{"id":"https://openalex.org/W4288748742","doi":"https://doi.org/10.1111/ped.15315","title":"Antenatal magnesium sulfate and ritodrine increased potassium levels in preterm infants: A cohort study","display_name":"Antenatal magnesium sulfate and ritodrine increased potassium levels in preterm infants: A cohort study","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4288748742","doi":"https://doi.org/10.1111/ped.15315","pmid":"https://pubmed.ncbi.nlm.nih.gov/36331237"},"language":"en","primary_location":{"id":"doi:10.1111/ped.15315","doi":"https://doi.org/10.1111/ped.15315","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ped.15315","pdf_url":null,"source":{"id":"https://openalex.org/S113298455","display_name":"Pediatrics International","issn_l":"1328-8067","issn":["1328-8067","1442-200X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045065496","display_name":"Seigo Hira","orcid":"https://orcid.org/0000-0001-6660-5721","observed_orcids":["https://orcid.org/0000-0001-6660-5721"]},"institutions":[{"id":"https://openalex.org/I4210125884","display_name":"Saiseikai Suita Hospital","ror":"https://ror.org/03ehcbt32","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125884"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Seigo Hira","raw_affiliation_strings":["Department of Pediatrics Saiseikai Suita Hospital Suita Osaka Japan"],"raw_orcid":"https://orcid.org/0000-0001-6660-5721","affiliations":[{"raw_affiliation_string":"Department of Pediatrics Saiseikai Suita Hospital Suita Osaka Japan","institution_ids":["https://openalex.org/I4210125884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110107618","display_name":"Ryoichi Ban","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125884","display_name":"Saiseikai Suita Hospital","ror":"https://ror.org/03ehcbt32","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125884"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryoichi Ban","raw_affiliation_strings":["Department of Pediatrics Saiseikai Suita Hospital Suita Osaka Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics Saiseikai Suita Hospital Suita Osaka Japan","institution_ids":["https://openalex.org/I4210125884"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Satoru Ogawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125884","display_name":"Saiseikai Suita Hospital","ror":"https://ror.org/03ehcbt32","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125884"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoru Ogawa","raw_affiliation_strings":["Department of Pediatrics Saiseikai Suita Hospital Suita Osaka Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics Saiseikai Suita Hospital Suita Osaka Japan","institution_ids":["https://openalex.org/I4210125884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109803254","display_name":"Kyoko Sakai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125884","display_name":"Saiseikai Suita Hospital","ror":"https://ror.org/03ehcbt32","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125884"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kyoko Sakai","raw_affiliation_strings":["Department of Laboratory Medicine Saiseikai Suita Hospital Suita Osaka Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine Saiseikai Suita Hospital Suita Osaka Japan","institution_ids":["https://openalex.org/I4210125884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031997347","display_name":"Kimitaka Takitani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205143321","display_name":"Osaka Medical and Pharmaceutical University","ror":"https://ror.org/01y2kdt21","country_code":"JP","type":"education","lineage":["https://openalex.org/I205143321"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kimitaka Takitani","raw_affiliation_strings":["Department of Pediatrics Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan","institution_ids":["https://openalex.org/I205143321"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024192180","display_name":"Akira Ashida","orcid":"https://orcid.org/0000-0001-5972-946X","observed_orcids":["https://orcid.org/0000-0001-5972-946X"]},"institutions":[{"id":"https://openalex.org/I205143321","display_name":"Osaka Medical and Pharmaceutical University","ror":"https://ror.org/01y2kdt21","country_code":"JP","type":"education","lineage":["https://openalex.org/I205143321"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Ashida","raw_affiliation_strings":["Department of Pediatrics Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan","institution_ids":["https://openalex.org/I205143321"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5045065496"],"corresponding_institution_ids":["https://openalex.org/I4210125884"],"apc_list":{"value":2700,"currency":"USD","value_usd":2700},"apc_paid":null,"fwci":0.2505,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.54194384,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"64","issue":"1","first_page":"e15315","last_page":"e15315"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.25589999556541443,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.25589999556541443,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11290","display_name":"Preterm Birth and Chorioamnionitis","score":0.17630000412464142,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.10050000250339508,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antenatal-magnesium-sulfate","display_name":"antenatal magnesium sulfate","score":0.9409999847412109},{"id":"https://openalex.org/keywords/ritodrine","display_name":"ritodrine","score":0.9850000143051147},{"id":"https://openalex.org/keywords/preterm-infants","display_name":"preterm infants","score":0.9039999842643738},{"id":"https://openalex.org/keywords/serum-potassium","display_name":"serum potassium","score":0.8640000224113464},{"id":"https://openalex.org/keywords/hyperkalemia","display_name":"hyperkalemia","score":0.8859999775886536},{"id":"https://openalex.org/keywords/fractional-excretion-of-potassium","display_name":"fractional excretion of potassium","score":0.8769999742507935},{"id":"https://openalex.org/keywords/preterm-labor-prevention","display_name":"preterm labor prevention","score":0.6819999814033508}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9181650280952454},{"id":"https://openalex.org/C2776561140","wikidata":"https://www.wikidata.org/wiki/Q5577596","display_name":"Ritodrine","level":4,"score":0.8472689986228943},{"id":"https://openalex.org/C2908881489","wikidata":"https://www.wikidata.org/wiki/Q545234","display_name":"Tocolytic agent","level":5,"score":0.6091459393501282},{"id":"https://openalex.org/C543218039","wikidata":"https://www.wikidata.org/wiki/Q660","display_name":"Magnesium","level":2,"score":0.573666512966156},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.5297556519508362},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5200081467628479},{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.5058936476707458},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4887409210205078},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4583780765533447},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.4276093542575836},{"id":"https://openalex.org/C3019152611","wikidata":"https://www.wikidata.org/wiki/Q625506","display_name":"Preterm labor","level":4,"score":0.35141170024871826},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21962571144104004},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008278","descriptor_name":"Magnesium Sulfate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012312","descriptor_name":"Ritodrine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D013431","descriptor_name":"Sulfates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/ped.15315","doi":"https://doi.org/10.1111/ped.15315","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ped.15315","pdf_url":null,"source":{"id":"https://openalex.org/S113298455","display_name":"Pediatrics International","issn_l":"1328-8067","issn":["1328-8067","1442-200X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics International","raw_type":"journal-article"},{"id":"pmid:36331237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36331237","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics international : official journal of the Japan Pediatric Society","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W185998445","https://openalex.org/W1708013175","https://openalex.org/W1926268864","https://openalex.org/W1973674511","https://openalex.org/W2007161456","https://openalex.org/W2008170064","https://openalex.org/W2017887617","https://openalex.org/W2018231713","https://openalex.org/W2053831207","https://openalex.org/W2093383663","https://openalex.org/W2099747750","https://openalex.org/W2107804048","https://openalex.org/W2120392137","https://openalex.org/W2121960517","https://openalex.org/W2137962489","https://openalex.org/W2149991362","https://openalex.org/W2237603801","https://openalex.org/W2336406518","https://openalex.org/W2570375333","https://openalex.org/W2768345275","https://openalex.org/W2807000846","https://openalex.org/W3022781549"],"related_works":["https://openalex.org/W4406466857","https://openalex.org/W3022781549","https://openalex.org/W4296311998","https://openalex.org/W4212974763","https://openalex.org/W4385671573","https://openalex.org/W2105693296","https://openalex.org/W2004420941","https://openalex.org/W1983317614","https://openalex.org/W7170500129","https://openalex.org/W2008874698"],"abstract_inverted_index":{"BACKGROUND:":[0],"Ritodrine":[1],"and":[2,31,49,73,78,92,98,138,148,191,201,255],"magnesium":[3,135,146,253],"sulfate":[4,12,136,147,254],"are":[5],"administered":[6,15],"to":[7,16,24,39],"prevent":[8,17],"preterm":[9,47,246],"labor.":[10],"Magnesium":[11],"is":[13],"also":[14],"preeclampsia.":[18],"These":[19],"drugs":[20],"have":[21],"been":[22],"reported":[23],"increase":[25],"potassium":[26,44,100,155,164,228,241],"levels":[27,45,95,101,156,165,242],"in":[28,46,173,180,197,217,234,245],"pregnant":[29],"women":[30],"neonates.":[32],"The":[33,109,239],"aim":[34],"of":[35,111,122,131,141,227,229,248],"this":[36],"study":[37,56],"was":[38,57],"investigate":[40],"the":[41,85,120,129,139,160,174,181,198,205,218,235],"relationship":[42],"between":[43,70],"infants":[48,64,113,124,133,143,216,247],"antenatal":[50,86,116,126,252],"treatment.":[51],"METHODS:":[52],"This":[53],"prospective":[54],"cohort":[55],"conducted":[58],"at":[59,66,96],"Saiseikai":[60],"Suita":[61],"Hospital.":[62],"Preterm":[63],"born":[65],"<35":[67],"weeks'":[68],"gestation":[69],"October":[71],"2012":[72],"September":[74],"2014":[75],"were":[76,106,157,170],"recruited":[77],"divided":[79],"into":[80],"four":[81,161],"groups":[82,203],"based":[83],"on":[84,258],"treatment":[87,117],"their":[88],"mothers":[89,110,121,130,140,249],"received.":[90],"Serum":[91],"urine":[93],"electrolyte":[94],"birth":[97,105,169],"serum":[99],"1":[102,261],"day":[103,167,260],"after":[104,168],"measured.":[107],"RESULTS:":[108],"16":[112],"received":[114,125,134,144,251],"no":[115],"(condition":[118],"C);":[119],"29":[123],"ritodrine":[127,149,256],"(R);":[128],"seven":[132],"(M);":[137],"15":[142],"both":[145],"(M":[150],"+":[151,176,207,220],"R).":[152],"At":[153],"birth,":[154],"similar":[158],"among":[159],"groups.":[162,237],"However,":[163],"a":[166,224],"significantly":[171],"higher":[172],"M":[175,202,206,219],"R":[177,208,221],"group":[178,222],"than":[179],"other":[182,236],"groups:":[183],"median":[184],"(min.-max.)":[185],"mEq/L":[186],"4.8":[187,189],"(3.8-6.2),":[188],"(3.6-6.0),":[190],"4.4":[192],"(3.8-5.9)":[193],"vs.":[194],"5.8":[195],"(4.9-7.2),":[196],"C,":[199],"R,":[200],"versus":[204],"group,":[209],"respectively":[210],"(P":[211],"<":[212],"0.01).":[213],"Significantly":[214],"more":[215],"exhibited":[223],"fractional":[225],"excretion":[226],"<10%":[230],"compared":[231],"with":[232],"those":[233],"CONCLUSION:":[238],"increased":[240],"we":[243],"observe":[244],"who":[250],"administration":[257],"postnatal":[259],"warrant":[262],"monitoring":[263],"by":[264],"neonatologists.":[265]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-07-30T00:00:00"}