{"id":"https://openalex.org/W4283021916","doi":"https://doi.org/10.1016/s0016-5085(22)63726-0","title":"Tu1305: USING A HUMAN 3-D COCULTURE SYSTEM TO EXPLORE SPTBN1 AS A THERAPEUTIC NASH TARGET","display_name":"Tu1305: USING A HUMAN 3-D COCULTURE SYSTEM TO EXPLORE SPTBN1 AS A THERAPEUTIC NASH TARGET","publication_year":2022,"publication_date":"2022-05-01","ids":{"openalex":"https://openalex.org/W4283021916","doi":"https://doi.org/10.1016/s0016-5085(22)63726-0"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(22)63726-0","doi":"https://doi.org/10.1016/s0016-5085(22)63726-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(22)63726-0","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056409786","display_name":"Nancy R. Gough","orcid":"https://orcid.org/0000-0001-5179-8890","observed_orcids":["https://orcid.org/0000-0001-5179-8890"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nancy R. Gough","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068546735","display_name":"Xiyan Xiang","orcid":"https://orcid.org/0000-0002-4746-9522","observed_orcids":["https://orcid.org/0000-0002-4746-9522"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiyan Xiang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054498115","display_name":"Shuyun Rao","orcid":"https://orcid.org/0000-0002-1073-6682","observed_orcids":["https://orcid.org/0000-0002-1073-6682"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shuyun Rao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101944720","display_name":"Xiaochun Yang","orcid":"https://orcid.org/0009-0007-7441-6390","observed_orcids":["https://orcid.org/0009-0007-7441-6390"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaochun Yang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026813679","display_name":"Kazufumi Ohshiro","orcid":"https://orcid.org/0000-0002-5162-5612","observed_orcids":["https://orcid.org/0000-0002-5162-5612"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazufumi Ohshiro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011759459","display_name":"Patricia S. Latham","orcid":"https://orcid.org/0000-0003-2782-9444","observed_orcids":["https://orcid.org/0000-0003-2782-9444"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patricia S. Latham","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076758530","display_name":"Wilma SR Jogunoori","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wilma Jogunoori","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034942083","display_name":"Kirti Shetty","orcid":"https://orcid.org/0000-0002-7725-6050","observed_orcids":["https://orcid.org/0000-0002-7725-6050"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kirti Shetty","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035321510","display_name":"Mich\u00e8le Vacca","orcid":"https://orcid.org/0000-0002-1973-224X","observed_orcids":["https://orcid.org/0000-0002-1973-224X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michele Vacca","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014810730","display_name":"Antonio Vidal\u2010Puig","orcid":"https://orcid.org/0000-0003-4220-9577","observed_orcids":["https://orcid.org/0000-0003-4220-9577"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Antonio Vidal-Puig","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076899472","display_name":"Gareth Guenigault","orcid":"https://orcid.org/0000-0002-0294-8677","observed_orcids":["https://orcid.org/0000-0002-0294-8677"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gareth Guenigault","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5091703176","display_name":"Lopa Mishra","orcid":"https://orcid.org/0000-0002-6850-0808","observed_orcids":["https://orcid.org/0000-0002-6850-0808"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lopa Mishra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"162","issue":"7","first_page":"S","last_page":"1268"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9437999725341797,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9437999725341797,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.013299999758601189,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sptbn1","display_name":"SPTBN1","score":0.9639999866485596},{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.8880000114440918},{"id":"https://openalex.org/keywords/human-liver-organoids","display_name":"human liver organoids","score":0.593999981880188},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.8270000219345093},{"id":"https://openalex.org/keywords/hepatic-stellate-cells","display_name":"hepatic stellate cells","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3890549838542938}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(22)63726-0","doi":"https://doi.org/10.1016/s0016-5085(22)63726-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(22)63726-0","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4410171150","https://openalex.org/W4410871320","https://openalex.org/W2802627174","https://openalex.org/W2916631807","https://openalex.org/W7160039127","https://openalex.org/W3027617376","https://openalex.org/W7144845177","https://openalex.org/W3026366901","https://openalex.org/W7145570338","https://openalex.org/W2606204944"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2022-06-18T00:00:00"}