{"id":"https://openalex.org/W4285390937","doi":"https://doi.org/10.1186/s12979-022-00288-7","title":"Depression, aging, and immunity: implications for COVID-19 vaccine immunogenicity","display_name":"Depression, aging, and immunity: implications for COVID-19 vaccine immunogenicity","publication_year":2022,"publication_date":"2022-07-14","ids":{"openalex":"https://openalex.org/W4285390937","doi":"https://doi.org/10.1186/s12979-022-00288-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/35836263","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9281075"},"language":"en","primary_location":{"id":"doi:10.1186/s12979-022-00288-7","doi":"https://doi.org/10.1186/s12979-022-00288-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12979-022-00288-7","pdf_url":"https://immunityageing.biomedcentral.com/counter/pdf/10.1186/s12979-022-00288-7","source":{"id":"https://openalex.org/S183475463","display_name":"Immunity & Ageing","issn_l":"1742-4933","issn":["1742-4933"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity & Ageing","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://immunityageing.biomedcentral.com/counter/pdf/10.1186/s12979-022-00288-7","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010575489","display_name":"Bart N. Ford","orcid":"https://orcid.org/0000-0002-6269-0735","observed_orcids":["https://orcid.org/0000-0002-6269-0735"]},"institutions":[{"id":"https://openalex.org/I74022624","display_name":"Oklahoma State University Center for Health Sciences","ror":"https://ror.org/02mfxdp77","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I74022624"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bart N. Ford","raw_affiliation_strings":["Department of Pharmacology & Physiology, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology & Physiology, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA","institution_ids":["https://openalex.org/I74022624"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033435451","display_name":"Jonathan B. Savitz","orcid":"https://orcid.org/0000-0001-8143-182X","observed_orcids":["https://orcid.org/0000-0001-8143-182X"]},"institutions":[{"id":"https://openalex.org/I4210159521","display_name":"Laureate Institute for Brain Research","ror":"https://ror.org/05e6pjy56","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210159521"]},{"id":"https://openalex.org/I87208437","display_name":"University of Tulsa","ror":"https://ror.org/04wn28048","country_code":"US","type":"education","lineage":["https://openalex.org/I87208437"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jonathan Savitz","raw_affiliation_strings":["Laureate Institute for Brain Research, Tulsa, OK, USA. jsavitz@laureateinstitute.org","Oxley College of Health Sciences, The University of Tulsa, Tulsa, OK, USA. jsavitz@laureateinstitute.org","Laureate Institute for Brain Research, Tulsa, OK, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laureate Institute for Brain Research, Tulsa, OK, USA. jsavitz@laureateinstitute.org","institution_ids":["https://openalex.org/I4210159521"]},{"raw_affiliation_string":"Oxley College of Health Sciences, The University of Tulsa, Tulsa, OK, USA. jsavitz@laureateinstitute.org","institution_ids":["https://openalex.org/I87208437"]},{"raw_affiliation_string":"Laureate Institute for Brain Research, Tulsa, OK, USA","institution_ids":["https://openalex.org/I4210159521"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5033435451"],"corresponding_institution_ids":["https://openalex.org/I4210159521","https://openalex.org/I87208437"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":0.6494,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.58283019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"19","issue":"1","first_page":"32","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.5282999873161316,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.5282999873161316,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.17659999430179596,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10168","display_name":"COVID-19 and Mental Health","score":0.14920000731945038,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.7429999709129333},{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.8700000047683716},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.5529999732971191},{"id":"https://openalex.org/keywords/covid-19-vaccine-immunogenicity","display_name":"COVID-19 vaccine immunogenicity","score":0.8199999928474426},{"id":"https://openalex.org/keywords/accelerated-biological-aging","display_name":"accelerated biological aging","score":0.7699999809265137},{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.8190000057220459},{"id":"https://openalex.org/keywords/vaccine-prioritization","display_name":"vaccine prioritization","score":0.652999997138977},{"id":"https://openalex.org/keywords/immune-response-to-infection","display_name":"immune response to infection","score":0.5950000286102295}],"concepts":[{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.7434836626052856},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.6878689527511597},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6744563579559326},{"id":"https://openalex.org/C2779056147","wikidata":"https://www.wikidata.org/wiki/Q1660191","display_name":"Immunosenescence","level":3,"score":0.5887852311134338},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5331465601921082},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5306538343429565},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.49792003631591797},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4890185296535492},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.4671076536178589},{"id":"https://openalex.org/C89623803","wikidata":"https://www.wikidata.org/wiki/Q12184","display_name":"Pandemic","level":5,"score":0.4657825827598572},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.46118882298469543},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.44372519850730896},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.4334607720375061},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.32186204195022583},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.24828922748565674},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11727127432823181},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10601884126663208},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.10315844416618347},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/s12979-022-00288-7","doi":"https://doi.org/10.1186/s12979-022-00288-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12979-022-00288-7","pdf_url":"https://immunityageing.biomedcentral.com/counter/pdf/10.1186/s12979-022-00288-7","source":{"id":"https://openalex.org/S183475463","display_name":"Immunity & Ageing","issn_l":"1742-4933","issn":["1742-4933"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity & Ageing","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9281075","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9281075","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immun Ageing","raw_type":"Text"},{"id":"pmid:35836263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35836263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity & ageing : I & A","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:9ba305e9ec8640a197035eb1308c7022","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/9ba305e9ec8640a197035eb1308c7022","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Immunity & Ageing, Vol 19, Iss 1, Pp 1-14 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12979-022-00288-7","doi":"https://doi.org/10.1186/s12979-022-00288-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12979-022-00288-7","pdf_url":"https://immunityageing.biomedcentral.com/counter/pdf/10.1186/s12979-022-00288-7","source":{"id":"https://openalex.org/S183475463","display_name":"Immunity & Ageing","issn_l":"1742-4933","issn":["1742-4933"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity & Ageing","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1024701614","display_name":null,"funder_award_id":"P20GM121312","funder_id":"https://openalex.org/F4320306544","funder_display_name":"William K. Warren Foundation"},{"id":"https://openalex.org/G9000874747","display_name":"Neural response to inflammatory challenge in major depressive disorder","funder_award_id":"R01MH123652","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000890374","display_name":"The Center for Neuroscience-based Mental Health Assessment and Prediction (NeuroMAP)","funder_award_id":"P20GM121312","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306147","display_name":"Brain and Behavior Research Foundation","ror":"https://ror.org/03a63f080"},{"id":"https://openalex.org/F4320306544","display_name":"William K. Warren Foundation","ror":"https://ror.org/0174xkn11"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4285390937.pdf","grobid_xml":"https://content.openalex.org/works/W4285390937.grobid-xml"},"referenced_works_count":179,"referenced_works":["https://openalex.org/W54691793","https://openalex.org/W138925795","https://openalex.org/W1503928854","https://openalex.org/W1508177354","https://openalex.org/W1512778167","https://openalex.org/W1538295107","https://openalex.org/W1577134145","https://openalex.org/W1733523167","https://openalex.org/W1920486352","https://openalex.org/W1969425174","https://openalex.org/W1969485091","https://openalex.org/W1974262825","https://openalex.org/W1982795254","https://openalex.org/W1983426396","https://openalex.org/W1985380081","https://openalex.org/W1988338839","https://openalex.org/W1992455678","https://openalex.org/W1992470868","https://openalex.org/W2001720505","https://openalex.org/W2023003954","https://openalex.org/W2027992900","https://openalex.org/W2030396834","https://openalex.org/W2033028677","https://openalex.org/W2034630933","https://openalex.org/W2034750640","https://openalex.org/W2049419835","https://openalex.org/W2052444641","https://openalex.org/W2077402716","https://openalex.org/W2080808232","https://openalex.org/W2081789109","https://openalex.org/W2085734226","https://openalex.org/W2088868199","https://openalex.org/W2089244708","https://openalex.org/W2097572674","https://openalex.org/W2097663158","https://openalex.org/W2111742578","https://openalex.org/W2116205810","https://openalex.org/W2117554687","https://openalex.org/W2118424059","https://openalex.org/W2122510079","https://openalex.org/W2127064468","https://openalex.org/W2129270330","https://openalex.org/W2129904810","https://openalex.org/W2136342964","https://openalex.org/W2139841187","https://openalex.org/W2140497145","https://openalex.org/W2149150642","https://openalex.org/W2149984789","https://openalex.org/W2152386281","https://openalex.org/W2152541965","https://openalex.org/W2153840275","https://openalex.org/W2157203934","https://openalex.org/W2168805652","https://openalex.org/W2188949284","https://openalex.org/W2189028582","https://openalex.org/W2201607793","https://openalex.org/W2229921221","https://openalex.org/W2315258249","https://openalex.org/W2327530675","https://openalex.org/W2467613733","https://openalex.org/W2479582436","https://openalex.org/W2531162495","https://openalex.org/W2532576306","https://openalex.org/W2562506237","https://openalex.org/W2601743864","https://openalex.org/W2755084841","https://openalex.org/W2767478650","https://openalex.org/W2786714211","https://openalex.org/W2792066582","https://openalex.org/W2843990653","https://openalex.org/W2885738092","https://openalex.org/W2887700639","https://openalex.org/W2889094070","https://openalex.org/W2912654909","https://openalex.org/W2915157760","https://openalex.org/W2919967752","https://openalex.org/W2924236163","https://openalex.org/W2929049496","https://openalex.org/W2960982983","https://openalex.org/W2969767589","https://openalex.org/W2981907242","https://openalex.org/W2993908729","https://openalex.org/W3003646454","https://openalex.org/W3007037952","https://openalex.org/W3011187754","https://openalex.org/W3014493418","https://openalex.org/W3015126610","https://openalex.org/W3024838586","https://openalex.org/W3027649310","https://openalex.org/W3036386821","https://openalex.org/W3036649375","https://openalex.org/W3040050420","https://openalex.org/W3075884737","https://openalex.org/W3086642606","https://openalex.org/W3088489318","https://openalex.org/W3090717270","https://openalex.org/W3091369593","https://openalex.org/W3108660532","https://openalex.org/W3109751641","https://openalex.org/W3111255098","https://openalex.org/W3112500788","https://openalex.org/W3113734454","https://openalex.org/W3120808506","https://openalex.org/W3124814292","https://openalex.org/W3127565366","https://openalex.org/W3128853581","https://openalex.org/W3130206057","https://openalex.org/W3130903241","https://openalex.org/W3134061302","https://openalex.org/W3134189953","https://openalex.org/W3137307037","https://openalex.org/W3139173191","https://openalex.org/W3142193311","https://openalex.org/W3145686672","https://openalex.org/W3146579363","https://openalex.org/W3148333766","https://openalex.org/W3150786652","https://openalex.org/W3153040293","https://openalex.org/W3153508314","https://openalex.org/W3154170850","https://openalex.org/W3154431393","https://openalex.org/W3154739456","https://openalex.org/W3155040466","https://openalex.org/W3155756133","https://openalex.org/W3156866359","https://openalex.org/W3158103490","https://openalex.org/W3158247426","https://openalex.org/W3158750369","https://openalex.org/W3160932186","https://openalex.org/W3161308067","https://openalex.org/W3166460483","https://openalex.org/W3167280716","https://openalex.org/W3167899147","https://openalex.org/W3168042374","https://openalex.org/W3172450091","https://openalex.org/W3174017401","https://openalex.org/W3176479223","https://openalex.org/W3176552995","https://openalex.org/W3176897911","https://openalex.org/W3177007930","https://openalex.org/W3184107630","https://openalex.org/W3184437506","https://openalex.org/W3186181241","https://openalex.org/W3186279334","https://openalex.org/W3186677792","https://openalex.org/W3189544042","https://openalex.org/W3189865447","https://openalex.org/W3193744815","https://openalex.org/W3197137678","https://openalex.org/W3198831432","https://openalex.org/W3199670916","https://openalex.org/W3199923482","https://openalex.org/W3200303519","https://openalex.org/W3202234535","https://openalex.org/W3205258492","https://openalex.org/W3206807960","https://openalex.org/W3209349647","https://openalex.org/W3209683048","https://openalex.org/W3212999615","https://openalex.org/W3214313466","https://openalex.org/W3215030919","https://openalex.org/W3216957364","https://openalex.org/W3217005852","https://openalex.org/W3217731723","https://openalex.org/W4205172639","https://openalex.org/W4205354784","https://openalex.org/W4205483821","https://openalex.org/W4205527954","https://openalex.org/W4205708037","https://openalex.org/W4210317504","https://openalex.org/W4210350488","https://openalex.org/W4210493562","https://openalex.org/W4211043735","https://openalex.org/W4212880839","https://openalex.org/W4213167748","https://openalex.org/W4223919269","https://openalex.org/W4225544422","https://openalex.org/W4226377601","https://openalex.org/W4281557772"],"related_works":["https://openalex.org/W3188024186","https://openalex.org/W81816560","https://openalex.org/W4210791565","https://openalex.org/W4413765628","https://openalex.org/W4405964707","https://openalex.org/W3204636643","https://openalex.org/W3047050326","https://openalex.org/W4390083739","https://openalex.org/W4362716793","https://openalex.org/W3194656598"],"abstract_inverted_index":{"The":[0],"aging":[1],"process":[2],"can":[3],"have":[4],"detrimental":[5],"effects":[6],"on":[7],"the":[8,12,40,72,75,81],"immune":[9,56],"system":[10],"rendering":[11],"elderly":[13,50],"more":[14],"susceptible":[15],"to":[16,22,31,54,58],"infectious":[17],"disease":[18],"and":[19,60,100],"less":[20],"responsive":[21],"vaccination.":[23,61],"Major":[24],"depressive":[25],"disorder":[26],"(MDD)":[27],"has":[28],"been":[29],"hypothesized":[30],"show":[32,46],"characteristics":[33],"of":[34,68,74],"accelerated":[35],"biological":[36],"aging.":[37],"This":[38],"raises":[39],"possibility":[41],"that":[42,87,108,121],"depressed":[43],"individuals":[44],"will":[45],"some":[47],"overlap":[48],"with":[49,52,127],"populations":[51,120],"respect":[53],"their":[55],"response":[57],"infection":[59,99],"Here":[62],"we":[63],"provide":[64],"an":[65],"umbrella":[66],"review":[67],"this":[69],"literature":[70],"in":[71],"context":[73],"SARS":[76],"CoV-2":[77],"pandemic.":[78],"On":[79],"balance,":[80],"available":[82],"data":[83],"do":[84],"indeed":[85],"suggest":[86],"depression":[88],"is":[89],"a":[90],"risk":[91],"factor":[92],"for":[93,101,124],"both":[94],"adverse":[95],"outcomes":[96],"following":[97],"COVID-19":[98,103],"reduced":[102],"vaccine":[104],"immunogenicity.":[105],"We":[106],"conclude":[107],"MDD":[109],"(and":[110],"other":[111,128],"major":[112],"psychiatric":[113],"disorders)":[114],"should":[115],"be":[116],"recognized":[117],"as":[118],"vulnerable":[119],"receive":[122],"priority":[123],"vaccination":[125],"along":[126],"at-risk":[129],"groups.":[130]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-07-14T00:00:00"}