{"id":"https://openalex.org/W4287400672","doi":null,"title":"Detection of locomotion deficit in a post-traumatic syringomyelia rat model using automated gait analysis technique","display_name":"Detection of locomotion deficit in a post-traumatic syringomyelia rat model using automated gait analysis technique","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W4287400672"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:1d67e249d65a4ba983f05e0c1dc5f9da","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1d67e249d65a4ba983f05e0c1dc5f9da","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 16, Iss 11 (2021)","raw_type":"article"},"volume":null,"type":"article","indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/1d67e249d65a4ba983f05e0c1dc5f9da","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090793831","display_name":"Dipak D. Pukale","orcid":"https://orcid.org/0000-0001-9731-0301","observed_orcids":["https://orcid.org/0000-0001-9731-0301"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dipak D. Pukale","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114026137","display_name":"Mahmoud Farrag","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mahmoud Farrag","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5017899525","display_name":"Nic D. Leipzig","orcid":"https://orcid.org/0000-0002-6356-7691","observed_orcids":["https://orcid.org/0000-0002-6356-7691"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nic D. Leipzig","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.31313815,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.9150000214576721,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.9150000214576721,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12249","display_name":"Veterinary Orthopedics and Neurology","score":0.04610000178217888,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11833","display_name":"Spinal Dysraphism and Malformations","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/post-traumatic-syringomyelia","display_name":"post-traumatic syringomyelia","score":0.9900000095367432},{"id":"https://openalex.org/keywords/locomotion-deficits","display_name":"locomotion deficits","score":0.906000018119812},{"id":"https://openalex.org/keywords/automated-gait-analysis","display_name":"automated gait analysis","score":0.9330000281333923},{"id":"https://openalex.org/keywords/agatha","display_name":"Agatha","score":0.8330000042915344},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.671999990940094},{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"spinal cord injury","score":0.9279999732971191},{"id":"https://openalex.org/keywords/syrinx-formation","display_name":"syrinx formation","score":0.7089999914169312},{"id":"https://openalex.org/keywords/gait-parameters","display_name":"gait parameters","score":0.6480000019073486},{"id":"https://openalex.org/keywords/stride-length","display_name":"stride length","score":0.5690000057220459},{"id":"https://openalex.org/keywords/duty-cycle","display_name":"duty cycle","score":0.7310000061988831},{"id":"https://openalex.org/keywords/phase-dispersion","display_name":"phase dispersion","score":0.49399998784065247}],"concepts":[{"id":"https://openalex.org/C151800584","wikidata":"https://www.wikidata.org/wiki/Q2370000","display_name":"Gait","level":2,"score":0.6605097055435181},{"id":"https://openalex.org/C2777836068","wikidata":"https://www.wikidata.org/wiki/Q1112977","display_name":"Syringomyelia","level":3,"score":0.6549994945526123},{"id":"https://openalex.org/C173906292","wikidata":"https://www.wikidata.org/wiki/Q1493441","display_name":"Gait analysis","level":3,"score":0.6412409543991089},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.5285243988037109},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.39196401834487915},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3404642343521118},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2633606791496277},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.26190775632858276},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.0857749879360199}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:doaj.org/article:1d67e249d65a4ba983f05e0c1dc5f9da","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1d67e249d65a4ba983f05e0c1dc5f9da","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 16, Iss 11 (2021)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:1d67e249d65a4ba983f05e0c1dc5f9da","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1d67e249d65a4ba983f05e0c1dc5f9da","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 16, Iss 11 (2021)","raw_type":"article"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1990840758","https://openalex.org/W4402575782","https://openalex.org/W7133208334","https://openalex.org/W6889991229","https://openalex.org/W2020473287","https://openalex.org/W2313049429","https://openalex.org/W2910472010","https://openalex.org/W2491025662","https://openalex.org/W2276939578","https://openalex.org/W7128521154"],"abstract_inverted_index":{"Syringomyelia":[0],"(SM)":[1],"is":[2],"a":[3,9],"spinal":[4,18],"cord":[5,19],"disorder":[6],"in":[7,16,21,71,111,135,178],"which":[8,176],"cyst":[10],"(syrinx)":[11],"filled":[12],"with":[13,92,173],"fluid":[14],"forms":[15],"the":[17,48,61,78,105],"post-injury/disease,":[20],"patients":[22],"syrinx":[23,69],"symptoms":[24],"include":[25],"loss":[26],"of":[27,51,55,63,82,104,137],"pain":[28],"and":[29,42,86,98,149,168],"temperature":[30],"sensation":[31],"or":[32],"locomotion":[33,65,120,133,170,187],"deficit.":[34],"Currently,":[35],"there":[36],"are":[37],"no":[38],"small":[39],"animal":[40],"models":[41],"connected":[43],"tools":[44],"to":[45,59,68,154,158,185],"help":[46],"study":[47,57],"functional":[49],"impacts":[50],"SM.":[52,159,194],"The":[53],"objective":[54],"this":[56,163],"was":[58],"determine":[60],"detectability":[62],"subtle":[64,169],"deficits":[66,134,171],"due":[67,157],"formation/expansion":[70],"post-traumatic":[72],"syringomyelia":[73],"(PTSM)":[74],"rat":[75],"model":[76],"using":[77,125],"recently":[79],"reported":[80],"method":[81],"Gait":[83,94],"Analysis":[84,95],"Instrumentation,":[85],"Technology":[87],"Optimized":[88],"for":[89,193],"Rodents":[90],"(GAITOR)":[91],"Automated":[93],"Through":[96],"Hues":[97],"Areas":[99],"(AGATHA)":[100],"technique.":[101],"First":[102],"videos":[103,124],"rats":[106,130,156],"were":[107],"collected":[108,123],"while":[109],"walking":[110],"an":[112],"arena":[113],"(using":[114],"GAITOR)":[115],"followed":[116],"by":[117],"extracting":[118],"meaningful":[119],"information":[121],"from":[122],"AGATHA":[126],"protocol.":[127],"PTSM":[128,174],"injured":[129],"demonstrated":[131],"detectable":[132],"terms":[136],"duty":[138],"factor":[139],"imbalance,":[140],"paw":[141],"placement":[142],"accuracy,":[143],"step":[144],"contact":[145],"width,":[146],"stride":[147],"length,":[148],"phase":[150],"dispersion":[151],"parameters":[152],"compared":[153],"uninjured":[155],"We":[160],"concluded":[161],"that":[162],"technique":[164],"could":[165,181],"detect":[166],"mild":[167],"associated":[172],"injury,":[175],"also":[177],"future":[179],"work":[180],"be":[182],"used":[183],"further":[184],"monitor":[186],"responses":[188],"after":[189],"different":[190],"treatment":[191],"strategies":[192]},"counts_by_year":[],"updated_date":"2026-05-06T06:10:43.113611","created_date":"2022-07-25T00:00:00"}