{"id":"https://openalex.org/W4287541245","doi":null,"title":"Impact of Clinical and Genomic Factors on COVID-19 Disease Severity.","display_name":"Impact of Clinical and Genomic Factors on COVID-19 Disease Severity.","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W4287541245","pmid":"https://pubmed.ncbi.nlm.nih.gov/35308982","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8861728"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8861728","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8861728","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Annu Symp Proc","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8861728","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Sanjoy Dey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sanjoy Dey","raw_affiliation_strings":["Center for Computational Health, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Health, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Aritra Bose","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aritra Bose","raw_affiliation_strings":["Computational Genomics, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Genomics, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Subrata Saha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Subrata Saha","raw_affiliation_strings":["Columbia University Irving Medical Center, Columbia University, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University Irving Medical Center, Columbia University, NY, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Prithwish Chakraborty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prithwish Chakraborty","raw_affiliation_strings":["Center for Computational Health, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Health, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mohamed Ghalwash","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohamed Ghalwash","raw_affiliation_strings":["Center for Computational Health, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Health, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Aldo Guzm X E N-S\u00e1enz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aldo Guzm X E N-S\u00e1enz","raw_affiliation_strings":["Computational Genomics, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Genomics, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Filippo Utro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Filippo Utro","raw_affiliation_strings":["Computational Genomics, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Genomics, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kenney Ng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenney Ng","raw_affiliation_strings":["Center for Computational Health, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Health, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jianying Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianying Hu","raw_affiliation_strings":["Center for Computational Health, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Health, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Laxmi Parida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laxmi Parida","raw_affiliation_strings":["Computational Genomics, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Genomics, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]},{"author_position":"last","author":{"id":null,"display_name":"Daby Sow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341412227","display_name":"IBM (United States)","ror":"https://ror.org/05hh8d621","country_code":"US","type":"company","lineage":["https://openalex.org/I1341412227"]},{"id":"https://openalex.org/I4210114115","display_name":"IBM Research - Thomas J. Watson Research Center","ror":"https://ror.org/0265w5591","country_code":"US","type":"facility","lineage":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daby Sow","raw_affiliation_strings":["Center for Computational Health, IBM Research, Yorktown Heights, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Health, IBM Research, Yorktown Heights, NY, USA","institution_ids":["https://openalex.org/I1341412227","https://openalex.org/I4210114115"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3361,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.63073441,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"2021","issue":null,"first_page":"378","last_page":"387"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.6518999934196472,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.6518999934196472,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.19140000641345978,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.08470000326633453,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.8970000147819519},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.9869999885559082},{"id":"https://openalex.org/keywords/host-genome","display_name":"host genome","score":0.7300000190734863},{"id":"https://openalex.org/keywords/clinical-factors","display_name":"clinical factors","score":0.6119999885559082},{"id":"https://openalex.org/keywords/sars-cov-2-variants","display_name":"SARS-CoV-2 variants","score":0.8539999723434448},{"id":"https://openalex.org/keywords/b-1-1-7-alpha-variant","display_name":"B.1.1.7 Alpha variant","score":0.9490000009536743},{"id":"https://openalex.org/keywords/positive-unlabeled-learning","display_name":"positive-unlabeled learning","score":0.8679999709129333},{"id":"https://openalex.org/keywords/uk-biobank","display_name":"UK Biobank","score":0.9509999752044678},{"id":"https://openalex.org/keywords/biological-pathways","display_name":"biological pathways","score":0.7289999723434448},{"id":"https://openalex.org/keywords/treatment-protocols","display_name":"treatment protocols","score":0.6460000276565552}],"concepts":[{"id":"https://openalex.org/C116567970","wikidata":"https://www.wikidata.org/wiki/Q864217","display_name":"Biobank","level":2,"score":0.7159751057624817},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.646163284778595},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.6438602209091187},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.48051580786705017},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.47331249713897705},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4627980887889862},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.4166058897972107},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3613627851009369},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35752612352371216},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3561124801635742},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3462282419204712},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21546602249145508},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.14242979884147644},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11258265376091003},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10860195755958557}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:8861728","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8861728","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Annu Symp Proc","raw_type":"Text"},{"id":"pmid:35308982","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35308982","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA ... Annual Symposium proceedings. AMIA Symposium","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8861728","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8861728","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Annu Symp Proc","raw_type":"Text"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W2035618305","https://openalex.org/W2038257917","https://openalex.org/W2069411599","https://openalex.org/W2082704080","https://openalex.org/W2095699364","https://openalex.org/W2099085143","https://openalex.org/W2152575748","https://openalex.org/W2165465489","https://openalex.org/W2938965511","https://openalex.org/W2950099124","https://openalex.org/W3013619034","https://openalex.org/W3014994762","https://openalex.org/W3016010853","https://openalex.org/W3019336370","https://openalex.org/W3020646040","https://openalex.org/W3023991776","https://openalex.org/W3028410545","https://openalex.org/W3036779511","https://openalex.org/W3036942428","https://openalex.org/W3041449126","https://openalex.org/W3041494167","https://openalex.org/W3042860993","https://openalex.org/W3043177992","https://openalex.org/W3047144258","https://openalex.org/W3047343217","https://openalex.org/W3048804923","https://openalex.org/W3080441768","https://openalex.org/W3082060340","https://openalex.org/W3090928025","https://openalex.org/W3091975903","https://openalex.org/W3094438226","https://openalex.org/W3104557298","https://openalex.org/W3112105690","https://openalex.org/W3132982761","https://openalex.org/W3156430862"],"related_works":["https://openalex.org/W3138037804","https://openalex.org/W7213204304","https://openalex.org/W4200324449","https://openalex.org/W4360608821","https://openalex.org/W3104557298","https://openalex.org/W7162492955","https://openalex.org/W4307564059","https://openalex.org/W4221101236","https://openalex.org/W6965122115","https://openalex.org/W4377696055"],"abstract_inverted_index":{"To":[0],"date,":[1],"there":[2],"have":[3],"been":[4],"180":[5],"million":[6,15],"confirmed":[7],"cases":[8],"of":[9,28,42,84,143],"COVID-19,":[10],"with":[11,36,54],"more":[12],"than":[13],"3.8":[14],"deaths,":[16],"reported":[17],"to":[18,79,120],"WHO":[19],"worldwide.":[20],"In":[21],"this":[22],"paper":[23],"we":[24,65],"address":[25],"the":[26,30,40,46,70,81,85,110],"problem":[27],"understanding":[29,109],"host":[31],"genome's":[32],"influence,":[33],"in":[34,45,108,133],"concert":[35],"clinical":[37,135,144],"variables,":[38],"on":[39,61,69,91],"severity":[41],"COVID-19":[43],"manifestation":[44],"patient.":[47],"Leveraging":[48],"positive-unlabeled":[49],"machine":[50],"learning":[51],"algorithms":[52],"coupled":[53],"RubricOE,":[55],"a":[56,122,140],"state-of-the-art":[57],"genomic":[58,99,137,146],"analysis":[59],"framework,":[60],"UK":[62],"BioBank":[63],"data":[64,138],"extract":[66],"novel":[67],"insights":[68],"complex":[71],"interplay.":[72],"The":[73,98],"algorithm":[74],"is":[75,118],"also":[76,101],"sensitive":[77,125],"enough":[78],"detect":[80],"changing":[82,95],"influence":[83],"emergent":[86],"B.1.1.7":[87],"SARS-CoV-2":[88],"(alpha)":[89],"variant":[90],"disease":[92,111],"severity,":[93],"and,":[94],"treatment":[96],"protocols.":[97],"component":[100],"implicates":[102],"biological":[103],"pathways":[104],"that":[105,116],"can":[106],"help":[107],"etiology.":[112],"Our":[113],"work":[114],"demonstrates":[115],"it":[117],"possible":[119],"build":[121],"robust":[123],"and":[124,131,136,145],"model":[126],"despite":[127],"significant":[128],"bias,":[129],"noise":[130],"incompleteness":[132],"both":[134],"by":[139],"careful":[141],"interleaving":[142],"methodologies.":[147]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-07-25T00:00:00"}
