{"id":"https://openalex.org/W4283028112","doi":"https://doi.org/10.1097/01.mat.0000840876.98438.70","title":"CARC3: Characterizing Audio Traits of Various Systemic to Pulmonary Connections in Ductal Dependent Infants","display_name":"CARC3: Characterizing Audio Traits of Various Systemic to Pulmonary Connections in Ductal Dependent Infants","publication_year":2022,"publication_date":"2022-06-01","ids":{"openalex":"https://openalex.org/W4283028112","doi":"https://doi.org/10.1097/01.mat.0000840876.98438.70"},"language":"en","primary_location":{"id":"doi:10.1097/01.mat.0000840876.98438.70","doi":"https://doi.org/10.1097/01.mat.0000840876.98438.70","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.mat.0000840876.98438.70","pdf_url":null,"source":{"id":"https://openalex.org/S8999885","display_name":"ASAIO Journal","issn_l":"1058-2916","issn":["1058-2916","1538-943X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ASAIO Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014562317","display_name":"Zahidee Rodriguez","orcid":"https://orcid.org/0000-0002-0804-7132","observed_orcids":["https://orcid.org/0000-0002-0804-7132"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zahidee Rodriguez","raw_affiliation_strings":["Pediatrics, Emory University SOM, Atlanta, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, Emory University SOM, Atlanta, GA, United States","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Camille Johnson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Camille Johnson","raw_affiliation_strings":["Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045929691","display_name":"Alaa Aljiffry","orcid":"https://orcid.org/0000-0003-1338-3242","observed_orcids":["https://orcid.org/0000-0003-1338-3242"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alaa Aljiffry","raw_affiliation_strings":["Pediatrics, Emory University SOM, Atlanta, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, Emory University SOM, Atlanta, GA, United States","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016304738","display_name":"Goktug Cihan Ozmen","orcid":"https://orcid.org/0000-0002-5930-6819","observed_orcids":["https://orcid.org/0000-0002-5930-6819"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Goktug Ozmen","raw_affiliation_strings":["Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114183146","display_name":"Brooke Seitter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146983","display_name":"Children's Healthcare of Atlanta","ror":"https://ror.org/050fhx250","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210146983"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brooke Seitter","raw_affiliation_strings":["Children\u2019s Hospital of Atlanta, Atlanta, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children\u2019s Hospital of Atlanta, Atlanta, GA, United States","institution_ids":["https://openalex.org/I4210146983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016806649","display_name":"Kevin O'D. Maher","orcid":"https://orcid.org/0000-0001-6445-0228","observed_orcids":["https://orcid.org/0000-0001-6445-0228"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin Maher","raw_affiliation_strings":["Pediatrics, Emory University SOM, Atlanta, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, Emory University SOM, Atlanta, GA, United States","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076927036","display_name":"Omer T. Inan","orcid":"https://orcid.org/0000-0002-7952-1794","observed_orcids":["https://orcid.org/0000-0002-7952-1794"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omer Inan","raw_affiliation_strings":["Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States","institution_ids":["https://openalex.org/I130701444"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11390262,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"68","issue":"Supplement 2","first_page":"29","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12419","display_name":"Phonocardiography and Auscultation Techniques","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12419","display_name":"Phonocardiography and Auscultation Techniques","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.06610000133514404,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.011800000444054604,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/congenital-heart-disease","display_name":"congenital heart disease","score":0.9449999928474426},{"id":"https://openalex.org/keywords/phonocardiogram","display_name":"phonocardiogram","score":0.8880000114440918},{"id":"https://openalex.org/keywords/blalock-taussig-shunt","display_name":"Blalock-Taussig shunt","score":0.8410000205039978},{"id":"https://openalex.org/keywords/sano-shunt","display_name":"Sano shunt","score":0.9120000004768372},{"id":"https://openalex.org/keywords/wavelet-denoising","display_name":"wavelet denoising","score":0.6840000152587891},{"id":"https://openalex.org/keywords/audio-feature-extraction","display_name":"audio feature extraction","score":0.8410000205039978},{"id":"https://openalex.org/keywords/non-invasive-monitoring","display_name":"non-invasive monitoring","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6854745149612427},{"id":"https://openalex.org/C2780968331","wikidata":"https://www.wikidata.org/wiki/Q1890115","display_name":"Shunt (medical)","level":2,"score":0.635993480682373},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.5356829166412354},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5241411328315735},{"id":"https://openalex.org/C2779055095","wikidata":"https://www.wikidata.org/wiki/Q162339","display_name":"Stethoscope","level":2,"score":0.4896572232246399},{"id":"https://openalex.org/C2780940725","wikidata":"https://www.wikidata.org/wiki/Q206280","display_name":"Pulmonary artery","level":2,"score":0.47919023036956787},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.439777672290802},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3292965292930603}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/01.mat.0000840876.98438.70","doi":"https://doi.org/10.1097/01.mat.0000840876.98438.70","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.mat.0000840876.98438.70","pdf_url":null,"source":{"id":"https://openalex.org/S8999885","display_name":"ASAIO Journal","issn_l":"1058-2916","issn":["1058-2916","1538-943X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ASAIO Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8700000047683716,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4392449560","https://openalex.org/W4390453131","https://openalex.org/W2894979342","https://openalex.org/W205295401","https://openalex.org/W2384993490","https://openalex.org/W2791057069","https://openalex.org/W4391680328","https://openalex.org/W4213293560","https://openalex.org/W2102755493","https://openalex.org/W2795120748"],"abstract_inverted_index":{"Background:":[0],"Infants":[1],"with":[2,85,126],"congenital":[3],"heart":[4],"disease":[5],"who":[6,196],"have":[7,44],"insufficient":[8],"systemic":[9,19],"or":[10],"pulmonary":[11,21,32],"blood":[12],"flow":[13],"require":[14],"a":[15,45,57,62,127,177,228,247,262,282],"connection":[16],"between":[17],"the":[18,67,123,159,204],"and":[20,38,50,97,114,136,141,145,153,168,193,218,243,267,287],"vasculature.":[22],"There":[23],"are":[24],"four":[25],"types":[26,270,290],"of":[27,48,70,99],"shunts:":[28],"right":[29],"ventricle":[30],"to":[31,65,133,210,246,251],"artery":[33],"(Sano),":[34],"Blalock-TaussigThomas":[35],"(BTTS),":[36],"central,":[37],"ductal":[39],"arterial":[40],"stent":[41],"(DAS).":[42],"They":[43],"high":[46],"incidence":[47],"mortality":[49],"unplanned":[51],"interventions.":[52],"Machine":[53],"learning":[54],"algorithms":[55],"evaluate":[56],"shunt":[58,86,100,211,231,240,253,269,289],"murmur":[59],"recorded":[60],"on":[61,88,239],"digital":[63],"stethoscope":[64],"differentiate":[66],"audio":[68,147],"features":[69,175],"various":[71],"shunts.":[72],"Methods:":[73],"A":[74,118,161],"3M":[75],"Littman":[76],"Electronic":[77],"Stethoscope":[78],"acquired":[79],"phonocardiogram":[80],"(PCG)":[81],"data":[82,125],"from":[83,131,158,271,291],"infants":[84],"placement":[87],"post-operative":[89],"days":[90],"0,":[91],"1,":[92],"2,":[93],"7,":[94],"14,":[95],"discharge":[96],"day":[98],"take-down,":[101],"as":[102],"well":[103],"as,":[104],"when":[105],"imaging":[106],"(echo,":[107],"CT,":[108],"catheterization)":[109],"was":[110],"performed.":[111],"Patient":[112],"demographics":[113],"clinical":[115],"outcomes":[116],"noted.":[117],"wavelet":[119],"decomposition":[120],"algorithm":[121,163],"denoised":[122],"PCG":[124],"bandpass":[128],"filter":[129],"ranging":[130],"20":[132],"2000":[134],"Hz":[135],"then":[137],"segmented":[138],"into":[139],"S1":[140],"S2.":[142],"One":[143],"hundred":[144],"fifteen":[146],"features,":[148],"comprising":[149],"temporal,":[150],"spectral,":[151],"statistical,":[152],"bandpower":[154],"domains":[155],"were":[156,201],"extracted":[157],"waveforms.":[160],"statistical":[162],"including":[164],"ANOVA,":[165],"Kruskal":[166],"Wallis":[167],"pairwise":[169],"comparison":[170],"tests":[171],"detected":[172],"33":[173],"total":[174],"showing":[176],"statistically":[178],"significant":[179],"difference":[180],"in":[181,264,284],"means":[182],"(alpha":[183],"=":[184],"0.05).":[185],"Results:":[186],"Thirteen":[187],"subjects":[188],"(BTTS":[189],"(n=3),":[190],"DAS":[191],"(n=2),":[192],"Sano":[194],"(n=8))":[195],"had":[197],"second":[198],"stage":[199],"palliation":[200],"analyzed":[202],"using":[203],"two":[205],"most":[206],"recent":[207],"recordings":[208],"prior":[209],"takedown.":[212],"Principal":[213,257],"component":[214],"analysis":[215],"(Figure":[216,223],"1)":[217],"tdistributed":[219],"stochastic":[220,277],"neighbor":[221,278],"embedding":[222,279],"2)":[224],"visualization":[225],"techniques":[226],"indicate":[227],"separation":[229,263,283],"among":[230],"types.":[232],"Conclusion:":[233],"Audio":[234],"signatures":[235],"could":[236],"exist":[237],"based":[238],"type":[241],"characteristics":[242],"may":[244],"lead":[245],"novel":[248],"non-invasive":[249],"tool":[250],"monitor":[252],"health.":[254],"Figure":[255,274],"1.":[256],"Component":[258],"Analysis":[259],"(PCA)":[260],"indicating":[261,281],"BTTS,":[265,285],"Sano,":[266,286],"PDA":[268,288],"selected":[272,292],"recordings.":[273,293],"2.":[275],"t-distributed":[276],"(tSNE)":[280]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2022-06-18T00:00:00"}