{"id":"https://openalex.org/W4288467893","doi":"https://doi.org/10.15252/rc.2022256824","title":"Author Reply to Peer Reviews of Population-level survey of loss-of-function mutations revealed that background dependent fitness genes are rare and functionally related in yeast","display_name":"Author Reply to Peer Reviews of Population-level survey of loss-of-function mutations revealed that background dependent fitness genes are rare and functionally related in yeast","publication_year":2022,"publication_date":"2022-01-19","ids":{"openalex":"https://openalex.org/W4288467893","doi":"https://doi.org/10.15252/rc.2022256824"},"language":"en","primary_location":{"id":"doi:10.15252/rc.2022256824","doi":"https://doi.org/10.15252/rc.2022256824","is_oa":false,"landing_page_url":"https://doi.org/10.15252/rc.2022256824","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Review Commons","raw_type":"peer-review"},"volume":null,"type":"peer-review","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091722749","display_name":"Joseph Schacherer","orcid":"https://orcid.org/0000-0002-6606-6884","observed_orcids":["https://orcid.org/0000-0002-6606-6884"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph Schacherer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078140086","display_name":"Jing Hou","orcid":"https://orcid.org/0000-0003-2940-9670","observed_orcids":["https://orcid.org/0000-0003-2940-9670","https://orcid.org/0000-0002-6600-5547"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jing Hou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030253221","display_name":"Marion Garin","orcid":"https://orcid.org/0009-0004-9034-5981","observed_orcids":["https://orcid.org/0009-0004-9034-5981"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marion Garin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082716004","display_name":"Arthur Jallet","orcid":"https://orcid.org/0000-0003-0709-2430","observed_orcids":["https://orcid.org/0000-0003-0709-2430"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arthur Jallet","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051713747","display_name":"Anne Friedrich","orcid":"https://orcid.org/0000-0003-3558-9356","observed_orcids":["https://orcid.org/0000-0003-3558-9356"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anne Friedrich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5031794194","display_name":"\u00c9lodie Caudal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elodie Caudal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.6366999745368958,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.6366999745368958,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.3312999904155731,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/loss-of-function-variants","display_name":"loss-of-function mutations","score":0.9980000257492065},{"id":"https://openalex.org/keywords/fitness-genes","display_name":"fitness genes","score":0.6759999990463257},{"id":"https://openalex.org/keywords/gene-function","display_name":"gene function","score":0.48500001430511475},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.8820000290870667},{"id":"https://openalex.org/keywords/population-genetics","display_name":"population genetics","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6031091809272766},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5605834126472473},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.48287633061408997},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.4813116788864136},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45809608697891235},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.45702195167541504},{"id":"https://openalex.org/C105951970","wikidata":"https://www.wikidata.org/wiki/Q1036748","display_name":"Loss function","level":4,"score":0.4356025457382202},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.13053297996520996},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.11921223998069763},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.10172015428543091}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.15252/rc.2022256824","doi":"https://doi.org/10.15252/rc.2022256824","is_oa":false,"landing_page_url":"https://doi.org/10.15252/rc.2022256824","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Review Commons","raw_type":"peer-review"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4294817651","https://openalex.org/W6920926234","https://openalex.org/W2025540524","https://openalex.org/W2030481412","https://openalex.org/W2159010915","https://openalex.org/W3210064813","https://openalex.org/W2808077797","https://openalex.org/W4366400963","https://openalex.org/W4304182916","https://openalex.org/W2611339556"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2022-07-29T00:00:00"}