{"id":"https://openalex.org/W4283796972","doi":"https://doi.org/10.2174/1568026622666220701091339","title":"Machine Learning and Artificial Intelligence: A Paradigm Shift in Big Data-Driven Drug Design and Discovery","display_name":"Machine Learning and Artificial Intelligence: A Paradigm Shift in Big Data-Driven Drug Design and Discovery","publication_year":2022,"publication_date":"2022-07-04","ids":{"openalex":"https://openalex.org/W4283796972","doi":"https://doi.org/10.2174/1568026622666220701091339","pmid":"https://pubmed.ncbi.nlm.nih.gov/35786336"},"language":"en","primary_location":{"id":"doi:10.2174/1568026622666220701091339","doi":"https://doi.org/10.2174/1568026622666220701091339","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1568026622666220701091339","pdf_url":null,"source":{"id":"https://openalex.org/S107732428","display_name":"Current Topics in Medicinal Chemistry","issn_l":"1568-0266","issn":["1568-0266","1873-4294"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Medicinal Chemistry","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084449361","display_name":"Purvashi Pasrija","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110166357","display_name":"University of Delhi","ror":"https://ror.org/04gzb2213","country_code":"IN","type":"education","lineage":["https://openalex.org/I110166357"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Purvashi Pasrija","raw_affiliation_strings":["Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India","institution_ids":["https://openalex.org/I110166357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078461257","display_name":"Prakash K. Jha","orcid":"https://orcid.org/0000-0001-8951-1875","observed_orcids":["https://orcid.org/0000-0001-8951-1875"]},"institutions":[{"id":"https://openalex.org/I110166357","display_name":"University of Delhi","ror":"https://ror.org/04gzb2213","country_code":"IN","type":"education","lineage":["https://openalex.org/I110166357"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Prakash Jha","raw_affiliation_strings":["Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India","institution_ids":["https://openalex.org/I110166357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051157198","display_name":"Pruthvi Upadhyaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110166357","display_name":"University of Delhi","ror":"https://ror.org/04gzb2213","country_code":"IN","type":"education","lineage":["https://openalex.org/I110166357"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pruthvi Upadhyaya","raw_affiliation_strings":["Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India","institution_ids":["https://openalex.org/I110166357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051622108","display_name":"Mohd Shoaib Khan","orcid":"https://orcid.org/0000-0002-2822-7608","observed_orcids":["https://orcid.org/0000-0002-2822-7608"]},"institutions":[{"id":"https://openalex.org/I110166357","display_name":"University of Delhi","ror":"https://ror.org/04gzb2213","country_code":"IN","type":"education","lineage":["https://openalex.org/I110166357"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Mohd. Shoaib Khan","raw_affiliation_strings":["Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India","institution_ids":["https://openalex.org/I110166357"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008128993","display_name":"Madhu Chopra","orcid":"https://orcid.org/0000-0003-3154-7335","observed_orcids":["https://orcid.org/0000-0003-3154-7335"]},"institutions":[{"id":"https://openalex.org/I110166357","display_name":"University of Delhi","ror":"https://ror.org/04gzb2213","country_code":"IN","type":"education","lineage":["https://openalex.org/I110166357"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Madhu Chopra","raw_affiliation_strings":["Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India","Laboratory of Molecular Modeling and Anticancer Drug Development, Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Infrastructure Facility (BIF), Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India","institution_ids":["https://openalex.org/I110166357"]},{"raw_affiliation_string":"Laboratory of Molecular Modeling and Anticancer Drug Development, Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, 110007, India","institution_ids":["https://openalex.org/I110166357"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5008128993","https://openalex.org/A5051622108"],"corresponding_institution_ids":["https://openalex.org/I110166357"],"apc_list":null,"apc_paid":null,"fwci":1.3211,"has_fulltext":false,"cited_by_count":84,"citation_normalized_percentile":{"value":0.82058047,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"22","issue":"20","first_page":"1692","last_page":"1727"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11948","display_name":"Machine Learning in Materials Science","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence-in-drug-discovery","display_name":"artificial intelligence in drug discovery","score":0.9639999866485596},{"id":"https://openalex.org/keywords/machine-learning","display_name":"machine learning","score":0.718999981880188},{"id":"https://openalex.org/keywords/deep-learning","display_name":"deep learning","score":0.9900000095367432},{"id":"https://openalex.org/keywords/big-data","display_name":"big data","score":0.8309999704360962},{"id":"https://openalex.org/keywords/drug-design","display_name":"drug design","score":0.9459999799728394},{"id":"https://openalex.org/keywords/drug-development-timelines","display_name":"drug development timelines","score":0.7789999842643738},{"id":"https://openalex.org/keywords/model-evaluation-metrics","display_name":"model evaluation metrics","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7739711999893188},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7501159310340881},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.6331294178962708},{"id":"https://openalex.org/C4438859","wikidata":"https://www.wikidata.org/wiki/Q186117","display_name":"Timeline","level":2,"score":0.632725715637207},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.6278926134109497},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5998086333274841},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.5661876797676086},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5008120536804199},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.4281724691390991},{"id":"https://openalex.org/C120567893","wikidata":"https://www.wikidata.org/wiki/Q1582085","display_name":"Knowledge extraction","level":2,"score":0.41604506969451904},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4064424932003021},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.21987783908843994},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1481589674949646},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077558","descriptor_name":"Big Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2174/1568026622666220701091339","doi":"https://doi.org/10.2174/1568026622666220701091339","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1568026622666220701091339","pdf_url":null,"source":{"id":"https://openalex.org/S107732428","display_name":"Current Topics in Medicinal Chemistry","issn_l":"1568-0266","issn":["1568-0266","1873-4294"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Medicinal Chemistry","raw_type":"journal-article"},{"id":"pmid:35786336","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35786336","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current topics in medicinal chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1720023422","display_name":null,"funder_award_id":"BT/PR40153/BTIS/137/8/2021","funder_id":"https://openalex.org/F4320320717","funder_display_name":"Department of Biotechnology, Ministry of Science and Technology, India"},{"id":"https://openalex.org/G5150906725","display_name":null,"funder_award_id":"DST/INSPIRE/03/2016/000026","funder_id":"https://openalex.org/F4320320719","funder_display_name":"Department of Science and Technology, Ministry of Science and Technology, India"}],"funders":[{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"},{"id":"https://openalex.org/F4320320719","display_name":"Department of Science and Technology, Ministry of Science and Technology, India","ror":"https://ror.org/0101xrq71"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":373,"referenced_works":["https://openalex.org/W13034104","https://openalex.org/W14024944","https://openalex.org/W21669203","https://openalex.org/W213139077","https://openalex.org/W658643376","https://openalex.org/W1031578623","https://openalex.org/W1500036797","https://openalex.org/W1559711086","https://openalex.org/W1582926274","https://openalex.org/W1653739410","https://openalex.org/W1791437014","https://openalex.org/W1896494894","https://openalex.org/W1965607248","https://openalex.org/W1966708530","https://openalex.org/W1967742674","https://openalex.org/W1968966573","https://openalex.org/W1971223189","https://openalex.org/W1971375063","https://openalex.org/W1972752819","https://openalex.org/W1974166884","https://openalex.org/W1975623001","https://openalex.org/W1975875826","https://openalex.org/W1976874178","https://openalex.org/W1977629193","https://openalex.org/W1978733464","https://openalex.org/W1982728268","https://openalex.org/W1983304433","https://openalex.org/W1986044514","https://openalex.org/W1986357594","https://openalex.org/W1986407340","https://openalex.org/W1987468753","https://openalex.org/W1988195734","https://openalex.org/W1989629861","https://openalex.org/W1995089537","https://openalex.org/W1997355076","https://openalex.org/W1999513758","https://openalex.org/W1999862493","https://openalex.org/W2000314850","https://openalex.org/W2005361085","https://openalex.org/W2010233441","https://openalex.org/W2010453137","https://openalex.org/W2011877643","https://openalex.org/W2011997097","https://openalex.org/W2013760445","https://openalex.org/W2015438966","https://openalex.org/W2016619479","https://openalex.org/W2017552574","https://openalex.org/W2018632273","https://openalex.org/W2020859943","https://openalex.org/W2021295492","https://openalex.org/W2021720722","https://openalex.org/W2022998385","https://openalex.org/W2025580327","https://openalex.org/W2025768430","https://openalex.org/W2026256694","https://openalex.org/W2029082950","https://openalex.org/W2031390939","https://openalex.org/W2032008870","https://openalex.org/W2042110087","https://openalex.org/W2042848688","https://openalex.org/W2044172327","https://openalex.org/W2045839774","https://openalex.org/W2046589863","https://openalex.org/W2046891749","https://openalex.org/W2046929309","https://openalex.org/W2049423932","https://openalex.org/W2049617155","https://openalex.org/W2050537711","https://openalex.org/W2052014829","https://openalex.org/W2052030759","https://openalex.org/W2052214665","https://openalex.org/W2052226480","https://openalex.org/W2052260244","https://openalex.org/W2053253524","https://openalex.org/W2053717624","https://openalex.org/W2055800653","https://openalex.org/W2057461700","https://openalex.org/W2060153789","https://openalex.org/W2060907336","https://openalex.org/W2061111857","https://openalex.org/W2061799302","https://openalex.org/W2064073012","https://openalex.org/W2065380210","https://openalex.org/W2065963893","https://openalex.org/W2068113002","https://openalex.org/W2070930739","https://openalex.org/W2073150308","https://openalex.org/W2076779016","https://openalex.org/W2077388991","https://openalex.org/W2079277579","https://openalex.org/W2081123119","https://openalex.org/W2081930221","https://openalex.org/W2082032299","https://openalex.org/W2085098005","https://openalex.org/W2090198980","https://openalex.org/W2095719702","https://openalex.org/W2095727900","https://openalex.org/W2096541451","https://openalex.org/W2097117768","https://openalex.org/W2097936772","https://openalex.org/W2098474053","https://openalex.org/W2103300124","https://openalex.org/W2103496339","https://openalex.org/W2112411768","https://openalex.org/W2112857740","https://openalex.org/W2113149246","https://openalex.org/W2118233996","https://openalex.org/W2122111042","https://openalex.org/W2122174098","https://openalex.org/W2122538988","https://openalex.org/W2126963755","https://openalex.org/W2129269041","https://openalex.org/W2130082288","https://openalex.org/W2130421583","https://openalex.org/W2132094707","https://openalex.org/W2132820240","https://openalex.org/W2132925790","https://openalex.org/W2134967712","https://openalex.org/W2135893370","https://openalex.org/W2137454940","https://openalex.org/W2138972881","https://openalex.org/W2144342646","https://openalex.org/W2147088528","https://openalex.org/W2149137320","https://openalex.org/W2149706766","https://openalex.org/W2152630148","https://openalex.org/W2156053468","https://openalex.org/W2157177751","https://openalex.org/W2157319908","https://openalex.org/W2158019033","https://openalex.org/W2158071704","https://openalex.org/W2159887157","https://openalex.org/W2165960883","https://openalex.org/W2167960276","https://openalex.org/W2169678694","https://openalex.org/W2170564629","https://openalex.org/W2170915616","https://openalex.org/W2172024214","https://openalex.org/W2177317049","https://openalex.org/W2189308973","https://openalex.org/W2189911347","https://openalex.org/W2200767428","https://openalex.org/W2204695023","https://openalex.org/W2206954826","https://openalex.org/W2207671224","https://openalex.org/W2213831903","https://openalex.org/W2217770415","https://openalex.org/W2264043469","https://openalex.org/W2273267066","https://openalex.org/W2295124130","https://openalex.org/W2296609147","https://openalex.org/W2297106365","https://openalex.org/W2321278764","https://openalex.org/W2333941540","https://openalex.org/W2339337816","https://openalex.org/W2342221852","https://openalex.org/W2379628571","https://openalex.org/W2406455777","https://openalex.org/W2436108096","https://openalex.org/W2467013363","https://openalex.org/W2467309505","https://openalex.org/W2502949459","https://openalex.org/W2526925775","https://openalex.org/W2529996553","https://openalex.org/W2550447077","https://openalex.org/W2550887636","https://openalex.org/W2565379041","https://openalex.org/W2572080171","https://openalex.org/W2581082771","https://openalex.org/W2583907533","https://openalex.org/W2591077138","https://openalex.org/W2592742128","https://openalex.org/W2593436234","https://openalex.org/W2606967831","https://openalex.org/W2608559058","https://openalex.org/W2615180420","https://openalex.org/W2620001003","https://openalex.org/W2624903548","https://openalex.org/W2734784508","https://openalex.org/W2734982589","https://openalex.org/W2739354616","https://openalex.org/W2741312552","https://openalex.org/W2761181345","https://openalex.org/W2765593915","https://openalex.org/W2766178498","https://openalex.org/W2767812299","https://openalex.org/W2767891136","https://openalex.org/W2768702618","https://openalex.org/W2773963615","https://openalex.org/W2773987374","https://openalex.org/W2783666262","https://openalex.org/W2784226073","https://openalex.org/W2791189603","https://openalex.org/W2791704581","https://openalex.org/W2792455800","https://openalex.org/W2792993918","https://openalex.org/W2795068716","https://openalex.org/W2795741784","https://openalex.org/W2801991413","https://openalex.org/W2805310212","https://openalex.org/W2810023675","https://openalex.org/W2810207189","https://openalex.org/W2810711993","https://openalex.org/W2869436908","https://openalex.org/W2884344286","https://openalex.org/W2885954425","https://openalex.org/W2886544065","https://openalex.org/W2889231363","https://openalex.org/W2889291453","https://openalex.org/W2890948746","https://openalex.org/W2891608802","https://openalex.org/W2891838559","https://openalex.org/W2893435209","https://openalex.org/W2893455886","https://openalex.org/W2894573731","https://openalex.org/W2895370006","https://openalex.org/W2895420596","https://openalex.org/W2898391595","https://openalex.org/W2898567607","https://openalex.org/W2899070097","https://openalex.org/W2899881745","https://openalex.org/W2900090807","https://openalex.org/W2902189168","https://openalex.org/W2902225381","https://openalex.org/W2902329228","https://openalex.org/W2904742480","https://openalex.org/W2905665749","https://openalex.org/W2910096450","https://openalex.org/W2910793948","https://openalex.org/W2911658570","https://openalex.org/W2911964244","https://openalex.org/W2912159735","https://openalex.org/W2913256647","https://openalex.org/W2919115771","https://openalex.org/W2921321912","https://openalex.org/W2924066922","https://openalex.org/W2937307539","https://openalex.org/W2942390636","https://openalex.org/W2944872342","https://openalex.org/W2945755098","https://openalex.org/W2948387511","https://openalex.org/W2948691445","https://openalex.org/W2948831670","https://openalex.org/W2950336271","https://openalex.org/W2951730672","https://openalex.org/W2957116182","https://openalex.org/W2959938226","https://openalex.org/W2961050676","https://openalex.org/W2961918648","https://openalex.org/W2963974552","https://openalex.org/W2966984447","https://openalex.org/W2969625533","https://openalex.org/W2969790209","https://openalex.org/W2970093742","https://openalex.org/W2971690404","https://openalex.org/W2971801381","https://openalex.org/W2972497960","https://openalex.org/W2973041138","https://openalex.org/W2975256032","https://openalex.org/W2981997745","https://openalex.org/W2989611985","https://openalex.org/W2991090734","https://openalex.org/W2995098893","https://openalex.org/W2995153909","https://openalex.org/W2995472818","https://openalex.org/W2998916227","https://openalex.org/W2998982556","https://openalex.org/W2999044305","https://openalex.org/W2999309192","https://openalex.org/W3000982932","https://openalex.org/W3003076402","https://openalex.org/W3004306282","https://openalex.org/W3005064662","https://openalex.org/W3006759222","https://openalex.org/W3007215678","https://openalex.org/W3007309629","https://openalex.org/W3008194656","https://openalex.org/W3009341801","https://openalex.org/W3009535750","https://openalex.org/W3010521003","https://openalex.org/W3010761615","https://openalex.org/W3013702826","https://openalex.org/W3016322008","https://openalex.org/W3017040425","https://openalex.org/W3017681976","https://openalex.org/W3019944201","https://openalex.org/W3021338900","https://openalex.org/W3023126697","https://openalex.org/W3025501158","https://openalex.org/W3026166203","https://openalex.org/W3027099090","https://openalex.org/W3027975282","https://openalex.org/W3032905047","https://openalex.org/W3035777330","https://openalex.org/W3044326329","https://openalex.org/W3045129895","https://openalex.org/W3047285698","https://openalex.org/W3084814365","https://openalex.org/W3084873012","https://openalex.org/W3085429933","https://openalex.org/W3092122663","https://openalex.org/W3092524006","https://openalex.org/W3092712933","https://openalex.org/W3093683180","https://openalex.org/W3094492244","https://openalex.org/W3094540299","https://openalex.org/W3094640617","https://openalex.org/W3094948156","https://openalex.org/W3097145107","https://openalex.org/W3099252273","https://openalex.org/W3102745472","https://openalex.org/W3107685887","https://openalex.org/W3109240549","https://openalex.org/W3111632399","https://openalex.org/W3112587790","https://openalex.org/W3112951420","https://openalex.org/W3116664634","https://openalex.org/W3119109946","https://openalex.org/W3119952098","https://openalex.org/W3120945079","https://openalex.org/W3124409690","https://openalex.org/W3124602313","https://openalex.org/W3126232929","https://openalex.org/W3127347132","https://openalex.org/W3127380163","https://openalex.org/W3130580848","https://openalex.org/W3133246485","https://openalex.org/W3146518000","https://openalex.org/W3147809485","https://openalex.org/W3150885974","https://openalex.org/W3153418506","https://openalex.org/W3156323934","https://openalex.org/W3157142404","https://openalex.org/W3157442619","https://openalex.org/W3157590392","https://openalex.org/W3157853087","https://openalex.org/W3158529618","https://openalex.org/W3159514218","https://openalex.org/W3164039743","https://openalex.org/W3164651207","https://openalex.org/W3165163721","https://openalex.org/W3165588155","https://openalex.org/W3167619859","https://openalex.org/W3169629772","https://openalex.org/W3173957093","https://openalex.org/W3177828909","https://openalex.org/W3183046872","https://openalex.org/W3183921815","https://openalex.org/W3185358186","https://openalex.org/W3185433118","https://openalex.org/W3185883045","https://openalex.org/W3186179742","https://openalex.org/W3188673779","https://openalex.org/W3194368700","https://openalex.org/W3198655865","https://openalex.org/W3199618438","https://openalex.org/W3200607218","https://openalex.org/W3204312334","https://openalex.org/W3205954843","https://openalex.org/W3206629920","https://openalex.org/W3208245668","https://openalex.org/W3209901185","https://openalex.org/W3215689235","https://openalex.org/W4200278641","https://openalex.org/W4200494048","https://openalex.org/W4205411722","https://openalex.org/W4205739101","https://openalex.org/W4205989934","https://openalex.org/W4206085705","https://openalex.org/W4241533019","https://openalex.org/W4249837478","https://openalex.org/W4253667136","https://openalex.org/W4255056905"],"related_works":["https://openalex.org/W3167619859","https://openalex.org/W4309013036","https://openalex.org/W2974690583","https://openalex.org/W4412158471","https://openalex.org/W3153418506","https://openalex.org/W7153103124","https://openalex.org/W7140186529","https://openalex.org/W4417146796","https://openalex.org/W4407374846","https://openalex.org/W7118270799"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,67],"lengthy":[2],"and":[3,15,30,57,82,90,107,130,163,183,188,201,221],"expensive":[4],"process":[5],"of":[6,32,40,59,69,78,93,99,140,149,185],"developing":[7],"a":[8,17,44],"novel":[9],"medicine":[10],"often":[11],"takes":[12],"many":[13,97,160],"years":[14],"entails":[16],"significant":[18],"financial":[19],"burden":[20],"due":[21],"to":[22,53,74,87,120,235],"its":[23],"poor":[24],"success":[25],"rate.":[26],"Furthermore,":[27],"the":[28,38,55,79,91,147,159,212,219,225],"processing":[29],"analysis":[31,72],"quickly":[33],"expanding":[34],"massive":[35],"data":[36,142],"necessitate":[37],"use":[39,92],"cutting-edge":[41],"methodologies.":[42],"As":[43],"result,":[45],"Artificial":[46,94,168,205,239],"Intelligence-driven":[47],"methods":[48,125],"that":[49,144,229],"have":[50,62,110,152],"been":[51,111,154],"shown":[52],"improve":[54],"efficiency":[56],"accuracy":[58],"drug":[60,80,88,100,104,192,241],"discovery":[61,81,151,193],"grown":[63],"in":[64,96,113,127,135,191,224,238],"favor.":[65],"OBJECTIVE:":[66],"goal":[68],"this":[70,114,230],"thorough":[71],"is":[73],"provide":[75],"an":[76,118],"overview":[77],"development":[83,105],"timeline,":[84],"various":[85],"approaches":[86,106],"design,":[89],"Intelligence":[95],"aspects":[98],"discovery.":[101],"METHODS:":[102],"Traditional":[103],"their":[108,199],"disadvantages":[109],"explored":[112],"paper,":[115],"followed":[116],"by":[117,210],"introduction":[119],"AI-based":[121],"technology.":[122],"Also,":[123],"advanced":[124],"used":[126],"Machine":[128,186],"Learning":[129,132,170,187,190],"Deep":[131,189],"are":[133,158,194],"examined":[134],"detail.":[136],"A":[137],"few":[138],"examples":[139],"big":[141],"research":[143],"has":[145],"transformed":[146],"field":[148],"medication":[150],"also":[153],"presented.":[155],"Also":[156],"covered":[157],"databases,":[161],"toolkits,":[162],"software":[164],"available":[165,214],"for":[166],"constructing":[167],"Intelligence/Machine":[169],"models,":[171],"as":[172,174],"well":[173],"some":[175],"standard":[176],"model":[177],"evaluation":[178],"parameters.":[179],"Finally,":[180],"recent":[181],"advances":[182],"uses":[184],"thoroughly":[195],"examined,":[196],"along":[197],"with":[198],"limitations":[200],"future":[202],"potential.":[203],"CONCLUSION:":[204],"Intelligence-based":[206],"technologies":[207],"enhance":[208],"decision-making":[209],"utilizing":[211],"abundantly":[213],"high-quality":[215],"data,":[216],"thereby":[217],"reducing":[218],"time":[220],"cost":[222],"involved":[223],"process.":[226],"We":[227],"anticipate":[228],"review":[231],"would":[232],"be":[233],"useful":[234],"researchers":[236],"interested":[237],"Intelligencebased":[240],"development.":[242]},"counts_by_year":[{"year":2026,"cited_by_count":23},{"year":2025,"cited_by_count":34},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-07-05T00:00:00"}