{"id":"https://openalex.org/W4289524342","doi":"https://doi.org/10.3389/fimmu.2022.940935","title":"Critical roles of sepsis-reshaped fecal virota in attenuating sepsis severity","display_name":"Critical roles of sepsis-reshaped fecal virota in attenuating sepsis severity","publication_year":2022,"publication_date":"2022-08-02","ids":{"openalex":"https://openalex.org/W4289524342","doi":"https://doi.org/10.3389/fimmu.2022.940935","pmid":"https://pubmed.ncbi.nlm.nih.gov/35983067","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9380439"},"language":"en","primary_location":{"id":"doi:10.3389/fimmu.2022.940935","doi":"https://doi.org/10.3389/fimmu.2022.940935","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2022.940935","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2022.940935/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2022.940935/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014871813","display_name":"Wiwat Chancharoenthana","orcid":"https://orcid.org/0000-0002-2965-146X","observed_orcids":["https://orcid.org/0000-0002-2965-146X"]},"institutions":[{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Wiwat Chancharoenthana","raw_affiliation_strings":["Tropical Immunology and Translational Research Unit, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand","Tropical Nephrology Research Unit, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tropical Immunology and Translational Research Unit, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158"]},{"raw_affiliation_string":"Tropical Nephrology Research Unit, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060428036","display_name":"Nattawut Sutnu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Nattawut Sutnu","raw_affiliation_strings":["Center of Excellence on Translational Research in Inflammatory and Immunology (CETRII), Department of Microbiology, Chulalongkorn University, Bangkok, Thailand","Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Excellence on Translational Research in Inflammatory and Immunology (CETRII), Department of Microbiology, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]},{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038139869","display_name":"Peerapat Visitchanakun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Peerapat Visitchanakun","raw_affiliation_strings":["Center of Excellence on Translational Research in Inflammatory and Immunology (CETRII), Department of Microbiology, Chulalongkorn University, Bangkok, Thailand","Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Excellence on Translational Research in Inflammatory and Immunology (CETRII), Department of Microbiology, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]},{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069045968","display_name":"Vorthon Sawaswong","orcid":"https://orcid.org/0000-0003-2805-6690","observed_orcids":["https://orcid.org/0000-0003-2805-6690"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Vorthon Sawaswong","raw_affiliation_strings":["Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","Research Unit of Systems Microbiology, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]},{"raw_affiliation_string":"Research Unit of Systems Microbiology, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059244103","display_name":"Suwalak Chitcharoen","orcid":"https://orcid.org/0000-0002-9110-6884","observed_orcids":["https://orcid.org/0000-0002-9110-6884"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Suwalak Chitcharoen","raw_affiliation_strings":["Research Unit of Systems Microbiology, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Unit of Systems Microbiology, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085283841","display_name":"Sunchai Payungporn","orcid":"https://orcid.org/0000-0003-2668-110X","observed_orcids":["https://orcid.org/0000-0003-2668-110X"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sunchai Payungporn","raw_affiliation_strings":["Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","Research Unit of Systems Microbiology, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]},{"raw_affiliation_string":"Research Unit of Systems Microbiology, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090560769","display_name":"Alexandra Schuetz","orcid":"https://orcid.org/0000-0003-2829-1340","observed_orcids":["https://orcid.org/0000-0003-2829-1340","https://orcid.org/0000-0003-1158-0023"]},"institutions":[{"id":"https://openalex.org/I1280259254","display_name":"Henry M. Jackson Foundation","ror":"https://ror.org/04q9tew83","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1280259254"]},{"id":"https://openalex.org/I4210112607","display_name":"Armed Forces Research Institute of Medical Science","ror":"https://ror.org/023swxh49","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I2801080794","https://openalex.org/I4210112607","https://openalex.org/I4387156032"]},{"id":"https://openalex.org/I92664306","display_name":"Walter Reed Army Institute of Research","ror":"https://ror.org/0145znz58","country_code":"US","type":"government","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I92664306"]}],"countries":["TH","US"],"is_corresponding":false,"raw_author_name":"Alexandra Schuetz","raw_affiliation_strings":["Department of Retrovirology, Armed Forces Research Institute of Medical Sciences-United States Component, Bangkok, Thailand","Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda , MD, United States","U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Retrovirology, Armed Forces Research Institute of Medical Sciences-United States Component, Bangkok, Thailand","institution_ids":["https://openalex.org/I4210112607"]},{"raw_affiliation_string":"Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda , MD, United States","institution_ids":["https://openalex.org/I1280259254"]},{"raw_affiliation_string":"U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, United States","institution_ids":["https://openalex.org/I92664306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013315693","display_name":"Marcus Josephus Schultz","orcid":"https://orcid.org/0000-0003-3969-7792","observed_orcids":["https://orcid.org/0000-0003-3969-7792","https://orcid.org/0000-0002-4821-9955"]},"institutions":[{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]},{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210126604","display_name":"Mahidol Oxford Tropical Medicine Research Unit","ror":"https://ror.org/03fs9z545","country_code":"TH","type":"facility","lineage":["https://openalex.org/I25399158","https://openalex.org/I40120149","https://openalex.org/I4210126604","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["GB","NL","TH"],"is_corresponding":false,"raw_author_name":"Marcus J. Schultz","raw_affiliation_strings":["Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Oxford University, Oxford, United Kingdom","Department of Intensive Care & Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A), Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands","Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Oxford University, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Department of Intensive Care & Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A), Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands","institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I887064364"]},{"raw_affiliation_string":"Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210126604"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016611718","display_name":"Asada Leelahavanichkul","orcid":"https://orcid.org/0000-0002-5566-6403","observed_orcids":["https://orcid.org/0000-0002-5566-6403"]},"institutions":[{"id":"https://openalex.org/I158708052","display_name":"Chulalongkorn University","ror":"https://ror.org/028wp3y58","country_code":"TH","type":"education","lineage":["https://openalex.org/I158708052"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Asada Leelahavanichkul","raw_affiliation_strings":["Center of Excellence on Translational Research in Inflammatory and Immunology (CETRII), Department of Microbiology, Chulalongkorn University, Bangkok, Thailand","Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Excellence on Translational Research in Inflammatory and Immunology (CETRII), Department of Microbiology, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]},{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand","institution_ids":["https://openalex.org/I158708052"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5014871813","https://openalex.org/A5016611718"],"corresponding_institution_ids":["https://openalex.org/I158708052","https://openalex.org/I25399158"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":1.8184,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.8739229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"13","issue":null,"first_page":"940935","last_page":"940935"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.7666000127792358,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.7666000127792358,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.19580000638961792,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.026499999687075615,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.996999979019165},{"id":"https://openalex.org/keywords/fecal-virome","display_name":"fecal virome","score":0.9070000052452087},{"id":"https://openalex.org/keywords/bacteriophages","display_name":"bacteriophages","score":0.9660000205039978},{"id":"https://openalex.org/keywords/fecal-microbiota-transplantation","display_name":"fecal microbiota transplantation","score":0.6869999766349792},{"id":"https://openalex.org/keywords/cecal-ligation-and-puncture","display_name":"cecal ligation and puncture","score":0.8870000243186951},{"id":"https://openalex.org/keywords/podoviridae","display_name":"Podoviridae","score":0.8299999833106995},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.6430000066757202},{"id":"https://openalex.org/keywords/proteobacteria","display_name":"Proteobacteria","score":0.7229999899864197},{"id":"https://openalex.org/keywords/bacteroides","display_name":"Bacteroides","score":0.9459999799728394},{"id":"https://openalex.org/keywords/ascomycota","display_name":"Ascomycota","score":0.6949999928474426},{"id":"https://openalex.org/keywords/kidney-injury","display_name":"kidney injury","score":0.6190000176429749},{"id":"https://openalex.org/keywords/liver-injury","display_name":"liver injury","score":0.8370000123977661},{"id":"https://openalex.org/keywords/endotoxemia","display_name":"endotoxemia","score":0.8569999933242798},{"id":"https://openalex.org/keywords/bacteremia","display_name":"bacteremia","score":0.9129999876022339},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6119999885559082},{"id":"https://openalex.org/keywords/sepsis-severity","display_name":"sepsis severity","score":0.6690000295639038}],"concepts":[{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.7722921371459961},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6214951276779175},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.606146514415741},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49891090393066406},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.44305652379989624},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.4225269854068756},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002432","descriptor_name":"Cecum","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008026","descriptor_name":"Ligation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.3389/fimmu.2022.940935","doi":"https://doi.org/10.3389/fimmu.2022.940935","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2022.940935","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2022.940935/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9380439","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9380439","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Immunol","raw_type":"Text"},{"id":"pmid:35983067","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35983067","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in immunology","raw_type":"Journal Article"},{"id":"pmh:oai:ora.ox.ac.uk:uuid:b2198f20-fd65-4d28-a022-fda4da35644a","doi":null,"is_oa":false,"landing_page_url":"https://ora.ox.ac.uk/objects/uuid:b2198f20-fd65-4d28-a022-fda4da35644a/files/rbr86b544g","pdf_url":null,"source":{"id":"https://openalex.org/S4306402636","display_name":"Oxford University Research Archive (ORA) (University of Oxford)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I40120149","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/I40120149"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OpenAlex","raw_type":"Journal article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire/58ccdd1d-0c86-4e8a-be67-9cdc12d5c813","doi":null,"is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/58ccdd1d-0c86-4e8a-be67-9cdc12d5c813","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chancharoenthana, W, Sutnu, N, Visitchanakun, P, Sawaswong, V, Chitcharoen, S, Payungporn, S, Schuetz, A, Schultz, M J & Leelahavanichkul, A 2022, 'Critical roles of sepsis-reshaped fecal virota in attenuating sepsis severity', Frontiers in immunology, vol. 13, 940935. https://doi.org/10.3389/fimmu.2022.940935","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:amcpub:oai:pure.amc.nl:publications/cefdf31e-5b4d-4ecf-ad90-6abae838efc6","doi":null,"is_oa":true,"landing_page_url":"https://pure.amc.nl/en/publications/critical-roles-of-sepsisreshaped-fecal-virota-in-attenuating-sepsis-severity(cefdf31e-5b4d-4ecf-ad90-6abae838efc6).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in immunology, 13:940935. Frontiers Media S.A.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:ffbe91a6a31540bf8b1f50ba29854da9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ffbe91a6a31540bf8b1f50ba29854da9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Immunology, Vol 13 (2022)","raw_type":"article"},{"id":"doi:10.60692/0qgm1-9xk05","doi":"https://doi.org/10.60692/0qgm1-9xk05","is_oa":true,"landing_page_url":"https://doi.org/10.60692/0qgm1-9xk05","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/f86pj-6xz56","doi":"https://doi.org/10.60692/f86pj-6xz56","is_oa":true,"landing_page_url":"https://doi.org/10.60692/f86pj-6xz56","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.3389/fimmu.2022.940935","doi":"https://doi.org/10.3389/fimmu.2022.940935","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2022.940935","pdf_url":"https://www.frontiersin.org/articles/10.3389/fimmu.2022.940935/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322401","display_name":"Mahidol University","ror":"https://ror.org/01znkr924"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4289524342.pdf","grobid_xml":"https://content.openalex.org/works/W4289524342.grobid-xml"},"referenced_works_count":73,"referenced_works":["https://openalex.org/W1996393316","https://openalex.org/W2006273098","https://openalex.org/W2031461397","https://openalex.org/W2070190014","https://openalex.org/W2114862636","https://openalex.org/W2123978130","https://openalex.org/W2131271579","https://openalex.org/W2163014292","https://openalex.org/W2166395958","https://openalex.org/W2167946651","https://openalex.org/W2170551349","https://openalex.org/W2174377965","https://openalex.org/W2320745029","https://openalex.org/W2340423564","https://openalex.org/W2396765784","https://openalex.org/W2429977049","https://openalex.org/W2462034472","https://openalex.org/W2471545969","https://openalex.org/W2516886587","https://openalex.org/W2531152324","https://openalex.org/W2613237870","https://openalex.org/W2615114460","https://openalex.org/W2733471197","https://openalex.org/W2740005395","https://openalex.org/W2741628575","https://openalex.org/W2766754487","https://openalex.org/W2771421273","https://openalex.org/W2815658273","https://openalex.org/W2896590549","https://openalex.org/W2909668868","https://openalex.org/W2909798293","https://openalex.org/W2921627336","https://openalex.org/W2921820611","https://openalex.org/W2921966151","https://openalex.org/W2939472135","https://openalex.org/W2943440977","https://openalex.org/W2943878465","https://openalex.org/W2944502015","https://openalex.org/W2955899118","https://openalex.org/W2966049336","https://openalex.org/W2970037024","https://openalex.org/W2974767277","https://openalex.org/W2980981802","https://openalex.org/W2987852638","https://openalex.org/W2989221369","https://openalex.org/W2989568248","https://openalex.org/W2998853022","https://openalex.org/W3001154453","https://openalex.org/W3003850388","https://openalex.org/W3005872316","https://openalex.org/W3007565704","https://openalex.org/W3014262525","https://openalex.org/W3016808787","https://openalex.org/W3023658275","https://openalex.org/W3029420556","https://openalex.org/W3040825969","https://openalex.org/W3044507917","https://openalex.org/W3047256435","https://openalex.org/W3085050545","https://openalex.org/W3086365714","https://openalex.org/W3089175998","https://openalex.org/W3093336448","https://openalex.org/W3095153381","https://openalex.org/W3118736557","https://openalex.org/W3125599890","https://openalex.org/W3133300142","https://openalex.org/W3139054321","https://openalex.org/W3154096085","https://openalex.org/W3163781369","https://openalex.org/W3169256736","https://openalex.org/W3172399337","https://openalex.org/W3203671382","https://openalex.org/W4230615787"],"related_works":["https://openalex.org/W4315648768","https://openalex.org/W3203671382","https://openalex.org/W3036838067","https://openalex.org/W3023658275","https://openalex.org/W4281968428","https://openalex.org/W4390654026","https://openalex.org/W4283833186","https://openalex.org/W4403659913","https://openalex.org/W4413358106","https://openalex.org/W2970037024"],"abstract_inverted_index":{"Because":[0],"studies":[1],"on":[2],"all":[3,80],"fecal":[4,39,50,102,132,154,166],"organisms":[5,81],"(bacteria,":[6],"fungi,":[7],"and":[8,14,29,44,73,76,84,112,118,125,161,178],"viruses)":[9],"in":[10,64,70,145,152,175,186],"sepsis":[11,17,33,41,83,96,136,147,176],"are":[12,190],"rare":[13],"bacteriophages":[15,174],"during":[16],"might":[18],"have":[19],"adapted":[20],"against":[21],"gut":[22],"bacteria":[23,156],"with":[24,57,100],"possible":[25],"pathogenicity,":[26],"cecal":[27],"ligation":[28],"puncture":[30],"(CLP;":[31],"a":[32,187],"mouse":[34],"model)":[35],"was":[36,61],"evaluated.":[37],"In":[38,127],"bacteriome,":[40],"increased":[42,53,179],"Bacteroides":[43],"Proteobacteria":[45],"but":[46,138],"decreased":[47],"Firmicutes,":[48],"while":[49],"virome":[51],"demonstrated":[52],"Podoviridae":[54],"when":[55,98],"compared":[56,99],"sham":[58,72,101,141],"feces.":[59],"There":[60],"no":[62],"difference":[63],"the":[65,77,88,129,150,170],"fungal":[66],"microbiome":[67,167],"(predominant":[68],"Ascomycota":[69],"both":[71],"CLP":[74,93,146],"mice)":[75],"abundance":[78,180],"of":[79,90,131,172],"between":[82],"control":[85],"groups.":[86],"Interestingly,":[87],"transfers":[89,130],"feces":[91,177],"from":[92,135,140],"mice":[94],"worsened":[95],"severity":[97],"transplantation,":[103],"as":[104,158,163],"evaluated":[105,164],"by":[106,165],"mortality,":[107],"renal":[108],"injury":[109],"(serum":[110],"creatinine":[111],"histology),":[113,119],"liver":[114],"damage":[115],"(liver":[116],"enzyme":[117],"spleen":[120],"apoptosis,":[121],"serum":[122],"cytokines,":[123],"endotoxemia,":[124],"bacteremia.":[126],"contrast,":[128],"viral":[133],"particles":[134],"mice,":[137,142],"not":[139],"attenuated":[143],"inflammation":[144],"possibly":[148],"through":[149],"decrease":[151],"several":[153],"pathogenic":[155],"(such":[157],"Proteobacteria,":[159],"Gammaproteobacteria,":[160],"Prevotellaceae)":[162],"analysis.":[168],"Perhaps":[169],"isolation":[171],"favorable":[173],"ex":[181],"vivo":[182],"before":[183],"oral":[184],"treatment":[185],"high":[188],"concentration":[189],"beneficial.":[191]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":14}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2022-08-03T00:00:00"}