{"id":"https://openalex.org/W4288069201","doi":"https://doi.org/10.1038/s41598-022-16062-0","title":"Applying machine learning and predictive modeling to retention and viral suppression in South African HIV treatment cohorts","display_name":"Applying machine learning and predictive modeling to retention and viral suppression in South African HIV treatment cohorts","publication_year":2022,"publication_date":"2022-07-26","ids":{"openalex":"https://openalex.org/W4288069201","doi":"https://doi.org/10.1038/s41598-022-16062-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/35882962","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9325703"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-022-16062-0","doi":"https://doi.org/10.1038/s41598-022-16062-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-022-16062-0","pdf_url":"https://www.nature.com/articles/s41598-022-16062-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-022-16062-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010315274","display_name":"Mhairi Maskew","orcid":"https://orcid.org/0000-0003-4238-0200","observed_orcids":["https://orcid.org/0000-0003-4238-0200"]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":true,"raw_author_name":"Mhairi Maskew","raw_affiliation_strings":["Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa. mmaskew@heroza.org","Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa. mmaskew@heroza.org","institution_ids":["https://openalex.org/I192619145"]},{"raw_affiliation_string":"Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018293562","display_name":"Kieran Sharpey-Schafer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kieran Sharpey-Schafer","raw_affiliation_strings":["Palindrome Data, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Palindrome Data, Cape Town, South Africa","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000913535","display_name":"Lucien De Voux","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lucien De Voux","raw_affiliation_strings":["Palindrome Data, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Palindrome Data, Cape Town, South Africa","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048445509","display_name":"Thomas Crompton","orcid":"https://orcid.org/0000-0001-5525-3468","observed_orcids":["https://orcid.org/0000-0001-5525-3468"]},"institutions":[{"id":"https://openalex.org/I4210159080","display_name":"Right to Care","ror":"https://ror.org/052gvyf59","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210159080"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Thomas Crompton","raw_affiliation_strings":["Right to Care, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Right to Care, Johannesburg, South Africa","institution_ids":["https://openalex.org/I4210159080"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039166958","display_name":"Jacob H. Bor","orcid":"https://orcid.org/0000-0002-5112-8536","observed_orcids":["https://orcid.org/0000-0002-5112-8536"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["US","ZA"],"is_corresponding":false,"raw_author_name":"Jacob Bor","raw_affiliation_strings":["Department of Epidemiology, Boston University School of Public Health, Boston University, Boston, USA","Department of Global Health, Boston University School of Public Health, Boston University, Boston, USA","Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Boston University School of Public Health, Boston University, Boston, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Global Health, Boston University School of Public Health, Boston University, Boston, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075054171","display_name":"Marcus Rennick","orcid":"https://orcid.org/0000-0002-2005-356X","observed_orcids":["https://orcid.org/0000-0002-2005-356X"]},"institutions":[{"id":"https://openalex.org/I4210159080","display_name":"Right to Care","ror":"https://ror.org/052gvyf59","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210159080"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Marcus Rennick","raw_affiliation_strings":["Right to Care, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Right to Care, Johannesburg, South Africa","institution_ids":["https://openalex.org/I4210159080"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053929014","display_name":"Admire Chirowodza","orcid":"https://orcid.org/0000-0003-0983-3685","observed_orcids":["https://orcid.org/0000-0003-0983-3685"]},"institutions":[{"id":"https://openalex.org/I4210159080","display_name":"Right to Care","ror":"https://ror.org/052gvyf59","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210159080"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Admire Chirowodza","raw_affiliation_strings":["Right to Care, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Right to Care, Johannesburg, South Africa","institution_ids":["https://openalex.org/I4210159080"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060591178","display_name":"Jacqui Miot","orcid":"https://orcid.org/0000-0001-7070-3826","observed_orcids":["https://orcid.org/0000-0001-7070-3826"]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Jacqui Miot","raw_affiliation_strings":["Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089006910","display_name":"Seithati Molefi","orcid":"https://orcid.org/0000-0003-2572-0883","observed_orcids":["https://orcid.org/0000-0003-2572-0883"]},"institutions":[{"id":"https://openalex.org/I4210159080","display_name":"Right to Care","ror":"https://ror.org/052gvyf59","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210159080"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Seithati Molefi","raw_affiliation_strings":["Right to Care, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Right to Care, Johannesburg, South Africa","institution_ids":["https://openalex.org/I4210159080"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045602485","display_name":"Chuka Onaga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159080","display_name":"Right to Care","ror":"https://ror.org/052gvyf59","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210159080"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Chuka Onaga","raw_affiliation_strings":["Right to Care, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Right to Care, Johannesburg, South Africa","institution_ids":["https://openalex.org/I4210159080"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023883566","display_name":"Pappie Majuba","orcid":"https://orcid.org/0000-0002-6197-1850","observed_orcids":["https://orcid.org/0000-0002-6197-1850"]},"institutions":[{"id":"https://openalex.org/I4210159080","display_name":"Right to Care","ror":"https://ror.org/052gvyf59","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210159080"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Pappie Majuba","raw_affiliation_strings":["Right to Care, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Right to Care, Johannesburg, South Africa","institution_ids":["https://openalex.org/I4210159080"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051991963","display_name":"Ian Sanne","orcid":"https://orcid.org/0000-0003-4921-5611","observed_orcids":["https://orcid.org/0000-0003-4921-5611"]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]},{"id":"https://openalex.org/I4210159080","display_name":"Right to Care","ror":"https://ror.org/052gvyf59","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210159080"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Ian Sanne","raw_affiliation_strings":["Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa","Right to Care, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, 39 Empire Road, Parktown, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]},{"raw_affiliation_string":"Right to Care, Johannesburg, South Africa","institution_ids":["https://openalex.org/I4210159080"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074320126","display_name":"Pedro Terrence Pisa","orcid":"https://orcid.org/0000-0001-5188-5660","observed_orcids":["https://orcid.org/0000-0001-5188-5660"]},"institutions":[{"id":"https://openalex.org/I4210159080","display_name":"Right to Care","ror":"https://ror.org/052gvyf59","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210159080"]},{"id":"https://openalex.org/I69552723","display_name":"University of Pretoria","ror":"https://ror.org/00g0p6g84","country_code":"ZA","type":"education","lineage":["https://openalex.org/I69552723"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Pedro Pisa","raw_affiliation_strings":["Department of Human Nutrition and Dietetics, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa","Right to Care, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Nutrition and Dietetics, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa","institution_ids":["https://openalex.org/I69552723"]},{"raw_affiliation_string":"Right to Care, Johannesburg, South Africa","institution_ids":["https://openalex.org/I4210159080"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5010315274"],"corresponding_institution_ids":["https://openalex.org/I192619145"],"apc_list":{"value":2190,"currency":"USD","value_usd":2190},"apc_paid":{"value":2190,"currency":"USD","value_usd":2190},"fwci":6.7293,"has_fulltext":true,"cited_by_count":74,"citation_normalized_percentile":{"value":0.98071199,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"12","issue":"1","first_page":"12715","last_page":"12715"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11860","display_name":"HIV, Drug Use, Sexual Risk","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv","display_name":"HIV","score":0.746999979019165},{"id":"https://openalex.org/keywords/retention-in-care","display_name":"retention in care","score":0.8429999947547913},{"id":"https://openalex.org/keywords/loss-to-follow-up","display_name":"loss to follow-up","score":0.843999981880188},{"id":"https://openalex.org/keywords/viral-suppression","display_name":"viral suppression","score":0.824999988079071},{"id":"https://openalex.org/keywords/hiv-viral-load","display_name":"HIV viral load","score":0.7289999723434448},{"id":"https://openalex.org/keywords/predictive-modeling","display_name":"predictive modeling","score":0.6740000247955322},{"id":"https://openalex.org/keywords/risk-score","display_name":"risk score","score":0.7099999785423279},{"id":"https://openalex.org/keywords/south-africa","display_name":"South Africa","score":0.5049999952316284},{"id":"https://openalex.org/keywords/differentiated-service-delivery","display_name":"differentiated service delivery","score":0.5619999766349792},{"id":"https://openalex.org/keywords/machine-learning","display_name":"machine learning","score":0.414000004529953}],"concepts":[{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.6567128896713257},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.5732485055923462},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.4804475009441376},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4375345706939697},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.412035197019577},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37296050786972046},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3287758231163025},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32257184386253357}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013019","descriptor_name":"South Africa","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1038/s41598-022-16062-0","doi":"https://doi.org/10.1038/s41598-022-16062-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-022-16062-0","pdf_url":"https://www.nature.com/articles/s41598-022-16062-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"doi:10.1101/2021.02.03.21251100","doi":"https://doi.org/10.1101/2021.02.03.21251100","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.02.03.21251100","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2021/02/05/2021.02.03.21251100.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:35882962","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35882962","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9325703","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9325703/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:8be61d8f279149edba5fa97ed0877053","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/8be61d8f279149edba5fa97ed0877053","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)","raw_type":"article"},{"id":"pmh:oai:repository.up.ac.za:2263/88448","doi":null,"is_oa":true,"landing_page_url":"https://repository.up.ac.za/handle/2263/88448","pdf_url":null,"source":{"id":"https://openalex.org/S4306401870","display_name":"UpSpace Institutional Repository (University of Pretoria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I69552723","host_organization_name":"University of Pretoria","host_organization_lineage":["https://openalex.org/I69552723"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1038/s41598-022-16062-0","doi":"https://doi.org/10.1038/s41598-022-16062-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-022-16062-0","pdf_url":"https://www.nature.com/articles/s41598-022-16062-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G3350995662","display_name":"The South African National HIV Pregnancy Cohort: evaluating continuity of care among women living with HIV","funder_award_id":"R01HD103466","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G3455851093","display_name":"IMPLEMENTATION OF THE HIV/AIDS CARE AND TREATMENT ACTIVITIES UNDER PEPFAR IN SA.","funder_award_id":"72067418CA00029","funder_id":"https://openalex.org/F4320306115","funder_display_name":"United States Agency for International Development"},{"id":"https://openalex.org/G4805387653","display_name":"Evaluating UTT with a National HIV Cohort to Optimize South Africa's HIV Response (ENCORE)","funder_award_id":"R01AI152149","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306115","display_name":"United States Agency for International Development","ror":"https://ror.org/01n6e6j62"},{"id":"https://openalex.org/F4320310979","display_name":"U.S. President\u2019s Emergency Plan for AIDS Relief","ror":"https://ror.org/025g6sc95"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4288069201.pdf","grobid_xml":"https://content.openalex.org/works/W4288069201.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1514644537","https://openalex.org/W1531725059","https://openalex.org/W1964421503","https://openalex.org/W1988790447","https://openalex.org/W2037678368","https://openalex.org/W2101234009","https://openalex.org/W2120637537","https://openalex.org/W2152505869","https://openalex.org/W2158698691","https://openalex.org/W2244501064","https://openalex.org/W2314461521","https://openalex.org/W2344725745","https://openalex.org/W2396233551","https://openalex.org/W2405773499","https://openalex.org/W2439568532","https://openalex.org/W2606992833","https://openalex.org/W2613869537","https://openalex.org/W2808068978","https://openalex.org/W2899669642","https://openalex.org/W2943039121","https://openalex.org/W2975202634","https://openalex.org/W2995562455","https://openalex.org/W3026374985","https://openalex.org/W3035999516","https://openalex.org/W3045731716","https://openalex.org/W4254292474"],"related_works":["https://openalex.org/W4384819097","https://openalex.org/W4400028627","https://openalex.org/W4301367396","https://openalex.org/W4408636222","https://openalex.org/W3015836481","https://openalex.org/W7144342781","https://openalex.org/W4389427222","https://openalex.org/W4404524825","https://openalex.org/W4399331008","https://openalex.org/W4402800991"],"abstract_inverted_index":{"HIV":[0,24,60,329],"treatment":[1,288,355],"programs":[2],"face":[3],"challenges":[4],"in":[5,30,72,170,192,198,234,251],"identifying":[6],"patients":[7,189,238,330,352],"at":[8,87,211,244,296,331],"risk":[9,37,332],"for":[10,39,102,167,209,218,312,333],"loss-to-follow-up":[11],"and":[12,54,67,84,98,117,129,153,176,180,196,239,287,300,335,359],"uncontrolled":[13],"viremia.":[14],"We":[15,34],"applied":[16],"predictive":[17,104,178,203],"machine":[18],"learning":[19,326],"algorithms":[20,93],"to":[21,150,216],"anonymised,":[22],"patient-level":[23],"programmatic":[25],"data":[26,69,142],"from":[27,132,143,207,354],"two":[28,40],"districts":[29],"South":[31],"Africa,":[32],"2016-2018.":[33],"developed":[35],"patient":[36,361],"scores":[38],"outcomes:":[41],"(1)":[42],"visit":[43,53,83,215,230],"attendance":[44,210],"\u2264":[45],"28":[46],"days":[47],"of":[48,57,78,127,172,236,254,262,270,280,294,303,320,344,349],"the":[49,58,80,88,134,144,151,183,193,199,212,223,241,245,292,297,301,304,318,321,342],"next":[50,59,81,89,213,246,305],"scheduled":[51,82,214,229],"clinic":[52],"(2)":[55],"suppression":[56],"viral":[61],"load":[62],"(VL).":[63],"Demographic,":[64],"clinical,":[65],"behavioral":[66],"laboratory":[68],"were":[70,100,107,148,190,259,308],"investigated":[71],"multiple":[73],"models":[74,348],"as":[75],"predictor":[76,140],"variables":[77],"attending":[79],"VL":[85,200,219,242,272,313,323],"results":[86],"test.":[90],"Three":[91],"classification":[92,135],"(logistical":[94],"regression,":[95],"random":[96],"forest":[97],"AdaBoost)":[99],"evaluated":[101],"building":[103],"models.":[105],"Data":[106],"randomly":[108],"sampled":[109],"on":[110,282],"a":[111,115,124,228],"70/30":[112],"split":[113],"into":[114],"training":[116,121],"test":[118,146,247],"set.":[119],"The":[120,139,202],"set":[122,126,147],"included":[123,191,265,317],"balanced":[125],"positive":[128,175],"negative":[130,177],"examples":[131],"which":[133],"algorithm":[136],"could":[137],"learn.":[138],"variable":[141],"unseen":[145],"given":[149],"model,":[152],"each":[154,168],"predicted":[155],"outcome":[156],"was":[157],"scored":[158],"against":[159],"known":[160],"outcomes.":[161,362],"Finally,":[162],"we":[163],"estimated":[164],"performance":[165],"metrics":[166],"model":[169,195,224],"terms":[171],"sensitivity,":[173],"specificity,":[174],"value":[179],"area":[181],"under":[182],"curve":[184],"(AUC).":[185],"In":[186],"total,":[187],"445,636":[188],"retention":[194],"363,977":[197],"model.":[201],"metric":[204],"(AUC)":[205],"ranged":[206],"0.69":[208],"0.76":[217],"suppression,":[220,314],"suggesting":[221],"that":[222,258],"correctly":[225],"classified":[226],"whether":[227,240],"would":[231,248],"be":[232,249],"attended":[233],"2":[235],"3":[237,253],"result":[243],"suppressed":[250],"approximately":[252],"4":[255],"patients.":[256],"Variables":[257],"important":[260],"predictors":[261,316],"both":[263],"outcomes":[264],"prior":[266,271],"late":[267],"visits,":[268],"number":[269,279,293],"tests,":[273],"time":[274],"since":[275],"their":[276,283],"last":[277],"visit,":[278],"visits":[281,295],"current":[284,298],"regimen,":[285],"age,":[286],"duration.":[289],"For":[290],"retention,":[291],"facility":[299],"details":[302],"appointment":[306],"date":[307],"also":[309],"predictors,":[310],"while":[311],"other":[315],"range":[319],"previous":[322],"value.":[324],"Machine":[325],"can":[327,340],"identify":[328],"disengagement":[334],"unsuppressed":[336],"VL.":[337],"Predictive":[338],"modeling":[339],"improve":[341],"targeting":[343],"interventions":[345],"through":[346],"differentiated":[347],"care":[350],"before":[351],"disengage":[353],"programmes,":[356],"increasing":[357],"cost-effectiveness":[358],"improving":[360]},"counts_by_year":[{"year":2026,"cited_by_count":21},{"year":2025,"cited_by_count":32},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-07-28T00:00:00"}