{"id":"https://openalex.org/W4285108989","doi":"https://doi.org/10.2139/ssrn.4111684","title":"Gaba and Inhibitory Physiology in Dominant Motor Cortex: Altered Moderation of Response Inhibition in Children with ADHD","display_name":"Gaba and Inhibitory Physiology in Dominant Motor Cortex: Altered Moderation of Response Inhibition in Children with ADHD","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4285108989","doi":"https://doi.org/10.2139/ssrn.4111684"},"language":"en","primary_location":{"id":"doi:10.2139/ssrn.4111684","doi":"https://doi.org/10.2139/ssrn.4111684","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4111684","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.2139/ssrn.4111684","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005424070","display_name":"Donald L. Gilbert","orcid":"https://orcid.org/0000-0002-9245-6878","observed_orcids":["https://orcid.org/0000-0002-9245-6878"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Donald L. Gilbert","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078260471","display_name":"Joshua B. Ewen","orcid":"https://orcid.org/0000-0002-9203-9564","observed_orcids":["https://orcid.org/0000-0002-9203-9564"]},"institutions":[{"id":"https://openalex.org/I1298154867","display_name":"Kennedy Krieger Institute","ror":"https://ror.org/05q6tgt32","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1298154867"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua B. Ewen","raw_affiliation_strings":["Johns Hopkins University - Kennedy Krieger Institute, Baltimore, MD 21205, United States","Johns Hopkins University - Kennedy Krieger Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University - Kennedy Krieger Institute, Baltimore, MD 21205, United States","institution_ids":["https://openalex.org/I1298154867","https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins University - Kennedy Krieger Institute","institution_ids":["https://openalex.org/I1298154867","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046525385","display_name":"David A. Huddleston","orcid":"https://orcid.org/0000-0001-5950-2062","observed_orcids":["https://orcid.org/0000-0001-5950-2062"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David A. Huddleston","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052731444","display_name":"Steve W. Wu","orcid":"https://orcid.org/0000-0001-5102-174X","observed_orcids":["https://orcid.org/0000-0001-5102-174X"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steve W. Wu","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017607647","display_name":"Kim M. Cecil","orcid":"https://orcid.org/0000-0001-8233-5485","observed_orcids":["https://orcid.org/0000-0001-8233-5485"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim M. Cecil","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040347516","display_name":"Richard A.E. Edden","orcid":"https://orcid.org/0000-0002-0671-7374","observed_orcids":["https://orcid.org/0000-0002-0671-7374"]},"institutions":[{"id":"https://openalex.org/I1298154867","display_name":"Kennedy Krieger Institute","ror":"https://ror.org/05q6tgt32","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1298154867"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Edden","raw_affiliation_strings":["Johns Hopkins University - Kennedy Krieger Institute, Baltimore, MD 21205, United States","Johns Hopkins University - Kennedy Krieger Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University - Kennedy Krieger Institute, Baltimore, MD 21205, United States","institution_ids":["https://openalex.org/I1298154867","https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins University - Kennedy Krieger Institute","institution_ids":["https://openalex.org/I1298154867","https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021838784","display_name":"Travis R. Larsh","orcid":"https://orcid.org/0000-0001-6214-2731","observed_orcids":["https://orcid.org/0000-0001-6214-2731"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Travis Larsh","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008823765","display_name":"Paul S. Horn","orcid":"https://orcid.org/0000-0002-4990-5754","observed_orcids":["https://orcid.org/0000-0002-4990-5754"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul S. Horn","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center, Department of Pediatrics, Division of Neurology","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025684368","display_name":"Deana Crocetti","orcid":"https://orcid.org/0000-0001-8311-4107","observed_orcids":["https://orcid.org/0000-0001-8311-4107"]},"institutions":[{"id":"https://openalex.org/I1298154867","display_name":"Kennedy Krieger Institute","ror":"https://ror.org/05q6tgt32","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1298154867"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deana Crocetti","raw_affiliation_strings":["Johns Hopkins University - Kennedy Krieger Institute, Baltimore, MD 21205, United States","Johns Hopkins University - Kennedy Krieger Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University - Kennedy Krieger Institute, Baltimore, MD 21205, United States","institution_ids":["https://openalex.org/I1298154867","https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins University - Kennedy Krieger Institute","institution_ids":["https://openalex.org/I1298154867","https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025787531","display_name":"Stewart H. Mostofsky","orcid":"https://orcid.org/0000-0002-8515-2411","observed_orcids":["https://orcid.org/0000-0002-8515-2411"]},"institutions":[{"id":"https://openalex.org/I1298154867","display_name":"Kennedy Krieger Institute","ror":"https://ror.org/05q6tgt32","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1298154867"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stewart Mostofsky","raw_affiliation_strings":["Johns Hopkins University - Kennedy Krieger Institute, Baltimore, MD 21205, United States","Johns Hopkins University - Kennedy Krieger Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University - Kennedy Krieger Institute, Baltimore, MD 21205, United States","institution_ids":["https://openalex.org/I1298154867","https://openalex.org/I145311948"]},{"raw_affiliation_string":"Johns Hopkins University - Kennedy Krieger Institute","institution_ids":["https://openalex.org/I1298154867","https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005424070"],"corresponding_institution_ids":["https://openalex.org/I1285204247"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.9380000233650208},{"id":"https://openalex.org/keywords/response-inhibition","display_name":"response inhibition","score":0.9929999709129333},{"id":"https://openalex.org/keywords/motor-cortex","display_name":"motor cortex","score":0.6349999904632568},{"id":"https://openalex.org/keywords/gaba","display_name":"GABA","score":0.6859999895095825},{"id":"https://openalex.org/keywords/cortical-silent-period","display_name":"cortical silent period","score":0.7379999756813049},{"id":"https://openalex.org/keywords/stop-signal-reaction-time","display_name":"stop-signal reaction time","score":0.8460000157356262},{"id":"https://openalex.org/keywords/cognitive-control","display_name":"cognitive control","score":0.8259999752044678},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.7789999842643738}],"concepts":[{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.8050801157951355},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7017533779144287},{"id":"https://openalex.org/C2992805700","wikidata":"https://www.wikidata.org/wiki/Q6033829","display_name":"Response inhibition","level":3,"score":0.6322067975997925},{"id":"https://openalex.org/C93225998","wikidata":"https://www.wikidata.org/wiki/Q1941972","display_name":"Moderation","level":2,"score":0.6180111765861511},{"id":"https://openalex.org/C2778796910","wikidata":"https://www.wikidata.org/wiki/Q6033829","display_name":"Inhibitory control","level":3,"score":0.5769600868225098},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.57021164894104},{"id":"https://openalex.org/C2778373776","wikidata":"https://www.wikidata.org/wiki/Q18696","display_name":"Motor cortex","level":3,"score":0.5222131013870239},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.2686511278152466},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.10711812973022461},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.08751395344734192}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2139/ssrn.4111684","doi":"https://doi.org/10.2139/ssrn.4111684","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4111684","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2139/ssrn.4111684","doi":"https://doi.org/10.2139/ssrn.4111684","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4111684","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1901260206","https://openalex.org/W1957708244","https://openalex.org/W1961049053","https://openalex.org/W1966724464","https://openalex.org/W1968429176","https://openalex.org/W1981243489","https://openalex.org/W1982378812","https://openalex.org/W1992297809","https://openalex.org/W2001357677","https://openalex.org/W2036630871","https://openalex.org/W2038027593","https://openalex.org/W2059651555","https://openalex.org/W2066872782","https://openalex.org/W2080624766","https://openalex.org/W2089776745","https://openalex.org/W2093209361","https://openalex.org/W2095122838","https://openalex.org/W2096729555","https://openalex.org/W2133705337","https://openalex.org/W2144379775","https://openalex.org/W2146140292","https://openalex.org/W2158282570","https://openalex.org/W2585397751","https://openalex.org/W2731491280","https://openalex.org/W2782404141","https://openalex.org/W2786712756","https://openalex.org/W2789999049","https://openalex.org/W2887909021","https://openalex.org/W2905117398","https://openalex.org/W2957561527","https://openalex.org/W3040212938","https://openalex.org/W3093743108","https://openalex.org/W3097041920","https://openalex.org/W3138384121","https://openalex.org/W3159710762","https://openalex.org/W3166385405","https://openalex.org/W3216125577","https://openalex.org/W4200040812","https://openalex.org/W4224212725"],"related_works":["https://openalex.org/W3138384121","https://openalex.org/W4406395541","https://openalex.org/W2957561527","https://openalex.org/W2912031650","https://openalex.org/W2133705337","https://openalex.org/W2066872782","https://openalex.org/W2130853179","https://openalex.org/W2594453081","https://openalex.org/W4389412189","https://openalex.org/W4284880688"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-07-14T00:00:00"}