{"id":"https://openalex.org/W4285034796","doi":"https://doi.org/10.7150/ijms.71840","title":"Advances in Circular RNA and Its Applications","display_name":"Advances in Circular RNA and Its Applications","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4285034796","doi":"https://doi.org/10.7150/ijms.71840","pmid":"https://pubmed.ncbi.nlm.nih.gov/35813288","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9254372"},"language":"en","primary_location":{"id":"doi:10.7150/ijms.71840","doi":"https://doi.org/10.7150/ijms.71840","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.71840","pdf_url":"https://www.medsci.org/v19p0975.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.medsci.org/v19p0975.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102012227","display_name":"Xian Zhao","orcid":"https://orcid.org/0000-0002-7789-2700","observed_orcids":["https://orcid.org/0000-0002-7789-2700"]},"institutions":[{"id":"https://openalex.org/I4210108242","display_name":"National Vaccine and Serum Institute","ror":"https://ror.org/01p5m7v59","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210108242"]},{"id":"https://openalex.org/I4210113926","display_name":"China National Biotechnology (China)","ror":"https://ror.org/01y20q665","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210113926"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xian Zhao","raw_affiliation_strings":["National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China","institution_ids":["https://openalex.org/I4210108242","https://openalex.org/I4210113926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112844982","display_name":"Youxiu Zhong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108242","display_name":"National Vaccine and Serum Institute","ror":"https://ror.org/01p5m7v59","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210108242"]},{"id":"https://openalex.org/I4210113926","display_name":"China National Biotechnology (China)","ror":"https://ror.org/01y20q665","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210113926"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Youxiu Zhong","raw_affiliation_strings":["National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China","institution_ids":["https://openalex.org/I4210108242","https://openalex.org/I4210113926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100348152","display_name":"Xudong Wang","orcid":"https://orcid.org/0000-0002-9686-2072","observed_orcids":["https://orcid.org/0000-0002-9686-2072"]},"institutions":[{"id":"https://openalex.org/I4210108242","display_name":"National Vaccine and Serum Institute","ror":"https://ror.org/01p5m7v59","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210108242"]},{"id":"https://openalex.org/I4210113926","display_name":"China National Biotechnology (China)","ror":"https://ror.org/01y20q665","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210113926"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xudong Wang","raw_affiliation_strings":["National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China","institution_ids":["https://openalex.org/I4210108242","https://openalex.org/I4210113926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044150795","display_name":"Jiuheng Shen","orcid":"https://orcid.org/0009-0003-9350-3300","observed_orcids":["https://orcid.org/0009-0003-9350-3300"]},"institutions":[{"id":"https://openalex.org/I4210108242","display_name":"National Vaccine and Serum Institute","ror":"https://ror.org/01p5m7v59","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210108242"]},{"id":"https://openalex.org/I4210113926","display_name":"China National Biotechnology (China)","ror":"https://ror.org/01y20q665","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210113926"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiuheng Shen","raw_affiliation_strings":["National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China","institution_ids":["https://openalex.org/I4210108242","https://openalex.org/I4210113926"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5114025775","display_name":"Wenlin An","orcid":"https://orcid.org/0000-0002-0180-7282","observed_orcids":["https://orcid.org/0000-0002-0180-7282","https://orcid.org/0000-0002-6634-3466"]},"institutions":[{"id":"https://openalex.org/I4210108242","display_name":"National Vaccine and Serum Institute","ror":"https://ror.org/01p5m7v59","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210108242"]},{"id":"https://openalex.org/I4210113926","display_name":"China National Biotechnology (China)","ror":"https://ror.org/01y20q665","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210113926"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenlin An","raw_affiliation_strings":["National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Vaccine & Serum Institute (NVSI), China National Biotech Group (CNBG), No. 38 Jing Hai Second Road, Beijing, 101111, China","institution_ids":["https://openalex.org/I4210108242","https://openalex.org/I4210113926"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5114025775"],"corresponding_institution_ids":["https://openalex.org/I4210108242","https://openalex.org/I4210113926"],"apc_list":{"value":2000,"currency":"AUD","value_usd":1337},"apc_paid":{"value":2000,"currency":"AUD","value_usd":1337},"fwci":4.3159,"has_fulltext":true,"cited_by_count":220,"citation_normalized_percentile":{"value":0.97141861,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"19","issue":"6","first_page":"975","last_page":"985"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circular-rna","display_name":"circular RNA","score":1.0},{"id":"https://openalex.org/keywords/non-coding-rna","display_name":"non-coding RNA","score":0.9309999942779541},{"id":"https://openalex.org/keywords/circrna-biogenesis","display_name":"circRNA biogenesis","score":0.7839999794960022},{"id":"https://openalex.org/keywords/circrna-mirna-interaction","display_name":"circRNA-miRNA interaction","score":0.9190000295639038},{"id":"https://openalex.org/keywords/microrna-sponging","display_name":"microRNA sponging","score":0.8090000152587891},{"id":"https://openalex.org/keywords/rna-stability","display_name":"RNA stability","score":0.5230000019073486},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C2775893923","wikidata":"https://www.wikidata.org/wiki/Q17113455","display_name":"Circular RNA","level":4,"score":0.8335345983505249},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.7065472602844238},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6512666940689087},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6493593454360962},{"id":"https://openalex.org/C194993378","wikidata":"https://www.wikidata.org/wiki/Q427087","display_name":"Non-coding RNA","level":4,"score":0.6435701847076416},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5901641845703125},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.47474485635757446},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.4685811698436737},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4634281396865845},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29862338304519653}],"mesh":[{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.7150/ijms.71840","doi":"https://doi.org/10.7150/ijms.71840","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.71840","pdf_url":"https://www.medsci.org/v19p0975.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},{"id":"pmid:35813288","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35813288","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of medical sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9254372","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9254372/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Med Sci","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7150/ijms.71840","doi":"https://doi.org/10.7150/ijms.71840","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.71840","pdf_url":"https://www.medsci.org/v19p0975.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4285034796.pdf","grobid_xml":"https://content.openalex.org/works/W4285034796.grobid-xml"},"referenced_works_count":111,"referenced_works":["https://openalex.org/W7669837","https://openalex.org/W1521279639","https://openalex.org/W1915536483","https://openalex.org/W1966411071","https://openalex.org/W1966557314","https://openalex.org/W1981726010","https://openalex.org/W1981913677","https://openalex.org/W2004572268","https://openalex.org/W2005993715","https://openalex.org/W2008976996","https://openalex.org/W2018127856","https://openalex.org/W2019230794","https://openalex.org/W2021054898","https://openalex.org/W2031593782","https://openalex.org/W2034305079","https://openalex.org/W2050108172","https://openalex.org/W2054891772","https://openalex.org/W2055493067","https://openalex.org/W2058835062","https://openalex.org/W2059646461","https://openalex.org/W2062984171","https://openalex.org/W2064165694","https://openalex.org/W2066747004","https://openalex.org/W2100155969","https://openalex.org/W2115221577","https://openalex.org/W2115662330","https://openalex.org/W2116445148","https://openalex.org/W2128549339","https://openalex.org/W2142330662","https://openalex.org/W2142739728","https://openalex.org/W2147806662","https://openalex.org/W2149574104","https://openalex.org/W2155366992","https://openalex.org/W2168031418","https://openalex.org/W2178935826","https://openalex.org/W2210577735","https://openalex.org/W2281134225","https://openalex.org/W2290820108","https://openalex.org/W2302185643","https://openalex.org/W2464424326","https://openalex.org/W2507445921","https://openalex.org/W2530008209","https://openalex.org/W2557141539","https://openalex.org/W2572160591","https://openalex.org/W2582971078","https://openalex.org/W2592988313","https://openalex.org/W2597894202","https://openalex.org/W2600581473","https://openalex.org/W2601436215","https://openalex.org/W2624817122","https://openalex.org/W2624872288","https://openalex.org/W2735787554","https://openalex.org/W2751617348","https://openalex.org/W2754041968","https://openalex.org/W2759279048","https://openalex.org/W2782708334","https://openalex.org/W2785637603","https://openalex.org/W2800488651","https://openalex.org/W2800766678","https://openalex.org/W2883062882","https://openalex.org/W2885493792","https://openalex.org/W2892630678","https://openalex.org/W2899291183","https://openalex.org/W2921554472","https://openalex.org/W2925033480","https://openalex.org/W2936259264","https://openalex.org/W2941873727","https://openalex.org/W2942409680","https://openalex.org/W2945567360","https://openalex.org/W2967043226","https://openalex.org/W2968060972","https://openalex.org/W2979506092","https://openalex.org/W2998701262","https://openalex.org/W3002821084","https://openalex.org/W3003217347","https://openalex.org/W3004280078","https://openalex.org/W3013613552","https://openalex.org/W3017559929","https://openalex.org/W3020855961","https://openalex.org/W3021447865","https://openalex.org/W3027073936","https://openalex.org/W3043722389","https://openalex.org/W3043991892","https://openalex.org/W3045596302","https://openalex.org/W3046061621","https://openalex.org/W3046633757","https://openalex.org/W3047091198","https://openalex.org/W3047437072","https://openalex.org/W3090844627","https://openalex.org/W3093353093","https://openalex.org/W3093367571","https://openalex.org/W3095653445","https://openalex.org/W3109746568","https://openalex.org/W3115710812","https://openalex.org/W3122875512","https://openalex.org/W3123551159","https://openalex.org/W3135170287","https://openalex.org/W3157913957","https://openalex.org/W3160668788","https://openalex.org/W3168787503","https://openalex.org/W3174449879","https://openalex.org/W3201334827","https://openalex.org/W3208652861","https://openalex.org/W3216065158","https://openalex.org/W3217355073","https://openalex.org/W4200567023","https://openalex.org/W4226027283","https://openalex.org/W4237600298","https://openalex.org/W4246400823","https://openalex.org/W4319432157","https://openalex.org/W6781173592"],"related_works":["https://openalex.org/W3169402619","https://openalex.org/W3029248382","https://openalex.org/W7155268669","https://openalex.org/W4405597386","https://openalex.org/W2892630678","https://openalex.org/W2791173369","https://openalex.org/W3032470871","https://openalex.org/W4403185692","https://openalex.org/W3180519258","https://openalex.org/W2972168835"],"abstract_inverted_index":{"Circular":[0],"RNA":[1,8,18,40],"(circRNA)":[2],"is":[3,14,37,48],"a":[4,15,33],"novel":[5],"endogenous":[6],"non-coding":[7],"(ncRNA)":[9],"that,":[10],"like":[11],"microRNA":[12],"(miRNA),":[13],"rapidly":[16],"emerging":[17],"research":[19],"topic.":[20],"CircRNA,":[21],"unlike":[22],"traditional":[23],"linear":[24],"RNAs":[25],"(which":[26],"have":[27,55],"5'":[28],"and":[29,47,82,96,116,125],"3'":[30],"ends),":[31],"has":[32,44],"closed-loop":[34],"structure":[35],"that":[36],"unaffected":[38],"by":[39],"exonucleases.":[41],"Thus,":[42],"circRNA":[43],"sustained":[45],"expression":[46,115],"less":[49],"sensitive":[50],"to":[51],"degradation.":[52],"Since":[53],"circRNAs":[54,99,105],"many":[56],"miRNAs":[57],"binding":[58],"sites,":[59],"eliminating":[60],"their":[61,65,71],"repressive":[62],"effects":[63],"on":[64],"target":[66],"genes":[67],"can":[68,106],"strongly":[69],"enhance":[70],"expression.":[72],"CircRNAs":[73],"serve":[74],"an":[75],"important":[76],"regulatory":[77],"role":[78],"in":[79,93,100],"disease":[80],"onset":[81],"progression":[83],"via":[84],"specific":[85],"circRNA-miRNA":[86],"interactions.":[87],"We":[88],"summarized":[89],"the":[90,122,129],"current":[91],"progress":[92],"elucidating":[94],"mechanisms":[95],"biogenesis":[97],"of":[98,131],"this":[101],"review.":[102],"In":[103],"particular,":[104],"function":[107],"mainly":[108],"as":[109],"miRNA":[110],"sponges,":[111],"regulating":[112],"host":[113],"gene":[114],"protein":[117],"transportation.":[118],"Finally,":[119],"we":[120],"discussed":[121],"application":[123],"prospects":[124],"significant":[126],"challenges":[127],"for":[128],"development":[130],"circRNA-based":[132],"therapeutics.":[133]},"counts_by_year":[{"year":2026,"cited_by_count":49},{"year":2025,"cited_by_count":67},{"year":2024,"cited_by_count":72},{"year":2023,"cited_by_count":25},{"year":2022,"cited_by_count":7}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2022-07-12T00:00:00"}