{"id":"https://openalex.org/W4283323866","doi":"https://doi.org/10.1155/2022/3399311","title":"Identification of ABCA5 among ATP-Binding Cassette Transporter Family as a New Biomarker for Colorectal Cancer","display_name":"Identification of ABCA5 among ATP-Binding Cassette Transporter Family as a New Biomarker for Colorectal Cancer","publication_year":2022,"publication_date":"2022-06-22","ids":{"openalex":"https://openalex.org/W4283323866","doi":"https://doi.org/10.1155/2022/3399311","pmid":"https://pubmed.ncbi.nlm.nih.gov/35783152","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9242773"},"language":"en","primary_location":{"id":"doi:10.1155/2022/3399311","doi":"https://doi.org/10.1155/2022/3399311","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2022/3399311","pdf_url":"https://downloads.hindawi.com/journals/jo/2022/3399311.pdf","source":{"id":"https://openalex.org/S207014961","display_name":"Journal of Oncology","issn_l":"1687-8450","issn":["1687-8450","1687-8469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/jo/2022/3399311.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071839233","display_name":"Pei-Long Bu","orcid":"https://orcid.org/0000-0001-8971-0225","observed_orcids":["https://orcid.org/0000-0001-8971-0225"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]},{"id":"https://openalex.org/I4210087761","display_name":"Henan University Huaihe Hospital and Huaihe Clinical Institute","ror":"https://ror.org/002mm7c07","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peilong Bu","raw_affiliation_strings":["Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China"],"raw_orcid":"https://orcid.org/0000-0001-8971-0225","affiliations":[{"raw_affiliation_string":"Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China","institution_ids":["https://openalex.org/I173899330","https://openalex.org/I4210087761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047336507","display_name":"Yafei Xiao","orcid":"https://orcid.org/0000-0002-7704-8622","observed_orcids":["https://orcid.org/0000-0002-7704-8622"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]},{"id":"https://openalex.org/I4210087761","display_name":"Henan University Huaihe Hospital and Huaihe Clinical Institute","ror":"https://ror.org/002mm7c07","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yafei Xiao","raw_affiliation_strings":["Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China"],"raw_orcid":"https://orcid.org/0000-0002-7704-8622","affiliations":[{"raw_affiliation_string":"Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China","institution_ids":["https://openalex.org/I173899330","https://openalex.org/I4210087761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069213277","display_name":"Shaowen Hu","orcid":"https://orcid.org/0000-0003-2421-9501","observed_orcids":["https://orcid.org/0000-0003-2421-9501"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]},{"id":"https://openalex.org/I4210087761","display_name":"Henan University Huaihe Hospital and Huaihe Clinical Institute","ror":"https://ror.org/002mm7c07","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaowen Hu","raw_affiliation_strings":["Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China"],"raw_orcid":"https://orcid.org/0000-0003-2421-9501","affiliations":[{"raw_affiliation_string":"Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China","institution_ids":["https://openalex.org/I173899330","https://openalex.org/I4210087761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027088593","display_name":"Xiaowei Jiang","orcid":"https://orcid.org/0000-0002-9622-4409","observed_orcids":["https://orcid.org/0000-0002-9622-4409"]},"institutions":[{"id":"https://openalex.org/I4210144384","display_name":"Third Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/039nw9e11","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144384"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaowei Jiang","raw_affiliation_strings":["Department of Pediatric Orthopedics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China"],"raw_orcid":"https://orcid.org/0000-0002-9622-4409","affiliations":[{"raw_affiliation_string":"Department of Pediatric Orthopedics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China","institution_ids":["https://openalex.org/I4210144384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103208533","display_name":"Cong Tan","orcid":"https://orcid.org/0000-0001-6912-4579","observed_orcids":["https://orcid.org/0000-0001-6912-4579","https://orcid.org/0000-0002-7985-6682"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cong Tan","raw_affiliation_strings":["Institute of Biomedical Informatics, Cell Signal Transduction Laboratory, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China"],"raw_orcid":"https://orcid.org/0000-0002-7985-6682","affiliations":[{"raw_affiliation_string":"Institute of Biomedical Informatics, Cell Signal Transduction Laboratory, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China","institution_ids":["https://openalex.org/I173899330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039518019","display_name":"Mengyuan Qiu","orcid":"https://orcid.org/0000-0003-3730-4457","observed_orcids":["https://orcid.org/0000-0003-3730-4457"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengyuan Qiu","raw_affiliation_strings":["Institute of Biomedical Informatics, Cell Signal Transduction Laboratory, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China"],"raw_orcid":"https://orcid.org/0000-0003-3730-4457","affiliations":[{"raw_affiliation_string":"Institute of Biomedical Informatics, Cell Signal Transduction Laboratory, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China","institution_ids":["https://openalex.org/I173899330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103247885","display_name":"Wanting Huang","orcid":"https://orcid.org/0000-0002-2283-4351","observed_orcids":["https://orcid.org/0000-0002-2283-4351"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanting Huang","raw_affiliation_strings":["Institute of Biomedical Informatics, Cell Signal Transduction Laboratory, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China"],"raw_orcid":"https://orcid.org/0000-0002-2283-4351","affiliations":[{"raw_affiliation_string":"Institute of Biomedical Informatics, Cell Signal Transduction Laboratory, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China","institution_ids":["https://openalex.org/I173899330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100348209","display_name":"Mengmeng Li","orcid":"https://orcid.org/0000-0002-8623-331X","observed_orcids":["https://orcid.org/0000-0002-8623-331X"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]},{"id":"https://openalex.org/I4210087761","display_name":"Henan University Huaihe Hospital and Huaihe Clinical Institute","ror":"https://ror.org/002mm7c07","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengmeng Li","raw_affiliation_strings":["Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China"],"raw_orcid":"https://orcid.org/0000-0002-8623-331X","affiliations":[{"raw_affiliation_string":"Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China","institution_ids":["https://openalex.org/I173899330","https://openalex.org/I4210087761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055616796","display_name":"Quanying Li","orcid":"https://orcid.org/0000-0001-6447-4289","observed_orcids":["https://orcid.org/0000-0001-6447-4289"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]},{"id":"https://openalex.org/I4210087761","display_name":"Henan University Huaihe Hospital and Huaihe Clinical Institute","ror":"https://ror.org/002mm7c07","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Quanying Li","raw_affiliation_strings":["Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China"],"raw_orcid":"https://orcid.org/0000-0001-6447-4289","affiliations":[{"raw_affiliation_string":"Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China","institution_ids":["https://openalex.org/I173899330","https://openalex.org/I4210087761"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101696030","display_name":"Changjiang Qin","orcid":"https://orcid.org/0000-0003-4295-4964","observed_orcids":["https://orcid.org/0000-0003-4295-4964"]},"institutions":[{"id":"https://openalex.org/I173899330","display_name":"Henan University","ror":"https://ror.org/003xyzq10","country_code":"CN","type":"education","lineage":["https://openalex.org/I173899330"]},{"id":"https://openalex.org/I4210087761","display_name":"Henan University Huaihe Hospital and Huaihe Clinical Institute","ror":"https://ror.org/002mm7c07","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Changjiang Qin","raw_affiliation_strings":["Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China"],"raw_orcid":"https://orcid.org/0000-0003-4295-4964","affiliations":[{"raw_affiliation_string":"Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, China","institution_ids":["https://openalex.org/I173899330","https://openalex.org/I4210087761"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101696030"],"corresponding_institution_ids":["https://openalex.org/I173899330","https://openalex.org/I4210087761"],"apc_list":{"value":2550,"currency":"USD","value_usd":2550},"apc_paid":{"value":2550,"currency":"USD","value_usd":2550},"fwci":0.4512,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.5922045,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2022","issue":null,"first_page":"1","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.011500000022351742,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abca5","display_name":"ABCA5","score":0.9980000257492065},{"id":"https://openalex.org/keywords/abc-transporters","display_name":"ABC transporters","score":0.7710000276565552},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9779999852180481},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.7400000095367432},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8809999823570251},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.7379999756813049},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.7319999933242798},{"id":"https://openalex.org/keywords/protein-protein-interaction-network","display_name":"protein-protein interaction network","score":0.9570000171661377},{"id":"https://openalex.org/keywords/gene-co-expression-network","display_name":"gene co-expression network","score":0.7289999723434448},{"id":"https://openalex.org/keywords/the-cancer-genome-atlas","display_name":"TCGA","score":0.6299999952316284},{"id":"https://openalex.org/keywords/geo-datasets","display_name":"GEO datasets","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8684917688369751},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.7467744946479797},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6816313862800598},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6814241409301758},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.6050235033035278},{"id":"https://openalex.org/C44312359","wikidata":"https://www.wikidata.org/wiki/Q286958","display_name":"ATP-binding cassette transporter","level":4,"score":0.41685715317726135},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.40907832980155945},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.38776302337646484},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3561273217201233},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16587397456169128},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1485767364501953},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.05963855981826782},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1155/2022/3399311","doi":"https://doi.org/10.1155/2022/3399311","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2022/3399311","pdf_url":"https://downloads.hindawi.com/journals/jo/2022/3399311.pdf","source":{"id":"https://openalex.org/S207014961","display_name":"Journal of Oncology","issn_l":"1687-8450","issn":["1687-8450","1687-8469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Oncology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9242773","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9242773","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Oncol","raw_type":"Text"},{"id":"pmid:35783152","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35783152","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of oncology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:84e59e8328304645a6e0fc8d969f08cc","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/84e59e8328304645a6e0fc8d969f08cc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Oncology, Vol 2022 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/2022/3399311","doi":"https://doi.org/10.1155/2022/3399311","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2022/3399311","pdf_url":"https://downloads.hindawi.com/journals/jo/2022/3399311.pdf","source":{"id":"https://openalex.org/S207014961","display_name":"Journal of Oncology","issn_l":"1687-8450","issn":["1687-8450","1687-8469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1812906909","display_name":null,"funder_award_id":"SYL20060192","funder_id":"https://openalex.org/F4320323845","funder_display_name":"Natural Science Foundation of Henan Province"},{"id":"https://openalex.org/G2148192236","display_name":null,"funder_award_id":"19A320020","funder_id":"https://openalex.org/F4320323845","funder_display_name":"Natural Science Foundation of Henan Province"},{"id":"https://openalex.org/G2157138472","display_name":null,"funder_award_id":"192102310099","funder_id":"https://openalex.org/F4320322878","funder_display_name":"Henan University"},{"id":"https://openalex.org/G2468504537","display_name":null,"funder_award_id":"SBGJ202002097","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G346653733","display_name":null,"funder_award_id":"NSFC-U1504818","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3569533801","display_name":null,"funder_award_id":"SBGJ202002097","funder_id":"https://openalex.org/F4320323845","funder_display_name":"Natural Science Foundation of Henan Province"},{"id":"https://openalex.org/G3723774587","display_name":null,"funder_award_id":"172102310152","funder_id":"https://openalex.org/F4320323845","funder_display_name":"Natural Science Foundation of Henan Province"},{"id":"https://openalex.org/G4171685170","display_name":null,"funder_award_id":"SBGJ202002097","funder_id":"https://openalex.org/F4320322878","funder_display_name":"Henan University"},{"id":"https://openalex.org/G4324043103","display_name":null,"funder_award_id":"NSFC\u2013U1504818","funder_id":"https://openalex.org/F4320322878","funder_display_name":"Henan University"},{"id":"https://openalex.org/G4491320775","display_name":null,"funder_award_id":"172102310152","funder_id":"https://openalex.org/F4320322878","funder_display_name":"Henan University"},{"id":"https://openalex.org/G509753847","display_name":null,"funder_award_id":"NSFC\u2013U1504818","funder_id":"https://openalex.org/F4320323845","funder_display_name":"Natural Science Foundation of Henan Province"},{"id":"https://openalex.org/G511100554","display_name":null,"funder_award_id":"19A320020","funder_id":"https://openalex.org/F4320322878","funder_display_name":"Henan University"},{"id":"https://openalex.org/G5216311028","display_name":null,"funder_award_id":"SYL20060192","funder_id":"https://openalex.org/F4320322878","funder_display_name":"Henan University"},{"id":"https://openalex.org/G5292294859","display_name":null,"funder_award_id":"172102310152","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5771134821","display_name":null,"funder_award_id":"192102310099","funder_id":"https://openalex.org/F4320323845","funder_display_name":"Natural Science Foundation of Henan Province"},{"id":"https://openalex.org/G5814648590","display_name":null,"funder_award_id":"182300410359","funder_id":"https://openalex.org/F4320323845","funder_display_name":"Natural Science Foundation of Henan Province"},{"id":"https://openalex.org/G6889274167","display_name":null,"funder_award_id":"182300410359","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6900777447","display_name":null,"funder_award_id":"SYL20060192","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6929655298","display_name":null,"funder_award_id":"182300410359","funder_id":"https://openalex.org/F4320322878","funder_display_name":"Henan University"},{"id":"https://openalex.org/G7654665615","display_name":null,"funder_award_id":"19A320020","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8440032159","display_name":null,"funder_award_id":"192102310099","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322878","display_name":"Henan University","ror":"https://ror.org/003xyzq10"},{"id":"https://openalex.org/F4320323845","display_name":"Natural Science Foundation of Henan Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4283323866.pdf","grobid_xml":"https://content.openalex.org/works/W4283323866.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W788737191","https://openalex.org/W968579337","https://openalex.org/W1480357432","https://openalex.org/W1481943068","https://openalex.org/W1557844382","https://openalex.org/W1976879156","https://openalex.org/W1979552352","https://openalex.org/W1981045629","https://openalex.org/W1981304865","https://openalex.org/W1981751729","https://openalex.org/W1984803858","https://openalex.org/W2014504966","https://openalex.org/W2041158331","https://openalex.org/W2041600084","https://openalex.org/W2046359558","https://openalex.org/W2047550476","https://openalex.org/W2050767064","https://openalex.org/W2054438658","https://openalex.org/W2054750511","https://openalex.org/W2056772956","https://openalex.org/W2064613880","https://openalex.org/W2064645605","https://openalex.org/W2082875692","https://openalex.org/W2082975783","https://openalex.org/W2085129499","https://openalex.org/W2089050591","https://openalex.org/W2098885754","https://openalex.org/W2104104624","https://openalex.org/W2107919309","https://openalex.org/W2120661430","https://openalex.org/W2131186576","https://openalex.org/W2131464730","https://openalex.org/W2133210805","https://openalex.org/W2136166312","https://openalex.org/W2154843786","https://openalex.org/W2159803625","https://openalex.org/W2161926177","https://openalex.org/W2162097287","https://openalex.org/W2168070336","https://openalex.org/W2198944118","https://openalex.org/W2239425212","https://openalex.org/W2402009271","https://openalex.org/W2540066416","https://openalex.org/W2571675127","https://openalex.org/W2581492008","https://openalex.org/W2605774152","https://openalex.org/W2615682460","https://openalex.org/W2751118264","https://openalex.org/W2792536676","https://openalex.org/W2884502104","https://openalex.org/W2889646458","https://openalex.org/W2900448860","https://openalex.org/W2901777587","https://openalex.org/W2927489979","https://openalex.org/W2931968869","https://openalex.org/W2947358336","https://openalex.org/W2951933258","https://openalex.org/W3019435489","https://openalex.org/W3022308777","https://openalex.org/W3037339101","https://openalex.org/W3039424685","https://openalex.org/W3042960411","https://openalex.org/W3093539631","https://openalex.org/W3103972666","https://openalex.org/W3119005666","https://openalex.org/W3132740442","https://openalex.org/W3148172149","https://openalex.org/W3165690650","https://openalex.org/W4205134630","https://openalex.org/W4235607015"],"related_works":["https://openalex.org/W3049129026","https://openalex.org/W4315497990","https://openalex.org/W2910899598","https://openalex.org/W4362592581","https://openalex.org/W3209090874","https://openalex.org/W2965990268","https://openalex.org/W7117890421","https://openalex.org/W3119011002","https://openalex.org/W4407087321","https://openalex.org/W4319986284"],"abstract_inverted_index":{"Background:":[0],"The":[1,14,90,122],"increasing":[2],"incidence":[3],"and":[4,40,43,46,51,83,95,111,130,138,144,155,188],"mortality":[5],"of":[6,22,29,61,89,104,124,190],"colorectal":[7],"cancer":[8],"(CRC)":[9],"urgently":[10],"requires":[11],"updated":[12],"biomarkers.":[13],"ABC":[15,77],"transporter":[16,78],"family":[17,21,80],"is":[18],"a":[19],"widespread":[20],"membrane-bound":[23],"proteins":[24],"involved":[25],"in":[26,58,63,75,135,192],"the":[27,59,64,76,125,173,193],"transportation":[28],"substrates":[30],"associated":[31],"with":[32],"ATP":[33],"hydrolysis,":[34],"including":[35,107],"metabolites,":[36],"amino":[37],"acids,":[38],"peptides":[39],"proteins,":[41],"sterols":[42],"lipids,":[44],"organic":[45],"inorganic":[47],"ions,":[48],"sugars,":[49],"metals,":[50],"drugs.":[52],"They":[53],"play":[54],"an":[55],"important":[56],"role":[57],"maintenance":[60],"homeostasis":[62],"body.":[65],"Purpose:":[66],"This":[67],"study":[68],"aims":[69],"to":[70],"search":[71],"for":[72,81,120,141,165,185],"new":[73],"markers":[74],"gene":[79,158,169],"diagnostic":[82],"prognostic":[84],"purposes":[85],"through":[86],"data":[87],"mining":[88],"Cancer":[91],"Genome":[92],"Atlas":[93],"(TCGA)":[94],"GEO":[96],"(Gene":[97],"Expression":[98],"Omnibus)":[99],"datasets.":[100],"Methods:":[101],"A":[102],"total":[103],"980":[105],"samples,":[106],"684":[108],"CRC":[109,191],"patients":[110],"296":[112],"controls":[113],"from":[114],"five":[115],"different":[116],"datasets,":[117],"were":[118,133,162],"included":[119],"analysis.":[121,167],"construction":[123],"PPI":[126],"(protein-protein":[127],"interaction)":[128],"network":[129,160],"pathway":[131],"analysis":[132],"performed":[134],"STRING":[136],"database":[137],"DAVID":[139],"(database":[140],"annotation,":[142],"visualization,":[143],"integrated":[145],"discovery),":[146],"respectively.":[147],"In":[148],"addition,":[149],"GSEA":[150],"(gene":[151],"set":[152],"enrichment":[153],"analysis)":[154,161],"WGCNA":[156],"(weighted":[157],"co-expression":[159],"also":[163],"used":[164],"functional":[166],"Results:":[168],"was":[170],"retained":[171],"among":[172],"49":[174],"genes.":[175],"Conclusions:":[176],"expression":[177],"have":[178],"better":[179,186],"OS,":[180],"which":[181],"can":[182],"provide":[183],"guidance":[184],"management":[187],"treatment":[189],"future.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2022-06-24T00:00:00"}