{"id":"https://openalex.org/W4283759571","doi":"https://doi.org/10.30872/j.trop.pharm.chem.v6i1.215","title":"Use of CMC Na as Gelling Agent in Nanoemulgel Formulation of Methanol Extract of Sappan Wood (Caesalpinia sappan L)","display_name":"Use of CMC Na as Gelling Agent in Nanoemulgel Formulation of Methanol Extract of Sappan Wood (Caesalpinia sappan L)","publication_year":2022,"publication_date":"2022-06-30","ids":{"openalex":"https://openalex.org/W4283759571","doi":"https://doi.org/10.30872/j.trop.pharm.chem.v6i1.215"},"language":"en","primary_location":{"id":"doi:10.30872/j.trop.pharm.chem.v6i1.215","doi":"https://doi.org/10.30872/j.trop.pharm.chem.v6i1.215","is_oa":true,"landing_page_url":"https://doi.org/10.30872/j.trop.pharm.chem.v6i1.215","pdf_url":"http://jtpc.ff.unmul.ac.id/index.php/jtpc/article/download/215/211","source":{"id":"https://openalex.org/S2764682861","display_name":"Journal Of Tropical Pharmacy And Chemistry","issn_l":"2087-7099","issn":["2087-7099","2407-6090"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315167","host_organization_name":"Mulawarman University","host_organization_lineage":["https://openalex.org/P4310315167"],"host_organization_lineage_names":["Mulawarman University"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Tropical Pharmacy and Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://jtpc.ff.unmul.ac.id/index.php/jtpc/article/download/215/211","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061202567","display_name":"Dwi Saryanti","orcid":"https://orcid.org/0000-0001-6405-628X","observed_orcids":["https://orcid.org/0000-0001-6405-628X"]},"institutions":[{"id":"https://openalex.org/I4405261734","display_name":"Sekolah Tinggi Ilmu Kesehatan Nasional","ror":"https://ror.org/05rt4ed39","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405261734"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Dwi Saryanti","raw_affiliation_strings":["Departemen Teknologi Farmasi Program Studi DIII Farmasi Stikes Nasional"],"raw_orcid":"https://orcid.org/0000-0001-6405-628X","affiliations":[{"raw_affiliation_string":"Departemen Teknologi Farmasi Program Studi DIII Farmasi Stikes Nasional","institution_ids":["https://openalex.org/I4405261734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071699768","display_name":"Iwan Budi Setiawan","orcid":"https://orcid.org/0000-0002-5658-8064","observed_orcids":["https://orcid.org/0000-0002-5658-8064"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Iwan Setiawan","raw_affiliation_strings":["Department of Pharmaceutical Technology, Diploma of Pharmacy, Nasional College of Health Science, Jalan Solo-Baki Kwarasan, Grogol, Sukoharjo, Jawa Tengah,57552, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Technology, Diploma of Pharmacy, Nasional College of Health Science, Jalan Solo-Baki Kwarasan, Grogol, Sukoharjo, Jawa Tengah,57552, Indonesia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009354044","display_name":"Hendri Hari Dayanto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hendri Hari Dayanto","raw_affiliation_strings":["Department of Traditional Medicine Diploma of Pharmacy, Nasional College of Health Science, Jalan Solo-Baki Kwarasan, Grogol, Sukoharjo, Jawa Tengah,57552, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Traditional Medicine Diploma of Pharmacy, Nasional College of Health Science, Jalan Solo-Baki Kwarasan, Grogol, Sukoharjo, Jawa Tengah,57552, Indonesia","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.223,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.7114238,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":"1","first_page":"21","last_page":"29"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caesalpinia-sappan","display_name":"Caesalpinia sappan","score":0.9010000228881836},{"id":"https://openalex.org/keywords/sappan-wood-extract","display_name":"sappan wood extract","score":0.8840000033378601},{"id":"https://openalex.org/keywords/nanoemulgel","display_name":"nanoemulgel","score":0.9520000219345093},{"id":"https://openalex.org/keywords/sodium-carboxymethyl-cellulose","display_name":"sodium carboxymethyl cellulose","score":0.9150000214576721},{"id":"https://openalex.org/keywords/gelling-agent-concentration","display_name":"gelling agent concentration","score":0.9670000076293945},{"id":"https://openalex.org/keywords/nanoemulsions","display_name":"nanoemulsions","score":0.9399999976158142},{"id":"https://openalex.org/keywords/isoflavonoids","display_name":"isoflavonoids","score":0.824999988079071},{"id":"https://openalex.org/keywords/brazilin","display_name":"brazilin","score":0.9729999899864197},{"id":"https://openalex.org/keywords/topical-preparations","display_name":"topical formulation","score":0.593999981880188},{"id":"https://openalex.org/keywords/adhesion","display_name":"adhesion","score":0.460999995470047},{"id":"https://openalex.org/keywords/spreadability","display_name":"spreadability","score":0.796999990940094},{"id":"https://openalex.org/keywords/viscosity","display_name":"viscosity","score":0.7730000019073486},{"id":"https://openalex.org/keywords/freeze-thaw-stability","display_name":"freeze-thaw stability","score":0.8629999756813049},{"id":"https://openalex.org/keywords/isopropyl-myristate","display_name":"isopropyl myristate","score":0.8069999814033508},{"id":"https://openalex.org/keywords/tween-80","display_name":"Tween 80","score":0.8600000143051147},{"id":"https://openalex.org/keywords/polyethylene-glycol","display_name":"polyethylene glycol","score":0.9380000233650208}],"concepts":[{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.6721763610839844},{"id":"https://openalex.org/C2779783494","wikidata":"https://www.wikidata.org/wiki/Q416222","display_name":"Isopropyl myristate","level":2,"score":0.6691680550575256},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6078916192054749},{"id":"https://openalex.org/C2778123984","wikidata":"https://www.wikidata.org/wiki/Q187634","display_name":"Emulsion","level":2,"score":0.5626792311668396},{"id":"https://openalex.org/C190119865","wikidata":"https://www.wikidata.org/wiki/Q338019","display_name":"Microemulsion","level":3,"score":0.5370392203330994},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5337188243865967},{"id":"https://openalex.org/C2993661896","wikidata":"https://www.wikidata.org/wiki/Q6557468","display_name":"Liquid paraffin","level":2,"score":0.46063029766082764},{"id":"https://openalex.org/C68928338","wikidata":"https://www.wikidata.org/wiki/Q131790","display_name":"Adhesive","level":3,"score":0.42592746019363403},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2849043011665344},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1987459659576416},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.08647847175598145},{"id":"https://openalex.org/C2779227376","wikidata":"https://www.wikidata.org/wiki/Q6505497","display_name":"Layer (electronics)","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.30872/j.trop.pharm.chem.v6i1.215","doi":"https://doi.org/10.30872/j.trop.pharm.chem.v6i1.215","is_oa":true,"landing_page_url":"https://doi.org/10.30872/j.trop.pharm.chem.v6i1.215","pdf_url":"http://jtpc.ff.unmul.ac.id/index.php/jtpc/article/download/215/211","source":{"id":"https://openalex.org/S2764682861","display_name":"Journal Of Tropical Pharmacy And Chemistry","issn_l":"2087-7099","issn":["2087-7099","2407-6090"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315167","host_organization_name":"Mulawarman University","host_organization_lineage":["https://openalex.org/P4310315167"],"host_organization_lineage_names":["Mulawarman University"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Tropical Pharmacy and Chemistry","raw_type":"journal-article"},{"id":"doi:10.25026/jtpc.v6i1.276","doi":"https://doi.org/10.25026/jtpc.v6i1.276","is_oa":true,"landing_page_url":"https://doi.org/10.25026/jtpc.v6i1.276","pdf_url":"https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/download/276/251","source":{"id":"https://openalex.org/S2764682861","display_name":"Journal Of Tropical Pharmacy And Chemistry","issn_l":"2087-7099","issn":["2087-7099","2407-6090"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315167","host_organization_name":"Mulawarman University","host_organization_lineage":["https://openalex.org/P4310315167"],"host_organization_lineage_names":["Mulawarman University"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Tropical Pharmacy and Chemistry","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.30872/j.trop.pharm.chem.v6i1.215","doi":"https://doi.org/10.30872/j.trop.pharm.chem.v6i1.215","is_oa":true,"landing_page_url":"https://doi.org/10.30872/j.trop.pharm.chem.v6i1.215","pdf_url":"http://jtpc.ff.unmul.ac.id/index.php/jtpc/article/download/215/211","source":{"id":"https://openalex.org/S2764682861","display_name":"Journal Of Tropical Pharmacy And Chemistry","issn_l":"2087-7099","issn":["2087-7099","2407-6090"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315167","host_organization_name":"Mulawarman University","host_organization_lineage":["https://openalex.org/P4310315167"],"host_organization_lineage_names":["Mulawarman University"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Tropical Pharmacy and Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4283759571.pdf","grobid_xml":"https://content.openalex.org/works/W4283759571.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W393707166","https://openalex.org/W795685724","https://openalex.org/W1842037677","https://openalex.org/W1930589421","https://openalex.org/W2074165114","https://openalex.org/W2199774667","https://openalex.org/W2337015819","https://openalex.org/W2419534103","https://openalex.org/W2472154606","https://openalex.org/W2493475775","https://openalex.org/W2766669147","https://openalex.org/W2772654019","https://openalex.org/W3207371654","https://openalex.org/W6600392996"],"related_works":["https://openalex.org/W3181871009","https://openalex.org/W7172442617","https://openalex.org/W7047307823","https://openalex.org/W2907871088","https://openalex.org/W126330784","https://openalex.org/W4387654044","https://openalex.org/W4392924090","https://openalex.org/W2320452380","https://openalex.org/W3196289938","https://openalex.org/W4391515858"],"abstract_inverted_index":{"Sappan":[0],"wood":[1,166,213],"(":[2,215],"Caesalpinia":[3,216],"sappan":[4,212,217],"L.)":[5,218],"contains":[6],"brazilin":[7],"including":[8],"isoflavonoids":[9],"which":[10,87],"act":[11],"as":[12,105,110,114,176],"antimicrobials":[13],"(against":[14],"bacteria":[15],"on":[16,47,171],"skin)":[17],"and":[18,33,56,86,112,146,160,179,195],"antioxidants.":[19],"Nano":[20,38],"technology":[21],"increases":[22],"surface":[23],"area,":[24],"enhance":[25],"stability,":[26],"reduces":[27],"skin":[28],"irritation,":[29],"protects":[30],"from":[31,102,135],"degradation,":[32],"has":[34],"good":[35,57],"drug":[36,46,58],"delivery.":[37],"emulsion":[39],"preparations":[40,52,167],"can":[41,53,94],"help":[42],"permeability":[43],"of":[44,71,79,82,89,122,140,157,163,184,203,211],"the":[45,48,77,96,164,172,181,191,198,209],"membrane":[49],"surface.":[50],"Nanoemulgel":[51,132],"provide":[54],"stability":[55,161],"release":[59],"compared":[60],"to":[61,75],"mixing":[62],"drugs":[63],"directly":[64],"in":[65,188],"a":[66,129],"gel":[67],"base.":[68],"The":[69,148,155],"purpose":[70],"this":[72],"study":[73],"were":[74,118],"determine":[76],"effect":[78],"different":[80],"concentrations":[81,143],"CMC-Na":[83,90,141,185,204],"gelling":[84,91,186,205],"agents":[85,92,187],"concentration":[88,183],"that":[93,207,221],"produce":[95],"best":[97,210],"nanoemulgel":[98,189,214],"preparations.":[99],"Nanoemulsion":[100,116],"made":[101,134],"isopropyl":[103],"myristate":[104],"oil":[106],"phase,":[107],"tween":[108],"80":[109],"surfactant":[111],"polyethylenglycol":[113],"co-surfactant.":[115],"formulations":[117],"tested":[119],"by":[120,125,223],"measurement":[121],"%":[123],"transmittance":[124,152],"UV-Vis":[126],"spectrophotometry":[127],"at":[128,142],"wavelength":[130],"650nm.":[131],"is":[133],"nano":[136],"emulsions":[137],"used":[138],"basis":[139],"3%,":[144],"4%,":[145],"5%.":[147],"results":[149,156],"showed":[150,168],"percent":[151],"was":[153,200,219],"71.86%.":[154],"physical":[158,173],"quality":[159],"tests":[162],"nanomulgel":[165],"an":[169],"influence":[170],"properties":[174],"such":[175],"adhesion,":[177],"dispersion":[178],"viscosity,":[180,196],"greater":[182,192],"preparations,":[190],"values":[193],"adhesion":[194],"while":[197],"spreadability":[199],"smaller.":[201],"Concentration":[202],"agent":[206],"produced":[208],"5%":[220],"stable":[222],"freeze-thaw":[224],"testing.":[225]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2022-07-02T00:00:00"}