{"id":"https://openalex.org/W4288700174","doi":"https://doi.org/10.1186/s12931-022-02122-6","title":"Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system","display_name":"Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system","publication_year":2022,"publication_date":"2022-07-29","ids":{"openalex":"https://openalex.org/W4288700174","doi":"https://doi.org/10.1186/s12931-022-02122-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/35906615","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9338466"},"language":"en","primary_location":{"id":"doi:10.1186/s12931-022-02122-6","doi":"https://doi.org/10.1186/s12931-022-02122-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12931-022-02122-6","pdf_url":"https://respiratory-research.biomedcentral.com/counter/pdf/10.1186/s12931-022-02122-6","source":{"id":"https://openalex.org/S186153782","display_name":"Respiratory Research","issn_l":"1465-9921","issn":["1465-9921","1465-993X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory Research","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://respiratory-research.biomedcentral.com/counter/pdf/10.1186/s12931-022-02122-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024927969","display_name":"Huaiyu Xiong","orcid":"https://orcid.org/0000-0002-8126-6470","observed_orcids":["https://orcid.org/0000-0002-8126-6470"]},"institutions":[{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huaiyu Xiong","raw_affiliation_strings":["Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China","institution_ids":["https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jing Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Yang","raw_affiliation_strings":["Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China","institution_ids":["https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075972413","display_name":"Jun Qing Guo","orcid":"https://orcid.org/0000-0002-3621-9165","observed_orcids":["https://orcid.org/0000-0002-3621-9165"]},"institutions":[{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Guo","raw_affiliation_strings":["Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China","institution_ids":["https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066213716","display_name":"Aijia Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Aijia Ma","raw_affiliation_strings":["Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China","institution_ids":["https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100408154","display_name":"Bo Wang","orcid":"https://orcid.org/0000-0002-9196-6366","observed_orcids":["https://orcid.org/0000-0002-9196-6366"]},"institutions":[{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bo Wang","raw_affiliation_strings":["Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China. wchicu@126.com","Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China. wchicu@126.com","institution_ids":["https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China","institution_ids":["https://openalex.org/I4210089761"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074217807","display_name":"Yan Ming Kang","orcid":"https://orcid.org/0000-0002-5715-3900","observed_orcids":["https://orcid.org/0000-0002-5715-3900"]},"institutions":[{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yan Kang","raw_affiliation_strings":["Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China. kangyan@scu.edu.cn","Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China. kangyan@scu.edu.cn","institution_ids":["https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Department of Critical Care Medicine, West China Hospital of Sichuan University, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu, 610000, Sichuan, China","institution_ids":["https://openalex.org/I4210089761"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5074217807","https://openalex.org/A5100408154"],"corresponding_institution_ids":["https://openalex.org/I4210089761"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":0.5062,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.48306528,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"23","issue":"1","first_page":"196","last_page":"196"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","score":0.3499000072479248,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","score":0.3499000072479248,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.2581000030040741,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13415","display_name":"Calcium signaling and nucleotide metabolism","score":0.07169999927282333,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/piezo-channels","display_name":"Piezo channels","score":0.8450000286102295},{"id":"https://openalex.org/keywords/mechanosensitive-channels","display_name":"mechanosensitive ion channels","score":0.9860000014305115},{"id":"https://openalex.org/keywords/respiratory-system","display_name":"respiratory system","score":0.8510000109672546},{"id":"https://openalex.org/keywords/pulmonary-hypertension","display_name":"pulmonary hypertension","score":0.9330000281333923},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.9829999804496765},{"id":"https://openalex.org/keywords/apnea","display_name":"apnea","score":0.921999990940094},{"id":"https://openalex.org/keywords/lung-disease","display_name":"lung disease","score":0.7059999704360962},{"id":"https://openalex.org/keywords/mechanotransduction","display_name":"mechanotransduction","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C4001165","wikidata":"https://www.wikidata.org/wiki/Q6804689","display_name":"Mechanosensitive channels","level":4,"score":0.964788556098938},{"id":"https://openalex.org/C50254741","wikidata":"https://www.wikidata.org/wiki/Q62536","display_name":"Ion channel","level":3,"score":0.7110973596572876},{"id":"https://openalex.org/C145314362","wikidata":"https://www.wikidata.org/wiki/Q6804689","display_name":"Stretch-activated ion channel","level":5,"score":0.5901002287864685},{"id":"https://openalex.org/C2780785647","wikidata":"https://www.wikidata.org/wiki/Q18034667","display_name":"PIEZO1","level":5,"score":0.5816987752914429},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.535127580165863},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5295639634132385},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5160953402519226},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4728149175643921},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.4404633939266205},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.4372600018978119},{"id":"https://openalex.org/C25194021","wikidata":"https://www.wikidata.org/wiki/Q17157162","display_name":"Mechanosensation","level":4,"score":0.4337959587574005},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3233799338340759},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31868451833724976},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.19025152921676636},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1800728738307953},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1767798364162445},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1732674241065979},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12593188881874084}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012137","descriptor_name":"Respiratory System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D040542","descriptor_name":"Mechanotransduction, Cellular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12931-022-02122-6","doi":"https://doi.org/10.1186/s12931-022-02122-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12931-022-02122-6","pdf_url":"https://respiratory-research.biomedcentral.com/counter/pdf/10.1186/s12931-022-02122-6","source":{"id":"https://openalex.org/S186153782","display_name":"Respiratory Research","issn_l":"1465-9921","issn":["1465-9921","1465-993X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9338466","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9338466","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respir Res","raw_type":"Text"},{"id":"pmid:35906615","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35906615","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory research","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:fa15fd0cc4494ccd95f3ad6a436c7ab7","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/fa15fd0cc4494ccd95f3ad6a436c7ab7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Respiratory Research, Vol 23, Iss 1, Pp 1-9 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12931-022-02122-6","doi":"https://doi.org/10.1186/s12931-022-02122-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12931-022-02122-6","pdf_url":"https://respiratory-research.biomedcentral.com/counter/pdf/10.1186/s12931-022-02122-6","source":{"id":"https://openalex.org/S186153782","display_name":"Respiratory Research","issn_l":"1465-9921","issn":["1465-9921","1465-993X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5327689620","display_name":null,"funder_award_id":"1.3.5 project","funder_id":"https://openalex.org/F4320336042","funder_display_name":"West China Hospital, Sichuan University"},{"id":"https://openalex.org/G7279392646","display_name":null,"funder_award_id":"ZYJC18006","funder_id":"https://openalex.org/F4320322990","funder_display_name":"Sichuan University"},{"id":"https://openalex.org/G7899741169","display_name":null,"funder_award_id":"1.3.5","funder_id":"https://openalex.org/F4320336042","funder_display_name":"West China Hospital, Sichuan University"}],"funders":[{"id":"https://openalex.org/F4320322990","display_name":"Sichuan University","ror":"https://ror.org/011ashp19"},{"id":"https://openalex.org/F4320336042","display_name":"West China Hospital, Sichuan University","ror":"https://ror.org/007mrxy13"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4288700174.pdf","grobid_xml":"https://content.openalex.org/works/W4288700174.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W1750880444","https://openalex.org/W1983897833","https://openalex.org/W1991643569","https://openalex.org/W1995062036","https://openalex.org/W1999720993","https://openalex.org/W2003565037","https://openalex.org/W2014795299","https://openalex.org/W2029016740","https://openalex.org/W2034770332","https://openalex.org/W2035330601","https://openalex.org/W2038168507","https://openalex.org/W2039152325","https://openalex.org/W2052250375","https://openalex.org/W2054088330","https://openalex.org/W2055774746","https://openalex.org/W2063139027","https://openalex.org/W2079455573","https://openalex.org/W2084147384","https://openalex.org/W2090597220","https://openalex.org/W2149079172","https://openalex.org/W2151934688","https://openalex.org/W2171517688","https://openalex.org/W2183336834","https://openalex.org/W2184968222","https://openalex.org/W2286255985","https://openalex.org/W2400045719","https://openalex.org/W2525001998","https://openalex.org/W2530833951","https://openalex.org/W2540347025","https://openalex.org/W2559212084","https://openalex.org/W2560663849","https://openalex.org/W2566932600","https://openalex.org/W2588123864","https://openalex.org/W2747918806","https://openalex.org/W2760821868","https://openalex.org/W2779962245","https://openalex.org/W2785150634","https://openalex.org/W2790726016","https://openalex.org/W2794691708","https://openalex.org/W2803410170","https://openalex.org/W2883884554","https://openalex.org/W2896293926","https://openalex.org/W2904687172","https://openalex.org/W2912743928","https://openalex.org/W2914414015","https://openalex.org/W2951672374","https://openalex.org/W2968836092","https://openalex.org/W2969551943","https://openalex.org/W2969829558","https://openalex.org/W2978230380","https://openalex.org/W2986643490","https://openalex.org/W3002843471","https://openalex.org/W3036538529","https://openalex.org/W3041076148","https://openalex.org/W3084131654","https://openalex.org/W3092924046","https://openalex.org/W3093018209","https://openalex.org/W3095900613","https://openalex.org/W3109143003","https://openalex.org/W3122270077","https://openalex.org/W3129287313","https://openalex.org/W3174105525","https://openalex.org/W3175140089","https://openalex.org/W3205629104","https://openalex.org/W3206905653","https://openalex.org/W4200569973","https://openalex.org/W4205403120","https://openalex.org/W4211168555","https://openalex.org/W4220924722","https://openalex.org/W4232393194"],"related_works":["https://openalex.org/W6920988948","https://openalex.org/W2791701803","https://openalex.org/W3212985269","https://openalex.org/W2760821868","https://openalex.org/W7166879944","https://openalex.org/W3179861433","https://openalex.org/W4388701550","https://openalex.org/W4413054564","https://openalex.org/W3119693934","https://openalex.org/W2566932600"],"abstract_inverted_index":{"Mechanosensitive":[0],"Piezo":[1,35,73,80],"ion":[2,36,74,81],"channels":[3,37,82],"were":[4,38],"first":[5],"reported":[6,112],"in":[7,9,40,87,117],"2010":[8],"a":[10,17,84],"mouse":[11],"neuroblastoma":[12],"cell":[13],"line,":[14],"opening":[15],"up":[16],"new":[18],"field":[19],"for":[20],"studying":[21],"the":[22,32,56,70,121,133],"composition":[23],"and":[24,47,64,91,93,100,119,123],"function":[25,92],"of":[26,58,72,115,126],"eukaryotic":[27],"mechanically":[28],"activated":[29],"channels.":[30,75],"During":[31],"past":[33],"decade,":[34],"identified":[39],"many":[41],"species,":[42],"such":[43,54],"as":[44,55],"bacteria,":[45],"Drosophila,":[46],"mammals.":[48],"In":[49,104],"mammals,":[50],"basic":[51],"life":[52],"activities,":[53],"sense":[57],"touch,":[59],"proprioception,":[60],"hearing,":[61],"vascular":[62,89],"development,":[63],"blood":[65],"pressure":[66],"regulation,":[67],"depend":[68],"on":[69,109,132],"activation":[71],"Cumulative":[76],"evidence":[77],"suggests":[78],"that":[79,111],"play":[83],"major":[85],"role":[86],"lung":[88],"development":[90],"diseases":[94],"like":[95],"pneumonia,":[96],"pulmonary":[97],"hypertension,":[98],"apnea,":[99],"other":[101],"lung-related":[102],"diseases.":[103],"this":[105],"review,":[106],"we":[107],"focused":[108],"studies":[110],"specific":[113],"functions":[114],"Piezos":[116],"tissues":[118],"emphasized":[120],"physiological":[122],"pathological":[124],"effects":[125],"their":[127],"absence":[128],"or":[129],"functional":[130],"mutations":[131],"respiratory":[134],"system.":[135]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-07-30T00:00:00"}