{"id":"https://openalex.org/W4285742130","doi":"https://doi.org/10.1371/journal.pone.0267566","title":"Detection of silent infection of severe acute respiratory syndrome coronavirus 2 by serological tests","display_name":"Detection of silent infection of severe acute respiratory syndrome coronavirus 2 by serological tests","publication_year":2022,"publication_date":"2022-05-20","ids":{"openalex":"https://openalex.org/W4285742130","doi":"https://doi.org/10.1371/journal.pone.0267566","pmid":"https://pubmed.ncbi.nlm.nih.gov/35594509","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9122508"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0267566","doi":"https://doi.org/10.1371/journal.pone.0267566","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0267566","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0267566&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0267566&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061549168","display_name":"Masashi Nishimura","orcid":"https://orcid.org/0000-0002-0654-7176","observed_orcids":["https://orcid.org/0000-0002-0654-7176"]},"institutions":[{"id":"https://openalex.org/I4210157830","display_name":"Tokyo Shinagawa Hospital","ror":"https://ror.org/05y7zcx10","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210157830"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masashi Nishimura","raw_affiliation_strings":["Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0002-0654-7176","affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210157830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069670977","display_name":"Satoshi Sugawa","orcid":"https://orcid.org/0000-0002-7988-4157","observed_orcids":["https://orcid.org/0000-0002-7988-4157"]},"institutions":[{"id":"https://openalex.org/I4210152531","display_name":"Abbott (Japan)","ror":"https://ror.org/04v748538","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210088555","https://openalex.org/I4210152531"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Satoshi Sugawa","raw_affiliation_strings":["Core Diagnostics, Abbott Japan LLC, Minato-Ku, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0002-7988-4157","affiliations":[{"raw_affiliation_string":"Core Diagnostics, Abbott Japan LLC, Minato-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210152531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020631090","display_name":"Shinichiro Ota","orcid":"https://orcid.org/0000-0002-0922-8656","observed_orcids":["https://orcid.org/0000-0002-0922-8656"]},"institutions":[{"id":"https://openalex.org/I119182057","display_name":"SHOWA Medical University","ror":"https://ror.org/04mzk4q39","country_code":"JP","type":"education","lineage":["https://openalex.org/I119182057"]},{"id":"https://openalex.org/I4210157830","display_name":"Tokyo Shinagawa Hospital","ror":"https://ror.org/05y7zcx10","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210157830"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichiro Ota","raw_affiliation_strings":["Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan","Department of physiology, Showa University School of Medicine, Shinagawa-Ku, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0002-0922-8656","affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210157830"]},{"raw_affiliation_string":"Department of physiology, Showa University School of Medicine, Shinagawa-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I119182057"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038266401","display_name":"Etsuko Suematsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157830","display_name":"Tokyo Shinagawa Hospital","ror":"https://ror.org/05y7zcx10","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210157830"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Etsuko Suematsu","raw_affiliation_strings":["Department of Clinical Laboratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Laboratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210157830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040492584","display_name":"Masahiro Shinoda","orcid":"https://orcid.org/0000-0002-0288-5637","observed_orcids":["https://orcid.org/0000-0002-0288-5637"]},"institutions":[{"id":"https://openalex.org/I4210157830","display_name":"Tokyo Shinagawa Hospital","ror":"https://ror.org/05y7zcx10","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210157830"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiro Shinoda","raw_affiliation_strings":["Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210157830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040053655","display_name":"Masaharu Shinkai","orcid":"https://orcid.org/0000-0002-4012-2518","observed_orcids":["https://orcid.org/0000-0002-4012-2518"]},"institutions":[{"id":"https://openalex.org/I4210157830","display_name":"Tokyo Shinagawa Hospital","ror":"https://ror.org/05y7zcx10","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210157830"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaharu Shinkai","raw_affiliation_strings":["Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4210157830"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5069670977"],"corresponding_institution_ids":["https://openalex.org/I4210152531"],"apc_list":{"value":1805,"currency":"USD","value_usd":1805},"apc_paid":{"value":1805,"currency":"USD","value_usd":1805},"fwci":0.7571,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.68425946,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"17","issue":"5","first_page":"e0267566","last_page":"e0267566"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.5365999937057495,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.5365999937057495,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.45170000195503235,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.9610000252723694},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9679999947547913},{"id":"https://openalex.org/keywords/silent-infection","display_name":"silent infection","score":0.9660000205039978},{"id":"https://openalex.org/keywords/serological-screening","display_name":"serological screening","score":0.574999988079071},{"id":"https://openalex.org/keywords/healthcare-workers","display_name":"healthcare workers","score":0.9319999814033508},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.8740000128746033},{"id":"https://openalex.org/keywords/sars-cov-2-seroprevalence","display_name":"SARS-CoV-2 seroprevalence","score":0.7459999918937683},{"id":"https://openalex.org/keywords/covid-19-wards","display_name":"COVID-19 wards","score":0.7129999995231628},{"id":"https://openalex.org/keywords/infection-surveillance","display_name":"infection surveillance","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6470534801483154},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.6362513303756714},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.5735276937484741},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.5119160413742065},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.4878070652484894},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.47376301884651184},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.46783721446990967},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4621826410293579},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.4605964422225952},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.34237825870513916},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32183143496513367},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.1147322952747345},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.09507063031196594}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000087124","descriptor_name":"COVID-19 Serological Testing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012698","descriptor_name":"Serologic Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058873","descriptor_name":"Pandemics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064370","descriptor_name":"Spike Glycoprotein, Coronavirus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1371/journal.pone.0267566","doi":"https://doi.org/10.1371/journal.pone.0267566","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0267566","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0267566&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmid:35594509","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35594509","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9122508","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9122508/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:4ce9a1311fd7468eba3b822c278ae278","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/4ce9a1311fd7468eba3b822c278ae278","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 17, Iss 5, p e0267566 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0267566","doi":"https://doi.org/10.1371/journal.pone.0267566","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0267566","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0267566&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310945","display_name":"Abbott Japan","ror":"https://ror.org/04v748538"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4285742130.pdf","grobid_xml":"https://content.openalex.org/works/W4285742130.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W3021039517","https://openalex.org/W3021238748","https://openalex.org/W3023609275","https://openalex.org/W3024006735","https://openalex.org/W3030605963","https://openalex.org/W3092136311","https://openalex.org/W3092890028","https://openalex.org/W3105273510","https://openalex.org/W3117382778","https://openalex.org/W3118409314","https://openalex.org/W3130250106","https://openalex.org/W3133926412","https://openalex.org/W3135254426","https://openalex.org/W3143959537","https://openalex.org/W3189544042","https://openalex.org/W3195763203","https://openalex.org/W3199326204","https://openalex.org/W3203930822","https://openalex.org/W4200443436","https://openalex.org/W6783892057"],"related_works":["https://openalex.org/W3203930822","https://openalex.org/W3123844745","https://openalex.org/W3047431327","https://openalex.org/W7128023350","https://openalex.org/W4307410308","https://openalex.org/W4223908428","https://openalex.org/W4386417727","https://openalex.org/W4387047243","https://openalex.org/W4389267619","https://openalex.org/W2045357369"],"abstract_inverted_index":{"BACKGROUND:":[0],"To":[1,14],"control":[2],"COVID-19":[3,54,142,200],"pandemic":[4],"is":[5,223],"of":[6,29,57,67,84,113,124,138,149,161,182,186,191,197,214,217,220,228,248],"critical":[7],"importance":[8],"to":[9,25,50,204,238],"the":[10,16,27,51,58,65,90,157,179,189,212,226,246,251,254,261,266],"global":[11],"public":[12],"health.":[13],"capture":[15],"prevalence":[17],"in":[18,141,152,199,236,250],"an":[19,242],"accurate":[20],"and":[21,24,118,133,166,174,195,207],"timely":[22],"manner":[23],"understand":[26],"mode":[28],"nosocomial":[30,215],"infection":[31,194,216,222],"are":[32],"essential":[33],"for":[34,64],"its":[35],"preventive":[36],"measure.":[37,244],"METHODS:":[38],"We":[39],"recruited":[40],"685":[41],"healthcare":[42],"workers":[43],"(HCW's)":[44],"at":[45],"Tokyo":[46],"Shinagawa":[47],"Hospital":[48],"prior":[49],"vaccination":[52],"with":[53,87,110,121,233],"vaccine.":[55],"Sera":[56],"subjects":[59],"were":[60,96,129,144,171,202],"tested":[61],"by":[62,93,104,155],"assays":[63],"titer":[66],"IgG":[68,78,106,108,119,162,164,167,187,234,257],"against":[69,79,169],"S":[70],"protein's":[71],"receptor":[72],"binding":[73],"domain":[74],"(IgG":[75,82,116,127],"(RBD))":[76],"or":[77],"nucleocapsid":[80],"protein":[81],"(N))":[83],"SARS-CoV-2.":[85],"Together":[86],"PCR":[88,170,183,239],"data,":[89],"positive":[91,100,180],"rates":[92,101,137,181],"these":[94],"methods":[95],"evaluated.":[97],"RESULTS:":[98],"Overall":[99],"among":[102,265],"HCW's":[103,139,150,198],"PCR,":[105],"(RBD),":[107,163,188],"(N)":[109,120],"a":[111,122],"cut-off":[112,123],"1.4":[114],"S/C":[115,126],"(N)1.4),":[117],"0.2":[125],"(N)0.2)":[128],"3.5%,":[130],"9.5%,":[131],"6.1%,":[132],"27.7%,":[134],"respectively.":[135,176,209],"Positive":[136],"working":[140,151],"ward":[143,154,201],"significantly":[145],"higher":[146],"than":[147],"those":[148],"non-COVID-19":[153],"all":[156],"four":[158],"methods.":[159],"Concordances":[160],"(N)1.4,":[165],"(N)0.2":[168,258],"97.1%,":[172],"71.4%,":[173],"88.6%,":[175],"By":[177],"subtracting":[178],"from":[184],"that":[185,196],"rate":[190],"overall":[192],"silent":[193,221],"estimated":[203],"be":[205,241,260],"6.0%":[206],"21.1%,":[208],"CONCLUSIONS:":[210],"For":[211,225,245],"prevention":[213],"SARS-CoV-2,":[218],"identification":[219],"essential.":[224],"detection":[227],"ongoing":[229],"infection,":[230],"periodical":[231],"screening":[232],"(RBD)":[235],"addition":[237],"would":[240],"effective":[243],"surveillance":[247],"morbidity":[249],"population,":[252],"on":[253],"other":[255],"hand,":[256],"could":[259],"most":[262],"reliable":[263],"indicator":[264],"three":[267],"serological":[268],"tests.":[269]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-07-18T00:00:00"}