{"id":"https://openalex.org/W4283662657","doi":"https://doi.org/10.7759/cureus.26390","title":"The Role and Effectiveness of Photodynamic Therapy on Patients With Actinic Keratosis: A Systematic Review and Meta-Analysis","display_name":"The Role and Effectiveness of Photodynamic Therapy on Patients With Actinic Keratosis: A Systematic Review and Meta-Analysis","publication_year":2022,"publication_date":"2022-06-28","ids":{"openalex":"https://openalex.org/W4283662657","doi":"https://doi.org/10.7759/cureus.26390","pmid":"https://pubmed.ncbi.nlm.nih.gov/35911353","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9332024"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.26390","doi":"https://doi.org/10.7759/cureus.26390","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.26390","pdf_url":"https://www.cureus.com/articles/101471-the-role-and-effectiveness-of-photodynamic-therapy-on-patients-with-actinic-keratosis-a-systematic-review-and-meta-analysis.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/101471-the-role-and-effectiveness-of-photodynamic-therapy-on-patients-with-actinic-keratosis-a-systematic-review-and-meta-analysis.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056193435","display_name":"George Mpourazanis","orcid":"https://orcid.org/0000-0002-5844-9770","observed_orcids":["https://orcid.org/0000-0002-5844-9770"]},"institutions":[{"id":"https://openalex.org/I4210113563","display_name":"General Hospital of Ioannina G. Hatzikosta","ror":"https://ror.org/01yn28w07","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210113563"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"George Mpourazanis","raw_affiliation_strings":["Department of Obstetrics and Gynecology, General Hospital of Ioannina G. Hatzikosta, Ioannina, GRC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, General Hospital of Ioannina G. Hatzikosta, Ioannina, GRC","institution_ids":["https://openalex.org/I4210113563"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014218501","display_name":"Wolfgang Konschake","orcid":"https://orcid.org/0000-0003-4860-5925","observed_orcids":["https://orcid.org/0000-0003-4860-5925"]},"institutions":[{"id":"https://openalex.org/I2799318839","display_name":"Universit\u00e4tsmedizin Greifswald","ror":"https://ror.org/025vngs54","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799318839"]},{"id":"https://openalex.org/I36522303","display_name":"Universit\u00e4t Greifswald","ror":"https://ror.org/00r1edq15","country_code":"DE","type":"education","lineage":["https://openalex.org/I36522303"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wolfgang Konschake","raw_affiliation_strings":["Department of Dermatology, Ernst-Moritz-Arndt Medical University of Greifswald, Greifswald, DEU"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Ernst-Moritz-Arndt Medical University of Greifswald, Greifswald, DEU","institution_ids":["https://openalex.org/I2799318839","https://openalex.org/I36522303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002907346","display_name":"Romanos Vogiatzis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799318839","display_name":"Universit\u00e4tsmedizin Greifswald","ror":"https://ror.org/025vngs54","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799318839"]},{"id":"https://openalex.org/I36522303","display_name":"Universit\u00e4t Greifswald","ror":"https://ror.org/00r1edq15","country_code":"DE","type":"education","lineage":["https://openalex.org/I36522303"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Romanos Vogiatzis","raw_affiliation_strings":["Department of Dermatology, Ernst-Moritz-Arndt Medical University of Greifswald, Greifswald, DEU"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Ernst-Moritz-Arndt Medical University of Greifswald, Greifswald, DEU","institution_ids":["https://openalex.org/I2799318839","https://openalex.org/I36522303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066821160","display_name":"Petros Papalexis","orcid":"https://orcid.org/0000-0003-3565-4066","observed_orcids":["https://orcid.org/0000-0003-3565-4066"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]},{"id":"https://openalex.org/I21370196","display_name":"Aristotle University of Thessaloniki","ror":"https://ror.org/02j61yw88","country_code":"GR","type":"education","lineage":["https://openalex.org/I21370196"]},{"id":"https://openalex.org/I4210114623","display_name":"Laiko General Hospital of Athens","ror":"https://ror.org/02dvs1389","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210114623"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Petros Papalexis","raw_affiliation_strings":["Department of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC","Unit of Endocrinology, First Department of Internal Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, GRC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC","institution_ids":["https://openalex.org/I21370196"]},{"raw_affiliation_string":"Unit of Endocrinology, First Department of Internal Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, GRC","institution_ids":["https://openalex.org/I200777214","https://openalex.org/I4210114623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047101639","display_name":"Vasiliki Georgakopoulou","orcid":"https://orcid.org/0000-0003-0772-811X","observed_orcids":["https://orcid.org/0000-0003-0772-811X"]},"institutions":[{"id":"https://openalex.org/I2800888565","display_name":"Sismanoglio General Hospital","ror":"https://ror.org/057cm0m66","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I2800888565"]},{"id":"https://openalex.org/I4210114623","display_name":"Laiko General Hospital of Athens","ror":"https://ror.org/02dvs1389","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210114623"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Vasiliki E Georgakopoulou","raw_affiliation_strings":["Department of Pulmonology, Laiko General Hospital, Athens, GRC","First Department of Pulmonology, Sismanogleio Hospital, Athens, GRC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pulmonology, Laiko General Hospital, Athens, GRC","institution_ids":["https://openalex.org/I4210114623"]},{"raw_affiliation_string":"First Department of Pulmonology, Sismanogleio Hospital, Athens, GRC","institution_ids":["https://openalex.org/I2800888565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024854691","display_name":"Georgios Ntritsos","orcid":"https://orcid.org/0000-0002-6213-2901","observed_orcids":["https://orcid.org/0000-0002-6213-2901"]},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Georgios Ntritsos","raw_affiliation_strings":["Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, GRC","Department of Informatics and Telecommunications, School of Informatics and Telecommunications, University of Ioannina, Arta, GRC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, GRC","institution_ids":["https://openalex.org/I194019607"]},{"raw_affiliation_string":"Department of Informatics and Telecommunications, School of Informatics and Telecommunications, University of Ioannina, Arta, GRC","institution_ids":["https://openalex.org/I194019607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063682586","display_name":"Pagona Sklapani","orcid":"https://orcid.org/0000-0001-7347-8433","observed_orcids":["https://orcid.org/0000-0001-7347-8433"]},"institutions":[{"id":"https://openalex.org/I4210122009","display_name":"Hygeia Hospital","ror":"https://ror.org/03qv5tx95","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210122009"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Pagona Sklapani","raw_affiliation_strings":["Department of Cytology, Mitera-Hygeia Hospital, Athens, GRC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cytology, Mitera-Hygeia Hospital, Athens, GRC","institution_ids":["https://openalex.org/I4210122009"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017303419","display_name":"\u039d\u03b9\u03ba\u03cc\u03bb\u03b1\u03bf\u03c2 \u03a4\u03c1\u03ac\u03ba\u03b1\u03c2","orcid":"https://orcid.org/0000-0001-8157-1304","observed_orcids":["https://orcid.org/0000-0001-8157-1304"]},"institutions":[{"id":"https://openalex.org/I2800888565","display_name":"Sismanoglio General Hospital","ror":"https://ror.org/057cm0m66","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I2800888565"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Nikolaos Trakas","raw_affiliation_strings":["Department of Biochemistry, Sismanogleio Hospital, Athens, GRC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Sismanogleio Hospital, Athens, GRC","institution_ids":["https://openalex.org/I2800888565"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5017303419"],"corresponding_institution_ids":["https://openalex.org/I2800888565"],"apc_list":null,"apc_paid":null,"fwci":0.3009,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.25668754,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"14","issue":"6","first_page":"e26390","last_page":"e26390"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/photodynamic-therapy","display_name":"photodynamic therapy","score":0.9549999833106995},{"id":"https://openalex.org/keywords/actinic-keratosis","display_name":"actinic keratosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/methyl-aminolevulinate","display_name":"methyl aminolevulinate","score":0.9639999866485596},{"id":"https://openalex.org/keywords/5-aminolevulinic-acid","display_name":"5-aminolevulinic acid","score":0.9480000138282776},{"id":"https://openalex.org/keywords/complete-response","display_name":"complete response","score":0.8410000205039978},{"id":"https://openalex.org/keywords/field-cancerization","display_name":"field cancerization","score":0.8360000252723694},{"id":"https://openalex.org/keywords/squamous-cell-carcinoma-prevention","display_name":"squamous cell carcinoma prevention","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C2777873816","wikidata":"https://www.wikidata.org/wiki/Q422225","display_name":"Actinic keratosis","level":3,"score":0.936528205871582},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9168434739112854},{"id":"https://openalex.org/C2781323092","wikidata":"https://www.wikidata.org/wiki/Q1428072","display_name":"Photodynamic therapy","level":2,"score":0.8765898942947388},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6849143505096436},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.6797446608543396},{"id":"https://openalex.org/C60120401","wikidata":"https://www.wikidata.org/wiki/Q17119253","display_name":"Field cancerization","level":3,"score":0.583706796169281},{"id":"https://openalex.org/C2778648961","wikidata":"https://www.wikidata.org/wiki/Q3667186","display_name":"Keratosis","level":2,"score":0.4269615113735199},{"id":"https://openalex.org/C2777789703","wikidata":"https://www.wikidata.org/wiki/Q192102","display_name":"Skin cancer","level":3,"score":0.41876399517059326},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.2946619391441345},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2904064953327179},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2449234127998352},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.26390","doi":"https://doi.org/10.7759/cureus.26390","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.26390","pdf_url":"https://www.cureus.com/articles/101471-the-role-and-effectiveness-of-photodynamic-therapy-on-patients-with-actinic-keratosis-a-systematic-review-and-meta-analysis.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmid:35911353","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35911353","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9332024","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9332024/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7759/cureus.26390","doi":"https://doi.org/10.7759/cureus.26390","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.26390","pdf_url":"https://www.cureus.com/articles/101471-the-role-and-effectiveness-of-photodynamic-therapy-on-patients-with-actinic-keratosis-a-systematic-review-and-meta-analysis.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4283662657.pdf","grobid_xml":"https://content.openalex.org/works/W4283662657.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W187898767","https://openalex.org/W1506108633","https://openalex.org/W1573553697","https://openalex.org/W1678999658","https://openalex.org/W1886857008","https://openalex.org/W1893473681","https://openalex.org/W1915218181","https://openalex.org/W1955184527","https://openalex.org/W1967571683","https://openalex.org/W1992243393","https://openalex.org/W1993827451","https://openalex.org/W1997199704","https://openalex.org/W2000745030","https://openalex.org/W2015471056","https://openalex.org/W2048557233","https://openalex.org/W2049286522","https://openalex.org/W2059916616","https://openalex.org/W2069997181","https://openalex.org/W2103875574","https://openalex.org/W2109887283","https://openalex.org/W2112873380","https://openalex.org/W2119605658","https://openalex.org/W2123757395","https://openalex.org/W2125435699","https://openalex.org/W2125476116","https://openalex.org/W2127010058","https://openalex.org/W2133002266","https://openalex.org/W2141453076","https://openalex.org/W2165588852","https://openalex.org/W2166285207","https://openalex.org/W2171514322","https://openalex.org/W2419610451","https://openalex.org/W2762248324","https://openalex.org/W2805439733","https://openalex.org/W2807271606","https://openalex.org/W2884202979","https://openalex.org/W2884773382","https://openalex.org/W2892501136","https://openalex.org/W2893248400","https://openalex.org/W2897404479","https://openalex.org/W2897699960","https://openalex.org/W2899778862","https://openalex.org/W2912654535","https://openalex.org/W2945785624","https://openalex.org/W2952762499","https://openalex.org/W2991792334","https://openalex.org/W3036211141","https://openalex.org/W3042305574","https://openalex.org/W4242407707","https://openalex.org/W4294215472"],"related_works":["https://openalex.org/W2103875574","https://openalex.org/W4401339573","https://openalex.org/W2960208751","https://openalex.org/W4417085637","https://openalex.org/W2073063125","https://openalex.org/W7110505537","https://openalex.org/W4367840246","https://openalex.org/W2123267299","https://openalex.org/W2401664777","https://openalex.org/W4392813970"],"abstract_inverted_index":{"Actinic":[0],"keratoses":[1],"(AKs)":[2],"are":[3,10],"the":[4,43,58,65,70,103,114,122,134,140],"most":[5],"common":[6],"neoplastic":[7],"lesions":[8],"and":[9,83,98,113],"recognized":[11],"as":[12],"a":[13,24,52,117,129],"precursor":[14],"to":[15,41,56,107],"squamous":[16],"cell":[17],"skin":[18],"cancer.":[19],"Photodynamic":[20],"therapy":[21],"(PDT)":[22],"is":[23],"therapeutic":[25],"option":[26],"for":[27],"multiple":[28],"AKs":[29,50],"in":[30,54,88],"line":[31],"with":[32,49,121],"field":[33],"cancerization.":[34],"The":[35,91],"aim":[36],"of":[37,45,61,79,116,133,142],"this":[38,68],"study":[39],"was":[40],"assess":[42],"effectiveness":[44],"PDT":[46,111],"on":[47,128],"patients":[48],"using":[51],"meta-analysis,":[53],"order":[55],"evaluate":[57],"possible":[59],"superiority":[60],"one":[62],"treatment":[63],"over":[64],"others.":[66],"For":[67],"purpose,":[69],"PubMed,":[71],"MEDLINE,":[72],"Scopus,":[73],"OVID,":[74],"Science":[75],"Direct,":[76],"British":[77],"Journal":[78],"Dermatology,":[80],"Research":[81],"Gate,":[82],"Embase":[84],"databases":[85],"were":[86,95],"searched":[87],"March":[89],"2022.":[90],"search":[92],"terms":[93],"used":[94],"'photodynamic":[96],"therapy'":[97],"'actinic":[99],"keratosis'.":[100],"We":[101],"utilized":[102],"random-effects":[104],"meta-analysis":[105,137],"model":[106],"compare":[108],"methyl":[109],"aminolevulinate":[110],"(MAL-PDT)":[112],"combination":[115],"nanoscale-lipid":[118],"vesicle":[119],"formulation":[120],"prodrug":[123],"5-aminolevulinic":[124],"acid":[125],"(BF-200":[126],"ALA)":[127],"complete":[130],"response":[131],"(CR)":[132],"lesions.":[135],"Our":[136],"indicated":[138],"that":[139],"comparison":[141],"BF-200":[143],"ALA":[144],"versus":[145],"MAL-PDT":[146],"showed":[147],"marginally":[148],"higher":[149],"CRs":[150],"than":[151],"MAL-PDT.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2022-06-29T00:00:00"}
