{"id":"https://openalex.org/W4283371034","doi":"https://doi.org/10.3390/life12070942","title":"Decellularized Wharton Jelly Implants Do Not Trigger Collagen and Cartilaginous Tissue Production in Tracheal Injury in Rabbits","display_name":"Decellularized Wharton Jelly Implants Do Not Trigger Collagen and Cartilaginous Tissue Production in Tracheal Injury in Rabbits","publication_year":2022,"publication_date":"2022-06-23","ids":{"openalex":"https://openalex.org/W4283371034","doi":"https://doi.org/10.3390/life12070942","pmid":"https://pubmed.ncbi.nlm.nih.gov/35888031","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9316797"},"language":"en","primary_location":{"id":"doi:10.3390/life12070942","doi":"https://doi.org/10.3390/life12070942","is_oa":true,"landing_page_url":"https://doi.org/10.3390/life12070942","pdf_url":"https://www.mdpi.com/2075-1729/12/7/942/pdf?version=1655973102","source":{"id":"https://openalex.org/S4210200765","display_name":"Life","issn_l":"2075-1729","issn":["2075-1729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2075-1729/12/7/942/pdf?version=1655973102","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052256178","display_name":"K\u00e1tia Martins Foltz","orcid":"https://orcid.org/0000-0003-2854-5603","observed_orcids":["https://orcid.org/0000-0003-2854-5603"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Katia Martins Foltz","raw_affiliation_strings":["Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-2854-5603","affiliations":[{"raw_affiliation_string":"Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021127599","display_name":"Aloysio Enck Neto","orcid":"https://orcid.org/0000-0003-0458-5707","observed_orcids":["https://orcid.org/0000-0003-0458-5707"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Aloysio Enck Neto","raw_affiliation_strings":["Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-0458-5707","affiliations":[{"raw_affiliation_string":"Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102720527","display_name":"J\u00falio C\u00e9sar Francisco","orcid":"https://orcid.org/0000-0003-1970-6399","observed_orcids":["https://orcid.org/0000-0003-1970-6399"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"J\u00falio C\u00e9sar Francisco","raw_affiliation_strings":["Experimental Laboratory of Institute of Biological and Health Sciences, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-1970-6399","affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Institute of Biological and Health Sciences, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052104978","display_name":"Rossana Baggio Simeoni","orcid":"https://orcid.org/0000-0002-9976-5809","observed_orcids":["https://orcid.org/0000-0002-9976-5809"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rossana Baggio Simeoni","raw_affiliation_strings":["Experimental Laboratory of Institute of Biological and Health Sciences, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Institute of Biological and Health Sciences, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046970114","display_name":"Anna Flavia Ribeiro dos Santos Miggiolaro","orcid":"https://orcid.org/0000-0002-8497-400X","observed_orcids":["https://orcid.org/0000-0002-8497-400X"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Anna Fl\u00e1via Ribeiro dos Santos Miggiolaro","raw_affiliation_strings":["Experimental Laboratory of Institute of Biological and Health Sciences, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Laboratory of Institute of Biological and Health Sciences, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025288180","display_name":"Thatyanne Gradowski Farias da Costa do Nascimento","orcid":"https://orcid.org/0000-0002-4387-5857","observed_orcids":["https://orcid.org/0000-0002-4387-5857"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Thatyanne Gradowski do Nascimento","raw_affiliation_strings":["Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-4387-5857","affiliations":[{"raw_affiliation_string":"Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039361062","display_name":"Bassam Felipe Mogharbel","orcid":"https://orcid.org/0000-0002-1338-0693","observed_orcids":["https://orcid.org/0000-0002-1338-0693"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bassam Felipe Mogharbel","raw_affiliation_strings":["Advanced Therapy and Cellular Biotechnology in Regenerative Medicine Research Group, Pel\u00e9 Pequeno Pr\u00edncipe Research Institute & Pequeno Pr\u00edncipe Faculties (FPP), Curitiba 80250-060, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-1338-0693","affiliations":[{"raw_affiliation_string":"Advanced Therapy and Cellular Biotechnology in Regenerative Medicine Research Group, Pel\u00e9 Pequeno Pr\u00edncipe Research Institute & Pequeno Pr\u00edncipe Faculties (FPP), Curitiba 80250-060, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032649134","display_name":"Katherine Athayde Teixeira de Carvalho","orcid":"https://orcid.org/0000-0003-4860-2855","observed_orcids":["https://orcid.org/0000-0003-4860-2855"]},"institutions":[{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Katherine Athayde Teixeira de Carvalho","raw_affiliation_strings":["Advanced Therapy and Cellular Biotechnology in Regenerative Medicine Research Group, Pel\u00e9 Pequeno Pr\u00edncipe Research Institute & Pequeno Pr\u00edncipe Faculties (FPP), Curitiba 80250-060, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-4860-2855","affiliations":[{"raw_affiliation_string":"Advanced Therapy and Cellular Biotechnology in Regenerative Medicine Research Group, Pel\u00e9 Pequeno Pr\u00edncipe Research Institute & Pequeno Pr\u00edncipe Faculties (FPP), Curitiba 80250-060, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083729143","display_name":"Jos\u00e9 Rocha Faria\u2010Neto","orcid":"https://orcid.org/0000-0002-1397-0634","observed_orcids":["https://orcid.org/0000-0002-1397-0634"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Rocha Faria-Neto","raw_affiliation_strings":["Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-1397-0634","affiliations":[{"raw_affiliation_string":"Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084312073","display_name":"L\u00facia de Noronha","orcid":"https://orcid.org/0000-0003-0310-7164","observed_orcids":["https://orcid.org/0000-0003-0310-7164"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"L\u00facia de Noronha","raw_affiliation_strings":["Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","Laboratory of Experimental Pathology, Graduate Program of Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-0310-7164","affiliations":[{"raw_affiliation_string":"Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]},{"raw_affiliation_string":"Laboratory of Experimental Pathology, Graduate Program of Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000794330","display_name":"Luiz C\u00e9sar Guarita-Souza","orcid":"https://orcid.org/0000-0003-2781-9705","observed_orcids":["https://orcid.org/0000-0003-2781-9705","https://orcid.org/0000-0002-6910-9077"]},"institutions":[{"id":"https://openalex.org/I176838256","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1","ror":"https://ror.org/02x1vjk79","country_code":"BR","type":"education","lineage":["https://openalex.org/I176838256"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luiz C\u00e9sar Guarita-Souza","raw_affiliation_strings":["Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-2781-9705","affiliations":[{"raw_affiliation_string":"Graduate Program in Health Sciences, School of Medicine, Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 (PUCPR), Curitiba 80215-901, Paran\u00e1, Brazil","institution_ids":["https://openalex.org/I176838256"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052256178"],"corresponding_institution_ids":["https://openalex.org/I176838256"],"apc_list":{"value":1800,"currency":"CHF","value_usd":1885},"apc_paid":{"value":1800,"currency":"CHF","value_usd":1885},"fwci":1.8953,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.84652005,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"12","issue":"7","first_page":"942","last_page":"942"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11260","display_name":"Tracheal and airway disorders","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tracheal-injury","display_name":"tracheal injury","score":0.9629999995231628},{"id":"https://openalex.org/keywords/tracheal-defects","display_name":"tracheal defects","score":0.7549999952316284},{"id":"https://openalex.org/keywords/tissue-regeneration","display_name":"tissue regeneration","score":0.6259999871253967},{"id":"https://openalex.org/keywords/biomaterial-scaffolds","display_name":"biomaterial scaffolds","score":0.7620000243186951},{"id":"https://openalex.org/keywords/type-i-collagen","display_name":"type I collagen","score":0.6420000195503235},{"id":"https://openalex.org/keywords/type-iii-collagen","display_name":"type III collagen","score":0.9990000128746033},{"id":"https://openalex.org/keywords/aggrecan","display_name":"aggrecan","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cartilage","display_name":"cartilage","score":0.6110000014305115},{"id":"https://openalex.org/keywords/tracheal-stenosis","display_name":"tracheal stenosis","score":0.5699999928474426},{"id":"https://openalex.org/keywords/rabbit-model","display_name":"rabbit model","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.9434117674827576},{"id":"https://openalex.org/C2778414984","wikidata":"https://www.wikidata.org/wiki/Q865663","display_name":"Biomaterial","level":2,"score":0.590045154094696},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.5880163311958313},{"id":"https://openalex.org/C197534660","wikidata":"https://www.wikidata.org/wiki/Q21121862","display_name":"Aggrecan","level":5,"score":0.49522319436073303},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.4888996183872223},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4594382643699646},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.42591673135757446},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.4252042770385742},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.4238273501396179},{"id":"https://openalex.org/C2781411149","wikidata":"https://www.wikidata.org/wiki/Q486975","display_name":"Implant","level":2,"score":0.41141289472579956},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3576260209083557},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.34775015711784363},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32958725094795227},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2640722990036011},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.223075270652771},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2149994969367981},{"id":"https://openalex.org/C3020332539","wikidata":"https://www.wikidata.org/wiki/Q2014564","display_name":"Articular cartilage","level":4,"score":0.08900624513626099},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.08900204300880432},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/life12070942","doi":"https://doi.org/10.3390/life12070942","is_oa":true,"landing_page_url":"https://doi.org/10.3390/life12070942","pdf_url":"https://www.mdpi.com/2075-1729/12/7/942/pdf?version=1655973102","source":{"id":"https://openalex.org/S4210200765","display_name":"Life","issn_l":"2075-1729","issn":["2075-1729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life","raw_type":"journal-article"},{"id":"pmid:35888031","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35888031","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9316797","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9316797/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:69ab9e60aa7d489ca775dcf0d85adbb1","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/69ab9e60aa7d489ca775dcf0d85adbb1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Life, Vol 12, Iss 7, p 942 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/life12070942","doi":"https://doi.org/10.3390/life12070942","is_oa":true,"landing_page_url":"https://doi.org/10.3390/life12070942","pdf_url":"https://www.mdpi.com/2075-1729/12/7/942/pdf?version=1655973102","source":{"id":"https://openalex.org/S4210200765","display_name":"Life","issn_l":"2075-1729","issn":["2075-1729"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Life","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4283371034.pdf","grobid_xml":"https://content.openalex.org/works/W4283371034.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1990088683","https://openalex.org/W2111451273","https://openalex.org/W2140496034","https://openalex.org/W2166189112","https://openalex.org/W2171785627","https://openalex.org/W2340065219","https://openalex.org/W2469952414","https://openalex.org/W2544572673","https://openalex.org/W2562257527","https://openalex.org/W2591002979","https://openalex.org/W2756746063","https://openalex.org/W2767916391","https://openalex.org/W2769292498","https://openalex.org/W2778631507","https://openalex.org/W2786647296","https://openalex.org/W2791840887","https://openalex.org/W2891479251","https://openalex.org/W2939654433","https://openalex.org/W2941661312","https://openalex.org/W2964708992","https://openalex.org/W2990978095","https://openalex.org/W3007479821","https://openalex.org/W3007928490","https://openalex.org/W3014452827","https://openalex.org/W3034195806","https://openalex.org/W3036594169","https://openalex.org/W3194241407","https://openalex.org/W3195027392","https://openalex.org/W3210687018","https://openalex.org/W4213452490"],"related_works":["https://openalex.org/W4399892503","https://openalex.org/W3007479821","https://openalex.org/W2288817082","https://openalex.org/W4379598906","https://openalex.org/W1989084980","https://openalex.org/W2748742702","https://openalex.org/W2491235868","https://openalex.org/W2464497687","https://openalex.org/W2601393827","https://openalex.org/W2510668192"],"abstract_inverted_index":{"Background:":[0],"Tracheal":[1],"lesions":[2],"are":[3],"pathologies":[4],"derived":[5],"from":[6],"the":[7,19,25,31,34,45,61,68,146,155,181,184,192],"most":[8],"diverse":[9],"insults":[10],"that":[11,190],"can":[12,40],"result":[13],"in":[14,73,82,210],"a":[15,27,54,77,102,167,199],"fatal":[16],"outcome.":[17],"Despite":[18],"number":[20],"of":[21,33,63,70,111,180],"techniques":[22],"designed":[23],"for":[24,201],"treatment,":[26],"limiting":[28],"factor":[29],"is":[30,58],"extent":[32],"extraction.":[35],"Therefore,":[36],"strategies":[37],"with":[38,150],"biomaterials":[39],"restructure":[41],"tissues":[42],"and":[43,109,139,154,170],"maintain":[44],"organ\u2019s":[46],"functionality,":[47],"like":[48],"decellularized":[49,71,112],"Wharton\u2019s":[50],"jelly":[51],"(WJ)":[52],"as":[53,166,176,198],"scaffold.":[55],"The":[56,114,161],"aim":[57],"to":[59,76,101,164],"analyze":[60],"capacity":[62],"tracheal":[64,78,103,107,126],"tissue":[65,202,212],"regeneration":[66],"after":[67,120],"implantation":[69,110],"WJ":[72,193],"rabbits":[74,90],"submitted":[75,100],"defect.":[79],"Methods:":[80],"An":[81],"vivo":[83],"experimental":[84],"study":[85],"was":[86],"undertaken":[87],"using":[88],"twenty":[89],"separated":[91],"into":[92,183],"two":[93],"groups":[94,147],"(n":[95],"=":[96,130,152,158],"10).":[97],"Group":[98],"1":[99],"defect,":[104,108],"group":[105],"2":[106],"WJ.":[113],"analyses":[115],"were":[116],"performed":[117],"30":[118],"days":[119],"surgery":[121],"through":[122],"immunohistochemistry.":[123],"Results:":[124],"Inner":[125],"area":[127],"diameter":[128],"(p":[129],"0.643)":[131],"didn\u2019t":[132],"show":[133],"significance.":[134],"Collagen":[135],"type":[136],"I,":[137],"III,":[138],"Aggrecan":[140,156],"highlighted":[141],"no":[142],"significant":[143],"difference":[144],"between":[145],"(both":[148],"collagens":[149],"p":[151,157],"0.445":[153],"0.4).":[159],"Conclusion:":[160],"scaffold":[162],"appears":[163],"fit":[165],"heterologous":[168],"implant":[169],"did":[171,205],"not":[172,206],"trigger":[173],"reactions":[174],"such":[175],"rejection":[177],"or":[178],"extrusion":[179],"material":[182],"recipient.":[185],"However,":[186],"these":[187],"results":[188],"suggested":[189],"although":[191],"matrix":[194],"presents":[195],"several":[196],"characteristics":[197],"biomaterial":[200],"regeneration,":[203],"it":[204],"display":[207],"histopathological":[208],"benefits":[209],"trachea":[211],"regeneration.":[213]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-06-25T00:00:00"}