{"id":"https://openalex.org/W4285077205","doi":"https://doi.org/10.1089/thy.2021.0656","title":"Impact of Thyroid Autoimmunity on Assisted Reproductive Technology Outcomes and Ovarian Reserve Markers: An Updated Systematic Review and Meta-Analysis","display_name":"Impact of Thyroid Autoimmunity on Assisted Reproductive Technology Outcomes and Ovarian Reserve Markers: An Updated Systematic Review and Meta-Analysis","publication_year":2022,"publication_date":"2022-07-12","ids":{"openalex":"https://openalex.org/W4285077205","doi":"https://doi.org/10.1089/thy.2021.0656","pmid":"https://pubmed.ncbi.nlm.nih.gov/35819278"},"language":"en","primary_location":{"id":"doi:10.1089/thy.2021.0656","doi":"https://doi.org/10.1089/thy.2021.0656","is_oa":false,"landing_page_url":"https://doi.org/10.1089/thy.2021.0656","pdf_url":null,"source":{"id":"https://openalex.org/S27569427","display_name":"Thyroid","issn_l":"1050-7256","issn":["1050-7256","1557-9077"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thyroid\u00ae","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036017087","display_name":"Andrea Busnelli","orcid":"https://orcid.org/0000-0001-9870-5241","observed_orcids":["https://orcid.org/0000-0001-9870-5241"]},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Andrea Busnelli","raw_affiliation_strings":["Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy","Division of Gynecology and Reproductive Medicine, Department of Gynecology, IRCCS Humanitas Research Hospital, Fertility Center, Rozzano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy","institution_ids":["https://openalex.org/I1339471597"]},{"raw_affiliation_string":"Division of Gynecology and Reproductive Medicine, Department of Gynecology, IRCCS Humanitas Research Hospital, Fertility Center, Rozzano, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056311668","display_name":"Carola Beltratti","orcid":"https://orcid.org/0009-0000-4263-822X","observed_orcids":["https://orcid.org/0009-0000-4263-822X"]},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carola Beltratti","raw_affiliation_strings":["Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy","institution_ids":["https://openalex.org/I1339471597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017271360","display_name":"Federico Cirillo","orcid":"https://orcid.org/0000-0003-4695-1621","observed_orcids":["https://orcid.org/0000-0003-4695-1621"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federico Cirillo","raw_affiliation_strings":["Division of Gynecology and Reproductive Medicine, Department of Gynecology, IRCCS Humanitas Research Hospital, Fertility Center, Rozzano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gynecology and Reproductive Medicine, Department of Gynecology, IRCCS Humanitas Research Hospital, Fertility Center, Rozzano, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110607610","display_name":"Alessandro Bulfoni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alessandro Bulfoni","raw_affiliation_strings":["Division of Obstetrics and Gynecology, Humanitas S. Pio X Hospital, Rozzano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Obstetrics and Gynecology, Humanitas S. Pio X Hospital, Rozzano, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011245991","display_name":"Andrea Gerardo Lania","orcid":"https://orcid.org/0000-0002-5380-2141","observed_orcids":["https://orcid.org/0000-0002-5380-2141"]},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Lania","raw_affiliation_strings":["Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy","Endocrinology, Diabetology and Medical Andrology Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy","institution_ids":["https://openalex.org/I1339471597"]},{"raw_affiliation_string":"Endocrinology, Diabetology and Medical Andrology Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037954837","display_name":"Paolo Emanuele Levi-Setti","orcid":"https://orcid.org/0000-0003-1024-4386","observed_orcids":["https://orcid.org/0000-0003-1024-4386"]},"institutions":[{"id":"https://openalex.org/I1339471597","display_name":"Humanitas University","ror":"https://ror.org/020dggs04","country_code":"IT","type":"education","lineage":["https://openalex.org/I1339471597"]},{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Emanuele Levi-Setti","raw_affiliation_strings":["Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy","Division of Gynecology and Reproductive Medicine, Department of Gynecology, IRCCS Humanitas Research Hospital, Fertility Center, Rozzano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy","institution_ids":["https://openalex.org/I1339471597"]},{"raw_affiliation_string":"Division of Gynecology and Reproductive Medicine, Department of Gynecology, IRCCS Humanitas Research Hospital, Fertility Center, Rozzano, Italy","institution_ids":["https://openalex.org/I4210163047"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5036017087"],"corresponding_institution_ids":["https://openalex.org/I1339471597","https://openalex.org/I4210163047"],"apc_list":null,"apc_paid":null,"fwci":0.7463,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.66401062,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"32","issue":"9","first_page":"1010","last_page":"1028"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.8101000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.8101000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.06379999965429306,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.03849999979138374,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thyroid-autoimmunity","display_name":"thyroid autoimmunity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/assisted-reproductive-technology-outcomes","display_name":"assisted reproduction outcomes","score":0.953000009059906},{"id":"https://openalex.org/keywords/ovarian-reserve","display_name":"ovarian reserve","score":0.9509999752044678},{"id":"https://openalex.org/keywords/miscarriage","display_name":"miscarriage","score":0.7229999899864197},{"id":"https://openalex.org/keywords/embryo-implantation","display_name":"embryo implantation","score":0.9240000247955322},{"id":"https://openalex.org/keywords/live-birth-rate","display_name":"live birth rate","score":0.9539999961853027},{"id":"https://openalex.org/keywords/anti-mullerian-hormone","display_name":"anti-M\u00fcllerian hormone","score":0.8500000238418579},{"id":"https://openalex.org/keywords/antral-follicle-count","display_name":"antral follicle count","score":0.8930000066757202},{"id":"https://openalex.org/keywords/follicle-stimulating-hormone","display_name":"follicle-stimulating hormone","score":0.8460000157356262},{"id":"https://openalex.org/keywords/intracytoplasmic-sperm-injection","display_name":"intracytoplasmic sperm injection","score":0.9409999847412109},{"id":"https://openalex.org/keywords/female-fertility","display_name":"female fertility","score":0.6399999856948853},{"id":"https://openalex.org/keywords/oocyte-quantity","display_name":"oocyte quantity","score":0.492000013589859},{"id":"https://openalex.org/keywords/oocyte-retrieval-number","display_name":"oocyte retrieval number","score":0.47099998593330383},{"id":"https://openalex.org/keywords/fertilization-rate","display_name":"fertilization rate","score":0.8320000171661377},{"id":"https://openalex.org/keywords/clinical-pregnancy-rate","display_name":"clinical pregnancy rate","score":0.9769999980926514}],"concepts":[{"id":"https://openalex.org/C2776600139","wikidata":"https://www.wikidata.org/wiki/Q7113253","display_name":"Ovarian reserve","level":4,"score":0.8549903631210327},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.766194224357605},{"id":"https://openalex.org/C2779245376","wikidata":"https://www.wikidata.org/wiki/Q28693","display_name":"Miscarriage","level":3,"score":0.7137436866760254},{"id":"https://openalex.org/C2778279030","wikidata":"https://www.wikidata.org/wiki/Q1543380","display_name":"Live birth","level":3,"score":0.6913978457450867},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.5786767601966858},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5595857501029968},{"id":"https://openalex.org/C500014431","wikidata":"https://www.wikidata.org/wiki/Q25862","display_name":"Assisted reproductive technology","level":4,"score":0.5467268228530884},{"id":"https://openalex.org/C142773365","wikidata":"https://www.wikidata.org/wiki/Q3499793","display_name":"Antral follicle","level":3,"score":0.5352808833122253},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4894463121891022},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.48045843839645386},{"id":"https://openalex.org/C2778780466","wikidata":"https://www.wikidata.org/wiki/Q21108939","display_name":"Anti-M\u00fcllerian hormone","level":3,"score":0.47602608799934387},{"id":"https://openalex.org/C187960798","wikidata":"https://www.wikidata.org/wiki/Q7631152","display_name":"Subgroup analysis","level":3,"score":0.4720633327960968},{"id":"https://openalex.org/C2776537878","wikidata":"https://www.wikidata.org/wiki/Q7239894","display_name":"Pregnancy rate","level":3,"score":0.4675862789154053},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4594498574733734},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.42809680104255676},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3752098083496094},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3267810344696045},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.23874858021736145},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09923222661018372},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000022","descriptor_name":"Abortion, Spontaneous","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005640","descriptor_name":"Follicle Stimulating Hormone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015551","descriptor_name":"Autoimmunity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018873","descriptor_name":"Pregnancy Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027724","descriptor_name":"Reproductive Techniques, Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D050498","descriptor_name":"Live Birth","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D054304","descriptor_name":"Anti-Mullerian Hormone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065851","descriptor_name":"Ovarian Reserve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1089/thy.2021.0656","doi":"https://doi.org/10.1089/thy.2021.0656","is_oa":false,"landing_page_url":"https://doi.org/10.1089/thy.2021.0656","pdf_url":null,"source":{"id":"https://openalex.org/S27569427","display_name":"Thyroid","issn_l":"1050-7256","issn":["1050-7256","1557-9077"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thyroid\u00ae","raw_type":"journal-article"},{"id":"pmid:35819278","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35819278","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thyroid : official journal of the American Thyroid Association","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":81,"referenced_works":["https://openalex.org/W1563077783","https://openalex.org/W1599710237","https://openalex.org/W1728966119","https://openalex.org/W1766575968","https://openalex.org/W1927362421","https://openalex.org/W1950401811","https://openalex.org/W1968135325","https://openalex.org/W1972774449","https://openalex.org/W1973061504","https://openalex.org/W1979423827","https://openalex.org/W1992128077","https://openalex.org/W1999151418","https://openalex.org/W2020378875","https://openalex.org/W2026126246","https://openalex.org/W2031919315","https://openalex.org/W2051197268","https://openalex.org/W2058245650","https://openalex.org/W2058820400","https://openalex.org/W2066672702","https://openalex.org/W2079039990","https://openalex.org/W2086123357","https://openalex.org/W2097222243","https://openalex.org/W2104349009","https://openalex.org/W2116892060","https://openalex.org/W2117311316","https://openalex.org/W2123725842","https://openalex.org/W2128474430","https://openalex.org/W2128739796","https://openalex.org/W2130635109","https://openalex.org/W2135400982","https://openalex.org/W2136619105","https://openalex.org/W2137130997","https://openalex.org/W2153143103","https://openalex.org/W2154521309","https://openalex.org/W2161426907","https://openalex.org/W2169545598","https://openalex.org/W2177163953","https://openalex.org/W2309700868","https://openalex.org/W2472457845","https://openalex.org/W2590423505","https://openalex.org/W2739504526","https://openalex.org/W2742707863","https://openalex.org/W2747389129","https://openalex.org/W2765471614","https://openalex.org/W2767931869","https://openalex.org/W2775428017","https://openalex.org/W2789591406","https://openalex.org/W2794993113","https://openalex.org/W2803850065","https://openalex.org/W2809698214","https://openalex.org/W2838759849","https://openalex.org/W2887293167","https://openalex.org/W2888657807","https://openalex.org/W2913390101","https://openalex.org/W2913799187","https://openalex.org/W2947589405","https://openalex.org/W2965686865","https://openalex.org/W2974601104","https://openalex.org/W2981878147","https://openalex.org/W2998623041","https://openalex.org/W3000203893","https://openalex.org/W3003422246","https://openalex.org/W3024591798","https://openalex.org/W3032010460","https://openalex.org/W3045632928","https://openalex.org/W3091964076","https://openalex.org/W3094121074","https://openalex.org/W3107475537","https://openalex.org/W3108367424","https://openalex.org/W3119045782","https://openalex.org/W3119429199","https://openalex.org/W3123732187","https://openalex.org/W3123893780","https://openalex.org/W3125936179","https://openalex.org/W3138666970","https://openalex.org/W3139649361","https://openalex.org/W3153137120","https://openalex.org/W3158128449","https://openalex.org/W3178173521","https://openalex.org/W3203396968","https://openalex.org/W4200442773"],"related_works":["https://openalex.org/W4415992782","https://openalex.org/W4412758379","https://openalex.org/W2472457845","https://openalex.org/W4410325634","https://openalex.org/W7072421070","https://openalex.org/W3000203893","https://openalex.org/W2343775247","https://openalex.org/W3108367424","https://openalex.org/W4281738837","https://openalex.org/W2789591406"],"abstract_inverted_index":{"Background:":[0],"Thyroid":[1],"autoimmunity":[2],"(TAI)":[3],"has":[4],"a":[5,126,145,171,234,274],"high":[6],"prevalence":[7],"among":[8],"women":[9,114,282],"of":[10,24,29,40,63,94,109,147,166,174,195,237,256,259,277,289,299,307,314],"reproductive":[11,45],"age.":[12],"Investigating":[13],"its":[14],"possible":[15,311],"impact":[16],"on":[17,42],"ovarian":[18,50,95],"function":[19],"and":[20,33,49,56,88,107,134,158,211,248,302],"fertility":[21],"is,":[22],"thus,":[23],"utmost":[25],"relevance.":[26],"The":[27,164,246,310],"aim":[28],"this":[30],"systematic":[31,54,127],"review":[32,55],"meta-analysis":[34,57],"was":[35,58,168],"to":[36,60,139,264],"elucidate":[37],"the":[38,67,253,287,295,300,308],"effect":[39,313],"TAI":[41,70,167],"both":[43],"assisted":[44],"technology":[46],"(ART)":[47],"outcomes":[48,75,280],"reserve.":[51],"Methods:":[52],"This":[53,270],"restricted":[59],"two":[61],"groups":[62],"research":[64],"articles":[65],"investigating":[66],"association":[68],"between":[69],"and:":[71],"(1)":[72],"autologous":[73],"ART":[74,279],"(i.e.,":[76,97],"fertilization":[77],"rate":[78,84],"[FR],":[79],"implantation":[80,197],"rate,":[81,87],"clinical":[82,325],"pregnancy":[83],"[CPR],":[85],"miscarriage":[86,175],"live":[89,212],"birth":[90,213],"rate),":[91],"(2)":[92],"markers":[93,258],"reserve":[96],"anti-M\u00fcllerian":[98],"hormone,":[99,103],"basal":[100],"follicle":[101,105],"stimulating":[102],"antral":[104],"count,":[106],"number":[108],"oocytes":[110],"retrieved).":[111],"Studies":[112],"including":[113],"affected":[115,266],"by":[116,125,267,294],"overt":[117],"hypo/hyperthyroidism":[118],"were":[119,123,153,229],"excluded.":[120],"Relevant":[121],"studies":[122,152,160],"identified":[124,149],"search":[128],"in":[129,155,161,233,281,305,322],"PubMed,":[130],"MEDLINE,":[131],"ClinicalTrials.gov,":[132],"Embase,":[133],"Scopus,":[135],"from":[136],"database":[137],"inception":[138],"May":[140],"1,":[141],"2022.":[142],"Results:":[143],"From":[144],"total":[146],"432":[148],"publications,":[150],"22":[151],"included":[154],"Group":[156,162],"1":[157],"26":[159],"2.":[163],"presence":[165],"associated":[169],"with":[170,283],"higher":[172,275],"risk":[173,276],"(7606":[176],"participants,":[177,199,215],"odds":[178],"ratio":[179],"[OR]":[180],"1.52,":[181],"confidence":[182],"interval":[183],"[CI":[184,202,218],"1.14\u20132.01],":[185],"p":[186,204,220],"=":[187,191,205,209,221,225],"0.004,":[188],"I":[189,207,223],"2":[190,208,224],"53%),":[192],"lower":[193],"chance":[194],"embryo":[196],"(7118":[198],"OR":[200,216],"0.72,":[201],"0.59\u20130.88],":[203],"0.001,":[206],"36%),":[210],"(11417":[214],"0.73,":[217],"0.56\u20130.94],":[219],"0.02,":[222],"71%).":[226],"These":[227],"associations":[228],"no":[230],"longer":[231],"observed":[232],"subgroup":[235],"analysis":[236],"patients":[238],"who":[239],"exclusively":[240],"underwent":[241],"intracytoplasmic":[242],"sperm":[243],"injection":[244],"(ICSI).":[245],"FR":[247],"CPR":[249],"as":[250,252],"well":[251],"mean":[254],"values":[255],"surrogate":[257],"oocyte":[260],"quantity":[261],"appeared":[262],"not":[263],"be":[265,320],"TAI.":[268,285],"Conclusions:":[269],"data":[271],"synthesis":[272],"suggest":[273],"adverse":[278],"positive":[284],"However,":[286],"reliability":[288],"these":[290],"findings":[291],"is":[292,316],"hampered":[293],"relatively":[296],"low":[297],"quality":[298],"evidence":[301],"significant":[303],"heterogeneity":[304],"many":[306],"meta-analyses.":[309],"protective":[312],"ICSI":[315],"promising":[317],"but":[318],"should":[319],"confirmed":[321],"controlled":[323],"prospective":[324],"trials.":[326],"PROSPERO":[327],"Registration":[328],"ID":[329],":":[330],"CRD42021236529.":[331]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-07-13T00:00:00"}
