{"id":"https://openalex.org/W4285079377","doi":"https://doi.org/10.1007/978-1-0716-2237-7_15","title":"Identification and Validation of Candidate Genes from Genome-Wide Association Studies","display_name":"Identification and Validation of Candidate Genes from Genome-Wide Association Studies","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4285079377","doi":"https://doi.org/10.1007/978-1-0716-2237-7_15","pmid":"https://pubmed.ncbi.nlm.nih.gov/35641769"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-0716-2237-7_15","doi":"https://doi.org/10.1007/978-1-0716-2237-7_15","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-0716-2237-7_15","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W3161754487","display_name":"Genome-Wide Association Studies"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003417544","display_name":"Elise Albert","orcid":"https://orcid.org/0000-0001-5060-4505","observed_orcids":["https://orcid.org/0000-0001-5060-4505"]},"institutions":[{"id":"https://openalex.org/I4387155952","display_name":"Syngenta (France)","ror":"https://ror.org/0310sdb05","country_code":"FR","type":"company","lineage":["https://openalex.org/I4387155952","https://openalex.org/I89199228"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Elise Albert","raw_affiliation_strings":["Syngenta SAS France, Saint Sauveur, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Syngenta SAS France, Saint Sauveur, France","institution_ids":["https://openalex.org/I4387155952"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085176423","display_name":"Christopher Sauvage","orcid":"https://orcid.org/0000-0001-5466-9955","observed_orcids":["https://orcid.org/0000-0001-5466-9955"]},"institutions":[{"id":"https://openalex.org/I4387155952","display_name":"Syngenta (France)","ror":"https://ror.org/0310sdb05","country_code":"FR","type":"company","lineage":["https://openalex.org/I4387155952","https://openalex.org/I89199228"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christopher Sauvage","raw_affiliation_strings":["Syngenta SAS France, Saint Sauveur, France. christopher.sauvage.1@gmail.com","Syngenta SAS France, Saint Sauveur, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Syngenta SAS France, Saint Sauveur, France. christopher.sauvage.1@gmail.com","institution_ids":["https://openalex.org/I4387155952"]},{"raw_affiliation_string":"Syngenta SAS France, Saint Sauveur, France","institution_ids":["https://openalex.org/I4387155952"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4387155952"],"apc_list":null,"apc_paid":null,"fwci":2.2712,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.8738414,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"2481","issue":null,"first_page":"249","last_page":"272"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9086999893188477,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9086999893188477,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.05490000173449516,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.017999999225139618,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/candidate-gene-identification","display_name":"candidate gene identification","score":0.9100000262260437},{"id":"https://openalex.org/keywords/candidate-gene-validation","display_name":"candidate gene validation","score":0.847000002861023},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"genome-wide association study","score":0.8069999814033508},{"id":"https://openalex.org/keywords/meta-gwas","display_name":"meta-GWAS","score":0.7789999842643738},{"id":"https://openalex.org/keywords/fine-mapping","display_name":"fine mapping","score":0.8610000014305115},{"id":"https://openalex.org/keywords/variant-prioritization","display_name":"variant prioritization","score":0.8709999918937683},{"id":"https://openalex.org/keywords/plant-breeding","display_name":"plant breeding","score":0.718999981880188},{"id":"https://openalex.org/keywords/plant-genetics","display_name":"plant genetics","score":0.3310000002384186}],"concepts":[{"id":"https://openalex.org/C69991583","wikidata":"https://www.wikidata.org/wiki/Q1423575","display_name":"Candidate gene","level":3,"score":0.8426051139831543},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.8201364278793335},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.7423638701438904},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.6266727447509766},{"id":"https://openalex.org/C2777615720","wikidata":"https://www.wikidata.org/wiki/Q11888847","display_name":"Prioritization","level":2,"score":0.5542214512825012},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5343735814094543},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.5157309174537659},{"id":"https://openalex.org/C9287583","wikidata":"https://www.wikidata.org/wiki/Q5532883","display_name":"Genetic architecture","level":4,"score":0.5109068751335144},{"id":"https://openalex.org/C106934330","wikidata":"https://www.wikidata.org/wiki/Q1971873","display_name":"Trait","level":2,"score":0.46554550528526306},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4453912377357483},{"id":"https://openalex.org/C21249469","wikidata":"https://www.wikidata.org/wiki/Q5433313","display_name":"Family-based QTL mapping","level":5,"score":0.4379446506500244},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32437729835510254},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3079524040222168},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3025558888912201},{"id":"https://openalex.org/C122735190","wikidata":"https://www.wikidata.org/wiki/Q715789","display_name":"Gene mapping","level":4,"score":0.2373603880405426},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.17133033275604248},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11101588606834412},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.057792335748672485},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.0},{"id":"https://openalex.org/C539667460","wikidata":"https://www.wikidata.org/wiki/Q2414942","display_name":"Management science","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069600","descriptor_name":"Plant Breeding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-0716-2237-7_15","doi":"https://doi.org/10.1007/978-1-0716-2237-7_15","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-0716-2237-7_15","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology","raw_type":"book-chapter"},{"id":"pmid:35641769","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35641769","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in molecular biology (Clifton, N.J.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1968886567","https://openalex.org/W1973413549","https://openalex.org/W1974964336","https://openalex.org/W1986911601","https://openalex.org/W1988591324","https://openalex.org/W1992436001","https://openalex.org/W2019983262","https://openalex.org/W2024108088","https://openalex.org/W2032230252","https://openalex.org/W2039153962","https://openalex.org/W2042421957","https://openalex.org/W2048069305","https://openalex.org/W2048352123","https://openalex.org/W2078059415","https://openalex.org/W2080228983","https://openalex.org/W2086493366","https://openalex.org/W2089839075","https://openalex.org/W2106779017","https://openalex.org/W2119067354","https://openalex.org/W2127922938","https://openalex.org/W2132981035","https://openalex.org/W2133301154","https://openalex.org/W2133520037","https://openalex.org/W2137797806","https://openalex.org/W2138345444","https://openalex.org/W2139852278","https://openalex.org/W2146374090","https://openalex.org/W2161620511","https://openalex.org/W2163013660","https://openalex.org/W2236822143","https://openalex.org/W2419574648","https://openalex.org/W2553123256","https://openalex.org/W2561769852","https://openalex.org/W2766730353","https://openalex.org/W2783749221","https://openalex.org/W2792335017","https://openalex.org/W2806225217","https://openalex.org/W2905051475","https://openalex.org/W2927655628","https://openalex.org/W2934861239","https://openalex.org/W2943309532","https://openalex.org/W2953159153","https://openalex.org/W2962812015","https://openalex.org/W2964434160","https://openalex.org/W3025060722","https://openalex.org/W3042068575","https://openalex.org/W3139318029","https://openalex.org/W3150284325","https://openalex.org/W3154390514","https://openalex.org/W4300196896"],"related_works":["https://openalex.org/W2999009832","https://openalex.org/W2767785164","https://openalex.org/W2806225217","https://openalex.org/W3203277023","https://openalex.org/W2794019424","https://openalex.org/W2051616601","https://openalex.org/W4396829599","https://openalex.org/W7167708793","https://openalex.org/W7098198219","https://openalex.org/W4323543690"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-07-13T00:00:00"}