{"id":"https://openalex.org/W4283645909","doi":"https://doi.org/10.3390/pharmaceutics14071359","title":"Ciprofloxacin-Loaded Titanium Nanotubes Coated with Chitosan: A Promising Formulation with Sustained Release and Enhanced Antibacterial Properties","display_name":"Ciprofloxacin-Loaded Titanium Nanotubes Coated with Chitosan: A Promising Formulation with Sustained Release and Enhanced Antibacterial Properties","publication_year":2022,"publication_date":"2022-06-27","ids":{"openalex":"https://openalex.org/W4283645909","doi":"https://doi.org/10.3390/pharmaceutics14071359","pmid":"https://pubmed.ncbi.nlm.nih.gov/35890255","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9316085"},"language":"en","primary_location":{"id":"doi:10.3390/pharmaceutics14071359","doi":"https://doi.org/10.3390/pharmaceutics14071359","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics14071359","pdf_url":"https://www.mdpi.com/1999-4923/14/7/1359/pdf?version=1657089845","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1999-4923/14/7/1359/pdf?version=1657089845","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086017089","display_name":"Soada Asadi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I38476204","display_name":"Urmia University","ror":"https://ror.org/032fk0x53","country_code":"IR","type":"education","lineage":["https://openalex.org/I38476204"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Soada Asadi","raw_affiliation_strings":["Department of Anlytical Chemistry, Faculty of Chemistry, Urmia University, Urmia 5756151818, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anlytical Chemistry, Faculty of Chemistry, Urmia University, Urmia 5756151818, Iran","institution_ids":["https://openalex.org/I38476204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067894739","display_name":"Bardia Mortezagholi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I2801553314","display_name":"Islamic Azad University Dental Branch of Tehran","ror":"https://ror.org/05m5wey82","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I2801553314"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Bardia Mortezagholi","raw_affiliation_strings":["Faculty of Dentistry, Islamic Azad University Tehran Branch, Tehran 1148963537, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Dentistry, Islamic Azad University Tehran Branch, Tehran 1148963537, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I2801553314"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073543331","display_name":"Alireza Hadizadeh","orcid":"https://orcid.org/0000-0003-0821-7557","observed_orcids":["https://orcid.org/0000-0003-0821-7557","https://orcid.org/0000-0002-3595-431X"]},"institutions":[{"id":"https://openalex.org/I4403928369","display_name":"Cardiovascular Diseases Research Institute","ror":"https://ror.org/01ktv1m31","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4401041623","https://openalex.org/I4403928369","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Alireza Hadizadeh","raw_affiliation_strings":["Research Center for Advanced Technologies in Cardiovascular Medicine, Cardiovascular Diseases Research Center Institute, Tehran University of Medical Sciences, Tehran 1419733141, Iran","School of Medicine, Tehran University of Medical Sciences, Tehran 1419733141, Iran"],"raw_orcid":"https://orcid.org/0000-0003-0821-7557","affiliations":[{"raw_affiliation_string":"Research Center for Advanced Technologies in Cardiovascular Medicine, Cardiovascular Diseases Research Center Institute, Tehran University of Medical Sciences, Tehran 1419733141, Iran","institution_ids":["https://openalex.org/I4403928369","https://openalex.org/I70640408"]},{"raw_affiliation_string":"School of Medicine, Tehran University of Medical Sciences, Tehran 1419733141, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015206144","display_name":"Vitaliy Viktorovich Borisov","orcid":"https://orcid.org/0000-0001-6233-0775","observed_orcids":["https://orcid.org/0000-0001-6233-0775"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Vitaliy Borisov","raw_affiliation_strings":["Department of Propaedeutics of Dental Diseases, Sechenov First Moscow State Medical University, 119991 Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Propaedeutics of Dental Diseases, Sechenov First Moscow State Medical University, 119991 Moscow, Russia","institution_ids":["https://openalex.org/I17877952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032847921","display_name":"Mohammad Javed Ansari","orcid":"https://orcid.org/0000-0001-9266-7133","observed_orcids":["https://orcid.org/0000-0001-9266-7133"]},"institutions":[{"id":"https://openalex.org/I142608572","display_name":"Prince Sattam Bin Abdulaziz University","ror":"https://ror.org/04jt46d36","country_code":"SA","type":"education","lineage":["https://openalex.org/I142608572"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Mohammad Javed Ansari","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia"],"raw_orcid":"https://orcid.org/0000-0001-9266-7133","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia","institution_ids":["https://openalex.org/I142608572"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083807668","display_name":"Hasan Sh. Majdi","orcid":"https://orcid.org/0000-0001-6752-4835","observed_orcids":["https://orcid.org/0000-0001-6752-4835"]},"institutions":[{"id":"https://openalex.org/I4400573189","display_name":"Al-Mustaqbal University","ror":"https://ror.org/023a3xe97","country_code":"IQ","type":"education","lineage":["https://openalex.org/I4400573189"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Hasan Shaker Majdi","raw_affiliation_strings":["Department of Chemical Engineering and Petroleum Industries, Al-Mustaqbal University College, Babylon 51001, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Petroleum Industries, Al-Mustaqbal University College, Babylon 51001, Iraq","institution_ids":["https://openalex.org/I4400573189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053167076","display_name":"Azizakhon Nishonova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Azizakhon Nishonova","raw_affiliation_strings":["Department of Physiology and Pathology, Tashkent State Dental Institute, Tashkent 100047, Uzbekistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pathology, Tashkent State Dental Institute, Tashkent 100047, Uzbekistan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054207137","display_name":"Hossein Adelnia","orcid":"https://orcid.org/0000-0002-6124-1460","observed_orcids":["https://orcid.org/0000-0002-6124-1460"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Hossein Adelnia","raw_affiliation_strings":["Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077817757","display_name":"Bahareh Farasati Far","orcid":"https://orcid.org/0000-0002-1598-2487","observed_orcids":["https://orcid.org/0000-0002-1598-2487"]},"institutions":[{"id":"https://openalex.org/I67009956","display_name":"Iran University of Science and Technology","ror":"https://ror.org/01jw2p796","country_code":"IR","type":"education","lineage":["https://openalex.org/I67009956"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Bahareh Farasati Far","raw_affiliation_strings":["Department of Chemistry, Iran University of Science and Technology, Tehran 1684613114, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Iran University of Science and Technology, Tehran 1684613114, Iran","institution_ids":["https://openalex.org/I67009956"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069540900","display_name":"Chaiyavat Chaiyasut","orcid":"https://orcid.org/0000-0002-1633-2419","observed_orcids":["https://orcid.org/0000-0002-1633-2419"]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Chaiyavat Chaiyasut","raw_affiliation_strings":["Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand"],"raw_orcid":"https://orcid.org/0000-0002-1633-2419","affiliations":[{"raw_affiliation_string":"Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand","institution_ids":["https://openalex.org/I48076826"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5069540900","https://openalex.org/A5077817757"],"corresponding_institution_ids":["https://openalex.org/I48076826","https://openalex.org/I67009956"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2513},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2513},"fwci":3.106,"has_fulltext":true,"cited_by_count":54,"citation_normalized_percentile":{"value":0.93674585,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"14","issue":"7","first_page":"1359","last_page":"1359"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12340","display_name":"Anodic Oxide Films and Nanostructures","score":0.739300012588501,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12340","display_name":"Anodic Oxide Films and Nanostructures","score":0.739300012588501,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.14980000257492065,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ciprofloxacin","display_name":"ciprofloxacin","score":0.9490000009536743},{"id":"https://openalex.org/keywords/titanium-nanotubes","display_name":"titanium nanotubes","score":0.9279999732971191},{"id":"https://openalex.org/keywords/anodized-titanium","display_name":"anodized titanium","score":0.7450000047683716},{"id":"https://openalex.org/keywords/chitosan-coating","display_name":"chitosan coating","score":0.9620000123977661},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.9129999876022339},{"id":"https://openalex.org/keywords/antibiotic-delivery","display_name":"antibiotic delivery","score":0.7490000128746033},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.7409999966621399},{"id":"https://openalex.org/keywords/peptostreptococcus","display_name":"Peptostreptococcus","score":0.9070000052452087},{"id":"https://openalex.org/keywords/fusobacterium","display_name":"Fusobacterium","score":1.0},{"id":"https://openalex.org/keywords/endodontic-infection","display_name":"root canal infection","score":0.6299999952316284},{"id":"https://openalex.org/keywords/encapsulation-efficiency","display_name":"encapsulation efficiency","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C2779732960","wikidata":"https://www.wikidata.org/wiki/Q408510","display_name":"Chitosan","level":2,"score":0.8034191131591797},{"id":"https://openalex.org/C2781448156","wikidata":"https://www.wikidata.org/wiki/Q1570182","display_name":"Coating","level":2,"score":0.5577688217163086},{"id":"https://openalex.org/C26771246","wikidata":"https://www.wikidata.org/wiki/Q321095","display_name":"Scanning electron microscope","level":2,"score":0.5302718877792358},{"id":"https://openalex.org/C506065880","wikidata":"https://www.wikidata.org/wiki/Q716","display_name":"Titanium","level":2,"score":0.5001609325408936},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.49492448568344116},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.4795372486114502},{"id":"https://openalex.org/C2778512257","wikidata":"https://www.wikidata.org/wiki/Q256602","display_name":"Ciprofloxacin","level":3,"score":0.4665237367153168},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.44778311252593994},{"id":"https://openalex.org/C3019249092","wikidata":"https://www.wikidata.org/wiki/Q274493","display_name":"Antibacterial agent","level":3,"score":0.43189162015914917},{"id":"https://openalex.org/C22016385","wikidata":"https://www.wikidata.org/wiki/Q567502","display_name":"Anodizing","level":3,"score":0.4311872124671936},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4007170796394348},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2517040967941284},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.2016696333885193},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.14856407046318054},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07478639483451843},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.067586749792099},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.05750057101249695},{"id":"https://openalex.org/C513153333","wikidata":"https://www.wikidata.org/wiki/Q663","display_name":"Aluminium","level":2,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3390/pharmaceutics14071359","doi":"https://doi.org/10.3390/pharmaceutics14071359","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics14071359","pdf_url":"https://www.mdpi.com/1999-4923/14/7/1359/pdf?version=1657089845","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},{"id":"pmid:35890255","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35890255","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9316085","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9316085/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:bd63d48a80554ebe982ffa7242c35852","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bd63d48a80554ebe982ffa7242c35852","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceutics, Vol 14, Iss 7, p 1359 (2022)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/22117307","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Ciprofloxacin-Loaded_Titanium_Nanotubes_Coated_with_Chitosan_A_Promising_Formulation_with_Sustained_Release_and_Enhanced_Antibacterial_Properties/22117307","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"doi:10.6084/m9.figshare.22117307.v1","doi":"https://doi.org/10.6084/m9.figshare.22117307.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.22117307.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.3390/pharmaceutics14071359","doi":"https://doi.org/10.3390/pharmaceutics14071359","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics14071359","pdf_url":"https://www.mdpi.com/1999-4923/14/7/1359/pdf?version=1657089845","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4283645909.pdf","grobid_xml":"https://content.openalex.org/works/W4283645909.grobid-xml"},"referenced_works_count":76,"referenced_works":["https://openalex.org/W1622068987","https://openalex.org/W1979330360","https://openalex.org/W2004091942","https://openalex.org/W2014213112","https://openalex.org/W2022689028","https://openalex.org/W2025845360","https://openalex.org/W2047916544","https://openalex.org/W2047925917","https://openalex.org/W2073809196","https://openalex.org/W2078690504","https://openalex.org/W2088723019","https://openalex.org/W2089372475","https://openalex.org/W2090293337","https://openalex.org/W2095267747","https://openalex.org/W2102878235","https://openalex.org/W2128672939","https://openalex.org/W2165971634","https://openalex.org/W2178861025","https://openalex.org/W2215906863","https://openalex.org/W2294869435","https://openalex.org/W2295778047","https://openalex.org/W2328556032","https://openalex.org/W2334429624","https://openalex.org/W2336646378","https://openalex.org/W2345588669","https://openalex.org/W2415442674","https://openalex.org/W2519195794","https://openalex.org/W2522287896","https://openalex.org/W2575367849","https://openalex.org/W2587005936","https://openalex.org/W2592917363","https://openalex.org/W2768654546","https://openalex.org/W2772198235","https://openalex.org/W2774504255","https://openalex.org/W2792888809","https://openalex.org/W2793383529","https://openalex.org/W2808171724","https://openalex.org/W2809280212","https://openalex.org/W2809798587","https://openalex.org/W2888847793","https://openalex.org/W2890167612","https://openalex.org/W2903271777","https://openalex.org/W2908418786","https://openalex.org/W2912151954","https://openalex.org/W2914625246","https://openalex.org/W2916533985","https://openalex.org/W2940520015","https://openalex.org/W2946962194","https://openalex.org/W2948483356","https://openalex.org/W2973713520","https://openalex.org/W2982292084","https://openalex.org/W2997230033","https://openalex.org/W3005626549","https://openalex.org/W3023467331","https://openalex.org/W3024142632","https://openalex.org/W3036850179","https://openalex.org/W3038052774","https://openalex.org/W3081465942","https://openalex.org/W3113822829","https://openalex.org/W3128001829","https://openalex.org/W3128375450","https://openalex.org/W3131491068","https://openalex.org/W3166477023","https://openalex.org/W3166757467","https://openalex.org/W3195675320","https://openalex.org/W3197264046","https://openalex.org/W3202013962","https://openalex.org/W3203272441","https://openalex.org/W3211055795","https://openalex.org/W3212764798","https://openalex.org/W3214793257","https://openalex.org/W4206934103","https://openalex.org/W4223571323","https://openalex.org/W4229458830","https://openalex.org/W4244489723","https://openalex.org/W4246911342"],"related_works":["https://openalex.org/W3005626549","https://openalex.org/W2336646378","https://openalex.org/W4282980528","https://openalex.org/W7128070790","https://openalex.org/W2896283450","https://openalex.org/W2294869435","https://openalex.org/W2025087655","https://openalex.org/W2090293337","https://openalex.org/W3117804809","https://openalex.org/W2102878235"],"abstract_inverted_index":{"Due":[0],"to":[1,64,79,83,88,115],"their":[2,49],"high":[3,103],"entrapment":[4],"efficiency,":[5],"anodized":[6],"titanium":[7,38],"nanotubes":[8],"(TiO2-NTs)":[9],"are":[10,193],"considered":[11],"effective":[12],"reservoirs":[13,195],"for":[14,180,196],"loading/releasing":[15],"strong":[16],"antibiotics":[17],"whose":[18],"systemic":[19],"administration":[20],"is":[21],"associated":[22],"with":[23,101,111],"diverse":[24],"and":[25,40,46,70,86,137,170,183,199],"severe":[26],"side-effects.":[27],"In":[28,140],"this":[29,188],"study,":[30],"TiO2-NTs":[31,100,192],"were":[32,51,124],"synthesized":[33],"by":[34,109,126],"anodic":[35],"oxidation":[36],"of":[37,43,73,106,158,161,177],"foils,":[39],"the":[41,58,66,74,146,148,152,155,162,181,184,201],"effects":[42],"electrolyte":[44],"percentage":[45],"viscosity":[47],"on":[48],"dimensions":[50],"evaluated.":[52],"It":[53],"was":[54,97],"found":[55],"that":[56,145,191,200],"as":[57,130],"water":[59],"content":[60],"increased":[61],"from":[62,77,168],"15":[63],"30%,":[65],"wall":[67],"thickness,":[68],"length,":[69],"inner":[71],"diameter":[72],"NTs":[75],"increase":[76],"5.9":[78],"15.8":[80],"nm,":[81,90],"1.56":[82],"3.21":[84],"\u00b5m,":[85],"59":[87],"84":[89],"respectively.":[91],"Ciprofloxacin,":[92],"a":[93,102,117,207,213],"highly":[94],"potent":[95],"antibiotic,":[96],"loaded":[98],"into":[99],"encapsulation":[104],"efficiency":[105],"93%,":[107],"followed":[108],"coating":[110,203],"different":[112],"chitosan":[113,149,202],"layers":[114],"achieve":[116],"sustained":[118,154,208],"release":[119,142,209],"profile.":[120],"The":[121],"prepared":[122],"formulations":[123],"characterized":[125],"various":[127],"techniques,":[128],"such":[129],"scanning":[131,135],"electron":[132],"microscopy,":[133],"differential":[134],"calorimetry,":[136],"contact":[138],"measurement.":[139],"vitro":[141],"studies":[143],"showed":[144],"higher":[147],"layer":[150],"count,":[151],"more":[153],"release.":[156],"Evaluation":[157],"antimicrobial":[159],"activity":[160],"formulation":[163],"against":[164],"two":[165],"endodontic":[166],"species":[167],"Peptostreptococcus":[169],"Fusobacterium":[171],"revealed":[172],"minimum":[173],"inhibitory":[174],"concentrations":[175],"(MICs)":[176],"1":[178],"\u00b5g/mL":[179],"former":[182],"latter.":[185],"To":[186],"summarize,":[187],"study":[189],"demonstrated":[190],"promising":[194],"drug":[197],"loading,":[198],"provides":[204],"not":[205],"only":[206],"profile,":[210],"but":[211],"also":[212],"synergistic":[214],"antibacterial":[215],"effect.":[216]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":19},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-06-29T00:00:00"}