{"id":"https://openalex.org/W4282983199","doi":"https://doi.org/10.3389/froh.2022.904711","title":"Influence of Oral Microbiota on the Presence of IgA Anti-Citrullinated Protein Antibodies in Gingival Crevicular Fluid","display_name":"Influence of Oral Microbiota on the Presence of IgA Anti-Citrullinated Protein Antibodies in Gingival Crevicular Fluid","publication_year":2022,"publication_date":"2022-06-16","ids":{"openalex":"https://openalex.org/W4282983199","doi":"https://doi.org/10.3389/froh.2022.904711","pmid":"https://pubmed.ncbi.nlm.nih.gov/35784663","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9243218"},"language":"en","primary_location":{"id":"doi:10.3389/froh.2022.904711","doi":"https://doi.org/10.3389/froh.2022.904711","is_oa":true,"landing_page_url":"https://doi.org/10.3389/froh.2022.904711","pdf_url":"https://www.frontiersin.org/articles/10.3389/froh.2022.904711/pdf","source":{"id":"https://openalex.org/S4210201735","display_name":"Frontiers in Oral Health","issn_l":"2673-4842","issn":["2673-4842"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oral Health","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/froh.2022.904711/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063010653","display_name":"Menke J. de Smit","orcid":"https://orcid.org/0000-0003-1863-0775","observed_orcids":["https://orcid.org/0000-0003-1863-0775"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Menke J. de Smit","raw_affiliation_strings":["Department of Dentistry, University Medical Center Groningen, University of Groningen, Groningen, Netherlands","Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dentistry, University Medical Center Groningen, University of Groningen, Groningen, Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]},{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037942923","display_name":"Poerwati Soetji Rahajoe","orcid":"https://orcid.org/0000-0002-5560-6945","observed_orcids":["https://orcid.org/0000-0002-5560-6945"]},"institutions":[{"id":"https://openalex.org/I4210157242","display_name":"Rumah Sakit Umum Pusat Dr. Sardjito","ror":"https://ror.org/05wwwfn44","country_code":"ID","type":"healthcare","lineage":["https://openalex.org/I4210157242"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Poerwati Soetji Rahajoe","raw_affiliation_strings":["Department of Oral Surgery, Dr. Sardjito General Hospital, Yogyakarta, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Surgery, Dr. Sardjito General Hospital, Yogyakarta, Indonesia","institution_ids":["https://openalex.org/I4210157242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034731250","display_name":"Elisabeth Raveling\u2010Eelsing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Elisabeth Raveling-Eelsing","raw_affiliation_strings":["Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026251485","display_name":"Paola Lisotto","orcid":"https://orcid.org/0000-0003-1402-9499","observed_orcids":["https://orcid.org/0000-0003-1402-9499"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Paola Lisotto","raw_affiliation_strings":["Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000398093","display_name":"Hermie J. M. Harmsen","orcid":"https://orcid.org/0000-0003-2725-6148","observed_orcids":["https://orcid.org/0000-0003-2725-6148"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Hermie J. M. Harmsen","raw_affiliation_strings":["Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010859304","display_name":"Nyoman Kertia","orcid":"https://orcid.org/0009-0005-5319-945X","observed_orcids":["https://orcid.org/0009-0005-5319-945X"]},"institutions":[{"id":"https://openalex.org/I4210157242","display_name":"Rumah Sakit Umum Pusat Dr. Sardjito","ror":"https://ror.org/05wwwfn44","country_code":"ID","type":"healthcare","lineage":["https://openalex.org/I4210157242"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Nyoman Kertia","raw_affiliation_strings":["Department of Rheumatology, Dr. Sardjito General Hospital, Yogyakarta, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Dr. Sardjito General Hospital, Yogyakarta, Indonesia","institution_ids":["https://openalex.org/I4210157242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078999248","display_name":"Arjan Vissink","orcid":"https://orcid.org/0000-0003-2581-4361","observed_orcids":["https://orcid.org/0000-0003-2581-4361"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Arjan Vissink","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013575183","display_name":"Johanna Westra","orcid":"https://orcid.org/0000-0002-6581-6508","observed_orcids":["https://orcid.org/0000-0002-6581-6508"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Johanna Westra","raw_affiliation_strings":["Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5013575183"],"corresponding_institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":1.1884,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.73210863,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"3","issue":null,"first_page":"904711","last_page":"904711"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/periodontitis","display_name":"periodontitis","score":0.7459999918937683},{"id":"https://openalex.org/keywords/oral-microbiota","display_name":"oral microbiota","score":0.7919999957084656},{"id":"https://openalex.org/keywords/subgingival-microbiota","display_name":"subgingival microbiota","score":0.9490000009536743},{"id":"https://openalex.org/keywords/gingival-crevicular-fluid","display_name":"gingival crevicular fluid","score":0.9629999995231628},{"id":"https://openalex.org/keywords/porphyromonas-gingivalis","display_name":"Porphyromonas gingivalis","score":0.9089999794960022},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.7450000047683716},{"id":"https://openalex.org/keywords/autoantibodies","display_name":"autoantibodies","score":0.7379999756813049},{"id":"https://openalex.org/keywords/beta-diversity","display_name":"beta diversity","score":0.6460000276565552},{"id":"https://openalex.org/keywords/neisseriaceae","display_name":"Neisseriaceae","score":0.8259999752044678},{"id":"https://openalex.org/keywords/haemophilus","display_name":"Haemophilus","score":0.890999972820282},{"id":"https://openalex.org/keywords/tannerella","display_name":"Tannerella","score":0.9649999737739563},{"id":"https://openalex.org/keywords/16s-rrna-gene-sequencing","display_name":"16S rRNA gene sequencing","score":0.8100000023841858}],"concepts":[{"id":"https://openalex.org/C2780183776","wikidata":"https://www.wikidata.org/wiki/Q3214147","display_name":"Porphyromonas gingivalis","level":3,"score":0.7894629836082458},{"id":"https://openalex.org/C2780385504","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontitis","level":2,"score":0.6070706844329834},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5511995553970337},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5308262705802917},{"id":"https://openalex.org/C2779102806","wikidata":"https://www.wikidata.org/wiki/Q79453","display_name":"Immunoglobulin A","level":4,"score":0.527057409286499},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.513839066028595},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.4869931638240814},{"id":"https://openalex.org/C2779337755","wikidata":"https://www.wikidata.org/wiki/Q5113988","display_name":"Chronic periodontitis","level":3,"score":0.4746692180633545},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.4655827581882477},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.4433269202709198},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4388335943222046},{"id":"https://openalex.org/C2778380114","wikidata":"https://www.wikidata.org/wiki/Q143652","display_name":"Periodontium","level":2,"score":0.417820006608963},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31790024042129517},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.2952668070793152},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22787514328956604},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.15256166458129883},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3389/froh.2022.904711","doi":"https://doi.org/10.3389/froh.2022.904711","is_oa":true,"landing_page_url":"https://doi.org/10.3389/froh.2022.904711","pdf_url":"https://www.frontiersin.org/articles/10.3389/froh.2022.904711/pdf","source":{"id":"https://openalex.org/S4210201735","display_name":"Frontiers in Oral Health","issn_l":"2673-4842","issn":["2673-4842"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oral Health","raw_type":"journal-article"},{"id":"pmid:35784663","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35784663","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in oral health","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9243218","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9243218/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Oral Health","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:024ff6171378496ebf71e8ee070e8a2e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/024ff6171378496ebf71e8ee070e8a2e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Oral Health, Vol 3 (2022)","raw_type":"article"},{"id":"pmh:oai:pure.rug.nl:openaire/d763328a-c9e5-47d7-b9fc-ae9627b67006","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11370/d763328a-c9e5-47d7-b9fc-ae9627b67006","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"de Smit, M J, Rahajoe, P S, Raveling-Eelsing, E, Lisotto, P, Harmsen, H J M, Kertia, N, Vissink, A & Westra, J 2022, 'Influence of Oral Microbiota on the Presence of IgA Anti-Citrullinated Protein Antibodies in Gingival Crevicular Fluid', Frontiers in oral health, vol. 3, pp. 904711. https://doi.org/10.3389/froh.2022.904711","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/d763328a-c9e5-47d7-b9fc-ae9627b67006","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/d763328a-c9e5-47d7-b9fc-ae9627b67006","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in oral health, 3","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3389/froh.2022.904711","doi":"https://doi.org/10.3389/froh.2022.904711","is_oa":true,"landing_page_url":"https://doi.org/10.3389/froh.2022.904711","pdf_url":"https://www.frontiersin.org/articles/10.3389/froh.2022.904711/pdf","source":{"id":"https://openalex.org/S4210201735","display_name":"Frontiers in Oral Health","issn_l":"2673-4842","issn":["2673-4842"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Oral Health","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320933","display_name":"Rijksuniversiteit Groningen","ror":"https://ror.org/012p63287"},{"id":"https://openalex.org/F4320323768","display_name":"ReumaNederland","ror":"https://ror.org/05dr3r825"},{"id":"https://openalex.org/F4320331585","display_name":"Dutch Arthritis Association","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4282983199.pdf","grobid_xml":"https://content.openalex.org/works/W4282983199.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1533294137","https://openalex.org/W1793781511","https://openalex.org/W1998890104","https://openalex.org/W2002401357","https://openalex.org/W2017290170","https://openalex.org/W2096508681","https://openalex.org/W2107005433","https://openalex.org/W2107882417","https://openalex.org/W2118241494","https://openalex.org/W2131758159","https://openalex.org/W2168104108","https://openalex.org/W2228209443","https://openalex.org/W2252685669","https://openalex.org/W2404222461","https://openalex.org/W2527830751","https://openalex.org/W2560381583","https://openalex.org/W2562800512","https://openalex.org/W2745725076","https://openalex.org/W2767326710","https://openalex.org/W2789338827","https://openalex.org/W2792301451","https://openalex.org/W2886363262","https://openalex.org/W2890131570","https://openalex.org/W2900897746","https://openalex.org/W2944468995","https://openalex.org/W2952739891","https://openalex.org/W2952834456","https://openalex.org/W3002450955","https://openalex.org/W3003881724","https://openalex.org/W3009628192","https://openalex.org/W3090962484","https://openalex.org/W3121536476","https://openalex.org/W3158437730","https://openalex.org/W3164839261","https://openalex.org/W3188035359","https://openalex.org/W3199078719","https://openalex.org/W3200314837","https://openalex.org/W3201252426","https://openalex.org/W4200186639"],"related_works":["https://openalex.org/W2617020002","https://openalex.org/W2899026461","https://openalex.org/W2755421403","https://openalex.org/W3009628192","https://openalex.org/W2903368716","https://openalex.org/W2909665751","https://openalex.org/W4294308101","https://openalex.org/W2916082128","https://openalex.org/W2111496861","https://openalex.org/W3164363378"],"abstract_inverted_index":{"Introduction":[0],"The":[1,74],"relation":[2],"between":[3,170,211,230,257],"rheumatoid":[4],"arthritis":[5],"(RA)":[6],"and":[7,56,105,114,128,135,180,221,318,341],"periodontitis":[8],"(PD)":[9],"has":[10],"been":[11],"investigated":[12],"ever":[13],"since":[14],"the":[15,18,26,35,64,71,83,89,95,151,254,307,324,352,358],"discovery":[16],"of":[17,37,41,52,67,76,91,97,150,355],"citrullinating":[19],"enzyme":[20],"peptidyl":[21],"arginine":[22],"deaminase":[23],"presents":[24],"in":[25,47,70,94,120,145,178,198,202,226,237,253,268,283,290,298,305,323,329,337,357],"oral":[27],"bacterium":[28],"Porphyromonas":[29,271,345],"gingivalis":[30],".":[31],"Recently,":[32],"we":[33],"demonstrated":[34],"presence":[36,90,354],"RA":[38,58,68],"autoantibodies,":[39],"especially":[40],"IgA":[42,92,116,143,176,196,235,260,266,288,296,327,335],"anti-citrullinated":[43],"protein":[44],"antibody":[45],"(ACPA),":[46],"gingival":[48],"crevicular":[49],"fluid":[50],"(GCF)":[51],"Indonesian":[53],"patients":[54],"with":[55,100,109,138,173,181,188,193,213,228,232,259,286,309,326,351],"without":[57,102,142,175,183,190,195,215,234,265,295,334],"or":[59,101,174,182,189,192,194,214,233],"PD":[60,216,229],"which":[61],"might":[62],"indicate":[63],"local":[65,353],"formation":[66],"antibodies":[69],"periodontium.":[72,359],"Aim":[73],"purpose":[75],"this":[77],"study":[78],"was":[79,154,209,224,272,280],"to":[80,88,166,263,293,332,348],"assess":[81,167],"whether":[82],"subgingival":[84,152],"microbiome":[85,153],"is":[86],"related":[87],"ACPA":[93,117,144,177,197,236,261,267,289,297,328,336,356],"GCF":[96,121,179,238,291,299,330],"healthy":[98,140,171,284],"individuals":[99,108,141,285,294],"PD.":[103,184],"Patients":[104],"Methods":[106],"Healthy":[107],"a":[110,222],"known":[111],"periodontal":[112,133],"status":[113,137],"high":[115,287],"(>0.1":[118],"U/ml)":[119],"(":[122,217,239,300],"n":[123],"=":[124,241,302],"27)":[125],"were":[126,164,205,320],"selected":[127],"matched":[129],"for":[130],"age,":[131],"gender,":[132],"status,":[134],"smoking":[136],"27":[139],"their":[146],"GCF.":[147,269,338],"Taxonomic":[148],"profiling":[149],"based":[155],"on":[156,306],"bacterial":[157],"16S":[158],"rRNA":[159],"gene":[160],"sequencing.":[161],"Downstream":[162],"analyses":[163],"performed":[165],"compositional":[168],"differences":[169,201,252],"subjects":[172,227,231,258,264,325,333],"Results":[185],"Between":[186],"groups":[187,212],"PD,":[191,310],"GCF,":[199],"no":[200,250],"alpha":[203],"diversity":[204,208],"seen.":[206],"Beta":[207],"different":[210],"p":[218,240,301],"<":[219],"0.0001),":[220],"trend":[223],"seen":[225],"0.084).":[242],"Linear":[243],"discriminant":[244],"analysis":[245],"effect":[246],"size":[247],"(LEfSe)":[248],"revealed":[249,312],"significant":[251],"total":[255],"population":[256],"compared":[262,292,331],"Although":[270],"not":[273],"identified":[274],"by":[275],"LEfSe,":[276],"its":[277],"relative":[278],"abundance":[279],"significantly":[281],"higher":[282],"0.0363).":[303],"Zooming":[304],"subgroup":[308],"LEfSe":[311],"that":[313],"species":[314],"Neisseriaceae,":[315],"Tannerella":[316],",":[317,346],"Haemophilus":[319],"more":[321],"abundant":[322],"Conclusion":[339],"Periodontitis":[340],"certain":[342],"taxa,":[343],"including":[344],"seem":[347],"be":[349],"associated":[350]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-06-17T00:00:00"}