{"id":"https://openalex.org/W4283662630","doi":"https://doi.org/10.1039/d2cb00100d","title":"Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides","display_name":"Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4283662630","doi":"https://doi.org/10.1039/d2cb00100d","pmid":"https://pubmed.ncbi.nlm.nih.gov/35755188","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9175110"},"language":"en","primary_location":{"id":"doi:10.1039/d2cb00100d","doi":"https://doi.org/10.1039/d2cb00100d","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d2cb00100d","pdf_url":null,"source":{"id":"https://openalex.org/S4210222191","display_name":"RSC Chemical Biology","issn_l":"2633-0679","issn":["2633-0679"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Chemical Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1039/d2cb00100d","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030108505","display_name":"Anna Dysko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anna Dysko","raw_affiliation_strings":["Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060881547","display_name":"Ysobel R. Baker","orcid":"https://orcid.org/0000-0002-0266-771X","observed_orcids":["https://orcid.org/0000-0002-0266-771X"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ysobel R. Baker","raw_affiliation_strings":["Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK"],"raw_orcid":"https://orcid.org/0000-0002-0266-771X","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112697154","display_name":"Graham McClorey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Graham McClorey","raw_affiliation_strings":["Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089279578","display_name":"Matthew J. A. Wood","orcid":"https://orcid.org/0000-0002-5436-6011","observed_orcids":["https://orcid.org/0000-0002-5436-6011"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matthew J. A. Wood","raw_affiliation_strings":["Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049108784","display_name":"Sabine Fenner","orcid":"https://orcid.org/0000-0003-1465-8105","observed_orcids":["https://orcid.org/0000-0003-1465-8105"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sabine Fenner","raw_affiliation_strings":["GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008274449","display_name":"Glynn D. Williams","orcid":"https://orcid.org/0000-0002-7798-7929","observed_orcids":["https://orcid.org/0000-0002-7798-7929"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Glynn Williams","raw_affiliation_strings":["GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068579148","display_name":"Afaf Helmy El-Sagheer","orcid":"https://orcid.org/0000-0001-8706-1292","observed_orcids":["https://orcid.org/0000-0001-8706-1292"]},"institutions":[{"id":"https://openalex.org/I130009713","display_name":"Suez University","ror":"https://ror.org/00ndhrx30","country_code":"EG","type":"education","lineage":["https://openalex.org/I130009713"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["EG","GB"],"is_corresponding":false,"raw_author_name":"Afaf El-Sagheer","raw_affiliation_strings":["Chemistry Branch Department of Science and Mathematics, Faculty of Petroleum and Mining Engineering, Suez University, Suez 43721, Egypt","Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Branch Department of Science and Mathematics, Faculty of Petroleum and Mining Engineering, Suez University, Suez 43721, Egypt","institution_ids":["https://openalex.org/I130009713"]},{"raw_affiliation_string":"Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074565235","display_name":"Tom P Brown","orcid":"https://orcid.org/0000-0002-6538-3036","observed_orcids":["https://orcid.org/0000-0002-6538-3036"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Tom Brown","raw_affiliation_strings":["Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK"],"raw_orcid":"https://orcid.org/0000-0002-6538-3036","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5074565235"],"corresponding_institution_ids":["https://openalex.org/I40120149"],"apc_list":{"value":1600,"currency":"GBP","value_usd":1962},"apc_paid":{"value":1600,"currency":"GBP","value_usd":1962},"fwci":0.3651,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.4348916,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"3","issue":"6","first_page":"765","last_page":"772"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.02449999935925007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.020800000056624413,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pyrene","display_name":"pyrene","score":0.9380000233650208},{"id":"https://openalex.org/keywords/anthraquinones","display_name":"anthraquinones","score":0.9990000128746033},{"id":"https://openalex.org/keywords/rna-duplex-stability","display_name":"RNA duplex stability","score":0.6539999842643738},{"id":"https://openalex.org/keywords/splice-switching","display_name":"splice switching","score":0.7749999761581421},{"id":"https://openalex.org/keywords/ribose-modification","display_name":"ribose modification","score":0.5659999847412109},{"id":"https://openalex.org/keywords/antisense-oligonucleotides","display_name":"antisense oligonucleotides","score":0.8320000171661377}],"concepts":[{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.8392982482910156},{"id":"https://openalex.org/C2777907353","wikidata":"https://www.wikidata.org/wiki/Q903341","display_name":"Triazole","level":2,"score":0.6918786764144897},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6066495776176453},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6035827398300171},{"id":"https://openalex.org/C99611785","wikidata":"https://www.wikidata.org/wiki/Q6453233","display_name":"Duplex (building)","level":3,"score":0.5872158408164978},{"id":"https://openalex.org/C38441620","wikidata":"https://www.wikidata.org/wiki/Q863983","display_name":"Phosphodiester bond","level":4,"score":0.5452802777290344},{"id":"https://openalex.org/C69610077","wikidata":"https://www.wikidata.org/wiki/Q912270","display_name":"Click chemistry","level":2,"score":0.5070879459381104},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.473627507686615},{"id":"https://openalex.org/C180577832","wikidata":"https://www.wikidata.org/wiki/Q127920","display_name":"Covalent bond","level":2,"score":0.46137842535972595},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.43821531534194946},{"id":"https://openalex.org/C186399102","wikidata":"https://www.wikidata.org/wiki/Q903517","display_name":"Chemical stability","level":2,"score":0.43572309613227844},{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.4190075099468231},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.3899194300174713},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34462177753448486},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21525022387504578},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18596595525741577},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.14271366596221924},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10528257489204407}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1039/d2cb00100d","doi":"https://doi.org/10.1039/d2cb00100d","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d2cb00100d","pdf_url":null,"source":{"id":"https://openalex.org/S4210222191","display_name":"RSC Chemical Biology","issn_l":"2633-0679","issn":["2633-0679"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Chemical Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9175110","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9175110/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9175110/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Chem Biol","raw_type":"Text"},{"id":"pmid:35755188","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35755188","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC chemical biology","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.soton.ac.uk:476817","doi":null,"is_oa":false,"landing_page_url":"https://eprints.soton.ac.uk/476817/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:ora.ox.ac.uk:uuid:f9439b25-6b0b-4f6f-bdce-48c7a6d2da5d","doi":null,"is_oa":true,"landing_page_url":"https://ora.ox.ac.uk/objects/uuid:f9439b25-6b0b-4f6f-bdce-48c7a6d2da5d","pdf_url":null,"source":{"id":"https://openalex.org/S4306402636","display_name":"Oxford University Research Archive (ORA) (University of Oxford)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I40120149","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/I40120149"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Symplectic Elements","raw_type":"Journal article"}],"best_oa_location":{"id":"doi:10.1039/d2cb00100d","doi":"https://doi.org/10.1039/d2cb00100d","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d2cb00100d","pdf_url":null,"source":{"id":"https://openalex.org/S4210222191","display_name":"RSC Chemical Biology","issn_l":"2633-0679","issn":["2633-0679"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Chemical Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2068366838","display_name":null,"funder_award_id":"BB/J001694/2","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G2752564131","display_name":"Advancing Oligonucleotide Therapeutics","funder_award_id":"BB/W003902/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G3053607539","display_name":"High-sensitivity multinuclear 600 MHz NMR for synthesis, catalysis and functional materials","funder_award_id":"EP/T019190/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G6063894222","display_name":"New oligonucleotide analogues for therapeutic applications","funder_award_id":"BB/S018794/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G8603737937","display_name":"New and versatile chemical approaches for the synthesis of mRNA and tRNA","funder_award_id":"BB/R008655/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320320290","display_name":"University of Oxford","ror":"https://ror.org/052gg0110"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4283662630.pdf","grobid_xml":"https://content.openalex.org/works/W4283662630.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1967114346","https://openalex.org/W1974044507","https://openalex.org/W1987554430","https://openalex.org/W1987911817","https://openalex.org/W1988001647","https://openalex.org/W1989251809","https://openalex.org/W1994293249","https://openalex.org/W2000133544","https://openalex.org/W2004652357","https://openalex.org/W2009075683","https://openalex.org/W2012278260","https://openalex.org/W2014830700","https://openalex.org/W2020224924","https://openalex.org/W2032305454","https://openalex.org/W2037165791","https://openalex.org/W2038332844","https://openalex.org/W2040135588","https://openalex.org/W2040743013","https://openalex.org/W2050230983","https://openalex.org/W2051010056","https://openalex.org/W2072975221","https://openalex.org/W2077734250","https://openalex.org/W2080660363","https://openalex.org/W2086975669","https://openalex.org/W2090183104","https://openalex.org/W2128926119","https://openalex.org/W2145662716","https://openalex.org/W2145882885","https://openalex.org/W2154134651","https://openalex.org/W2155089348","https://openalex.org/W2169556623","https://openalex.org/W2170561779","https://openalex.org/W2172085519","https://openalex.org/W2286801402","https://openalex.org/W2316132657","https://openalex.org/W2576942864","https://openalex.org/W2592524531","https://openalex.org/W2624035866","https://openalex.org/W2735161949","https://openalex.org/W2741962017","https://openalex.org/W2771247031","https://openalex.org/W2810035754","https://openalex.org/W2895155188","https://openalex.org/W2997283774","https://openalex.org/W3017832738","https://openalex.org/W3131848822","https://openalex.org/W3133563112","https://openalex.org/W3145257564"],"related_works":["https://openalex.org/W2016822283","https://openalex.org/W2908548841","https://openalex.org/W2741962017","https://openalex.org/W2922045180","https://openalex.org/W2810035754","https://openalex.org/W1984152866","https://openalex.org/W1979961879","https://openalex.org/W2336720653","https://openalex.org/W2069185386","https://openalex.org/W1975944271"],"abstract_inverted_index":{"distribution.":[0],"Triazole":[1],"linkages,":[2],"however,":[3],"are":[4],"known":[5],"to":[6,21,34],"reduce":[7],"RNA":[8],"target":[9],"binding":[10],"affinity.":[11],"Here":[12],"we":[13],"show":[14],"that":[15],"by":[16],"attaching":[17],"pyrene":[18],"or":[19],"anthraquinone":[20],"the":[22,26,29,40],"ribose":[23],"sugar":[24],"on":[25],"5'-side":[27],"of":[28,44],"triazole,":[30],"it":[31],"is":[32],"possible":[33],"recover":[35],"duplex":[36],"stability":[37],"and":[38],"restore":[39],"splice":[41],"switching":[42],"ability":[43],"triazole-containing":[45],"oligonucleotides.":[46]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2022-06-29T00:00:00"}