{"id":"https://openalex.org/W4285741722","doi":null,"title":"QRISK3-based analysis of cardiovascular risk factors in patients with long-term but well-controlled systemic lupus erythematosus.","display_name":"QRISK3-based analysis of cardiovascular risk factors in patients with long-term but well-controlled systemic lupus erythematosus.","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4285741722","pmid":"https://pubmed.ncbi.nlm.nih.gov/35702101","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9185081"},"language":"en","primary_location":{"id":"pmid:35702101","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35702101","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9185081/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004313383","display_name":"Shuolin Wang","orcid":"https://orcid.org/0000-0001-8557-9186","observed_orcids":["https://orcid.org/0000-0001-8557-9186"]},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuo-Lin Wang","raw_affiliation_strings":["Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wei Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Li","raw_affiliation_strings":["Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054530372","display_name":"Tian-Fang Li","orcid":"https://orcid.org/0000-0002-3039-8676","observed_orcids":["https://orcid.org/0000-0002-3039-8676"]},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tian-Fang Li","raw_affiliation_strings":["Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101489913","display_name":"Liang Xu","orcid":"https://orcid.org/0000-0002-8865-7175","observed_orcids":["https://orcid.org/0000-0002-8865-7175"]},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xu Liang","raw_affiliation_strings":["Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101181420","display_name":"Ye-Lan Yan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ye-Lan Yan","raw_affiliation_strings":["Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020856857","display_name":"Shengyun Liu","orcid":"https://orcid.org/0000-0002-0426-1705","observed_orcids":["https://orcid.org/0000-0002-0426-1705"]},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sheng-Yun Liu","raw_affiliation_strings":["Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, First Affiliated Hospital of Zhengzhou University Zhengzhou, Henan, China","institution_ids":["https://openalex.org/I4210156804"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210156804"],"apc_list":null,"apc_paid":null,"fwci":0.306,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.49796513,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"14","issue":"5","first_page":"3247","last_page":"3260"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.828000009059906},{"id":"https://openalex.org/keywords/qrisk3","display_name":"QRISK3","score":0.9610000252723694},{"id":"https://openalex.org/keywords/resting-heart-rate","display_name":"resting heart rate","score":0.875},{"id":"https://openalex.org/keywords/lupus-nephritis","display_name":"lupus nephritis","score":0.8799999952316284},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/glucocorticoid-dose","display_name":"glucocorticoid dose","score":0.8209999799728394},{"id":"https://openalex.org/keywords/hydroxychloroquine","display_name":"hydroxychloroquine","score":0.9160000085830688},{"id":"https://openalex.org/keywords/mycophenolate-mofetil","display_name":"mycophenolate mofetil","score":0.9990000128746033},{"id":"https://openalex.org/keywords/age-of-onset","display_name":"age of onset","score":0.6850000023841858},{"id":"https://openalex.org/keywords/sledai-2k","display_name":"SLEDAI-2K","score":0.8790000081062317},{"id":"https://openalex.org/keywords/cardiovascular-risk-prediction","display_name":"cardiovascular risk prediction","score":0.6039999723434448},{"id":"https://openalex.org/keywords/aerobic-exercise","display_name":"aerobic exercise","score":0.6600000262260437}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9026514291763306},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6731886863708496},{"id":"https://openalex.org/C11783203","wikidata":"https://www.wikidata.org/wiki/Q5478027","display_name":"Framingham Risk Score","level":3,"score":0.6618857383728027},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6018660068511963},{"id":"https://openalex.org/C2775915377","wikidata":"https://www.wikidata.org/wiki/Q188297","display_name":"Lupus erythematosus","level":3,"score":0.4839206337928772},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.48095884919166565},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.43381866812705994},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2480219602584839},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmid:35702101","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35702101","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9185081","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9185081/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9185081","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9185081/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W1557753272","https://openalex.org/W1975307585","https://openalex.org/W1979095334","https://openalex.org/W1986349550","https://openalex.org/W1990938770","https://openalex.org/W2018088003","https://openalex.org/W2021741488","https://openalex.org/W2025292311","https://openalex.org/W2039093757","https://openalex.org/W2044410409","https://openalex.org/W2060449981","https://openalex.org/W2065219238","https://openalex.org/W2070527591","https://openalex.org/W2070811352","https://openalex.org/W2076688279","https://openalex.org/W2090170487","https://openalex.org/W2096657836","https://openalex.org/W2104572714","https://openalex.org/W2108905161","https://openalex.org/W2113642869","https://openalex.org/W2121586011","https://openalex.org/W2125448187","https://openalex.org/W2126478084","https://openalex.org/W2129448542","https://openalex.org/W2142043065","https://openalex.org/W2144590229","https://openalex.org/W2146203649","https://openalex.org/W2148092884","https://openalex.org/W2149113739","https://openalex.org/W2158214799","https://openalex.org/W2165779517","https://openalex.org/W2169221648","https://openalex.org/W2299474693","https://openalex.org/W2554537306","https://openalex.org/W2586057598","https://openalex.org/W2600285415","https://openalex.org/W2605678895","https://openalex.org/W2607031541","https://openalex.org/W2618596952","https://openalex.org/W2672904208","https://openalex.org/W2750879036","https://openalex.org/W2751703796","https://openalex.org/W2766783120","https://openalex.org/W2767264339","https://openalex.org/W2773434292","https://openalex.org/W2782286127","https://openalex.org/W2887558100","https://openalex.org/W2901241930","https://openalex.org/W2913879391","https://openalex.org/W2927871970","https://openalex.org/W2981191663","https://openalex.org/W2981871976","https://openalex.org/W2983699289","https://openalex.org/W2986295984","https://openalex.org/W2987944394","https://openalex.org/W2990198141","https://openalex.org/W2998884891","https://openalex.org/W3021030113","https://openalex.org/W3090003318","https://openalex.org/W3117105758","https://openalex.org/W4238251256"],"related_works":["https://openalex.org/W2887558100","https://openalex.org/W4399483791","https://openalex.org/W7133206164","https://openalex.org/W7133204942","https://openalex.org/W2938027789","https://openalex.org/W2014121321","https://openalex.org/W3164908522","https://openalex.org/W4213310094","https://openalex.org/W4415422989","https://openalex.org/W2551380155"],"abstract_inverted_index":{"=0.004).":[0],"Pearson's":[1],"correlation":[2,20],"showed":[3],"that":[4,54],"RHR":[5],"was":[6,56],"significantly":[7,104],"associated":[8,57],"with":[9,41,58],"aerobic":[10,29],"exercise":[11],"(r=-0.322,":[12],"p=0.001).":[13],"Subgroup":[14],"analysis":[15],"further":[16],"identified":[17],"a":[18,47,103],"positive":[19],"between":[21],"the":[22,36,90,127,134,147],"history":[23,63],"of":[24,33,38,51,64,82,93,108,122,136,150],"nephritis,":[25],"metabolic":[26,73],"syndrome":[27,74],"(MetS),":[28],"exercise,":[30],"present":[31],"dose":[32,92],"GCs,":[34],"and":[35,53,72,85,89,129,152],"RR":[37],"CVD.":[39],"Patients":[40],"long-term":[42,154],"but":[43],"well-controlled":[44],"SLE":[45,100,117,139],"had":[46,102],"high":[48,120],"relative":[49,106],"risk":[50,107,121,135],"CVD":[52,109,123,137],"this":[55],"resting":[59],"heart":[60],"rate":[61],"(P=0.003),":[62],"lupus":[65],"nephritis":[66],"(P<0.001),":[67,71,80],"initial":[68,91,148],"SLEDAI-2K":[69],"score":[70],"(P=0.017).":[75],"However,":[76],"age":[77],"at":[78,119],"onset":[79],"use":[81],"hydroxychloroquine":[83],"(P=0.30)":[84],"Mycophenolate":[86],"mofetil":[87],"(P=0.01),":[88],"glucocorticoid":[94],"(P=0.049),":[95],"were":[96],"protective":[97],"factors.":[98],"Younger":[99],"patients":[101,112,118],"higher":[105],"than":[110],"older":[111],"(p<0.001).":[113],"QRISK3":[114],"detected":[115],"more":[116],"when":[124],"compared":[125],"to":[126],"Framingham":[128],"recalibrate":[130],"SCORE.":[131],"To":[132],"reduce":[133],"in":[138],"patients,":[140],"measures":[141],"should":[142],"be":[143],"taken":[144],"both":[145],"during":[146],"stages":[149],"disease":[151],"for":[153],"management.":[155]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-07-18T00:00:00"}
