{"id":"https://openalex.org/W4288884580","doi":"https://doi.org/10.7759/cureus.27492","title":"Noradrenergic Pheochromocytoma: A Case Report","display_name":"Noradrenergic Pheochromocytoma: A Case Report","publication_year":2022,"publication_date":"2022-07-30","ids":{"openalex":"https://openalex.org/W4288884580","doi":"https://doi.org/10.7759/cureus.27492","pmid":"https://pubmed.ncbi.nlm.nih.gov/36060320","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9424061"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.27492","doi":"https://doi.org/10.7759/cureus.27492","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.27492","pdf_url":"https://www.cureus.com/articles/106614-noradrenergic-pheochromocytoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/106614-noradrenergic-pheochromocytoma-a-case-report.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059021095","display_name":"M.A. Essafi","orcid":"https://orcid.org/0009-0006-2788-7571","observed_orcids":["https://orcid.org/0009-0006-2788-7571"]},"institutions":[{"id":"https://openalex.org/I4210134492","display_name":"Centre Hospitalier Universitaire Hassan II","ror":"https://ror.org/03m2nqg26","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210134492"]}],"countries":["MA"],"is_corresponding":true,"raw_author_name":"Mohammed Amine Essafi","raw_affiliation_strings":["Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR","institution_ids":["https://openalex.org/I4210134492"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sanae Habibi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134492","display_name":"Centre Hospitalier Universitaire Hassan II","ror":"https://ror.org/03m2nqg26","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210134492"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Sanae Habibi","raw_affiliation_strings":["Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR","institution_ids":["https://openalex.org/I4210134492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085905240","display_name":"Hayat Aynaou","orcid":"https://orcid.org/0000-0001-5378-7423","observed_orcids":["https://orcid.org/0000-0001-5378-7423"]},"institutions":[{"id":"https://openalex.org/I4210134492","display_name":"Centre Hospitalier Universitaire Hassan II","ror":"https://ror.org/03m2nqg26","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210134492"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Hayat Aynaou","raw_affiliation_strings":["Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR","institution_ids":["https://openalex.org/I4210134492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107832230","display_name":"Houda Salhi","orcid":"https://orcid.org/0000-0003-0487-1738","observed_orcids":["https://orcid.org/0000-0003-0487-1738"]},"institutions":[{"id":"https://openalex.org/I4210134492","display_name":"Centre Hospitalier Universitaire Hassan II","ror":"https://ror.org/03m2nqg26","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210134492"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Houda Salhi","raw_affiliation_strings":["Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR","institution_ids":["https://openalex.org/I4210134492"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109394044","display_name":"Hanan El Ouahabi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134492","display_name":"Centre Hospitalier Universitaire Hassan II","ror":"https://ror.org/03m2nqg26","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210134492"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Hanan El Ouahabi","raw_affiliation_strings":["Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR","institution_ids":["https://openalex.org/I4210134492"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5059021095"],"corresponding_institution_ids":["https://openalex.org/I4210134492"],"apc_list":null,"apc_paid":null,"fwci":0.2081,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.41227014,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"14","issue":"7","first_page":"e27492","last_page":"e27492"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11054","display_name":"Adrenal and Paraganglionic Tumors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11054","display_name":"Adrenal and Paraganglionic Tumors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12226","display_name":"Neuroblastoma Research and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11173","display_name":"Neurofibromatosis and Schwannoma Cases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pheochromocytoma","display_name":"pheochromocytoma","score":0.972000002861023},{"id":"https://openalex.org/keywords/adrenal-tumors","display_name":"adrenal tumors","score":0.640999972820282},{"id":"https://openalex.org/keywords/retroperitoneal-mass","display_name":"retroperitoneal mass","score":0.906000018119812},{"id":"https://openalex.org/keywords/adolescents","display_name":"adolescents","score":0.41999998688697815},{"id":"https://openalex.org/keywords/catecholamine-release","display_name":"catecholamine release","score":0.6480000019073486},{"id":"https://openalex.org/keywords/adrenalectomy","display_name":"adrenalectomy","score":0.9509999752044678},{"id":"https://openalex.org/keywords/alpha-blockers","display_name":"alpha-blockers","score":0.4970000088214874},{"id":"https://openalex.org/keywords/pass-score","display_name":"PASS score","score":0.7020000219345093},{"id":"https://openalex.org/keywords/vhl","display_name":"VHL","score":0.8349999785423279},{"id":"https://openalex.org/keywords/ret","display_name":"RET","score":0.5889999866485596},{"id":"https://openalex.org/keywords/sdhb","display_name":"SDHB","score":0.6190000176429749},{"id":"https://openalex.org/keywords/sdhd","display_name":"SDHD","score":0.4779999852180481},{"id":"https://openalex.org/keywords/genetic-testing","display_name":"genetic testing","score":0.3659999966621399}],"concepts":[{"id":"https://openalex.org/C2779512018","wikidata":"https://www.wikidata.org/wiki/Q536269","display_name":"Pheochromocytoma","level":2,"score":0.954342246055603},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9230642318725586},{"id":"https://openalex.org/C2776783082","wikidata":"https://www.wikidata.org/wiki/Q412766","display_name":"Metanephrine","level":3,"score":0.882223904132843},{"id":"https://openalex.org/C2779505177","wikidata":"https://www.wikidata.org/wiki/Q517109","display_name":"Normetanephrine","level":3,"score":0.7185559868812561},{"id":"https://openalex.org/C2780087391","wikidata":"https://www.wikidata.org/wiki/Q366774","display_name":"Adrenalectomy","level":2,"score":0.5752788186073303},{"id":"https://openalex.org/C2780744430","wikidata":"https://www.wikidata.org/wiki/Q14916125","display_name":"SDHB","level":5,"score":0.5636953115463257},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.533078670501709},{"id":"https://openalex.org/C2776734335","wikidata":"https://www.wikidata.org/wiki/Q581592","display_name":"Paraganglioma","level":2,"score":0.5141454339027405},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.43796926736831665},{"id":"https://openalex.org/C2780694816","wikidata":"https://www.wikidata.org/wiki/Q712294","display_name":"Adrenal gland","level":2,"score":0.4226442575454712},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3808412551879883},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.35659170150756836},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3522070050239563},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.336506724357605},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.09022784233093262},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07186508178710938},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.27492","doi":"https://doi.org/10.7759/cureus.27492","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.27492","pdf_url":"https://www.cureus.com/articles/106614-noradrenergic-pheochromocytoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmid:36060320","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36060320","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:9424061","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9424061/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7759/cureus.27492","doi":"https://doi.org/10.7759/cureus.27492","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.27492","pdf_url":"https://www.cureus.com/articles/106614-noradrenergic-pheochromocytoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4288884580.pdf","grobid_xml":"https://content.openalex.org/works/W4288884580.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W1541841144","https://openalex.org/W1918582406","https://openalex.org/W1972618930","https://openalex.org/W2006972329","https://openalex.org/W2093658122","https://openalex.org/W2125562267","https://openalex.org/W2135003179","https://openalex.org/W3025592089"],"related_works":["https://openalex.org/W3211806257","https://openalex.org/W4403153811","https://openalex.org/W3123188101","https://openalex.org/W2943920713","https://openalex.org/W6911625843","https://openalex.org/W3128506088","https://openalex.org/W2944489743","https://openalex.org/W4415451952","https://openalex.org/W4210999210","https://openalex.org/W3211631317"],"abstract_inverted_index":{"Pheochromocytomas":[0],"and":[1,70,116,126,148],"paragangliomas":[2],"are":[3,12],"rare":[4],"neuroendocrine":[5],"tumors":[6],"developed":[7],"from":[8],"chromaffin":[9],"cells.":[10],"They":[11],"exceptional":[13],"in":[14,43,52],"children":[15],"with":[16,31,86,111],"an":[17,60,87],"atypical":[18],"symptomatology.":[19],"We":[20],"report":[21],"here":[22],"a":[23,26,32,93],"case":[24],"of":[25,46,63,95,99,113],"17-year-old":[27],"boy":[28],"who":[29],"presented":[30],"left":[33,54],"retroperitoneal":[34],"mass":[35],"discovered":[36],"on":[37],"thoracic-abdominal-pelvic":[38],"computed":[39],"tomography":[40],"(CT)":[41],"scan":[42],"the":[44,53,100,143],"presence":[45],"diffuse":[47],"abdominal":[48],"pain,":[49],"more":[50],"pronounced":[51],"hypochondrium.":[55],"The":[56,107],"exploration":[57],"had":[58,79,91],"objectified":[59],"exclusive":[61],"secretion":[62],"urinary":[64,117],"normetanephrine":[65],"over":[66],"24":[67],"hours.":[68],"Metanephrine":[69],"3":[71],"ortho":[72],"methyldopamine":[73],"were":[74],"within":[75],"normal":[76],"limits.":[77],"He":[78,129],"adrenalectomy":[80],"after":[81],"controlling":[82],"his":[83],"blood":[84,114],"pressure":[85,115],"alpha":[88],"blocker.":[89],"Histology":[90],"confirmed":[92],"pheochromocytoma":[94],"non-aggressive":[96],"potential":[97],"Pheochromocytoma":[98],"Adrenal":[101],"gland":[102],"Scaled":[103],"Score":[104],"(PASS)":[105],"2.":[106],"evolution":[108],"was":[109],"favorable":[110],"normalization":[112],"catecholamines":[118],"at":[119],"one":[120,127],"week,":[121],"three":[122],"months,":[123,125],"six":[124],"year.":[128],"tested":[130],"negative":[131],"for":[132],"hereditary":[133],"syndromic":[134],"including":[135],"Von":[136],"Hippel-Lindau":[137],"(VHL),":[138],"RET":[139],"genes,":[140],"subject":[141],"to":[142],"succinate":[144],"dehydrogenase":[145],"complex":[146],"B":[147],"D":[149],"subunit":[150],"genes":[151],"(SDHB-D),":[152],"which":[153],"have":[154],"been":[155],"requested.":[156]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-07-31T00:00:00"}