruz, Minist\u00e9rio da Sa\u00fade","host_organization_lineage":["https://openalex.org/P4310312016"],"host_organization_lineage_names":["Instituto Oswaldo Cruz, Minist\u00e9rio da Sa\u00fade"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mem\u00f3rias do Instituto Oswaldo Cruz","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9337835","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9337835/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9337835/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mem Inst Oswaldo Cruz","raw_type":"Text"},{"id":"pmid:35920498","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35920498","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Memorias do Instituto Oswaldo Cruz","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1590/0074-02760220031","doi":"https://doi.org/10.1590/0074-02760220031","is_oa":true,"landing_page_url":"https://doi.org/10.1590/0074-02760220031","pdf_url":null,"source":{"id":"https://openalex.org/S165991124","display_name":"Mem\u00f3rias do Instituto Oswaldo Cruz","issn_l":"0074-0276","issn":["0074-0276","1678-8060"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","medline","norway-1","poland-70","russia-white-list-1","scielo"],"host_organization":"https://openalex.org/P4310312016","host_organization_name":"Instituto Oswaldo Cruz, Minist\u00e9rio da Sa\u00fade","host_organization_lineage":["https://openalex.org/P4310312016"],"host_organization_lineage_names":["Instituto Oswaldo Cruz, Minist\u00e9rio da Sa\u00fade"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mem\u00f3rias do Instituto Oswaldo Cruz","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4289536038.pdf","grobid_xml":"https://content.openalex.org/works/W4289536038.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1807980492","https://openalex.org/W1821277652","https://openalex.org/W1963574089","https://openalex.org/W1986841871","https://openalex.org/W1987192005","https://openalex.org/W2048386972","https://openalex.org/W2078765838","https://openalex.org/W2097076431","https://openalex.org/W2099674057","https://openalex.org/W2116880660","https://openalex.org/W2124672239","https://openalex.org/W2144732401","https://openalex.org/W2148211738","https://openalex.org/W2151150929","https://openalex.org/W2164777277","https://openalex.org/W2273720181","https://openalex.org/W2280010012","https://openalex.org/W2557635410","https://openalex.org/W2607925770","https://openalex.org/W2738653904","https://openalex.org/W2789690252","https://openalex.org/W2794623846","https://openalex.org/W2804152924","https://openalex.org/W2896316627","https://openalex.org/W2908855236","https://openalex.org/W2981974192","https://openalex.org/W2994376233","https://openalex.org/W3015446788","https://openalex.org/W3038927358","https://openalex.org/W3085130662","https://openalex.org/W3097706271"],"related_works":["https://openalex.org/W3082345976","https://openalex.org/W2780132838","https://openalex.org/W2032014221","https://openalex.org/W2165201835","https://openalex.org/W2913886730","https://openalex.org/W2150554315","https://openalex.org/W2057909302","https://openalex.org/W3120351229","https://openalex.org/W3197168531","https://openalex.org/W1967060209"],"abstract_inverted_index":{"BACKGROUND:":[0],"Non-tuberculous":[1],"mycobacteria":[2],"(NTMs)":[3],"cause":[4,13],"diseases":[5],"known":[6],"as":[7],"mycobacteriosis":[8],"and":[9,16,35,42,70,92,115,165,186,208,210],"are":[10],"an":[11,40,124],"important":[12],"of":[14,20,39,63,79,84,129,140,215],"morbidity":[15],"mortality.":[17],"The":[18,146,171],"diagnosis":[19,205],"pulmonary":[21],"disease":[22,207],"caused":[23],"by":[24,28,36,155],"NTM":[25,141],"is":[26,194],"hampered":[27],"its":[29],"clinical":[30],"similarity":[31],"with":[32,89,94,123,131],"tuberculosis":[33],"(TB)":[34],"the":[37,77,132,138,181,198,203,213,216],"lack":[38],"accurate":[41],"rapid":[43],"laboratory":[44],"diagnosis.":[45],"OBJECTIVES:":[46],"Detect":[47],"DNA":[48,67],"from":[49,52,96,189],"NTMs":[50,91,114,176,185],"directly":[51],"lung":[53],"samples":[54,87],"using":[55],"real-time":[56],"polymerase":[57],"chain":[58],"reaction":[59],"(qPCR)":[60],"for":[61,113,174],"amplification":[62],"16S":[64,178],"rRNA.":[65],"Additionally,":[66],"sequencing":[68],"(hsp65":[69],"rpoB":[71],"genes)":[72],"was":[73,150],"used":[74],"to":[75,183,196,200,211],"identify":[76,197],"species":[78,149,199],"MNTs.":[80],"METHODS:":[81],"A":[82],"total":[83],"68":[85],"sputum":[86],"(54":[88],"suspected":[90],"14":[93],"TB)":[95],"patients":[97,118],"treated":[98],"at":[99],"a":[100],"referral":[101],"hospital":[102],"were":[103,110,120],"used.":[104],"FINDINGS:":[105],"Of":[106],"these,":[107],"27/54":[108],"(50%)":[109],"qPCR":[111,121,172],"positive":[112,144],"14/14":[116],"TB":[117],"(controls)":[119],"negative":[122],"almost":[125],"perfect":[126],"concordance":[127],"(Kappa":[128],"0.93)":[130],"Mycobacterium":[133,151,156,159,162,166,190],"spp.":[134],"culture.":[135],"Sequencing":[136],"confirmed":[137],"presence":[139],"in":[142,202],"all":[143],"samples.":[145],"most":[147],"common":[148],"gordonae":[152],"(33%),":[153],"followed":[154],"abscessus":[157],"(26%),":[158],"fortuitum":[160],"(22%),":[161],"avium":[163],"(15%)":[164],"peregrinum":[167],"(4%).":[168],"MAIN":[169],"CONCLUSIONS:":[170],"technique":[173],"detecting":[175],"targeting":[177],"rRNA":[179],"has":[180],"potential":[182],"detect":[184],"rapidly":[187],"differentiate":[188],"tuberculosis.":[191],"However,":[192],"it":[193],"necessary":[195],"help":[201],"differential":[204],"between":[206],"contamination,":[209],"guide":[212],"choice":[214],"therapeutic":[217],"scheme.":[218]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2022-08-03T00:00:00"}