{"id":"https://openalex.org/W4283592606","doi":"https://doi.org/10.3389/fonc.2022.905490","title":"A Novel Prognostic Scoring Model for Myelodysplastic Syndrome Patients With SF3B1 Mutation","display_name":"A Novel Prognostic Scoring Model for Myelodysplastic Syndrome Patients With SF3B1 Mutation","publication_year":2022,"publication_date":"2022-06-27","ids":{"openalex":"https://openalex.org/W4283592606","doi":"https://doi.org/10.3389/fonc.2022.905490","pmid":"https://pubmed.ncbi.nlm.nih.gov/35832562","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9271788"},"language":"en","primary_location":{"id":"doi:10.3389/fonc.2022.905490","doi":"https://doi.org/10.3389/fonc.2022.905490","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2022.905490","pdf_url":null,"source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3389/fonc.2022.905490","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002844819","display_name":"Liya Ma","orcid":"https://orcid.org/0000-0001-8428-1791","observed_orcids":["https://orcid.org/0000-0001-8428-1791"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liya Ma","raw_affiliation_strings":["Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bin Liang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146620803","display_name":"Wenzhou University","ror":"https://ror.org/020hxh324","country_code":"CN","type":"education","lineage":["https://openalex.org/I146620803"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Liang","raw_affiliation_strings":["Department of Hematology, The First Affiliated Hospital of Wenzhou University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First Affiliated Hospital of Wenzhou University, Wenzhou, China","institution_ids":["https://openalex.org/I146620803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044490554","display_name":"Huixian Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162045","display_name":"Jinhua Central Hospital","ror":"https://ror.org/04z13ha89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210162045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huixian Hu","raw_affiliation_strings":["Department of Hematology, Jinhua Central Hospital, Jinhua, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Jinhua Central Hospital, Jinhua, China","institution_ids":["https://openalex.org/I4210162045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087046731","display_name":"Wenli Yang","orcid":"https://orcid.org/0000-0002-1873-2336","observed_orcids":["https://orcid.org/0000-0002-1873-2336"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenli Yang","raw_affiliation_strings":["Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100638326","display_name":"Shengyun Lin","orcid":"https://orcid.org/0000-0001-7280-5076","observed_orcids":["https://orcid.org/0000-0001-7280-5076"]},"institutions":[{"id":"https://openalex.org/I4210095527","display_name":"Zhejiang Provincial Hospital of TCM","ror":"https://ror.org/00mzdyq43","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210095527"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengyun Lin","raw_affiliation_strings":["Department of Hematology, Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou, China","institution_ids":["https://openalex.org/I4210095527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080363360","display_name":"Lihong Cao","orcid":"https://orcid.org/0000-0002-7818-9937","observed_orcids":["https://orcid.org/0000-0002-7818-9937"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lihong Cao","raw_affiliation_strings":["Department of Hematology, Shulan Hospital of Zhejiang Province, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Shulan Hospital of Zhejiang Province, Hangzhou, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055452069","display_name":"Kongfei Li","orcid":"https://orcid.org/0000-0001-7938-3224","observed_orcids":["https://orcid.org/0000-0001-7938-3224"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kongfei Li","raw_affiliation_strings":["Department of Hematology, Ningbo Yinzhou People's Hospital, Ningbo, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Ningbo Yinzhou People's Hospital, Ningbo, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006400081","display_name":"Yuemin Kuang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuemin Kuang","raw_affiliation_strings":["Department of Hematology, Jinhua People's Hospital, Jinhua, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Jinhua People's Hospital, Jinhua, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089465933","display_name":"Lihong Shou","orcid":"https://orcid.org/0009-0002-2900-4024","observed_orcids":["https://orcid.org/0009-0002-2900-4024"]},"institutions":[{"id":"https://openalex.org/I4210105567","display_name":"Huzhou Central Hospital","ror":"https://ror.org/01czx1v82","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105567","https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lihong Shou","raw_affiliation_strings":["Department of Hematology, Huzhou Central Hospital, Huzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Huzhou Central Hospital, Huzhou, China","institution_ids":["https://openalex.org/I4210105567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101079882","display_name":"Weimei Jin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125219","display_name":"Lishui City People's Hospital","ror":"https://ror.org/028yz2737","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125219"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weimei Jin","raw_affiliation_strings":["Department of Hematology, Lishui People's Hospital, Lishui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Lishui People's Hospital, Lishui, China","institution_ids":["https://openalex.org/I4210125219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102895201","display_name":"Jianping Lan","orcid":"https://orcid.org/0000-0002-8541-9219","observed_orcids":["https://orcid.org/0000-0002-8541-9219"]},"institutions":[{"id":"https://openalex.org/I4210131061","display_name":"Zhejiang Provincial People's Hospital","ror":"https://ror.org/03k14e164","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131061"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianping Lan","raw_affiliation_strings":["Department of Hematology, Zhejiang Provincial People's Hospital, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Zhejiang Provincial People's Hospital, Hangzhou, China","institution_ids":["https://openalex.org/I4210131061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071724060","display_name":"Xingnong Ye","orcid":"https://orcid.org/0000-0002-2657-6716","observed_orcids":["https://orcid.org/0000-0002-2657-6716"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xingnong Ye","raw_affiliation_strings":["Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China","Department of Hematology, The Fourth Affiliated Hospital of Zhejiang University, Yiwu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210166576"]},{"raw_affiliation_string":"Department of Hematology, The Fourth Affiliated Hospital of Zhejiang University, Yiwu, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jing Le","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113377","display_name":"Ningbo Medical Center Lihuili Hospital","ror":"https://ror.org/030zcqn97","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113377"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Le","raw_affiliation_strings":["Department of Hematology, Ningbo Lihuili Hospital, Ningbo, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Ningbo Lihuili Hospital, Ningbo, China","institution_ids":["https://openalex.org/I4210113377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063619731","display_name":"Huyi Lei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I192209268","display_name":"Shaoxing University","ror":"https://ror.org/0435tej63","country_code":"CN","type":"education","lineage":["https://openalex.org/I192209268"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huyi Lei","raw_affiliation_strings":["Department of Hematology, The Affiliated Hospital of Shaoxing University of Arts and Sciences, Shaoxing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Shaoxing University of Arts and Sciences, Shaoxing, China","institution_ids":["https://openalex.org/I192209268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101148339","display_name":"Jiaping Fu","orcid":"https://orcid.org/0000-0001-5837-6519","observed_orcids":["https://orcid.org/0000-0001-5837-6519"]},"institutions":[{"id":"https://openalex.org/I4210160695","display_name":"Shaoxing People's Hospital","ror":"https://ror.org/05v58y004","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160695"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaping Fu","raw_affiliation_strings":["Department of Hematology, Shaoxing People's Hospital, Shaoxing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Shaoxing People's Hospital, Shaoxing, China","institution_ids":["https://openalex.org/I4210160695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055831532","display_name":"Ying Lin","orcid":"https://orcid.org/0009-0008-2891-7984","observed_orcids":["https://orcid.org/0009-0008-2891-7984"]},"institutions":[{"id":"https://openalex.org/I146620803","display_name":"Wenzhou University","ror":"https://ror.org/020hxh324","country_code":"CN","type":"education","lineage":["https://openalex.org/I146620803"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Lin","raw_affiliation_strings":["Department of Hematology, The Second Affiliated Hospital of Wenzhou University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The Second Affiliated Hospital of Wenzhou University, Wenzhou, China","institution_ids":["https://openalex.org/I146620803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101970672","display_name":"Wenhua Jiang","orcid":"https://orcid.org/0000-0002-6252-6732","observed_orcids":["https://orcid.org/0000-0002-6252-6732"]},"institutions":[{"id":"https://openalex.org/I4210143819","display_name":"Taizhou First People's Hospital","ror":"https://ror.org/04jyt7608","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143819"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenhua Jiang","raw_affiliation_strings":["Department of Hematology, Taizhou First People's Hospital, Taizhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Taizhou First People's Hospital, Taizhou, China","institution_ids":["https://openalex.org/I4210143819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101185529","display_name":"Zhiying Zheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095527","display_name":"Zhejiang Provincial Hospital of TCM","ror":"https://ror.org/00mzdyq43","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210095527"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiying Zheng","raw_affiliation_strings":["Department of Hematology, Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou, China","institution_ids":["https://openalex.org/I4210095527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046001715","display_name":"Songfu Jiang","orcid":"https://orcid.org/0000-0002-2039-4233","observed_orcids":["https://orcid.org/0000-0002-2039-4233","https://orcid.org/0000-0002-1458-1753"]},"institutions":[{"id":"https://openalex.org/I146620803","display_name":"Wenzhou University","ror":"https://ror.org/020hxh324","country_code":"CN","type":"education","lineage":["https://openalex.org/I146620803"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Songfu Jiang","raw_affiliation_strings":["Department of Hematology, The First Affiliated Hospital of Wenzhou University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First Affiliated Hospital of Wenzhou University, Wenzhou, China","institution_ids":["https://openalex.org/I146620803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102990340","display_name":"Lijuan Fu","orcid":"https://orcid.org/0000-0002-6154-3944","observed_orcids":["https://orcid.org/0000-0002-6154-3944"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lijuan Fu","raw_affiliation_strings":["Department of Hematology, Xinhua Hospital of Zhejiang Province, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Xinhua Hospital of Zhejiang Province, Hangzhou, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026591783","display_name":"Chuanyong Su","orcid":"https://orcid.org/0000-0002-6984-2666","observed_orcids":["https://orcid.org/0000-0002-6984-2666"]},"institutions":[{"id":"https://openalex.org/I4210097783","display_name":"Tongde Hospital of Zhejiang Province","ror":"https://ror.org/00trnhw76","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097783"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chuanyong Su","raw_affiliation_strings":["Department of Hematology, Tongde Hospital of Zhejiang Province, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Tongde Hospital of Zhejiang Province, Hangzhou, China","institution_ids":["https://openalex.org/I4210097783"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108587945","display_name":"Xiufeng Yin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"XiuFeng Yin","raw_affiliation_strings":["Department of Hematology, The Affiliated Shaoyifu Hospital of Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The Affiliated Shaoyifu Hospital of Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104083785","display_name":"Lixia Liu","orcid":"https://orcid.org/0009-0000-7766-0195","observed_orcids":["https://orcid.org/0009-0000-7766-0195"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lixia Liu","raw_affiliation_strings":["Department of Medical Affairs, Acornmed Biotechnology Co., Ltd., Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Affairs, Acornmed Biotechnology Co., Ltd., Tianjin, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001738573","display_name":"Jiayue Qin","orcid":"https://orcid.org/0000-0003-4721-0016","observed_orcids":["https://orcid.org/0000-0003-4721-0016"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jiayue Qin","raw_affiliation_strings":["Department of Medical Affairs, Acornmed Biotechnology Co., Ltd., Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Affairs, Acornmed Biotechnology Co., Ltd., Tianjin, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000239300","display_name":"Jie Jin","orcid":"https://orcid.org/0000-0002-8166-9915","observed_orcids":["https://orcid.org/0000-0002-8166-9915"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Jin","raw_affiliation_strings":["Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044547848","display_name":"Shenxian Qian","orcid":"https://orcid.org/0000-0002-6844-7277","observed_orcids":["https://orcid.org/0000-0002-6844-7277","https://orcid.org/0000-0003-1026-4395","https://orcid.org/0009-0009-3431-7448","https://orcid.org/0000-0001-6763-0822"]},"institutions":[{"id":"https://openalex.org/I4210148790","display_name":"Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine","ror":"https://ror.org/05pwsw714","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210148790"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shenxian Qian","raw_affiliation_strings":["Department of Hematology, Hangzhou First People's Hospital, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Hangzhou First People's Hospital, Hangzhou, China","institution_ids":["https://openalex.org/I4210148790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080969569","display_name":"Guifang Ouyang","orcid":"https://orcid.org/0000-0002-3411-3666","observed_orcids":["https://orcid.org/0000-0002-3411-3666"]},"institutions":[{"id":"https://openalex.org/I4210166261","display_name":"Ningbo First Hospital","ror":"https://ror.org/05pkzpg75","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166261"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guifang Ouyang","raw_affiliation_strings":["Department of Hematology, Ningbo First Hospital, Ningbo, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Ningbo First Hospital, Ningbo, China","institution_ids":["https://openalex.org/I4210166261"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033050924","display_name":"Hongyan Tong","orcid":"https://orcid.org/0000-0001-5603-4160","observed_orcids":["https://orcid.org/0000-0001-5603-4160"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hongyan Tong","raw_affiliation_strings":["Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First Affiliated Hospital of Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I4210166576"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5033050924","https://openalex.org/A5044547848","https://openalex.org/A5080969569"],"corresponding_institution_ids":["https://openalex.org/I4210148790","https://openalex.org/I4210166261","https://openalex.org/I4210166576"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.3585,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.58422002,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"12","issue":null,"first_page":"905490","last_page":"905490"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myelodysplastic-syndrome","display_name":"myelodysplastic syndrome","score":1.0},{"id":"https://openalex.org/keywords/sf3b1-mutation","display_name":"SF3B1 mutation","score":1.0},{"id":"https://openalex.org/keywords/prognostic-score","display_name":"prognostic score","score":0.9769999980926514},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.746999979019165},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8149999976158142},{"id":"https://openalex.org/keywords/ring-sideroblasts","display_name":"ring sideroblasts","score":0.7919999957084656},{"id":"https://openalex.org/keywords/ipss-r","display_name":"IPSS-R","score":0.781000018119812},{"id":"https://openalex.org/keywords/runx1","display_name":"RUNX1","score":0.8479999899864197},{"id":"https://openalex.org/keywords/ezh2","display_name":"EZH2","score":1.0},{"id":"https://openalex.org/keywords/neurofibromatosis-type-1","display_name":"neurofibromatosis type 1","score":0.703000009059906},{"id":"https://openalex.org/keywords/clonal-hematopoiesis","display_name":"clonal hematopoiesis","score":0.7480000257492065},{"id":"https://openalex.org/keywords/personalized-prediction-models","display_name":"personalized prediction models","score":0.4269999861717224}],"concepts":[{"id":"https://openalex.org/C2780240888","wikidata":"https://www.wikidata.org/wiki/Q6052586","display_name":"International Prognostic Scoring System","level":4,"score":0.8656015396118164},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7585912942886353},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7323182225227356},{"id":"https://openalex.org/C21790070","wikidata":"https://www.wikidata.org/wiki/Q18030215","display_name":"Neuroblastoma RAS viral oncogene homolog","level":5,"score":0.5997768044471741},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.595477819442749},{"id":"https://openalex.org/C2781187634","wikidata":"https://www.wikidata.org/wiki/Q20969980","display_name":"KRAS","level":4,"score":0.5439798831939697},{"id":"https://openalex.org/C2780817109","wikidata":"https://www.wikidata.org/wiki/Q954625","display_name":"Myelodysplastic syndromes","level":3,"score":0.5116755962371826},{"id":"https://openalex.org/C2994225774","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Gene mutation","level":4,"score":0.43435773253440857},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.42708539962768555},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23548811674118042},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.20218464732170105},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.1175219714641571},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09448736906051636},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08321031928062439},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fonc.2022.905490","doi":"https://doi.org/10.3389/fonc.2022.905490","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2022.905490","pdf_url":null,"source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9271788","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9271788","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Oncol","raw_type":"Text"},{"id":"pmid:35832562","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35832562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in oncology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:0027be8f33ee4b47aaabec93143fea60","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/0027be8f33ee4b47aaabec93143fea60","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Oncology, Vol 12 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fonc.2022.905490","doi":"https://doi.org/10.3389/fonc.2022.905490","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fonc.2022.905490","pdf_url":null,"source":{"id":"https://openalex.org/S2596394214","display_name":"Frontiers in Oncology","issn_l":"2234-943X","issn":["2234-943X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1489375841","https://openalex.org/W1889574318","https://openalex.org/W1963736125","https://openalex.org/W1974555941","https://openalex.org/W1993236149","https://openalex.org/W2005150790","https://openalex.org/W2026134786","https://openalex.org/W2073889874","https://openalex.org/W2083427504","https://openalex.org/W2086974150","https://openalex.org/W2094395093","https://openalex.org/W2101087555","https://openalex.org/W2123355582","https://openalex.org/W2140419897","https://openalex.org/W2144892629","https://openalex.org/W2147370638","https://openalex.org/W2150371267","https://openalex.org/W2151199601","https://openalex.org/W2159249303","https://openalex.org/W2193225046","https://openalex.org/W2264873876","https://openalex.org/W2326726820","https://openalex.org/W2338495337","https://openalex.org/W2413340136","https://openalex.org/W2520178460","https://openalex.org/W2900075143","https://openalex.org/W3005835389","https://openalex.org/W3017704884","https://openalex.org/W3136768428","https://openalex.org/W3164990782","https://openalex.org/W3176968044","https://openalex.org/W4200418764","https://openalex.org/W4252225072"],"related_works":["https://openalex.org/W2590815829","https://openalex.org/W4293763612","https://openalex.org/W3127754785","https://openalex.org/W4392557076","https://openalex.org/W2750378577","https://openalex.org/W2747059835","https://openalex.org/W2769289708","https://openalex.org/W2992438210","https://openalex.org/W2140419897","https://openalex.org/W2887576143"],"abstract_inverted_index":{"The":[0,137],"outcomes":[1],"of":[2,39,177,189],"myelodysplastic":[3],"syndrome":[4],"(MDS)":[5],"patients":[6,32,43,62,179],"with":[7,33,47,180],"SF3B1":[8,34,181],"mutation,":[9],"despite":[10],"identified":[11],"as":[12,45,115],"a":[13,111,173],"favorable":[14],"prognostic":[15],"biomarker,":[16],"are":[17],"variable.":[18],"To":[19],"comprehend":[20],"the":[21,52,68,85,141,163,187],"heterogeneity":[22],"in":[23,36,90],"clinical":[24],"characteristics":[25],"and":[26,59,82,96,129,143,151,171],"outcomes,":[27],"we":[28,109,169],"reviewed":[29],"140":[30],"MDS":[31,46,178],"mutation":[35,182],"Zhejiang":[37],"province":[38],"China.":[40],"Seventy-three":[41],"(52.1%)":[42],"diagnosed":[44],"ring":[48],"sideroblasts":[49],"(MDS-RS)":[50],"following":[51,67],"2016":[53],"World":[54],"Health":[55],"Organization":[56],"(WHO)":[57],"classification":[58],"118":[60],"(84.3%)":[61],"belonged":[63],"to":[64],"lower":[65],"risk":[66,112,131],"revised":[69],"International":[70],"Prognostic":[71],"Scoring":[72],"System":[73],"(IPSS-R).":[74],"Although":[75],"clonal":[76],"hematopoiesis-associated":[77],"mutations":[78,98],"containing":[79],"TET2,":[80],"ASXL1":[81],"DNMT3A":[83],"were":[84,118],"most":[86],"frequent":[87],"co-mutant":[88],"genes":[89],"these":[91,190],"patients,":[92],"RUNX1,":[93],"EZH2,":[94],"NF1":[95],"KRAS/NRAS":[97],"had":[99],"significant":[100],"effects":[101],"on":[102,107],"overall":[103],"survival":[104,188],"(OS).":[105],"Based":[106],"that":[108,183],"developed":[110],"scoring":[113],"model":[114,160,176],"IPSS-R\u00d70.4+RUNX1\u00d71.1+EZH2\u00d70.6+RAS\u00d70.9+NF1\u00d71.6.":[116],"Patients":[117],"categorized":[119],"into":[120],"two":[121],"subgroups:":[122],"low-risk":[123],"(L-R,":[124],"score":[125,133],"<=":[126],"1.4)":[127,135],"group":[128],"high":[130],"(H-R,":[132],">":[134],"group.":[136],"3-year":[138],"OS":[139],"for":[140],"L-R":[142],"H-R":[144],"groups":[145],"was":[146],"91.88%":[147],"(95%":[148,153],"CI,":[149,154],"83.27%-100%)":[150],"38.14%":[152],"24.08%-60.40%),":[155],"respectively":[156],"(P<0.001).":[157],"This":[158],"proposed":[159],"distinctly":[161],"outperformed":[162],"widely":[164],"used":[165],"IPSS-R.":[166],"In":[167],"summary,":[168],"constructed":[170],"validated":[172],"personalized":[174],"prediction":[175],"can":[184],"better":[185],"predict":[186],"patients.":[191]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-06-28T00:00:00"}