{"id":"https://openalex.org/W4283399485","doi":"https://doi.org/10.1016/j.snb.2022.132269","title":"Ultrasensitive sensing of T4 PNK phosphatase activity through establishing a novel transcription-based signal amplification platform","display_name":"Ultrasensitive sensing of T4 PNK phosphatase activity through establishing a novel transcription-based signal amplification platform","publication_year":2022,"publication_date":"2022-06-24","ids":{"openalex":"https://openalex.org/W4283399485","doi":"https://doi.org/10.1016/j.snb.2022.132269"},"language":"en","primary_location":{"id":"doi:10.1016/j.snb.2022.132269","doi":"https://doi.org/10.1016/j.snb.2022.132269","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.snb.2022.132269","pdf_url":null,"source":{"id":"https://openalex.org/S98455728","display_name":"Sensors and Actuators B Chemical","issn_l":"0925-4005","issn":["0925-4005","1873-3077"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors and Actuators B: Chemical","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112914370","display_name":"Ran Luo","orcid":"https://orcid.org/0009-0000-7967-6545","observed_orcids":["https://orcid.org/0009-0000-7967-6545"]},"institutions":[{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ran Luo","raw_affiliation_strings":["School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China","institution_ids":["https://openalex.org/I162868743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050151020","display_name":"Guowei Lian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guowei Lian","raw_affiliation_strings":["School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China","institution_ids":["https://openalex.org/I162868743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011233549","display_name":"Hengxuan Li","orcid":"https://orcid.org/0009-0002-9422-746X","observed_orcids":["https://orcid.org/0009-0002-9422-746X","https://orcid.org/0000-0003-1090-5711"]},"institutions":[{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hengxuan Li","raw_affiliation_strings":["School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China","institution_ids":["https://openalex.org/I162868743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021589013","display_name":"Houyu Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Houyu Han","raw_affiliation_strings":["School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China","institution_ids":["https://openalex.org/I162868743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073654909","display_name":"Dianming Zhou","orcid":"https://orcid.org/0000-0002-6532-0975","observed_orcids":["https://orcid.org/0000-0002-6532-0975"]},"institutions":[{"id":"https://openalex.org/I4210102609","display_name":"Tianjin Centers for Disease Control and Prevention","ror":"https://ror.org/01h547a76","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210102609"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dianming Zhou","raw_affiliation_strings":["Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China","institution_ids":["https://openalex.org/I4210102609"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083999985","display_name":"Xiaoqun Gong","orcid":"https://orcid.org/0000-0002-0481-9756","observed_orcids":["https://orcid.org/0000-0002-0481-9756","https://orcid.org/0000-0002-0493-7517"]},"institutions":[{"id":"https://openalex.org/I162868743","display_name":"Tianjin University","ror":"https://ror.org/012tb2g32","country_code":"CN","type":"education","lineage":["https://openalex.org/I162868743"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoqun Gong","raw_affiliation_strings":["School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China","institution_ids":["https://openalex.org/I162868743"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5073654909","https://openalex.org/A5083999985"],"corresponding_institution_ids":["https://openalex.org/I162868743","https://openalex.org/I4210102609"],"apc_list":{"value":4370,"currency":"USD","value_usd":4370},"apc_paid":null,"fwci":0.5111,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.51584379,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"369","issue":null,"first_page":"132269","last_page":"132269"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/t4-polynucleotide-kinase","display_name":"T4 polynucleotide kinase","score":0.9120000004768372},{"id":"https://openalex.org/keywords/cell-free-transcription-system","display_name":"cell-free transcription system","score":0.7839999794960022},{"id":"https://openalex.org/keywords/ultrasensitive-nucleic-acid-detection","display_name":"ultrasensitive nucleic acid detection","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.6755459904670715},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.5859190821647644},{"id":"https://openalex.org/C178666793","wikidata":"https://www.wikidata.org/wiki/Q422476","display_name":"Phosphatase","level":3,"score":0.43852806091308594},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4287121593952179},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42111819982528687},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.4174952805042267},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40067243576049805},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40011584758758545},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3764212131500244},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.33548861742019653},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.25709474086761475},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09775179624557495},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.0895700454711914},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.06663784384727478},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.snb.2022.132269","doi":"https://doi.org/10.1016/j.snb.2022.132269","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.snb.2022.132269","pdf_url":null,"source":{"id":"https://openalex.org/S98455728","display_name":"Sensors and Actuators B Chemical","issn_l":"0925-4005","issn":["0925-4005","1873-3077"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sensors and Actuators B: Chemical","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1672357601","display_name":null,"funder_award_id":"21705118","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5593473919","display_name":null,"funder_award_id":"19ZXDBSY00070","funder_id":"https://openalex.org/F4320323993","funder_display_name":"Natural Science Foundation of Tianjin City"},{"id":"https://openalex.org/G6589978839","display_name":null,"funder_award_id":"20YFZCSY00990","funder_id":"https://openalex.org/F4320323993","funder_display_name":"Natural Science Foundation of Tianjin City"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323993","display_name":"Natural Science Foundation of Tianjin City","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W81209440","https://openalex.org/W1510874233","https://openalex.org/W1967104806","https://openalex.org/W1974518329","https://openalex.org/W1975666473","https://openalex.org/W2003470745","https://openalex.org/W2009584671","https://openalex.org/W2013175404","https://openalex.org/W2014326137","https://openalex.org/W2017139765","https://openalex.org/W2027001273","https://openalex.org/W2063165751","https://openalex.org/W2071452131","https://openalex.org/W2071829817","https://openalex.org/W2077300582","https://openalex.org/W2085272777","https://openalex.org/W2088850938","https://openalex.org/W2093950640","https://openalex.org/W2114940529","https://openalex.org/W2116348850","https://openalex.org/W2123248953","https://openalex.org/W2142871601","https://openalex.org/W2143235709","https://openalex.org/W2143632878","https://openalex.org/W2145038090","https://openalex.org/W2145303234","https://openalex.org/W2149962722","https://openalex.org/W2158654777","https://openalex.org/W2168208027","https://openalex.org/W2316744790","https://openalex.org/W2325534636","https://openalex.org/W2624547014","https://openalex.org/W2767538197","https://openalex.org/W2894587069","https://openalex.org/W2895776296","https://openalex.org/W2912230135","https://openalex.org/W2916420109","https://openalex.org/W2949118389","https://openalex.org/W2998639792","https://openalex.org/W3012751338","https://openalex.org/W3082988112","https://openalex.org/W3087583316","https://openalex.org/W3092322536","https://openalex.org/W3161763201","https://openalex.org/W3178661607","https://openalex.org/W3193569631","https://openalex.org/W3194257545","https://openalex.org/W4231299834"],"related_works":["https://openalex.org/W4304889285","https://openalex.org/W4296222749","https://openalex.org/W2089027336","https://openalex.org/W433267871","https://openalex.org/W4299804919","https://openalex.org/W3203254239","https://openalex.org/W4292059752","https://openalex.org/W3016207605","https://openalex.org/W2292670018","https://openalex.org/W3112640323"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2022-06-25T00:00:00"}