{"id":"https://openalex.org/W4283220710","doi":"https://doi.org/10.1007/s10753-022-01643-y","title":"Aerobic Exercise Attenuates Kidney Injury, Improves Physical Performance, and Increases Antioxidant Defenses in Lungs of Adenine-Induced Chronic Kidney Disease Mice","display_name":"Aerobic Exercise Attenuates Kidney Injury, Improves Physical Performance, and Increases Antioxidant Defenses in Lungs of Adenine-Induced Chronic Kidney Disease Mice","publication_year":2022,"publication_date":"2022-06-21","ids":{"openalex":"https://openalex.org/W4283220710","doi":"https://doi.org/10.1007/s10753-022-01643-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/35727396"},"language":"en","primary_location":{"id":"doi:10.1007/s10753-022-01643-y","doi":"https://doi.org/10.1007/s10753-022-01643-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10753-022-01643-y","pdf_url":null,"source":{"id":"https://openalex.org/S127393932","display_name":"Inflammation","issn_l":"0360-3997","issn":["0360-3997","1573-2576"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://repositorio.udesc.br/handle/UDESC/2883","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050899782","display_name":"D\u00e9bora Petry Moecke","orcid":"https://orcid.org/0000-0003-0905-9722","observed_orcids":["https://orcid.org/0000-0003-0905-9722"]},"institutions":[{"id":"https://openalex.org/I164790352","display_name":"Universidade do Estado de Santa Catarina","ror":"https://ror.org/03ztsbk67","country_code":"BR","type":"education","lineage":["https://openalex.org/I164790352"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"D\u00e9bora Melissa Petry Moecke","raw_affiliation_strings":["Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I164790352"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028461831","display_name":"Gisele Henrique Cardoso Martins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gisele Henrique Cardoso Martins","raw_affiliation_strings":["Laboratory of Cellular Defense (LABDEF), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Cellular Defense (LABDEF), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019550177","display_name":"Thaine Cristina Garlet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I164790352","display_name":"Universidade do Estado de Santa Catarina","ror":"https://ror.org/03ztsbk67","country_code":"BR","type":"education","lineage":["https://openalex.org/I164790352"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Thaine Cristina Garlet","raw_affiliation_strings":["Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I164790352"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063440141","display_name":"Kelly Cattelan Bonorino","orcid":"https://orcid.org/0000-0003-0797-5778","observed_orcids":["https://orcid.org/0000-0003-0797-5778"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Kelly Cattelan Bonorino","raw_affiliation_strings":["Laboratory of Neurobiology of Pain and Inflammation (LANDI), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurobiology of Pain and Inflammation (LANDI), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027873564","display_name":"Marilia Gabriela Luciani","orcid":"https://orcid.org/0000-0003-2567-4573","observed_orcids":["https://orcid.org/0000-0003-2567-4573"]},"institutions":[{"id":"https://openalex.org/I164790352","display_name":"Universidade do Estado de Santa Catarina","ror":"https://ror.org/03ztsbk67","country_code":"BR","type":"education","lineage":["https://openalex.org/I164790352"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marilia Gabriela Luciani","raw_affiliation_strings":["Center for Agricultural Sciences (CAV), Universidade Estadual de Santa Catarina (UDESC), Lages, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Agricultural Sciences (CAV), Universidade Estadual de Santa Catarina (UDESC), Lages, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I164790352"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032383137","display_name":"Monique Coelho Bion","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Monique Bion","raw_affiliation_strings":["Laboratory of Cellular Defense (LABDEF), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Cellular Defense (LABDEF), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030067882","display_name":"B\u00e1rbara dos Santos","orcid":"https://orcid.org/0000-0001-7496-410X","observed_orcids":["https://orcid.org/0000-0001-7496-410X"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Barbara dos Santos","raw_affiliation_strings":["Laboratory of Cellular Defense (LABDEF), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Cellular Defense (LABDEF), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071787473","display_name":"Monique da Silva Gevaerd","orcid":"https://orcid.org/0000-0002-1405-3969","observed_orcids":["https://orcid.org/0000-0002-1405-3969"]},"institutions":[{"id":"https://openalex.org/I164790352","display_name":"Universidade do Estado de Santa Catarina","ror":"https://ror.org/03ztsbk67","country_code":"BR","type":"education","lineage":["https://openalex.org/I164790352"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Monique da Silva Gevaerd","raw_affiliation_strings":["Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I164790352"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008703563","display_name":"Jamil Assreuy Filho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jamil Assreuy Filho","raw_affiliation_strings":["Nitric Oxide Pharmacology Laboratory, Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nitric Oxide Pharmacology Laboratory, Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009990459","display_name":"Adair R.S. Santos","orcid":"https://orcid.org/0000-0002-6435-4698","observed_orcids":["https://orcid.org/0000-0002-6435-4698"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Adair Roberto Soares dos Santos","raw_affiliation_strings":["Laboratory of Neurobiology of Pain and Inflammation (LANDI), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurobiology of Pain and Inflammation (LANDI), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019207723","display_name":"Daniella Serafin Couto Vieira","orcid":"https://orcid.org/0000-0003-0188-6010","observed_orcids":["https://orcid.org/0000-0003-0188-6010"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]},{"id":"https://openalex.org/I4210126369","display_name":"Polydoro Ernani de S\u00e3o Thiago University Hospital","ror":"https://ror.org/0303d1x26","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210126369"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daniella Serafin Couto Vieira","raw_affiliation_strings":["Polydoro Ernani de S\u00e3o Thiago University Hospital, Universidade Federal de Santa Catarina (HU/UFSC), Pathological Anatomy Service, Florian\u00f3polis, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Polydoro Ernani de S\u00e3o Thiago University Hospital, Universidade Federal de Santa Catarina (HU/UFSC), Pathological Anatomy Service, Florian\u00f3polis, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I4104125","https://openalex.org/I4210126369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033712903","display_name":"Alcir Luiz Dafr\u00e9","orcid":"https://orcid.org/0000-0001-8097-4611","observed_orcids":["https://orcid.org/0000-0001-8097-4611"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alcir Luiz Dafre","raw_affiliation_strings":["Laboratory of Cellular Defense (LABDEF), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Cellular Defense (LABDEF), Universidade Federal de Santa Catarina (UFSC), Florian\u00f3polis, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071987052","display_name":"Deborah de Camargo Hizume Kunzler","orcid":"https://orcid.org/0000-0002-7954-3192","observed_orcids":["https://orcid.org/0000-0002-7954-3192"]},"institutions":[{"id":"https://openalex.org/I164790352","display_name":"Universidade do Estado de Santa Catarina","ror":"https://ror.org/03ztsbk67","country_code":"BR","type":"education","lineage":["https://openalex.org/I164790352"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Deborah de Camargo Hizume Kunzler","raw_affiliation_strings":["Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil. deborah.hizume@udesc.br","Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-7954-3192","affiliations":[{"raw_affiliation_string":"Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil. deborah.hizume@udesc.br","institution_ids":["https://openalex.org/I164790352"]},{"raw_affiliation_string":"Universidade Estadual de Santa Catarina (UDESC), Physical Therapy Graduate Program (PPG-Ft), Health and Sport Sciences Center (CEFID), Experimental Research Laboratory (LaPEx), R. Pascoal Simone, 358, Coqueiros, Florian\u00f3polis, ZIP Code: 88080-350, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I164790352"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5071987052"],"corresponding_institution_ids":["https://openalex.org/I164790352"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":0.4495,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.52988474,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"45","issue":"5","first_page":"1895","last_page":"1910"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.47049999237060547,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.47049999237060547,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.4357999861240387,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.0608999989926815,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aerobic-exercise","display_name":"aerobic exercise","score":0.9829999804496765},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.9959999918937683},{"id":"https://openalex.org/keywords/adenine-induced-kidney-injury","display_name":"adenine-induced kidney injury","score":0.8600000143051147},{"id":"https://openalex.org/keywords/lung-oxidative-stress","display_name":"lung oxidative stress","score":0.6489999890327454},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.7979999780654907},{"id":"https://openalex.org/keywords/pulmonary-fibrosis","display_name":"pulmonary fibrosis","score":0.597000002861023},{"id":"https://openalex.org/keywords/physical-performance","display_name":"physical performance","score":0.7369999885559082},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7279999852180481},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.921999990940094},{"id":"https://openalex.org/keywords/glutathione-peroxidase","display_name":"glutathione peroxidase","score":1.0},{"id":"https://openalex.org/keywords/leukocyte-infiltration","display_name":"leukocyte infiltration","score":0.7730000019073486},{"id":"https://openalex.org/keywords/pulmonary-edema","display_name":"pulmonary edema","score":0.5870000123977661},{"id":"https://openalex.org/keywords/exercise-training","display_name":"exercise training","score":0.40700000524520874}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7135277390480042},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.7070802450180054},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6408968567848206},{"id":"https://openalex.org/C2777961210","wikidata":"https://www.wikidata.org/wiki/Q927148","display_name":"Bronchoalveolar lavage","level":3,"score":0.5784156322479248},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5723376274108887},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.5109209418296814},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.4718869924545288},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.4456711411476135},{"id":"https://openalex.org/C2780886150","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Edema","level":2,"score":0.4113346338272095},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.315945565700531}],"mesh":[{"descriptor_ui":"D000076604","descriptor_name":"Physical Functional Performance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000225","descriptor_name":"Adenine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002374","descriptor_name":"Catalase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003404","descriptor_name":"Creatinine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005979","descriptor_name":"Glutathione Peroxidase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014508","descriptor_name":"Urea","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10753-022-01643-y","doi":"https://doi.org/10.1007/s10753-022-01643-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10753-022-01643-y","pdf_url":null,"source":{"id":"https://openalex.org/S127393932","display_name":"Inflammation","issn_l":"0360-3997","issn":["0360-3997","1573-2576"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation","raw_type":"journal-article"},{"id":"pmid:35727396","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35727396","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inflammation","raw_type":"Journal Article"},{"id":"pmh:oai:repositorio.udesc.br:UDESC/2883","doi":null,"is_oa":true,"landing_page_url":"https://repositorio.udesc.br/handle/UDESC/2883","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UDESC","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"pmh:oai:repositorio.udesc.br:UDESC/2883","doi":null,"is_oa":true,"landing_page_url":"https://repositorio.udesc.br/handle/UDESC/2883","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UDESC","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W191793640","https://openalex.org/W1122013619","https://openalex.org/W1567614586","https://openalex.org/W1580052517","https://openalex.org/W1593555249","https://openalex.org/W1957149007","https://openalex.org/W1972523793","https://openalex.org/W1978103463","https://openalex.org/W1997875060","https://openalex.org/W2004672350","https://openalex.org/W2013259362","https://openalex.org/W2018823412","https://openalex.org/W2020140293","https://openalex.org/W2031660618","https://openalex.org/W2040660399","https://openalex.org/W2047136712","https://openalex.org/W2058848912","https://openalex.org/W2063009421","https://openalex.org/W2066781830","https://openalex.org/W2069171119","https://openalex.org/W2069367967","https://openalex.org/W2085349520","https://openalex.org/W2103650142","https://openalex.org/W2114758077","https://openalex.org/W2122275658","https://openalex.org/W2128131834","https://openalex.org/W2139044647","https://openalex.org/W2154100579","https://openalex.org/W2163076045","https://openalex.org/W2165753570","https://openalex.org/W2166994075","https://openalex.org/W2170595123","https://openalex.org/W2171561094","https://openalex.org/W2197332903","https://openalex.org/W2318453837","https://openalex.org/W2342601477","https://openalex.org/W2405183840","https://openalex.org/W2410181740","https://openalex.org/W2529933645","https://openalex.org/W2579711112","https://openalex.org/W2602758276","https://openalex.org/W2604762091","https://openalex.org/W2605904417","https://openalex.org/W2606066898","https://openalex.org/W2606350880","https://openalex.org/W2609982078","https://openalex.org/W2616194894","https://openalex.org/W2710302514","https://openalex.org/W2770077515","https://openalex.org/W2776204365","https://openalex.org/W2784962730","https://openalex.org/W2804933920","https://openalex.org/W2884792081","https://openalex.org/W2886076351","https://openalex.org/W2913397085","https://openalex.org/W2975946936","https://openalex.org/W2982354070","https://openalex.org/W2989393886","https://openalex.org/W3042588027","https://openalex.org/W4211214771","https://openalex.org/W4229508150","https://openalex.org/W4251567075"],"related_works":["https://openalex.org/W2770077515","https://openalex.org/W4387077739","https://openalex.org/W2955001452","https://openalex.org/W2004672350","https://openalex.org/W4416537878","https://openalex.org/W4206408852","https://openalex.org/W2047136712","https://openalex.org/W4391062897","https://openalex.org/W2776204365","https://openalex.org/W7120352512"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-06-22T00:00:00"}