{"id":"https://openalex.org/W4286541709","doi":"https://doi.org/10.2139/ssrn.4161567","title":"Amyloid Conversion is Related to Risk Factors For Dementia","display_name":"Amyloid Conversion is Related to Risk Factors For Dementia","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4286541709","doi":"https://doi.org/10.2139/ssrn.4161567"},"language":"en","primary_location":{"id":"doi:10.2139/ssrn.4161567","doi":"https://doi.org/10.2139/ssrn.4161567","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4161567","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.2139/ssrn.4161567","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078501013","display_name":"Ren\u00e9e C. Groechel","orcid":"https://orcid.org/0000-0002-1771-5171","observed_orcids":["https://orcid.org/0000-0002-1771-5171"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Renee Groechel","raw_affiliation_strings":["Boston University School of Medicine"],"raw_orcid":"https://orcid.org/0000-0002-1771-5171","affiliations":[{"raw_affiliation_string":"Boston University School of Medicine","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088677579","display_name":"Yorghos Tripodis","orcid":"https://orcid.org/0000-0003-2190-7608","observed_orcids":["https://orcid.org/0000-0003-2190-7608"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yorghos Tripodis","raw_affiliation_strings":["Boston University - School of Public Health, Department of Biostatistics, 715 Albany Street, Boston, MA 02118, United States","Boston University - School of Public Health, Department of Biostatistics"],"raw_orcid":"https://orcid.org/0000-0003-2190-7608","affiliations":[{"raw_affiliation_string":"Boston University - School of Public Health, Department of Biostatistics, 715 Albany Street, Boston, MA 02118, United States","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Boston University - School of Public Health, Department of Biostatistics","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061694758","display_name":"Michael Louis Alosco","orcid":"https://orcid.org/0000-0002-8113-8428","observed_orcids":["https://orcid.org/0000-0002-8113-8428"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael  L. Alosco","raw_affiliation_strings":["Boston University - Alzheimer's Disease Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University - Alzheimer's Disease Center","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091558550","display_name":"Jesse B Mez","orcid":"https://orcid.org/0000-0003-1438-5442","observed_orcids":["https://orcid.org/0000-0003-1438-5442"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jesse Mez","raw_affiliation_strings":["Boston University - Alzheimer's Disease Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University - Alzheimer's Disease Center","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051442649","display_name":"Wei Qiao Qiu","orcid":"https://orcid.org/0000-0002-2082-2410","observed_orcids":["https://orcid.org/0000-0002-2082-2410"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei  Qiao Qiu","raw_affiliation_strings":["Boston University - Alzheimer's Disease Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University - Alzheimer's Disease Center","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028560837","display_name":"Gustavo Mercier","orcid":"https://orcid.org/0000-0002-9695-1550","observed_orcids":["https://orcid.org/0000-0002-9695-1550"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gustavo Mercier","raw_affiliation_strings":["Boston University - Alzheimer's Disease Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University - Alzheimer's Disease Center","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045045118","display_name":"Lee E. Goldstein","orcid":"https://orcid.org/0000-0001-8419-9800","observed_orcids":["https://orcid.org/0000-0001-8419-9800"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lee Goldstein","raw_affiliation_strings":["Boston University - Alzheimer's Disease Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University - Alzheimer's Disease Center","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037914760","display_name":"Andrew E. Budson","orcid":"https://orcid.org/0000-0002-2913-0015","observed_orcids":["https://orcid.org/0000-0002-2913-0015"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew  E. Budson","raw_affiliation_strings":["Boston University - Alzheimer's Disease Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University - Alzheimer's Disease Center","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022852165","display_name":"Neil W. Kowall","orcid":"https://orcid.org/0000-0002-6624-0213","observed_orcids":["https://orcid.org/0000-0002-6624-0213"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neil Kowall","raw_affiliation_strings":["Boston University - Alzheimer's Disease Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University - Alzheimer's Disease Center","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032770351","display_name":"Ronald Killiany","orcid":"https://orcid.org/0000-0003-4740-2181","observed_orcids":["https://orcid.org/0000-0003-4740-2181"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald  J. Killiany","raw_affiliation_strings":["Boston University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine","institution_ids":["https://openalex.org/I111088046"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5078501013"],"corresponding_institution_ids":["https://openalex.org/I111088046"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13077","display_name":"Cancer-related cognitive impairment studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyloid-beta","display_name":"amyloid-beta","score":0.7850000262260437},{"id":"https://openalex.org/keywords/risk-factors-for-dementia","display_name":"dementia risk factors","score":0.9210000038146973},{"id":"https://openalex.org/keywords/apoe-epsilon4","display_name":"APOE \u03b54","score":0.859000027179718},{"id":"https://openalex.org/keywords/florbetapir-pet","display_name":"florbetapir PET","score":0.9079999923706055},{"id":"https://openalex.org/keywords/brain-atrophy","display_name":"brain atrophy","score":0.828000009059906},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.6520000100135803},{"id":"https://openalex.org/keywords/preclinical-alzheimer-s-disease","display_name":"preclinical Alzheimer's disease","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.727729082107544},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.5037874579429626},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.37811461091041565},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3769572377204895},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.296317458152771},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23936620354652405},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.19228282570838928},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.15501248836517334}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2139/ssrn.4161567","doi":"https://doi.org/10.2139/ssrn.4161567","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4161567","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.2139/ssrn.4161567","doi":"https://doi.org/10.2139/ssrn.4161567","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4161567","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1906409993","https://openalex.org/W1963487177","https://openalex.org/W1993571512","https://openalex.org/W2008301592","https://openalex.org/W2010176747","https://openalex.org/W2070117026","https://openalex.org/W2078524519","https://openalex.org/W2083481304","https://openalex.org/W2084443965","https://openalex.org/W2101135654","https://openalex.org/W2103481737","https://openalex.org/W2103861278","https://openalex.org/W2105991991","https://openalex.org/W2110065044","https://openalex.org/W2132461552","https://openalex.org/W2133649359","https://openalex.org/W2139886607","https://openalex.org/W2147966319","https://openalex.org/W2329336071","https://openalex.org/W2528747982","https://openalex.org/W2530117917","https://openalex.org/W2766125374","https://openalex.org/W2788507110","https://openalex.org/W2792163733","https://openalex.org/W2798054687","https://openalex.org/W2887375324","https://openalex.org/W2897070036","https://openalex.org/W2910556588","https://openalex.org/W3014487247","https://openalex.org/W3099277996","https://openalex.org/W3111062478","https://openalex.org/W3127106548","https://openalex.org/W3132183957","https://openalex.org/W3157865811","https://openalex.org/W4210650500"],"related_works":["https://openalex.org/W4323655072","https://openalex.org/W4380893868","https://openalex.org/W4390200410","https://openalex.org/W4395683187","https://openalex.org/W7213381374","https://openalex.org/W4285094744","https://openalex.org/W4210543688","https://openalex.org/W4390199369","https://openalex.org/W4281401953","https://openalex.org/W4380883795"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-07-22T00:00:00"}