{"id":"https://openalex.org/W4283377976","doi":"https://doi.org/10.1016/j.stemcr.2022.05.020","title":"Aberrant nucleosome organization in mouse SCNT embryos revealed by ULI-MNase-seq","display_name":"Aberrant nucleosome organization in mouse SCNT embryos revealed by ULI-MNase-seq","publication_year":2022,"publication_date":"2022-06-23","ids":{"openalex":"https://openalex.org/W4283377976","doi":"https://doi.org/10.1016/j.stemcr.2022.05.020","pmid":"https://pubmed.ncbi.nlm.nih.gov/35750045","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9287678"},"language":"en","primary_location":{"id":"doi:10.1016/j.stemcr.2022.05.020","doi":"https://doi.org/10.1016/j.stemcr.2022.05.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stemcr.2022.05.020","pdf_url":null,"source":{"id":"https://openalex.org/S2764425922","display_name":"Stem Cell Reports","issn_l":"2213-6711","issn":["2213-6711"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.stemcr.2022.05.020","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028069456","display_name":"Lingyue Yang","orcid":"https://orcid.org/0009-0003-1678-8058","observed_orcids":["https://orcid.org/0009-0003-1678-8058"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210128175","display_name":"Shanghai East Hospital","ror":"https://ror.org/038xmzj21","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128175"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingyue Yang","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074899069","display_name":"Xiaocui Xu","orcid":"https://orcid.org/0000-0003-2488-3664","observed_orcids":["https://orcid.org/0000-0003-2488-3664"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210128175","display_name":"Shanghai East Hospital","ror":"https://ror.org/038xmzj21","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128175"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaocui Xu","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077283838","display_name":"Ruimin Xu","orcid":"https://orcid.org/0000-0002-8746-6350","observed_orcids":["https://orcid.org/0000-0002-8746-6350"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210128175","display_name":"Shanghai East Hospital","ror":"https://ror.org/038xmzj21","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128175"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruimin Xu","raw_affiliation_strings":["Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100429123","display_name":"Chuan Chen","orcid":"https://orcid.org/0000-0001-5701-0857","observed_orcids":["https://orcid.org/0000-0001-5701-0857"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chuan Chen","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100450096","display_name":"Xiaolei Zhang","orcid":"https://orcid.org/0000-0002-0527-7530","observed_orcids":["https://orcid.org/0000-0002-0527-7530"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210128175","display_name":"Shanghai East Hospital","ror":"https://ror.org/038xmzj21","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128175"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaolei Zhang","raw_affiliation_strings":["Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100387252","display_name":"Mo Chen","orcid":"https://orcid.org/0000-0002-6647-8483","observed_orcids":["https://orcid.org/0000-0002-6647-8483","https://orcid.org/0000-0002-3274-5889"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mo Chen","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090920925","display_name":"Xiaochen Kou","orcid":"https://orcid.org/0009-0007-9137-8373","observed_orcids":["https://orcid.org/0009-0007-9137-8373"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaochen Kou","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072862253","display_name":"Yanhong Zhao","orcid":"https://orcid.org/0000-0002-1216-8420","observed_orcids":["https://orcid.org/0000-0002-1216-8420"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanhong Zhao","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100370968","display_name":"Hong Wang","orcid":"https://orcid.org/0000-0003-0212-5379","observed_orcids":["https://orcid.org/0000-0003-0212-5379"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Wang","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100455482","display_name":"Xiaoyu Liu","orcid":"https://orcid.org/0000-0001-6622-9316","observed_orcids":["https://orcid.org/0000-0001-6622-9316"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210128175","display_name":"Shanghai East Hospital","ror":"https://ror.org/038xmzj21","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128175"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoyu Liu","raw_affiliation_strings":["Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China. Electronic address: liuxiaoyu@tongji.edu.cn","Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China. Electronic address: liuxiaoyu@tongji.edu.cn","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175"]},{"raw_affiliation_string":"Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058603003","display_name":"Shaorong Gao","orcid":"https://orcid.org/0000-0003-1041-3928","observed_orcids":["https://orcid.org/0000-0003-1041-3928"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210128175","display_name":"Shanghai East Hospital","ror":"https://ror.org/038xmzj21","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128175"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shaorong Gao","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China. Electronic address: gaoshaorong@tongji.edu.cn","Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China"],"raw_orcid":"https://orcid.org/0000-0003-1041-3928","affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China; Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China. Electronic address: gaoshaorong@tongji.edu.cn","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100424933","display_name":"Chong Li","orcid":"https://orcid.org/0000-0002-2862-1357","observed_orcids":["https://orcid.org/0000-0002-2862-1357"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chong Li","raw_affiliation_strings":["Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China. Electronic address: lichong@tongji.edu.cn","Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China. Electronic address: lichong@tongji.edu.cn","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Clinical and Translation Research Center of Shanghai First Maternity & Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5058603003","https://openalex.org/A5100424933","https://openalex.org/A5100455482"],"corresponding_institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210128175","https://openalex.org/I4210153623"],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":{"value":3800,"currency":"USD","value_usd":3800},"fwci":0.3651,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.4348916,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"17","issue":"7","first_page":"1730","last_page":"1742"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.7056000232696533,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.7056000232696533,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.17499999701976776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.08810000121593475,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/somatic-cell-nuclear-transfer","display_name":"somatic cell nuclear transfer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nucleosome-positioning","display_name":"nucleosome positioning","score":0.9369999766349792},{"id":"https://openalex.org/keywords/nucleosome-depleted-regions","display_name":"nucleosome-depleted regions","score":0.9049999713897705},{"id":"https://openalex.org/keywords/promoter","display_name":"promoter","score":0.49399998784065247},{"id":"https://openalex.org/keywords/epigenetic-reprogramming","display_name":"epigenetic reprogramming","score":0.7419999837875366},{"id":"https://openalex.org/keywords/histone-acetylation","display_name":"histone acetylation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/inner-cell-mass","display_name":"inner cell mass","score":0.8069999814033508},{"id":"https://openalex.org/keywords/preimplantation-embryo-development","display_name":"preimplantation embryo development","score":0.8989999890327454},{"id":"https://openalex.org/keywords/mouse-embryo","display_name":"mouse embryo","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C202438428","wikidata":"https://www.wikidata.org/wiki/Q1939923","display_name":"Somatic cell nuclear transfer","level":5,"score":0.9345135688781738},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8005670309066772},{"id":"https://openalex.org/C84772758","wikidata":"https://www.wikidata.org/wiki/Q271794","display_name":"Nucleosome","level":4,"score":0.7535908222198486},{"id":"https://openalex.org/C2910790502","wikidata":"https://www.wikidata.org/wiki/Q862600","display_name":"Totipotent","level":4,"score":0.630588948726654},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6222165822982788},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6203227043151855},{"id":"https://openalex.org/C77255625","wikidata":"https://www.wikidata.org/wiki/Q402093","display_name":"Reprogramming","level":3,"score":0.6152099967002869},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.4903697967529297},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.4745795726776123},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.47029420733451843},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.4585573077201843},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.4167296588420868},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2940516471862793},{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.2345810830593109},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.2055651843547821}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001755","descriptor_name":"Blastocyst","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053652","descriptor_name":"Nuclear Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.stemcr.2022.05.020","doi":"https://doi.org/10.1016/j.stemcr.2022.05.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stemcr.2022.05.020","pdf_url":null,"source":{"id":"https://openalex.org/S2764425922","display_name":"Stem Cell Reports","issn_l":"2213-6711","issn":["2213-6711"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9287678","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9287678/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9287678/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Reports","raw_type":"Text"},{"id":"pmid:35750045","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35750045","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem cell reports","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.stemcr.2022.05.020","doi":"https://doi.org/10.1016/j.stemcr.2022.05.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stemcr.2022.05.020","pdf_url":null,"source":{"id":"https://openalex.org/S2764425922","display_name":"Stem Cell Reports","issn_l":"2213-6711","issn":["2213-6711"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G147405071","display_name":null,"funder_award_id":"2020YFA0112500","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G2191819384","display_name":null,"funder_award_id":"2021YFA1102900","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G3075916825","display_name":null,"funder_award_id":"2021SHZDZX0100","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G402928388","display_name":null,"funder_award_id":"31721003","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G413896364","display_name":null,"funder_award_id":"31721003","funder_id":"https://openalex.org/F4320327803","funder_display_name":"Shanghai Rising-Star Program"},{"id":"https://openalex.org/G452157749","display_name":null,"funder_award_id":"32100645","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4606321376","display_name":null,"funder_award_id":"2021SHZDZX0100","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4899075050","display_name":null,"funder_award_id":"32070802","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5669343439","display_name":null,"funder_award_id":"32000418","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5827639266","display_name":null,"funder_award_id":"2020M681383","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G612452264","display_name":null,"funder_award_id":"31721003","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G6320009932","display_name":null,"funder_award_id":"20QA409700","funder_id":"https://openalex.org/F4320327803","funder_display_name":"Shanghai Rising-Star Program"},{"id":"https://openalex.org/G6336737326","display_name":null,"funder_award_id":"2021M692437","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G6450733699","display_name":null,"funder_award_id":"2021SHZDZX0100","funder_id":"https://openalex.org/F4320327803","funder_display_name":"Shanghai Rising-Star Program"},{"id":"https://openalex.org/G7406918858","display_name":null,"funder_award_id":"31820103009","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G746818793","display_name":"\u5e72\u7ec6\u80de\u8870\u8001\u7684\u8868\u89c2\u9057\u4f20\u8c03\u63a7\u673a\u5236","funder_award_id":"21JC1405500","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G8111733239","display_name":null,"funder_award_id":"2021SHZDZX0100","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G8844685388","display_name":null,"funder_award_id":"2021SHZDZX0100","funder_id":"https://openalex.org/F4320322449","funder_display_name":"Tongji University"},{"id":"https://openalex.org/G897182718","display_name":null,"funder_award_id":"2021SHZDZX0100","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G922987064","display_name":null,"funder_award_id":"19JC1415300","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321540","display_name":"Ministry of Science and Technology of the People's Republic of China","ror":"https://ror.org/027s68j25"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"},{"id":"https://openalex.org/F4320322449","display_name":"Tongji University","ror":"https://ror.org/03rc6as71"},{"id":"https://openalex.org/F4320327803","display_name":"Shanghai Rising-Star Program","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4283377976.pdf","grobid_xml":"https://content.openalex.org/works/W4283377976.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W1487014009","https://openalex.org/W1974353685","https://openalex.org/W1983159345","https://openalex.org/W1991045672","https://openalex.org/W1992525863","https://openalex.org/W1996270170","https://openalex.org/W1997100349","https://openalex.org/W2006680614","https://openalex.org/W2010765881","https://openalex.org/W2013571070","https://openalex.org/W2025708369","https://openalex.org/W2027669322","https://openalex.org/W2029873987","https://openalex.org/W2050298575","https://openalex.org/W2050608300","https://openalex.org/W2060289784","https://openalex.org/W2061111901","https://openalex.org/W2061184843","https://openalex.org/W2072872182","https://openalex.org/W2076962741","https://openalex.org/W2093155802","https://openalex.org/W2094998522","https://openalex.org/W2099888659","https://openalex.org/W2102136017","https://openalex.org/W2110312780","https://openalex.org/W2117009494","https://openalex.org/W2122097157","https://openalex.org/W2122848810","https://openalex.org/W2129530584","https://openalex.org/W2144792857","https://openalex.org/W2146631202","https://openalex.org/W2151372165","https://openalex.org/W2153824299","https://openalex.org/W2157944902","https://openalex.org/W2163798466","https://openalex.org/W2171605297","https://openalex.org/W2193291380","https://openalex.org/W2289143112","https://openalex.org/W2295180956","https://openalex.org/W2321385422","https://openalex.org/W2413268016","https://openalex.org/W2443585466","https://openalex.org/W2519280707","https://openalex.org/W2729651443","https://openalex.org/W2795625769","https://openalex.org/W2883992623","https://openalex.org/W2888462525","https://openalex.org/W2951091094","https://openalex.org/W2990009305","https://openalex.org/W3015686080","https://openalex.org/W3023847695","https://openalex.org/W3036696453","https://openalex.org/W3043994159","https://openalex.org/W3092364740","https://openalex.org/W3108711013","https://openalex.org/W3194665116","https://openalex.org/W3211014030","https://openalex.org/W4224107018"],"related_works":["https://openalex.org/W2729651443","https://openalex.org/W4411863652","https://openalex.org/W3015686080","https://openalex.org/W2888462525","https://openalex.org/W2773955340","https://openalex.org/W4416337896","https://openalex.org/W2803372704","https://openalex.org/W3082236642","https://openalex.org/W2117009494","https://openalex.org/W2198512942"],"abstract_inverted_index":{"Somatic":[0],"cell":[1,67,93],"nuclear":[2],"transfer":[3],"(SCNT)":[4],"can":[5],"reprogram":[6],"terminally":[7],"differentiated":[8],"somatic":[9],"cells":[10,115,133],"into":[11,146],"totipotent":[12],"embryos,":[13],"but":[14],"with":[15,65,99,136],"multiple":[16],"defects.":[17],"The":[18],"nucleosome":[19,40,71,111,147],"positioning,":[20],"as":[21],"an":[22],"important":[23],"epigenetic":[24],"regulator":[25],"for":[26,120],"gene":[27,88],"expression,":[28],"is":[29,63],"largely":[30],"unexplored":[31],"during":[32,149],"SCNT":[33,44,74,150],"embryonic":[34,152],"development.":[35,153],"Here,":[36],"we":[37,83],"mapped":[38],"genome-wide":[39],"profiles":[41],"in":[42,73,91,102,113],"mouse":[43],"embryos":[45,75],"using":[46],"ultra-low-input":[47],"MNase-seq":[48],"(ULI-MNase-seq).":[49],"We":[50,123],"found":[51,84],"that":[52,85,107,126],"the":[53,66,86,108,127,137],"nucleosome-depleted":[54],"regions":[55],"(NDRs)":[56],"around":[57],"promoters":[58],"underwent":[59],"dramatic":[60],"reestablishment,":[61],"which":[62,105],"consistent":[64],"cycle.":[68],"Dynamics":[69],"of":[70,110,131,139],"position":[72],"were":[76,96],"delayed":[77],"compared":[78],"to":[79],"fertilized":[80],"embryos.":[81],"Subsequently,":[82],"aberrant":[87],"expression":[89],"levels":[90],"inner":[92],"mass":[94],"(ICM)":[95],"positively":[97],"correlated":[98],"promoter":[100,140],"NDRs":[101],"donor":[103,114,132],"cells,":[104],"indicated":[106],"memory":[109,138],"occupancy":[112],"was":[116,134],"a":[117],"potential":[118],"barrier":[119],"SCNT-mediated":[121],"reprogramming.":[122],"further":[124],"confirmed":[125],"histone":[128],"acetylation":[129],"level":[130],"associated":[135],"NDRs.":[141],"Our":[142],"study":[143],"provides":[144],"insight":[145],"reconfiguration":[148],"preimplantation":[151]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2022-06-25T00:00:00"}