{"id":"https://openalex.org/W4286853418","doi":"https://doi.org/10.3791/50087-v","title":"Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization","display_name":"Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization","publication_year":2013,"publication_date":"2013-02-03","ids":{"openalex":"https://openalex.org/W4286853418","doi":"https://doi.org/10.3791/50087-v"},"language":"en","primary_location":{"id":"doi:10.3791/50087-v","doi":"https://doi.org/10.3791/50087-v","is_oa":false,"landing_page_url":"https://doi.org/10.3791/50087-v","pdf_url":null,"source":{"id":"https://openalex.org/S199738284","display_name":"Journal of Visualized Experiments","issn_l":"1940-087X","issn":["1940-087X","2834-8400"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320416","host_organization_name":"MyJOVE","host_organization_lineage":["https://openalex.org/P4310320416"],"host_organization_lineage_names":["MyJOVE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Visualized Experiments","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084986744","display_name":"Julie Chaumeil","orcid":"https://orcid.org/0000-0002-8976-2890","observed_orcids":["https://orcid.org/0000-0002-8976-2890"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Julie Chaumeil","raw_affiliation_strings":["Department of Pathology, New York University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, New York University School of Medicine","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075638246","display_name":"Mariann Micsinai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802730090","display_name":"Yale Cancer Center","ror":"https://ror.org/03j7sze86","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802730090","https://openalex.org/I4210117499","https://openalex.org/I4210165192"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mariann Micsinai","raw_affiliation_strings":["Department of Pathology and Yale Cancer Center, Yale University School of Medicine","Department of Pathology, New York University School of Medicine","NYU Cancer Institute","New York University Center for Health Informatics and Bioinformatics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Yale Cancer Center, Yale University School of Medicine","institution_ids":["https://openalex.org/I2802730090","https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Pathology, New York University School of Medicine","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"NYU Cancer Institute","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York University Center for Health Informatics and Bioinformatics","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083464518","display_name":"Jane A. Skok","orcid":"https://orcid.org/0000-0002-4145-1516","observed_orcids":["https://orcid.org/0000-0002-4145-1516"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane A. Skok","raw_affiliation_strings":["Department of Pathology, New York University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, New York University School of Medicine","institution_ids":["https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5084986744"],"corresponding_institution_ids":["https://openalex.org/I57206974"],"apc_list":null,"apc_paid":null,"fwci":0.2983,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.62634959,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":"72","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.8184000253677368,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.8184000253677368,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.16169999539852142,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/3d-nuclear-organization","display_name":"3D nuclear organization","score":0.949999988079071},{"id":"https://openalex.org/keywords/interphase-nucleus","display_name":"interphase nuclei","score":0.949999988079071},{"id":"https://openalex.org/keywords/immunofluorescence","display_name":"immunofluorescence","score":0.8899999856948853},{"id":"https://openalex.org/keywords/chromatin-organization","display_name":"chromatin organization","score":0.5299999713897705},{"id":"https://openalex.org/keywords/nuclear-organization","display_name":"nuclear organization","score":0.5059999823570251}],"concepts":[{"id":"https://openalex.org/C29452124","wikidata":"https://www.wikidata.org/wiki/Q835950","display_name":"Interphase","level":2,"score":0.7465024590492249},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.7098585367202759},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.5563917756080627},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48123741149902344},{"id":"https://openalex.org/C115960442","wikidata":"https://www.wikidata.org/wiki/Q769863","display_name":"Nuclear DNA","level":4,"score":0.4681898355484009},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4658454656600952},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.44140517711639404},{"id":"https://openalex.org/C2780114586","wikidata":"https://www.wikidata.org/wiki/Q40260","display_name":"Cell nucleus","level":3,"score":0.4409509301185608},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.3651157319545746},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3427392840385437},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.23261457681655884},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20998242497444153},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.15347406268119812},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1370827555656433},{"id":"https://openalex.org/C24586158","wikidata":"https://www.wikidata.org/wiki/Q27075","display_name":"Mitochondrial DNA","level":3,"score":0.10264906287193298},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.07487267255783081}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3791/50087-v","doi":"https://doi.org/10.3791/50087-v","is_oa":false,"landing_page_url":"https://doi.org/10.3791/50087-v","pdf_url":null,"source":{"id":"https://openalex.org/S199738284","display_name":"Journal of Visualized Experiments","issn_l":"1940-087X","issn":["1940-087X","2834-8400"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320416","host_organization_name":"MyJOVE","host_organization_lineage":["https://openalex.org/P4310320416"],"host_organization_lineage_names":["MyJOVE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Visualized Experiments","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1203045427","display_name":"IGERT: Program in Computational Biology (COB)","funder_award_id":"0333389","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306155","display_name":"Cancer Research Institute","ror":"https://ror.org/02f3xk561"},{"id":"https://openalex.org/F4320337368","display_name":"Division of Graduate Education","ror":"https://ror.org/00whkrf32"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1531780147","https://openalex.org/W1567815100","https://openalex.org/W1968554285","https://openalex.org/W1977339483","https://openalex.org/W1980023815","https://openalex.org/W1985918588","https://openalex.org/W1993570130","https://openalex.org/W1999155341","https://openalex.org/W1999287382","https://openalex.org/W2004271214","https://openalex.org/W2042398661","https://openalex.org/W2046857826","https://openalex.org/W2046926525","https://openalex.org/W2057996703","https://openalex.org/W2060528836","https://openalex.org/W2077665121","https://openalex.org/W2082792824","https://openalex.org/W2083260329","https://openalex.org/W2084998277","https://openalex.org/W2098549100","https://openalex.org/W2102076165","https://openalex.org/W2106962105","https://openalex.org/W2107243811","https://openalex.org/W2108702314","https://openalex.org/W2110065044","https://openalex.org/W2118049302","https://openalex.org/W2123431252","https://openalex.org/W2125692751","https://openalex.org/W2128313472","https://openalex.org/W2128680272","https://openalex.org/W2138278453","https://openalex.org/W2140173610","https://openalex.org/W2146427646","https://openalex.org/W2152810593","https://openalex.org/W2179153589","https://openalex.org/W4255375128"],"related_works":["https://openalex.org/W2179153589","https://openalex.org/W143890695","https://openalex.org/W2128313472","https://openalex.org/W2058002233","https://openalex.org/W7099921647","https://openalex.org/W2765329479","https://openalex.org/W2098078667","https://openalex.org/W2911282524","https://openalex.org/W2462244505","https://openalex.org/W2945800668"],"abstract_inverted_index":{"Combined":[0],"Immunofluorescence":[1],"And":[2],"Dna":[3],"Fish":[4],"On":[5],"3d-preserved":[6],"Interphase":[7],"Nuclei":[8],"To":[9],"Study":[10],"Changes":[11],"In":[12],"3d":[13],"Nuclear":[14],"Organization":[15],"-":[16],"Video.":[17],"JoVE":[18,37,75],"publishes":[19],"peer-reviewed":[20],"scientific":[21,34,52,54],"video":[22,35],"protocols":[23],"to":[24,50],"accelerate":[25],"biological,":[26],"medical,":[27],"chemical":[28],"and":[29,42,56,62,70,80],"physical":[30],"research.":[31],"Watch":[32],"our":[33],"articles.":[36],"is":[38],"the":[39,48],"world-leading":[40],"producer":[41],"provider":[43],"of":[44,59,66],"science":[45],"videos":[46],"with":[47],"mission":[49],"improve":[51],"research,":[53,78],"journals,":[55],"education.":[57],"Millions":[58],"scientists,":[60],"educators":[61],"students":[63],"at":[64],"thousands":[65],"universities,":[67],"colleges,":[68],"hospitals":[69],"biopharmaceutical":[71],"companies":[72],"worldwide":[73],"use":[74],"for":[76],"their":[77],"teaching":[79],"learning.":[81]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-09-23T05:00:35.095934","created_date":"2022-07-25T00:00:00"}
