{"id":"https://openalex.org/W4289130587","doi":"https://doi.org/10.3389/fnut.2022.935612","title":"Modulation of gut microbiota and fecal metabolites by corn silk among high-fat diet-induced hypercholesterolemia mice","display_name":"Modulation of gut microbiota and fecal metabolites by corn silk among high-fat diet-induced hypercholesterolemia mice","publication_year":2022,"publication_date":"2022-08-01","ids":{"openalex":"https://openalex.org/W4289130587","doi":"https://doi.org/10.3389/fnut.2022.935612","pmid":"https://pubmed.ncbi.nlm.nih.gov/35978956","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9376456"},"language":"en","primary_location":{"id":"doi:10.3389/fnut.2022.935612","doi":"https://doi.org/10.3389/fnut.2022.935612","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2022.935612","pdf_url":null,"source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4289130587"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3389/fnut.2022.935612","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108060514","display_name":"Lin Ding","orcid":"https://orcid.org/0009-0007-8809-7896","observed_orcids":["https://orcid.org/0009-0007-8809-7896","https://orcid.org/0000-0003-4841-0183"]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Ding","raw_affiliation_strings":["Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shan Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shan Ren","raw_affiliation_strings":["College of Basic Medical, Qiqihar Medical University, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Basic Medical, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075465576","display_name":"Yaoxin Song","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaoxin Song","raw_affiliation_strings":["Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082370844","display_name":"Chuangang Zang","orcid":"https://orcid.org/0000-0002-9366-7714","observed_orcids":["https://orcid.org/0000-0002-9366-7714"]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chuangang Zang","raw_affiliation_strings":["Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101446495","display_name":"Yuchao Liu","orcid":"https://orcid.org/0000-0002-1645-1813","observed_orcids":["https://orcid.org/0000-0002-1645-1813"]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuchao Liu","raw_affiliation_strings":["Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046549092","display_name":"Hao Guo","orcid":"https://orcid.org/0000-0003-4381-893X","observed_orcids":["https://orcid.org/0000-0003-4381-893X"]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Guo","raw_affiliation_strings":["Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009616306","display_name":"Wenqing Yang","orcid":"https://orcid.org/0000-0002-4721-6197","observed_orcids":["https://orcid.org/0000-0002-4721-6197"]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenqing Yang","raw_affiliation_strings":["Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103059101","display_name":"Hong Guan","orcid":"https://orcid.org/0000-0001-5217-3040","observed_orcids":["https://orcid.org/0000-0001-5217-3040"]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hong Guan","raw_affiliation_strings":["Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101667921","display_name":"Jicheng Liu","orcid":"https://orcid.org/0000-0002-2200-0701","observed_orcids":["https://orcid.org/0000-0002-2200-0701"]},"institutions":[{"id":"https://openalex.org/I899859998","display_name":"Qiqihar Medical University","ror":"https://ror.org/01kzgyz42","country_code":"CN","type":"education","lineage":["https://openalex.org/I899859998"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jicheng Liu","raw_affiliation_strings":["Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","Qiqihar Academy of Medical Sciences, Qiqihar, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific Research, Science and Technology Achievement Transformation Center, Qiqihar Medical University, Qiqihar, China","institution_ids":["https://openalex.org/I899859998"]},{"raw_affiliation_string":"Qiqihar Academy of Medical Sciences, Qiqihar, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101667921","https://openalex.org/A5103059101"],"corresponding_institution_ids":["https://openalex.org/I899859998"],"apc_list":{"value":2490,"currency":"USD","value_usd":2490},"apc_paid":{"value":2490,"currency":"USD","value_usd":2490},"fwci":1.9713,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.87576624,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"9","issue":null,"first_page":"935612","last_page":"935612"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13828","display_name":"Natural Products and Biological Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corn-silk","display_name":"corn silk","score":0.968999981880188},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.8740000128746033},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9039999842643738},{"id":"https://openalex.org/keywords/fecal-metabolites","display_name":"fecal metabolites","score":0.9879999756813049},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.8989999890327454},{"id":"https://openalex.org/keywords/bile-acid-metabolism","display_name":"bile acid metabolism","score":0.7670000195503235},{"id":"https://openalex.org/keywords/turicibacter","display_name":"Turicibacter","score":0.9279999732971191},{"id":"https://openalex.org/keywords/rikenella","display_name":"Rikenella","score":0.9990000128746033},{"id":"https://openalex.org/keywords/histidine-metabolism","display_name":"histidine metabolism","score":0.8100000023841858},{"id":"https://openalex.org/keywords/sphingolipid-metabolism","display_name":"sphingolipid metabolism","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cholesterol-lowering","display_name":"cholesterol lowering","score":0.5569999814033508},{"id":"https://openalex.org/keywords/chronic-inflammation","display_name":"chronic inflammation","score":0.574999988079071},{"id":"https://openalex.org/keywords/dietary-supplementation","display_name":"dietary supplementation","score":0.3400000035762787}],"concepts":[{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.7992007732391357},{"id":"https://openalex.org/C2779399885","wikidata":"https://www.wikidata.org/wiki/Q413288","display_name":"Bile acid","level":2,"score":0.6664975881576538},{"id":"https://openalex.org/C2780420665","wikidata":"https://www.wikidata.org/wiki/Q3323035","display_name":"Lithocholic acid","level":3,"score":0.6562629342079163},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.5780974626541138},{"id":"https://openalex.org/C2780749602","wikidata":"https://www.wikidata.org/wiki/Q425680","display_name":"Deoxycholic acid","level":3,"score":0.5583556890487671},{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.5400264263153076},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.47776973247528076},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4552045166492462},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.45205894112586975},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4508112668991089},{"id":"https://openalex.org/C2781089062","wikidata":"https://www.wikidata.org/wiki/Q419028","display_name":"Chenodeoxycholic acid","level":3,"score":0.4473581910133362},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4458238184452057},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3798093795776367},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37958163022994995},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fnut.2022.935612","doi":"https://doi.org/10.3389/fnut.2022.935612","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2022.935612","pdf_url":null,"source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9376456","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9376456/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9376456/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Nutr","raw_type":"Text"},{"id":"pmid:35978956","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35978956","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in nutrition","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:0a324c95ade64bb58e3ea300120c6a61","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/0a324c95ade64bb58e3ea300120c6a61","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Nutrition, Vol 9 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fnut.2022.935612","doi":"https://doi.org/10.3389/fnut.2022.935612","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2022.935612","pdf_url":null,"source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.40450000762939453,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322217","display_name":"Department of Education, Heilongjiang Province","ror":"https://ror.org/04rn1rm44"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4289130587.pdf","grobid_xml":"https://content.openalex.org/works/W4289130587.grobid-xml"},"referenced_works_count":77,"referenced_works":["https://openalex.org/W1964010911","https://openalex.org/W2011170468","https://openalex.org/W2011949386","https://openalex.org/W2018607958","https://openalex.org/W2058684777","https://openalex.org/W2062593620","https://openalex.org/W2078810890","https://openalex.org/W2095504223","https://openalex.org/W2097136349","https://openalex.org/W2104890139","https://openalex.org/W2112944592","https://openalex.org/W2114905099","https://openalex.org/W2123561714","https://openalex.org/W2140120918","https://openalex.org/W2147259528","https://openalex.org/W2164386968","https://openalex.org/W2172618180","https://openalex.org/W2199115084","https://openalex.org/W2276866362","https://openalex.org/W2322493269","https://openalex.org/W2333194472","https://openalex.org/W2396003270","https://openalex.org/W2409571319","https://openalex.org/W2464423417","https://openalex.org/W2465534016","https://openalex.org/W2494627911","https://openalex.org/W2508346184","https://openalex.org/W2518119397","https://openalex.org/W2519977681","https://openalex.org/W2549238428","https://openalex.org/W2552283579","https://openalex.org/W2559332652","https://openalex.org/W2563819218","https://openalex.org/W2590846271","https://openalex.org/W2611732960","https://openalex.org/W2618671443","https://openalex.org/W2692388559","https://openalex.org/W2760474048","https://openalex.org/W2768617092","https://openalex.org/W2784137104","https://openalex.org/W2784250532","https://openalex.org/W2784772912","https://openalex.org/W2792066403","https://openalex.org/W2809642430","https://openalex.org/W2809895599","https://openalex.org/W2887314767","https://openalex.org/W2888956230","https://openalex.org/W2891851874","https://openalex.org/W2926774250","https://openalex.org/W2939285962","https://openalex.org/W2948642429","https://openalex.org/W2969625124","https://openalex.org/W2970423471","https://openalex.org/W2975214880","https://openalex.org/W2984669963","https://openalex.org/W3000503076","https://openalex.org/W3009231580","https://openalex.org/W3015312578","https://openalex.org/W3020009704","https://openalex.org/W3024657405","https://openalex.org/W3027118763","https://openalex.org/W3040685676","https://openalex.org/W3044917564","https://openalex.org/W3047109536","https://openalex.org/W3079127461","https://openalex.org/W3086732443","https://openalex.org/W3108695310","https://openalex.org/W3115276438","https://openalex.org/W3128202560","https://openalex.org/W3133864627","https://openalex.org/W3145467143","https://openalex.org/W3161650312","https://openalex.org/W3183477945","https://openalex.org/W4200001359","https://openalex.org/W4200153486","https://openalex.org/W4200539924","https://openalex.org/W4206679594"],"related_works":["https://openalex.org/W2464423417","https://openalex.org/W7134277534","https://openalex.org/W2097116634","https://openalex.org/W4401698389","https://openalex.org/W4416109216","https://openalex.org/W7095964080","https://openalex.org/W4389143645","https://openalex.org/W4382403606","https://openalex.org/W3013579604","https://openalex.org/W3006495277"],"abstract_inverted_index":{"Corn":[0],"silk":[1],"(CS)":[2],"is":[3,87],"known":[4],"to":[5,27],"reduce":[6],"cholesterol":[7,112],"levels,":[8],"but":[9],"its":[10],"underlying":[11],"mechanisms":[12],"remain":[13],"elusive":[14],"concerning":[15],"the":[16,73,204,209,212,227],"gut":[17,31,120,213],"microbiota":[18,32,214],"and":[19,34,51,69,93,109,123,135,145,172,181,197,215],"metabolites.":[20],"The":[21,56],"aim":[22],"of":[23,76,230],"our":[24],"work":[25],"was":[26],"explore":[28],"how":[29],"altered":[30,119],"composition":[33,122],"metabolite":[35],"profile":[36],"are":[37],"influenced":[38],"by":[39,89],"CS":[40,77,90,117,158,231],"intervention":[41,92],"in":[42,96,99,211],"mice":[43,58],"using":[44],"integrated":[45],"16S":[46],"ribosomal":[47],"RNA":[48],"(rRNA)":[49],"sequencing":[50],"an":[52],"untargeted":[53],"metabolomics":[54,154],"methodology.":[55],"C57BL/6J":[57],"were":[59,147],"fed":[60],"a":[61,65,97,202,223],"normal":[62],"control":[63],"diet,":[64],"high-fat":[66],"diet":[67],"(HFD),":[68],"HFD":[70],"supplemented":[71],"with":[72,150],"aqueous":[74],"extract":[75,91,118,159],"(80":[78],"mg/mL)":[79],"for":[80,226],"8":[81],"weeks.":[82],"HFD-induced":[83],"chronic":[84],"inflammation":[85],"damage":[86],"alleviated":[88],"also":[94],"resulted":[95],"reduction":[98],"body":[100],"weight,":[101],"daily":[102],"energy":[103],"intake":[104],"as":[105,107],"well":[106],"serum":[108],"hepatic":[110],"total":[111],"(TC)":[113],"levels.":[114],"In":[115],"addition,":[116],"microbial":[121],"regulated":[124],"specific":[125],"genera":[126],"viz.":[127],"Allobaculum,":[128],"Turicibacter,":[129],"Romboutsia,":[130],"Streptococcus,":[131],"Sporobacter,":[132],"Christensenella,":[133],"ClostridiumXVIII,":[134],"Rikenella.":[136],"Using":[137],"Spearman\u2019s":[138],"correlation":[139],"analysis,":[140],"we":[141],"determined":[142],"that":[143,157,208],"Turicibacter":[144],"Rikenella":[146],"negatively":[148],"correlated":[149],"hypercholesterolemia-related":[151],"parameters.":[152],"Fecal":[153],"analysis":[155],"revealed":[156],"influences":[160],"multiple":[161],"metabolic":[162],"pathways":[163],"like":[164],"histidine":[165],"metabolism-related":[166,176],"metabolites":[167,177,186],"(urocanic":[168],"acid,":[169],"methylimidazole":[170],"acetaldehyde,":[171],"methiodimethylimidazoleacetic":[173],"acid),":[174],"sphingolipid":[175],"(sphinganine,":[178],"3-dehydrosphinganine,":[179],"sphingosine),":[180],"some":[182],"bile":[183,218],"acids":[184],"biosynthesis-related":[185],"including":[187],"chenodeoxycholic":[188],"acid":[189,192,195,199,219],"(CDCA),":[190],"lithocholic":[191],"(LCA),":[193],"ursodeoxycholic":[194],"(UDCA),":[196],"glycoursodeoxycholic":[198],"(GUDCA).":[200],"As":[201],"whole,":[203],"present":[205],"study":[206],"indicates":[207],"modifications":[210],"subsequent":[216],"host":[217],"metabolism":[220],"may":[221],"be":[222],"potential":[224],"mechanism":[225],"antihypercholesterolemic":[228],"effects":[229],"extract.":[232]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":11}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2022-08-01T00:00:00"}
